Noncoding RNAs in Nonalcoholic Fatty Liver Disease: Potential Diagnosis and Prognosis Biomarkers

The Roles and Mechanisms of lncRNAs in Liver Fibrosis

(2020) Zhi He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Regulatory Non-coding RNAs Network in Non-alcoholic Fatty Liver Disease

(2019) Siti Aishah Sulaiman et al.   Frontiers in Physiology

Role of Noncoding RNA in Development of Nonalcoholic Fatty Liver Disease

(2019) Ruixian Huang et al.   Biomed Research International

GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network

(2019) Bahram Namjou et al.   BMC Medicine

Special Issue: MicroRNA Regulation in Health and Disease

(2019) Subbaya Subramanian et al.   Genes

Circulating MicroRNAs in Cancer: Potential and Challenge

(2019) Mengying Cui et al.   Frontiers in Genetics

Circular RNAs: Biogenesis, Mechanism, and Function in Human Cancers

(2019) Xing Zhao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Research progress on the interactions between long non‑coding RNAs and microRNAs in human cancer (Review)

(2019) Binyu Sun et al.   Oncology Letters

Functional Classification and Experimental Dissection of Long Noncoding RNAs

(2018) Florian Kopp et al.   CELL

Global epidemiology of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: What we need in the future

(2018) Ana Ruth Araújo et al.   LIVER INTERNATIONAL

circRNA_0046366 inhibits hepatocellular steatosis by normalization of PPAR signaling

(2018) Xing-Ya Guo et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Oxidative stress preconditioning of mouse perivascular myogenic progenitors selects a subpopulation of cells with a distinct survival advantage in vitro and in vivo

(2018) Cesare Gargioli et al.   Cell Death & Disease

Non-invasive prediction of NAFLD severity: a comprehensive, independent validation of previously postulated serum microRNA biomarkers

(2018) Mireia López-Riera et al.   Scientific Reports

Preliminary screening and functional analysis of circular RNAs associated with hepatic stellate cell activation

(2018) Yuping Zhou et al.   GENE

Non-coding transcript variants of protein-coding genes – what are they good for?

(2018) Sonam Dhamija et al.   RNA Biology

Role of microRNAs in alcohol-induced liver disorders and non-alcoholic fatty liver disease

(2018) Jorge-Luis Torres et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Circular RNAs: Promising Biomarkers for Human Diseases

(2018) Zhongrong Zhang et al.   EBioMedicine

Molecular pathways of nonalcoholic fatty liver disease development and progression

(2018) Fernando Bessone et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

miRNA Signature in NAFLD: A Turning Point for a Non-Invasive Diagnosis

(2018) Paola Dongiovanni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A polymorphism in the Irisin-encoding gene (FNDC5) associates with hepatic steatosis by differential miRNA binding to the 3′UTR

(2018) Mayada Metwally et al.   JOURNAL OF HEPATOLOGY

Microarray profiling of circular RNAs and the potential regulatory role of hsa_circ_0071410 in the activated human hepatic stellate cell induced by irradiation

(2017) Yuhan Chen et al.   GENE

Down-regulation of lncRNA-NEAT1 alleviated the non-alcoholic fatty liver disease via mTOR/S6K1 signaling pathway

(2017) Xiang Wang   JOURNAL OF CELLULAR BIOCHEMISTRY

NEAT1 accelerates the progression of liver fibrosis via regulation of microRNA-122 and Kruppel-like factor 6

(2017) Fujun Yu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The epidemiology of non-alcoholic fatty liver disease

(2017) Stefano Bellentani   LIVER INTERNATIONAL

CircRNA: functions and properties of a novel potential biomarker for cancer

(2017) Shujuan Meng et al.   Molecular Cancer

Expression of cyclooxygenase-2 is correlated with lncRNA-COX-2 in cirrhotic mice induced by carbon tetrachloride

(2017) Shi-Hang Tang et al.   Molecular Medicine Reports

Disease progression: Divergent paths

(2017)   NATURE

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

(2017) Zobair Younossi et al.   Nature Reviews Gastroenterology & Hepatology

Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis

(2017) Anna M. Diehl et al.   NEW ENGLAND JOURNAL OF MEDICINE

circRNA_0046367 Prevents Hepatoxicity of Lipid Peroxidation: An Inhibitory Role against Hepatic Steatosis

(2017) Xing-Ya Guo et al.   Oxidative Medicine and Cellular Longevity

Altered expression of MALAT1 lncRNA in nonalcoholic steatohepatitis fibrosis regulates CXCL5 in hepatic stellate cells

(2017) Fatjon Leti et al.   Translational Research

Clinical epidemiology and disease burden of nonalcoholic fatty liver disease

(2017) Brandon J Perumpail et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Long noncoding RNA NEAT1 promotes cell proliferation and invasion by regulating hnRNP A2 expression in hepatocellular carcinoma cells

(2017) Yuanyi Mang et al.   OncoTargets and Therapy

miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice

(2017) Pedro M Rodrigues et al.   Cell Death & Disease

Potential applications of MEG3 in cancer diagnosis and prognosis

(2017) Yuqing He et al.   Oncotarget

An emerging function of circRNA-miRNAs-mRNA axis in human diseases

(2017) Dawei Rong et al.   Oncotarget

Genetic Dissection of the Impact of miR-33a and miR-33b during the Progression of Atherosclerosis

(2017) Nathan L. Price et al.   Cell Reports

Circular RNA Profiling and Bioinformatic Modeling Identify Its Regulatory Role in Hepatic Steatosis

(2017) Xing-Ya Guo et al.   Biomed Research International

Up-regulated HOTAIR induced by fatty acids inhibits PTEN expression and increases triglycerides accumulation in HepG2 cells

(2017) Weiping Li et al.   Food & Nutrition Research

Role of MicroRNAs in NAFLD/NASH

(2016) Gyongyi Szabo et al.   DIGESTIVE DISEASES AND SCIENCES

The Natural Course of Non-Alcoholic Fatty Liver Disease

(2016) Luis Calzadilla Bertot et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mopping up miRNA: An integrated HBV transcript disrupts liver homeostasis by sequestering miR-122

(2016) Joseph M. Luna et al.   JOURNAL OF HEPATOLOGY

Management of NAFLD: a stage-based approach

(2016) Mary E. Rinella et al.   Nature Reviews Gastroenterology & Hepatology

Unique features of long non-coding RNA biogenesis and function

(2016) Jeffrey J. Quinn et al.   NATURE REVIEWS GENETICS

Association of Circulating Serum miR-34a and miR-122 with Dyslipidemia among Patients with Non-Alcoholic Fatty Liver Disease

(2016) Noel C. Salvoza et al.   PLoS One

Cytoplasmic long noncoding RNAs are frequently bound to and degraded at ribosomes in human cells

(2016) Joana Carlevaro-Fita et al.   RNA

CircRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of nonalcoholic steatohepatitis

(2016) Xi Jin et al.   Oncotarget

Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease

(2016) Valentina Cappello et al.   Scientific Reports

Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis

(2015) Diptadip Dattaroy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Long non-coding RNA APTR promotes the activation of hepatic stellate cells and the progression of liver fibrosis

(2015) Fujun Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Progress and Prospects of Long Noncoding RNAs (lncRNAs) in Hepatocellular Carcinoma

(2015) Chen Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

GWAS-Identified Common Variants With Nonalcoholic Fatty Liver Disease in Chinese Children

(2015) Xiao-Rui Shang et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

The role of fatty acids in insulin resistance

(2015) Barry Sears et al.   Lipids in Health and Disease

Performance of Serum microRNAs -122, -192 and -21 as Biomarkers in Patients with Non-Alcoholic Steatohepatitis

(2015) Philip P. Becker et al.   PLoS One

Regulation of circRNA biogenesis

(2015) Ling-Ling Chen et al.   RNA Biology

Genetic background in nonalcoholic fatty liver disease: A comprehensive review

(2015) Fabio Salvatore Macaluso   WORLD JOURNAL OF GASTROENTEROLOGY

Effect of miR-34a in regulating steatosis by targeting PPARα expression in nonalcoholic fatty liver disease

(2015) Jiexia Ding et al.   Scientific Reports

Long Non-Coding RNAs: Challenges for Diagnosis and Therapies

(2015) Yolanda Sánchez et al.   Nucleic Acid Therapeutics

Regulation of histone methylation by noncoding RNAs

(2014) Richard I. Joh et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Inhibitory effects of long noncoding RNA MEG3 on hepatic stellate cells activation and liver fibrogenesis

(2014) Yong He et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

MicroRNA-Management of Lipoprotein Homeostasis

(2014) Xinghui Sun et al.   CIRCULATION RESEARCH

Meta-Analysis of Associations Between the Peroxisome Proliferator-Activated Receptor-γ Pro12Ala Polymorphism and Susceptibility to Nonalcoholic Fatty Liver Disease, Rheumatoid Arthritis, and Psoriatic Arthritis

(2014) Young Ho Lee et al.   Genetic Testing and Molecular Biomarkers

Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis

(2014) Carlos J Pirola et al.   GUT

Long noncoding RNA in liver diseases

(2014) Kenji Takahashi et al.   HEPATOLOGY

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

(2014) Julia Kozlitina et al.   NATURE GENETICS

Glucokinase Regulatory Protein Gene Polymorphism Affects Liver Fibrosis in Non-Alcoholic Fatty Liver Disease

(2014) Salvatore Petta et al.   PLoS One

A New lncRNA, APTR, Associates with and Represses the CDKN1A/p21 Promoter by Recruiting Polycomb Proteins

(2014) Masamitsu Negishi et al.   PLoS One

A Pilot Study of Serum MicroRNAs Panel as Potential Biomarkers for Diagnosis of Nonalcoholic Fatty Liver Disease

(2014) Youwen Tan et al.   PLoS One

TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content

(2014) H. Mahdessian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional regulatory functions of nuclear long noncoding RNAs

(2014) Keith W. Vance et al.   TRENDS IN GENETICS

TM6SF2 and MAC30, new enzyme homologs in sterol metabolism and common metabolic disease

(2014) Luis Sanchez-Pulido et al.   Frontiers in Genetics

Impact of sterol regulatory element-binding factor-1c polymorphism on incidence of nonalcoholic fatty liver disease and on the severity of liver disease and of glucose and lipid dysmetabolism

(2013) Giovanni Musso et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Associations between circulating microRNAs (miR-21, miR-34a, miR-122 and miR-451) and non-alcoholic fatty liver

(2013) Hiroya Yamada et al.   CLINICA CHIMICA ACTA

Peroxisome proliferator-activated receptors alpha and gamma2 polymorphisms in nonalcoholic fatty liver disease: A study in Brazilian patients

(2013) Fernanda Aparecida Domenici et al.   GENE

Genomic aspects of NAFLD pathogenesis

(2013) Adviti Naik et al.   GENOMICS

MicroRNA-22 Is a Master Regulator of Bone Morphogenetic Protein-7/6 Homeostasis in the Kidney

(2013) Jianyin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Significance of serum and hepatic microRNA-122 levels in patients with non-alcoholic fatty liver disease

(2013) Hisamitsu Miyaaki et al.   LIVER INTERNATIONAL

Structure and function of long noncoding RNAs in epigenetic regulation

(2013) Tim R Mercer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transcriptional Control of Hepatic Lipid Metabolism by SREBP and ChREBP

(2013) Xu Xu et al.   SEMINARS IN LIVER DISEASE

Integrative transcriptome analysis suggest processing of a subset of long non-coding RNAs to small RNAs

(2012) Saakshi Jalali et al.   Biology Direct

Sterol Regulatory Element-Binding Factor 2 (SREBF-2) Predicts 7-Year NAFLD Incidence and Severity of Liver Disease and Lipoprotein and Glucose Dysmetabolism

(2012) G. Musso et al.   DIABETES

Two genetic variants in FABP1 and susceptibility to non-alcohol fatty liver disease in a Chinese population

(2012) Xian-E Peng et al.   GENE

Posttranscriptional Gene Regulation by Long Noncoding RNA

(2012) Je-Hyun Yoon et al.   JOURNAL OF MOLECULAR BIOLOGY

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

Genetics and epigenetics in the fibrogenic evolution of chronic liver diseases

(2011) Vincent Zimmer et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease

(2011) Silvia Sookoian et al.   HEPATOLOGY

Genetic determinants of hepatic steatosis in man

(2011) Amanda J. Hooper et al.   JOURNAL OF LIPID RESEARCH

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

Circulating MicroRNAs in Patients with Chronic Hepatitis C and Non-Alcoholic Fatty Liver Disease

(2011) Silvia Cermelli et al.   PLoS One

MicroRNAs and liver disease

(2011) Thomas A. Kerr et al.   Translational Research

microRNAs: Fad or future of liver disease

(2011) Ashley M Lakner   WORLD JOURNAL OF GASTROENTEROLOGY

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

(2011) Elizabeth K. Speliotes et al.   PLoS Genetics

Genome-Wide Association Study Identifies Variants Associated With Histologic Features of Nonalcoholic Fatty Liver Disease

(2010) Naga Chalasani et al.   GASTROENTEROLOGY

MicroRNA-370 controls the expression of MicroRNA-122 and Cpt1α and affects lipid metabolism

(2010) Dimitrios Iliopoulos et al.   JOURNAL OF LIPID RESEARCH

Circulating MicroRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis

(2010) Jian Xu et al.   MOLECULAR CARCINOGENESIS

Epigenetic modifications and human disease

(2010) Anna Portela et al.   NATURE BIOTECHNOLOGY

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

(2010) K. J. Rayner et al.   SCIENCE

Increased Expression of Cyclooxygenase-2 is Associated with the Progression to Cirrhosis

(2010) Soung Won Jeong et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

(2009) A. Kotronen et al.   DIABETOLOGIA

miR-221 overexpression contributes to liver tumorigenesis

(2009) P. Pineau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucose Activates ChREBP by Increasing Its Rate of Nuclear Entry and Relieving Repression of Its Transcriptional Activity

(2008) Michael N. Davies et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA