Role of MicroRNAs in NAFLD/NASH

Role of miR-146a in regulation of the acute inflammatory response to monosodium urate crystals

(2015) Nicola Dalbeth et al.   ANNALS OF THE RHEUMATIC DISEASES

A concise review of non-alcoholic fatty liver disease

(2015) Nwe Ni Than et al.   ATHEROSCLEROSIS

miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells

(2015) J. Zhang et al.   CANCER RESEARCH

IL-17 Axis Driven Inflammation in Non-Alcoholic Fatty Liver Disease Progression

(2015) Daniel Giles et al.   CURRENT DRUG TARGETS

MicroRNA regulation of allergic inflammation and asthma

(2015) Heather H Pua et al.   CURRENT OPINION IN IMMUNOLOGY

Obstructive Sleep Apnea Is Associated with Nonalcoholic Steatohepatitis and Advanced Liver Histology

(2015) Kathleen E. Corey et al.   DIGESTIVE DISEASES AND SCIENCES

Downregulation of microRNA-451 in non-alcoholic steatohepatitis inhibits fatty acid-induced proinflammatory cytokine production through the AMPK/AKT pathway

(2015) Wonhee Hur et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice

(2015) Arvin Iracheta-Vellve et al.   JOURNAL OF HEPATOLOGY

miR-122 – A key factor and therapeutic target in liver disease

(2015) Simonetta Bandiera et al.   JOURNAL OF HEPATOLOGY

Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease

(2015) Jan Petrasek et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A Comprehensive Review of Metabolic Syndrome Affecting Erectile Dysfunction

(2015) Ecem Kaya et al.   Journal of Sexual Medicine

Increased number of circulating exosomes and their microRNA cargos are potential novel biomarkers in alcoholic hepatitis

(2015) Fatemeh Momen-Heravi et al.   Journal of Translational Medicine

High Concentrations of Uric Acid Inhibit Endothelial Cell Migration via miR-663 Which Regulates Phosphatase and Tensin Homolog by Targeting Transforming Growth Factor-β1

(2015) Quan Hong et al.   MICROCIRCULATION

MicroRNA regulatory networks in human adipose tissue and obesity

(2015) Peter Arner et al.   Nature Reviews Endocrinology

Inflammasome activation and function in liver disease

(2015) Gyongyi Szabo et al.   Nature Reviews Gastroenterology & Hepatology

Role of the Gut Microbiome in Nonalcoholic Fatty Liver Disease

(2015) Bashar Aqel et al.   NUTRITION IN CLINICAL PRACTICE

Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs

(2015) Eric Londin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs in lung diseases: Recent findings and their pathophysiological implications

(2015) Ammar Ebrahimi et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

The Gut Microbiota and Nonalcoholic Fatty Liver Disease

(2015) Howard Monsour et al.   SEMINARS IN LIVER DISEASE

Polycystic Ovary Syndrome: Important Underrecognised Cardiometabolic Risk Factor in Reproductive-Age Women

(2015) Dinka Pavicic Baldani et al.   International Journal of Endocrinology

Biodistribution and function of extracellular miRNA-155 in mice

(2015) Shashi Bala et al.   Scientific Reports

MiR-146a-5p suppresses activation and proliferation of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis through directly targeting Wnt1 and Wnt5a

(2015) Jinghua Du et al.   Scientific Reports

MicroRNA Processing and Human Cancer

(2015) Masahisa Ohtsuka et al.   Journal of Clinical Medicine

Asthma and metabolic syndrome: Current knowledge and future perspectives

(2015) Laura Serafino-Agrusa   World Journal of Clinical Cases

MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis

(2015) Timea Csak et al.   PLoS One

Micro-RNA-155 Deficiency Prevents Alcohol-Induced Serum Endotoxin Increase and Small Bowel Inflammation in Mice

(2014) Dora Lippai et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

MicroRNAs in liver cancer: a model for investigating pathogenesis and novel therapeutic approaches

(2014) E Callegari et al.   CELL DEATH AND DIFFERENTIATION

Aberrant Hepatic MicroRNA Expression in Nonalcoholic Fatty Liver Disease

(2014) Yue Ying Feng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis

(2014) Carlos J Pirola et al.   GUT

Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia

(2014) Raymond Ng et al.   HEPATOLOGY

Circulating RNA Molecules as Biomarkers in Liver Disease

(2014) Liviu Enache et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Application of microRNAs in diabetes mellitus

(2014) Haiyong Chen et al.   JOURNAL OF ENDOCRINOLOGY

Antitumor function of microRNA-122 against hepatocellular carcinoma

(2014) Kazuhiko Nakao et al.   JOURNAL OF GASTROENTEROLOGY

microRNA-122 regulates hypoxia-inducible factor-1 and vimentin in hepatocytes and correlates with fibrosis in diet-induced steatohepatitis

(2014) Timea Csak et al.   LIVER INTERNATIONAL

MicroRNAs in kidney physiology and disease

(2014) Piera Trionfini et al.   Nature Reviews Nephrology

A Pilot Study of Serum MicroRNAs Panel as Potential Biomarkers for Diagnosis of Nonalcoholic Fatty Liver Disease

(2014) Youwen Tan et al.   PLoS One

MiR-21 Simultaneously Regulates ERK1 Signaling in HSC Activation and Hepatocyte EMT in Hepatic Fibrosis

(2014) Juan Zhao et al.   PLoS One

Micro spies from the brain to the periphery: new clues from studies on microRNAs in neuropsychiatric disorders

(2014) Elisabetta Maffioletti et al.   Frontiers in Cellular Neuroscience

Hepatitis C virus and human miR-122: insights from the bench to the clinic

(2014) Joyce A Wilson et al.   Current Opinion in Virology

MicroRNAs in Nonalcoholic Fatty Liver Disease: Novel Biomarkers and Prognostic Tools during the Transition from Steatosis to Hepatocarcinoma

(2014) Manuele Gori et al.   Biomed Research International

Sleep-disordered breathing, type 2 diabetes and the metabolic syndrome

(2014) Ian W Seetho et al.   Chronic Respiratory Disease

Associations between circulating microRNAs (miR-21, miR-34a, miR-122 and miR-451) and non-alcoholic fatty liver

(2013) Hiroya Yamada et al.   CLINICA CHIMICA ACTA

Sugar, Uric Acid, and the Etiology of Diabetes and Obesity

(2013) R. J. Johnson et al.   DIABETES

Regulation of cholesterol and bile acid homeostasis by the cholesterol 7α-hydroxylase/steroid response element-binding protein 2/microRNA-33a axis in mice

(2013) Tiangang Li et al.   HEPATOLOGY

The Intracellular Sensor NOD2 Induces MicroRNA-29 Expression in Human Dendritic Cells to Limit IL-23 Release

(2013) Oliver Brain et al.   IMMUNITY

Expression of genes for microRNA-processing enzymes is altered in advanced non-alcoholic fatty liver disease

(2013) Haveesh Sharma et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

MicroRNAs in liver disease

(2013) Gyongyi Szabo et al.   Nature Reviews Gastroenterology & Hepatology

MicroRNAs in normal and psoriatic skin

(2013) Jing Xia et al.   PHYSIOLOGICAL GENOMICS

MiR-155 Has a Protective Role in the Development of Non-Alcoholic Hepatosteatosis in Mice

(2013) Ashley M. Miller et al.   PLoS One

MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice

(2013) Takahiro Horie et al.   Nature Communications

Obesity Modulation - The Role in Carcinogenesis

(2012) Ioannis Legakis et al.   Anti-Cancer Agents in Medicinal Chemistry

Differential microRNA response to a high-cholesterol, high-fat diet in livers of low and high LDL-C baboons

(2012) Genesio M Karere et al.   BMC GENOMICS

A Novel Regulator of Macrophage Activation

(2012) Guoqing Zhuang et al.   CIRCULATION

Adipose Tissue MicroRNAs as Regulators of CCL2 Production in Human Obesity

(2012) E. Arner et al.   DIABETES

miR-33 controls the expression of biliary transporters, and mediates statin- and diet-induced hepatotoxicity

(2012) Ryan M. Allen et al.   EMBO Molecular Medicine

MicroRNAs Regulated by Adiponectin as Novel Targets for Controlling Adipose Tissue Inflammation

(2012) Qian Ge et al.   ENDOCRINOLOGY

Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases

(2012) Shashi Bala et al.   HEPATOLOGY

Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy

(2012) Y. Lee et al.   HUMAN MOLECULAR GENETICS

Enhanced Susceptibility to Citrobacter rodentium Infection in MicroRNA-155-Deficient Mice

(2012) Simon Clare et al.   INFECTION AND IMMUNITY

Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver

(2012) Shu-hao Hsu et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis

(2012) Wei-Chih Tsai et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatocellular carcinoma in non-alcoholic fatty liver disease: An emerging menace

(2012) György Baffy et al.   JOURNAL OF HEPATOLOGY

Lycopene inhibits hepatic steatosis via microRNA-21-induced downregulation of fatty acid-binding protein 7 in mice fed a high-fat diet

(2012) Jiyun Ahn et al.   MOLECULAR NUTRITION & FOOD RESEARCH

TGF-β conditions intestinal T cells to express increased levels of miR-155, associated with down-regulation of IL-2 and itk mRNA

(2012) L M Das et al.   Mucosal Immunology

TGF-β and retinoic acid induce the microRNA miR-10a, which targets Bcl-6 and constrains the plasticity of helper T cells

(2012) Hayato Takahashi et al.   NATURE IMMUNOLOGY

Uric acid as a danger signal in gout and its comorbidities

(2012) Kenneth L. Rock et al.   Nature Reviews Rheumatology

Metformin Prevents and Reverses Inflammation in a Non-Diabetic Mouse Model of Nonalcoholic Steatohepatitis

(2012) Yuki Kita et al.   PLoS One

Distinct AGO1 and AGO2 associated miRNA profiles in human cells and blood plasma

(2012) Andrey Turchinovich et al.   RNA Biology

Hyperuricemia as a Mediator of the Proinflammatory Endocrine Imbalance in the Adipose Tissue in a Murine Model of the Metabolic Syndrome

(2011) W. Baldwin et al.   DIABETES

Hepatic angiogenesis and fibrosis are common features in morbidly obese patients

(2011) Monika Ciupińska-Kajor et al.   Hepatology International

Differential miRNA Expression in Omental Adipose Tissue and in the Circulation of Obese Patients Identifies Novel Metabolic Biomarkers

(2011) H. M. Heneghan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Nonalcoholic fatty liver disease is associated with an altered hepatocyte microRNA profile in LDL receptor knockout mice

(2011) Menno Hoekstra et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Epithelial microRNAs regulate gut mucosal immunity via epithelium–T cell crosstalk

(2011) Moshe Biton et al.   NATURE IMMUNOLOGY

Characterization of extracellular circulating microRNA

(2011) Andrey Turchinovich et al.   NUCLEIC ACIDS RESEARCH

Circulating MicroRNAs in Patients with Chronic Hepatitis C and Non-Alcoholic Fatty Liver Disease

(2011) Silvia Cermelli et al.   PLoS One

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential expression of miRNAs in the visceral adipose tissue of patients with non-alcoholic fatty liver disease

(2010) M. Estep et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

The MicroRNA Spectrum in 12 Body Fluids

(2010) J. A. Weber et al.   CLINICAL CHEMISTRY

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Up-regulation of MicroRNA-155 in Macrophages Contributes to Increased Tumor Necrosis Factor α (TNFα) Production via Increased mRNA Half-life in Alcoholic Liver Disease

(2010) Shashi Bala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Pathway Involving Farnesoid X Receptor and Small Heterodimer Partner Positively Regulates Hepatic Sirtuin 1 Levels via MicroRNA-34a Inhibition

(2010) Jiyoung Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

(2010) M. Vijay-Kumar et al.   SCIENCE

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

(2010) S. H. Najafi-Shoushtari et al.   SCIENCE

Obstructive sleep apnea syndrome and fatty liver: Association or causal link?

(2010) Mohamed H Ahmed   WORLD JOURNAL OF GASTROENTEROLOGY

MicroRNA Expression Profile in Lieber-DeCarli Diet-Induced Alcoholic and Methionine Choline Deficient Diet-Induced Nonalcoholic Steatohepatitis Models in Mice

(2009) Angela Dolganiuc et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

The miR-34 family in cancer and apoptosis

(2009) H Hermeking   CELL DEATH AND DIFFERENTIATION

VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice

(2009) Arumugam Velayudham et al.   HEPATOLOGY

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease

(2009) Luca Miele et al.   HEPATOLOGY

Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice

(2009) Bo Wang et al.   HEPATOLOGY

Differential expression of microRNAs in mouse liver under aberrant energy metabolic status

(2009) Shengjie Li et al.   JOURNAL OF LIPID RESEARCH

MicroRNA 132 Regulates Nutritional Stress-Induced Chemokine Production through Repression of SirT1

(2009) Jay C. Strum et al.   MOLECULAR ENDOCRINOLOGY

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

(2008) Xi Chen et al.   CELL RESEARCH

Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression

(2008) Onpan Cheung et al.   HEPATOLOGY

MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation

(2008) Ulf Andersson Ørom et al.   MOLECULAR CELL

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE

miR-34a repression of SIRT1 regulates apoptosis

(2008) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs, the immune system and rheumatic disease

(2008) Esmerina Tili et al.   Nature clinical practice. Rheumatology