Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis

Protein Tyrosine Phosphatase α Mediates Profibrotic Signaling in Lung Fibroblasts through TGF-β Responsiveness

(2014) Yael Aschner et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of NADPH Oxidases in Liver Fibrosis

(2013) Yong-Han Paik et al.   ANTIOXIDANTS & REDOX SIGNALING

3,3′-Diindolylmethane ameliorates experimental hepatic fibrosis via inhibiting miR-21 expression

(2013) Zhengping Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Obesity-Associated Nonalcoholic Fatty Liver Disease

(2013) Yusuf Yilmaz et al.   Clinics in Liver Disease

Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice

(2013) Ling Yang et al.   HEPATOLOGY

Transforming Growth Factor-β (TGF-β)-mediated Connective Tissue Growth Factor (CTGF) Expression in Hepatic Stellate Cells Requires Stat3 Signaling Activation

(2013) Yan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-alcoholic steatohepatitis: Pathogenesis and novel therapeutic approaches

(2013) Detlef Schuppan et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

NAFLD, NASH and liver cancer

(2013) Gregory A. Michelotti et al.   Nature Reviews Gastroenterology & Hepatology

Environmental Toxin–Linked Nonalcoholic Steatohepatitis and Hepatic Metabolic Reprogramming in Obese Mice

(2013) Ratanesh Kumar Seth et al.   TOXICOLOGICAL SCIENCES

CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis

(2013) Ratanesh Kumar Seth et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

MicroRNAs and fibrosis

(2012) Vishal Patel et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis

(2012) Saurabh Chatterjee et al.   JOURNAL OF HEPATOLOGY

Smad7 suppresses renal fibrosis via altering expression of TGF-β/Smad3-regulated microRNAs

(2012) Arthur C.K. Chung et al.   MOLECULAR THERAPY

microRNA are Central Players in Anti- and Profibrotic Gene Regulation during Liver Fibrosis

(2012) Andrea Noetel et al.   Frontiers in Physiology

TGF-β in progression of liver disease

(2011) Steven Dooley et al.   CELL AND TISSUE RESEARCH

A trio of microRNAs that control Toll-like receptor signalling

(2011) S. R. Quinn et al.   INTERNATIONAL IMMUNOLOGY

The microRNA-21-PDCD4 axis prevents type 1 diabetes by blocking pancreatic   cell death

(2011) Q. Ruan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibrogenesis in nonalcoholic steatohepatitis

(2011) Samuele De Minicis et al.   Expert Review of Gastroenterology & Hepatology

Leptin: The Prototypic Adipocytokine and its Role in NAFLD

(2010) Claudio Procaccini et al.   CURRENT PHARMACEUTICAL DESIGN

Role of microRNAs in Non-Alcoholic Steatohepatitis

(2010) Onpan Cheung et al.   CURRENT PHARMACEUTICAL DESIGN

EDA-containing cellular fibronectin induces fibroblast differentiation through binding to α4β7 integrin receptor and MAPK/Erk 1/2-dependent signaling

(2010) Martin Kohan et al.   FASEB JOURNAL

Leptin Promotes the Myofibroblastic Phenotype in Hepatic Stellate Cells by Activating the Hedgehog Pathway

(2010) Steve S. Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

(2010) Gang Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Increased Soluble Leptin Receptor Levels in Morbidly Obese Patients With Insulin Resistance and Nonalcoholic Fatty Liver Disease

(2010) Valentina Medici et al.   Obesity

Kupffer Cells Mediate Leptin-Induced Liver Fibrosis

(2009) Jianhua Wang et al.   GASTROENTEROLOGY

Involvement of MicroRNAs in Hydrogen Peroxide-mediated Gene Regulation and Cellular Injury Response in Vascular Smooth Muscle Cells

(2009) Ying Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

(2009) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells

(2008) Samuele De Minicis et al.   HEPATOLOGY

Adipocytokines and liver disease

(2008) Yoshihiro Kamada et al.   JOURNAL OF GASTROENTEROLOGY