Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease

Pervasive supply of therapeutic lysosomal enzymes in the CNS of normal and Krabbe‐affected non‐human primates by intracerebral lentiviral gene therapy

(2016) Vasco Meneghini et al.   EMBO Molecular Medicine

RP-CARS reveals molecular spatial order anomalies in myelin of an animal model of Krabbe disease

(2016) Giuseppe de Vito et al.   Journal of Biophotonics

Altered Trafficking and Processing of GALC Mutants Correlates with Globoid Cell Leukodystrophy Severity

(2016) D. Shin et al.   JOURNAL OF NEUROSCIENCE

Endothelial cell dysfunction in globoid cell leukodystrophy

(2016) Mirella Belleri et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis

(2016) Giovanni Manfredi et al.   NEUROBIOLOGY OF DISEASE

History, genetic, and recent advances on Krabbe disease

(2015) Adriana Carol Eleonora Graziano et al.   GENE

Combined gene/cell therapies provide long-term and pervasive rescue of multiple pathological symptoms in a murine model of globoid cell leukodystrophy

(2015) A. Ricca et al.   HUMAN MOLECULAR GENETICS

Mechanism of Neuromuscular Dysfunction in Krabbe Disease

(2015) L. Cantuti-Castelvetri et al.   JOURNAL OF NEUROSCIENCE

Mechanism-Based Combination Treatment Dramatically Increases Therapeutic Efficacy in Murine Globoid Cell Leukodystrophy

(2015) J. A. Hawkins-Salsbury et al.   JOURNAL OF NEUROSCIENCE

Long-term Improvements in Lifespan and Pathology in CNS and PNS After BMT Plus One Intravenous Injection of AAVrh10-GALC in Twitcher Mice

(2015) Mohammad A Rafi et al.   MOLECULAR THERAPY

Pharmacological chaperones increase residual β-galactocerebrosidase activity in fibroblasts from Krabbe patients

(2014) Anna Sara Berardi et al.   MOLECULAR GENETICS AND METABOLISM

Early axonal loss accompanied by impaired endocytosis, abnormal axonal transport, and decreased microtubule stability occur in the model of Krabbe's disease

(2014) Carla Andreia Teixeira et al.   NEUROBIOLOGY OF DISEASE

Role of extracellular calcium and mitochondrial oxygen species in psychosine-induced oligodendrocyte cell death

(2014) V Voccoli et al.   Cell Death & Disease

Deficient nitric oxide signalling impairs skeletal muscle growth and performance: involvement of mitochondrial dysregulation

(2014) Clara De Palma et al.   Skeletal Muscle

Inhibition of angiogenesis by β-galactosylceramidase deficiency in globoid cell leukodystrophy

(2013) Mirella Belleri et al.   BRAIN

Region- and Age-Dependent Alterations of Glial-Neuronal Metabolic Interactions Correlate with CNS Pathology in a Mouse Model of Globoid Cell Leukodystrophy

(2013) Tore Wergeland Meisingset et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Sphingolipid Psychosine Inhibits Fast Axonal Transport in Krabbe Disease by Activation of GSK3  and Deregulation of Molecular Motors

(2013) L. Cantuti Castelvetri et al.   JOURNAL OF NEUROSCIENCE

Oxidative stress as a therapeutic target in globoid cell leukodystrophy

(2012) Jacqueline A. Hawkins-Salsbury et al.   EXPERIMENTAL NEUROLOGY

Analysis of neuromuscular junctions and effects of anabolic steroid administration in the SOD1G93A mouse model of ALS

(2012) Valentina Cappello et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A role for Schwann cell–derived neuregulin-1 in remyelination

(2012) Ruth M Stassart et al.   NATURE NEUROSCIENCE

Psychosine induces the dephosphorylation of neurofilaments by deregulation of PP1 and PP2A phosphatases

(2012) Ludovico Cantuti-Castelvetri et al.   NEUROBIOLOGY OF DISEASE

Axonopathy is a compounding factor in the pathogenesis of Krabbe disease

(2011) Ludovico Cantuti Castelvetri et al.   ACTA NEUROPATHOLOGICA

Peripheral Neuropathy in the Twitcher Mouse Involves the Activation of Axonal Caspase 3

(2011) Benjamin Smith et al.   ASN Neuro

The Myelin Mutants as Models to Study Myelin Repair in the Leukodystrophies

(2011) Ian D. Duncan et al.   Neurotherapeutics

SMN Requirement for Synaptic Vesicle, Active Zone and Microtubule Postnatal Organization in Motor Nerve Terminals

(2011) Laura Torres-Benito et al.   PLoS One

The short-time structural plasticity of dendritic spines is altered in a model of Rett syndrome

(2011) Silvia Landi et al.   Scientific Reports

Motor Neuron Diversity in Development and Disease

(2010) Kevin C. Kanning et al.   Annual Review of Neuroscience

Sustained Axon-Glial Signaling Induces Schwann Cell Hyperproliferation, Remak Bundle Myelination, and Tumorigenesis

(2009) J. A. Gomez-Sanchez et al.   JOURNAL OF NEUROSCIENCE

Psychosine Accumulates in Membrane Microdomains in the Brain of Krabbe Patients, Disrupting the Raft Architecture

(2009) A. B. White et al.   JOURNAL OF NEUROSCIENCE

Biology and pathology of nonmyelinating Schwann cells

(2008) John W. Griffin et al.   GLIA

Negative regulation of myelination: Relevance for development, injury, and demyelinating disease

(2008) Kristján R. Jessen et al.   GLIA