- Home
- Publications
- Publication Search
- Publication Details
Title
Drug development in targeting ion channels for brain edema
Authors
Keywords
-
Journal
ACTA PHARMACOLOGICA SINICA
Volume 41, Issue 10, Pages 1272-1288
Publisher
Springer Science and Business Media LLC
Online
2020-08-27
DOI
10.1038/s41401-020-00503-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cerebrospinal fluid influx drives acute ischemic tissue swelling
- (2020) Humberto Mestre et al. SCIENCE
- Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema
- (2020) Philip Kitchen et al. CELL
- Glutamate-Releasing SWELL1 Channel in Astrocytes Modulates Synaptic Transmission and Promotes Brain Damage in Stroke
- (2019) Junhua Yang et al. NEURON
- Functionalized Phenylbenzamides Inhibit Aquaporin-4 Reducing Cerebral Edema and Improving Outcome in Two Models of CNS Injury
- (2019) George W. Farr et al. NEUROSCIENCE
- A Novel Na + -K + -Cl − Cotransporter 1 Inhibitor STS66* Reduces Brain Damage in Mice After Ischemic Stroke
- (2019) Huachen Huang et al. STROKE
- Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs
- (2019) David M Kern et al. eLife
- Structure and mechanism of the cation–chloride cotransporter NKCC1
- (2019) Thomas A. Chew et al. NATURE
- TMEM16A Inhibition Preserves Blood–Brain Barrier Integrity After Ischemic Stroke
- (2019) Pin-yi Liu et al. Frontiers in Cellular Neuroscience
- Elevated blood glucose is associated with aggravated brain edema in acute stroke
- (2019) Gabriel Broocks et al. JOURNAL OF NEUROLOGY
- SUR1-TRPM4 channels, not KATP, mediate brain swelling following cerebral ischemia
- (2019) Seung Kyoon Woo et al. NEUROSCIENCE LETTERS
- Blockade of the swelling-induced chloride current attenuates the mouse neonatal hypoxic-ischemic brain injury in vivo
- (2018) Raymond Wong et al. ACTA PHARMACOLOGICA SINICA
- CFTR prevents neuronal apoptosis following cerebral ischemia reperfusion via regulating mitochondrial oxidative stress
- (2018) Ya-Ping Zhang et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- RS1 (Rsc1A1) deficiency limits cerebral SGLT1 expression and delays brain damage after experimental traumatic brain injury
- (2018) Anne Sebastiani et al. JOURNAL OF NEUROCHEMISTRY
- Operation Brain Trauma Therapy: 2016 Update
- (2018) Patrick M Kochanek et al. MILITARY MEDICINE
- KCC2, epileptiform synchronization, and epileptic disorders
- (2018) Graziella Di Cristo et al. PROGRESS IN NEUROBIOLOGY
- Long-Term Outcomes in Patients Aged ≤70 Years With Intravenous Glyburide From the Phase II GAMES-RP Study of Large Hemispheric Infarction
- (2018) Kevin N. Sheth et al. STROKE
- Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium-potassium-chloride-cotransporter human variants hNKCC1A and hNKCC1B
- (2018) Philip Hampel et al. Scientific Reports
- Validation of sodium/glucose cotransporter proteins in human brain as a potential marker for temporal narrowing of the trauma formation
- (2018) Sabrina Oerter et al. INTERNATIONAL JOURNAL OF LEGAL MEDICINE
- Structure of a volume-regulated anion channel of the LRRC8 family
- (2018) Dawid Deneka et al. NATURE
- Pathophysiology and treatment of cerebral edema in traumatic brain injury
- (2018) Ruchira M. Jha et al. NEUROPHARMACOLOGY
- Recent advances in TMEM16A: Structure, function, and disease
- (2018) Qiushuang Ji et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Neurons rely on glucose rather than astrocytic lactate during stimulation
- (2018) Carlos Manlio Díaz-García et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Selective knockout of astrocytic Na+ /H+ exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke
- (2017) Gulnaz Begum et al. GLIA
- SUR1-TRPM4 and AQP4 form a heteromultimeric complex that amplifies ion/water osmotic coupling and drives astrocyte swelling
- (2017) Jesse A. Stokum et al. GLIA
- Inhibition of Aquaporin-4 Improves the Outcome of Ischaemic Stroke and Modulates Brain Paravascular Drainage Pathways
- (2017) Ionica Pirici et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Transient receptor potential vanilloid type 4 channels mediate Na-K-Cl-co-transporter-induced brain edema after traumatic brain injury
- (2017) Kwok-Tung Lu et al. JOURNAL OF NEUROCHEMISTRY
- Cryo-EM structures of the TMEM16A calcium-activated chloride channel
- (2017) Shangyu Dang et al. NATURE
- Predictors for Cerebral Edema in Acute Ischemic Stroke Treated With Intravenous Thrombolysis
- (2017) Magnus Thorén et al. STROKE
- Chloride Dysregulation, Seizures, and Cerebral Edema: A Relationship with Therapeutic Potential
- (2017) Joseph Glykys et al. TRENDS IN NEUROSCIENCES
- Sodium Tanshinone IIA Sulfonate Enhances Effectiveness Rt-PA Treatment in Acute Ischemic Stroke Patients Associated with Ameliorating Blood-Brain Barrier Damage
- (2017) Biying Ji et al. Translational Stroke Research
- Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A
- (2017) Cristina Paulino et al. eLife
- Comparative Effects of Chloride Channel Inhibitors on LRRC8/VRAC-Mediated Chloride Conductance
- (2017) Jonas Friard et al. Frontiers in Pharmacology
- ClC Channels and Transporters: Structure, Physiological Functions, and Implications in Human Chloride Channelopathies
- (2017) Diogo R. Poroca et al. Frontiers in Pharmacology
- LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
- (2016) Ruhma Syeda et al. CELL
- CFTR pharmacology
- (2016) Olga Zegarra-Moran et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Cerebrovascular Safety of Sulfonylureas: The Role of KATPChannels in Neuroprotection and the Risk of Stroke in Patients With Type 2 Diabetes
- (2016) Rui Liu et al. DIABETES
- The bumetanide prodrug BUM5, but not bumetanide, potentiates the antiseizure effect of phenobarbital in adult epileptic mice
- (2016) Thomas Erker et al. EPILEPSIA
- Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt
- (2016) Pasquale Molinaro et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Improved long-term outcome after transient cerebral ischemia in aquaporin-4 knockout mice
- (2016) Lorenz Hirt et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Transient Oxygen/Glucose Deprivation Causes a Delayed Loss of Mitochondria and Increases Spontaneous Calcium Signaling in Astrocytic Processes
- (2016) J. C. O'Donnell et al. JOURNAL OF NEUROSCIENCE
- Melatonin attenuates neuronal apoptosis through up-regulation of K+-Cl−cotransporter KCC2 expression following traumatic brain injury in rats
- (2016) Haijian Wu et al. JOURNAL OF PINEAL RESEARCH
- Safety and efficacy of intravenous glyburide on brain swelling after large hemispheric infarction (GAMES-RP): a randomised, double-blind, placebo-controlled phase 2 trial
- (2016) Kevin N Sheth et al. LANCET NEUROLOGY
- ABCC8 Single Nucleotide Polymorphisms are Associated with Cerebral Edema in Severe TBI
- (2016) Ruchira M. Jha et al. Neurocritical Care
- GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters
- (2016) Dong Deng et al. PROTEIN SCIENCE
- Structural Features of Ion Transport and Allosteric Regulation in Sodium-Calcium Exchanger (NCX) Proteins
- (2016) Moshe Giladi et al. Frontiers in Physiology
- New selective inhibitors of calcium-activated chloride channels - T16Ainh-A01, CaCCinh-A01 and MONNA - what do they inhibit?
- (2015) D M B Boedtkjer et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Cellular Mechanisms of Neuronal Swelling Underlying Cytotoxic Edema
- (2015) Ravi L. Rungta et al. CELL
- Role of volume-regulated and calcium-activated anion channels in cell volume homeostasis, cancer and drug resistance
- (2015) Else K Hoffmann et al. Channels
- 23
- (2015) Jessica Wallisch et al. CRITICAL CARE MEDICINE
- Glutamate and GABA Imbalance Following Traumatic Brain Injury
- (2015) Réjean M. Guerriero et al. Current Neurology and Neuroscience Reports
- Neuronal KATP channels mediate hypoxic preconditioning and reduce subsequent neonatal hypoxic–ischemic brain injury
- (2015) Hong-Shuo Sun et al. EXPERIMENTAL NEUROLOGY
- Molecular pathophysiology of cerebral edema
- (2015) Jesse A Stokum et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Selective Inhibition of KCC2 Leads to Hyperexcitability and Epileptiform Discharges in Hippocampal Slices and In Vivo
- (2015) S. Sivakumaran et al. JOURNAL OF NEUROSCIENCE
- Mildly Reduced Brain Swelling and Improved Neurological Outcome in Aquaporin-4 Knockout Mice following Controlled Cortical Impact Brain Injury
- (2015) Xiaoming Yao et al. JOURNAL OF NEUROTRAUMA
- PcTx1 affords neuroprotection in a conscious model of stroke in hypertensive rats via selective inhibition of ASIC1a
- (2015) Claudia A. McCarthy et al. NEUROPHARMACOLOGY
- Reduced brain edema and infarct volume in aquaporin-4 deficient mice after transient focal cerebral ischemia
- (2015) Xiaoming Yao et al. NEUROSCIENCE LETTERS
- Deletion of aquaporin-4 is neuroprotective during the acute stage of micro traumatic brain injury in mice
- (2015) Fengyin Liang et al. NEUROSCIENCE LETTERS
- Volume-regulated anion channel—a frenemy within the brain
- (2015) Alexander A. Mongin PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Imaging of a Clinically Relevant Stroke Model
- (2015) Fabian Arnberg et al. STROKE
- The Role of Na+/Ca2+ Exchanger Subtypes in Neuronal Ischemic Injury
- (2015) Botros Shenoda Translational Stroke Research
- Two-dimensional crystal structure of aquaporin-4 bound to the inhibitor acetazolamide
- (2015) Akiko Kamegawa et al. Microscopy
- Heterogeneity of aquaporin-4 localization and expression after focal cerebral ischemia underlies differences in white versus grey matter swelling
- (2015) Jesse A. Stokum et al. Acta Neuropathologica Communications
- A novel prodrug-based strategy to increase effects of bumetanide in epilepsy
- (2014) Kathrin Töllner et al. ANNALS OF NEUROLOGY
- Selective vasopressin-1a receptor antagonist prevents brain edema, reduces astrocytic cell swelling and GFAP, V1aR and AQP4 expression after focal traumatic brain injury
- (2014) Christina R. Marmarou et al. BRAIN RESEARCH
- Hypoxia augments the calcium-activated chloride current carried by anoctamin-1 in cardiac vascular endothelial cells of neonatal mice
- (2014) Ming-Ming Wu et al. BRITISH JOURNAL OF PHARMACOLOGY
- SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
- (2014) Zhaozhu Qiu et al. CELL
- Small Molecule-facilitated Degradation of ANO1 Protein
- (2014) Anke Bill et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Changes and effects of plasma arginine vasopressin in traumatic brain injury
- (2014) W. D. Huang et al. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
- X-ray structure of a calcium-activated TMEM16 lipid scramblase
- (2014) Janine D. Brunner et al. NATURE
- Glibenclamide reduces secondary brain damage after experimental traumatic brain injury
- (2014) K. Zweckberger et al. NEUROSCIENCE
- Neuroprotective effect of aquaporin-4 deficiency in a mouse model of severe global cerebral ischemia produced by transient 4-vessel occlusion
- (2014) Gökhan Akdemir et al. NEUROSCIENCE LETTERS
- Proton-sensitive cation channels and ion exchangers in ischemic brain injury: New therapeutic targets for stroke?
- (2014) Tiandong Leng et al. PROGRESS IN NEUROBIOLOGY
- Identification of LRRC8 Heteromers as an Essential Component of the Volume-Regulated Anion Channel VRAC
- (2014) F. K. Voss et al. SCIENCE
- Drowning stars: reassessing the role of astrocytes in brain edema
- (2014) Alexander S. Thrane et al. TRENDS IN NEUROSCIENCES
- Posttraumatic Reduction of Edema with Aquaporin-4 RNA Interference Improves Acute and Chronic Functional Recovery
- (2013) Andrew M Fukuda et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Brain white matter oedema due to ClC-2 chloride channel deficiency: an observational analytical study
- (2013) Christel Depienne et al. LANCET NEUROLOGY
- Glyburide is Associated with Attenuated Vasogenic Edema in Stroke Patients
- (2013) W. Taylor Kimberly et al. Neurocritical Care
- Loss of Acid Sensing Ion Channel-1a and Bicarbonate Administration Attenuate the Severity of Traumatic Brain Injury
- (2013) Terry Yin et al. PLoS One
- Chloride transport-driven alveolar fluid secretion is a major contributor to cardiogenic lung edema
- (2013) E. A. Solymosi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Excitotoxicity and stroke: Identifying novel targets for neuroprotection
- (2013) Ted Weita Lai et al. PROGRESS IN NEUROBIOLOGY
- Spatiotemporal Uptake Characteristics of [18]F-2-Fluoro-2-Deoxy-D-Glucose in a Rat Middle Cerebral Artery Occlusion Model
- (2013) H. Yuan et al. STROKE
- Modulation of neuronal activity by phosphorylation of the K–Cl cotransporter KCC2
- (2013) Kristopher T. Kahle et al. TRENDS IN NEUROSCIENCES
- Chloride channels in stroke
- (2012) Ya-ping Zhang et al. ACTA PHARMACOLOGICA SINICA
- Structure and activity of the acid-sensing ion channels
- (2012) Thomas W. Sherwood et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Regional distribution of SGLT activity in rat brain in vivo
- (2012) Amy S. Yu et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Plasmalemmal Na+/Ca2+ Exchanger Modulates Ca2+-Dependent Exocytotic Release of Glutamate from Rat Cortical Astrocytes
- (2012) Reno C Reyes et al. ASN Neuro
- Further optimization of the K-Cl cotransporter KCC2 antagonist ML077: Development of a highly selective and more potent in vitro probe
- (2012) Eric Delpire et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- KCC2a Expression in a Human Fetal Lens Epithelial Cell Line
- (2012) Peter K. Lauf et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Loss of astrocyte polarization upon transient focal brain ischemia as a possible mechanism to counteract early edema formation
- (2012) Esther Steiner et al. GLIA
- Intravenous HOE-642 Reduces Brain Edema and Na Uptake in the Rat Permanent Middle Cerebral Artery Occlusion Model of Stroke: Evidence for Participation of the Blood–Brain Barrier Na/H Exchanger
- (2012) Martha E O'Donnell et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Sulfonylurea Receptor 1 in Central Nervous System Injury: A Focused Review
- (2012) J Marc Simard et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Activity-Dependent Cleavage of the K-Cl Cotransporter KCC2 Mediated by Calcium-Activated Protease Calpain
- (2012) M. Puskarjov et al. JOURNAL OF NEUROSCIENCE
- Aquaporin 4 and neuromyelitis optica
- (2012) Marios C Papadopoulos et al. LANCET NEUROLOGY
- Aquaporin-4 distribution in control and stressed astrocytes in culture and in the cerebrospinal fluid of patients with traumatic brain injuries
- (2012) Marianna Lo Pizzo et al. NEUROLOGICAL SCIENCES
- Cation-chloride cotransporters NKCC1 and KCC2 as potential targets for novel antiepileptic and antiepileptogenic treatments
- (2012) Wolfgang Löscher et al. NEUROPHARMACOLOGY
- Aquaporin-4 Deficiency Impairs Synaptic Plasticity and Associative Fear Memory in the Lateral Amygdala: Involvement of Downregulation of Glutamate Transporter-1 Expression
- (2012) Yan-Kun Li et al. NEUROPSYCHOPHARMACOLOGY
- Delayed increase of astrocytic aquaporin 4 after juvenile traumatic brain injury: Possible role in edema resolution?
- (2012) A.M. Fukuda et al. NEUROSCIENCE
- Aggravated chronic brain injury after focal cerebral ischemia in aquaporin-4-deficient mice
- (2012) Wen-Zhen Shi et al. NEUROSCIENCE LETTERS
- ClC-3 chloride channel prevents apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells through mitochondria dependent pathway
- (2011) Yan Qian et al. APOPTOSIS
- Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation
- (2011) Akinobu Suzuki et al. CELL
- TNF-alpha induced NFκB signaling and p65 (RelA) overexpression repress Cldn5 promoter in mouse brain endothelial cells
- (2011) Muhammad Aslam et al. CYTOKINE
- Anoctamin 2/TMEM16B: a calcium-activated chloride channel in olfactory transduction
- (2011) Simone Pifferi et al. EXPERIMENTAL PHYSIOLOGY
- Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice
- (2011) Xiao Su et al. INFLAMMATION RESEARCH
- Potent, Metabolically Stable Benzopyrimido-pyrrolo-oxazine-dione (BPO) CFTR Inhibitors for Polycystic Kidney Disease
- (2011) David S. Snyder et al. JOURNAL OF MEDICINAL CHEMISTRY
- Heteromeric Acid-Sensing Ion Channels (ASICs) Composed of ASIC2b and ASIC1a Display Novel Channel Properties and Contribute to Acidosis-Induced Neuronal Death
- (2011) T. W. Sherwood et al. JOURNAL OF NEUROSCIENCE
- Extracellular Spermine Exacerbates Ischemic Neuronal Injury through Sensitization of ASIC1a Channels to Extracellular Acidosis
- (2011) B. Duan et al. JOURNAL OF NEUROSCIENCE
- The potassium-chloride cotransporter 2 promotes cervical cancer cell migration and invasion by an ion transport-independent mechanism
- (2011) Wei-Chun Wei et al. JOURNAL OF PHYSIOLOGY-LONDON
- Knocking down of the KCC2 in rat hippocampal neurons increases intracellular chloride concentration and compromises neuronal survival
- (2011) Christophe Pellegrino et al. JOURNAL OF PHYSIOLOGY-LONDON
- NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor–mediated currents
- (2011) Henry H C Lee et al. NATURE NEUROSCIENCE
- Emerging mechanisms of disrupted cellular signaling in brain ischemia
- (2011) Michael Tymianski NATURE NEUROSCIENCE
- Volume Regulated Anion Channel Currents of Rat Hippocampal Neurons and Their Contribution to Oxygen-and-Glucose Deprivation Induced Neuronal Death
- (2011) Huaqiu Zhang et al. PLoS One
- Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop
- (2011) Q. Xiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypertonic Saline and Mannitol Therapy in Critical Care Neurology
- (2011) Holly E. Hinson et al. JOURNAL OF INTENSIVE CARE MEDICINE
- Functional expression of SGLTs in rat brain
- (2010) Amy S. Yu et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Altered Expression of Regulators of the Cortical Chloride Transporters NKCC1 and KCC2 in Schizophrenia
- (2010) Dominique Arion et al. ARCHIVES OF GENERAL PSYCHIATRY
- Mechanisms of cerebral edema in traumatic brain injury: therapeutic developments
- (2010) James J Donkin et al. CURRENT OPINION IN NEUROLOGY
- Glibenclamide Reduces Hippocampal Injury and Preserves Rapid Spatial Learning in a Model of Traumatic Brain Injury
- (2010) Ashish D. Patel et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Na+–K+–2Cl− Cotransport Inhibitor Attenuates Cerebral Edema Following Experimental Stroke via the Perivascular Pool of Aquaporin-4
- (2010) Elton R. Migliati et al. Neurocritical Care
- Pretreatment with a novel aquaporin 4 inhibitor, TGN-020, significantly reduces ischemic cerebral edema
- (2010) Hironaka Igarashi et al. NEUROLOGICAL SCIENCES
- Acid-Sensing Ion Channels (ASICs): Pharmacology and implication in pain
- (2010) Emmanuel Deval et al. PHARMACOLOGY & THERAPEUTICS
- Downregulation of Potassium Chloride Cotransporter KCC2 After Transient Focal Cerebral Ischemia
- (2010) Nadine Jaenisch et al. STROKE
- TMEM16 Proteins Produce Volume-regulated Chloride Currents That Are Reduced in Mice Lacking TMEM16A
- (2009) Joana Almaça et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Protein Kinase C Activator Phorbol Myristate Acetate Decreases Brain Edema by Aquaporin 4 Downregulation after Middle Cerebral Artery Occlusion in the Rat
- (2009) Giovanna Fazzina et al. JOURNAL OF NEUROTRAUMA
- Neurologic complications following lung transplantation
- (2009) Saša A. Živković et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Inhibition of Aquaporin-1 and Aquaporin-4 Water Permeability by a Derivative of the Loop Diuretic Bumetanide Acting at an Internal Pore-Occluding Binding Site
- (2009) E. Migliati et al. MOLECULAR PHARMACOLOGY
- Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia
- (2009) Hong-Shuo Sun et al. NATURE NEUROSCIENCE
- VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer
- (2009) Elizabeth R. Gerstner et al. Nature Reviews Clinical Oncology
- Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides
- (2008) Baoxue Yang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Identification of Aquaporin 4 inhibitors using in vitro and in silico methods
- (2008) Vincent J. Huber et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit
- (2008) Björn Christian Schroeder et al. CELL
- Involvement of cystic fibrosis transmembrane conductance regulator in infection-induced edema
- (2008) L AJONUMA et al. CELL BIOLOGY INTERNATIONAL
- DCPIB, a specific inhibitor of volume regulated anion channels (VRACs), reduces infarct size in MCAo and the release of glutamate in the ischemic cortical penumbra
- (2008) Yonghua Zhang et al. EXPERIMENTAL NEUROLOGY
- Posttraumatic GABAA-Mediated [Ca2+]i Increase Is Essential for the Induction of Brain-Derived Neurotrophic Factor-Dependent Survival of Mature Central Neurons
- (2008) A. Shulga et al. JOURNAL OF NEUROSCIENCE
- Targeted Disruption of Na+/Ca2+ Exchanger 3 (NCX3) Gene Leads to a Worsening of Ischemic Brain Damage
- (2008) P. Molinaro et al. JOURNAL OF NEUROSCIENCE
- Differential Hippocampal Protection when Blocking Intracellular Sodium and Calcium Entry during Traumatic Brain Injury in Rats
- (2008) Xueren Zhao et al. JOURNAL OF NEUROTRAUMA
- A Functional Role for Sodium-Dependent Glucose Transport across the Blood-Brain Barrier during Oxygen Glucose Deprivation
- (2008) S. Vemula et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Acetazolamide reversibly inhibits water conduction by aquaporin-4
- (2008) Yukihiro Tanimura et al. JOURNAL OF STRUCTURAL BIOLOGY
- TMEM16A confers receptor-activated calcium-dependent chloride conductance
- (2008) Young Duk Yang et al. NATURE
- SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator
- (2008) J. Aittoniemi et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity
- (2008) A. Caputo et al. SCIENCE
- Activation of Pannexin-1 Hemichannels Augments Aberrant Bursting in the Hippocampus
- (2008) R. J. Thompson et al. SCIENCE
- Protective Effect of Delayed Treatment With Low-Dose Glibenclamide in Three Models of Ischemic Stroke
- (2008) J. Marc Simard et al. STROKE
- Beyond NMDA and AMPA glutamate receptors: emerging mechanisms for ionic imbalance and cell death in stroke
- (2008) Elaine Besancon et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Roles of the cation–chloride cotransporters in neurological disease
- (2008) Kristopher T Kahle et al. Nature clinical practice. Neurology
- Na+/Ca2+ exchanger 2 is neuroprotective by exporting Ca2+ during a transient focal cerebral ischemia in the mouse
- (2007) Daejong Jeon et al. CELL CALCIUM
- Aquaporin-4 independent Kir4.1 K+ channel function in brain glial cells
- (2007) Hua Zhang et al. MOLECULAR AND CELLULAR NEUROSCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now