Neurons rely on glucose rather than astrocytic lactate during stimulation

Fueling thought: Management of glycolysis and oxidative phosphorylation in neuronal metabolism

(2018) Gary Yellen   JOURNAL OF CELL BIOLOGY

CrossTalk proposal: an important astrocyte-to-neuron lactate shuttle couples neuronal activity to glucose utilisation in the brain

(2018) L. F. Barros et al.   JOURNAL OF PHYSIOLOGY-LONDON

Lactate in the brain: from metabolic end-product to signalling molecule

(2018) Pierre J. Magistretti et al.   NATURE REVIEWS NEUROSCIENCE

Neuronal control of astrocytic respiration through a variant of the Crabtree effect

(2018) Ignacio Fernández-Moncada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oligodendrocytes in the Mouse Corpus Callosum Maintain Axonal Function by Delivery of Glucose

(2018) Niklas Meyer et al.   Cell Reports

NBCe1 mediates the regulation of the NADH/NAD+ redox state in cortical astrocytes by neuronal signals

(2018) Susanne Köhler et al.   GLIA

Glycolysis Paradigm Shift Dictates a Reevaluation of Glucose and Oxygen Metabolic Rates of Activated Neural Tissue

(2018) Avital Schurr   Frontiers in Neuroscience

Tight coupling of astrocyte energy metabolism to synaptic activity revealed by genetically encoded FRET nanosensors in hippocampal tissue

(2017) Iván Ruminot et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Evaluating the gray and white matter energy budgets of human brain function

(2017) Yuguo Yu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Glucose feeds the TCA cycle via circulating lactate

(2017) Sheng Hui et al.   NATURE

Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye

(2017) Mark A Kanow et al.   eLife

Monitoring ATP dynamics in electrically active white matter tracts

(2017) Andrea Trevisiol et al.   eLife

Neuronal Culture Microenvironments Determine Preferences in Bioenergetic Pathway Use

(2017) Juliane Sünwoldt et al.   Frontiers in Molecular Neuroscience

A neuronal MCT2 knockdown in the rat somatosensory cortex reduces both the NMR lactate signal and the BOLD response during whisker stimulation

(2017) Leslie Mazuel et al.   PLoS One

Cytosolic NADH-NAD+ Redox Visualized in Brain Slices by Two-Photon Fluorescence Lifetime Biosensor Imaging

(2016) Rebecca Mongeon et al.   ANTIOXIDANTS & REDOX SIGNALING

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons

(2016) Philipp Mächler et al.   Cell Metabolism

Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism

(2016) Aiman S. Saab et al.   NEURON

Neurometabolic coupling between neural activity, glucose, and lactate in activated visual cortex

(2015) Baowang Li et al.   JOURNAL OF NEUROCHEMISTRY

Glucose, lactate, and shuttling of metabolites in vertebrate retinas

(2015) James B. Hurley et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Monitoring Mitochondrial Pyruvate Carrier Activity in Real Time Using a BRET-Based Biosensor: Investigation of the Warburg Effect

(2015) Vincent Compan et al.   MOLECULAR CELL

Pyruvate kinase and aspartate-glutamate carrier distributions reveal key metabolic links between neurons and glia in retina

(2014) K. J. Lindsay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluxes of lactate into, from, and among gap junction-coupled astrocytes and their interaction with noradrenaline

(2014) Leif Hertz et al.   Frontiers in Neuroscience

Glutamatergic Function in the Resting Awake Human Brain is Supported by Uniformly High Oxidative Energy

(2013) Fahmeed Hyder et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Oxidative Phosphorylation, Not Glycolysis, Powers Presynaptic and Postsynaptic Mechanisms Underlying Brain Information Processing

(2012) C. N. Hall et al.   JOURNAL OF NEUROSCIENCE

Imaging Cytosolic NADH-NAD+ Redox State with a Genetically Encoded Fluorescent Biosensor

(2011) Yin Pun Hung et al.   Cell Metabolism

Brain Lactate Metabolism: The Discoveries and the Controversies

(2011) Gerald A Dienel   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

In Vivo Evidence for Lactate as a Neuronal Energy Source

(2011) M. T. Wyss et al.   JOURNAL OF NEUROSCIENCE

Predominant Enhancement of Glucose Uptake in Astrocytes versus Neurons during Activation of the Somatosensory Cortex

(2010) J. Chuquet et al.   JOURNAL OF NEUROSCIENCE

Blood Lactate is an Important Energy Source for the Human Brain

(2009) Gerrit van Hall et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Astrocytes are poised for lactate trafficking and release from activated brain and for supply of glucose to neurons

(2009) Gautam K. Gandhi et al.   JOURNAL OF NEUROCHEMISTRY

Neuronal glucose but not lactate utilization is positively correlated with NMDA-induced neurotransmission and fluctuations in cytosolic Ca2+levels

(2009) Lasse K. Bak et al.   JOURNAL OF NEUROCHEMISTRY

Thein vivoneuron-to-astrocyte lactate shuttle in human brain: evidence from modeling of measured lactate levels during visual stimulation

(2009) Silvia Mangia et al.   JOURNAL OF NEUROCHEMISTRY

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1

(2009) Angel Herrero-Mendez et al.   NATURE CELL BIOLOGY