Loss of Acid Sensing Ion Channel-1a and Bicarbonate Administration Attenuate the Severity of Traumatic Brain Injury

Inflammation and white matter degeneration persist for years after a single traumatic brain injury

(2013) Victoria E. Johnson et al.   BRAIN

Delayed neurovascular inflammation after mild traumatic brain injury in rats

(2013) Yu-Duan Tsai et al.   BRAIN INJURY

Animal models of traumatic brain injury

(2013) Ye Xiong et al.   NATURE REVIEWS NEUROSCIENCE

Long-Term Upregulation of Inflammation and Suppression of Cell Proliferation in the Brain of Adult Rats Exposed to Traumatic Brain Injury Using the Controlled Cortical Impact Model

(2013) Sandra A. Acosta et al.   PLoS One

Structure and activity of the acid-sensing ion channels

(2012) Thomas W. Sherwood et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits

(2012) Zong Zhuang et al.   BMC NEUROSCIENCE

Targeted Gene Inactivation of Calpain-1 Suppresses Cortical Degeneration Due to Traumatic Brain Injury and Neuronal Apoptosis Induced by Oxidative Stress

(2012) Kaori H. Yamada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Repetitive Mild Traumatic Brain Injury in a Mouse Model Produces Learning and Memory Deficits Accompanied by Histological Changes

(2012) Benoit Mouzon et al.   JOURNAL OF NEUROTRAUMA

Medial Septal Nucleus Theta Frequency Deep Brain Stimulation Improves Spatial Working Memory after Traumatic Brain Injury

(2012) Darrin J. Lee et al.   JOURNAL OF NEUROTRAUMA

The Neuropathology and Neurobiology of Traumatic Brain Injury

(2012) Kaj Blennow et al.   NEURON

Progesterone is neuroprotective against ischemic brain injury through its effects on the phosphoinositide 3-kinase/protein kinase B signaling pathway

(2012) T. Ishrat et al.   NEUROSCIENCE

Inflammation after trauma: Microglial activation and traumatic brain injury

(2011) Anil F. Ramlackhansingh et al.   ANNALS OF NEUROLOGY

ASICs mediate the modulatory effect by paeoniflorin on alpha-synuclein autophagic degradation

(2011) Xue Sun et al.   BRAIN RESEARCH

Impairment of synaptic plasticity in hippocampus is exacerbated by methylprednisolone in a rat model of traumatic brain injury

(2011) Baoliang Zhang et al.   BRAIN RESEARCH

Heteromeric Acid-Sensing Ion Channels (ASICs) Composed of ASIC2b and ASIC1a Display Novel Channel Properties and Contribute to Acidosis-Induced Neuronal Death

(2011) T. W. Sherwood et al.   JOURNAL OF NEUROSCIENCE

Interstitial F2-Isoprostane 8-Iso-PGF2α As a Biomarker of Oxidative Stress after Severe Human Traumatic Brain Injury

(2011) Fredrik Clausen et al.   JOURNAL OF NEUROTRAUMA

Randomized Controlled Trial Comparing the Effect of 8.4% Sodium Bicarbonate and 5% Sodium Chloride on Raised Intracranial Pressure after Traumatic Brain Injury

(2011) Chris P. Bourdeaux et al.   Neurocritical Care

Neuronal Deletion of Caspase 8 Protects against Brain Injury in Mouse Models of Controlled Cortical Impact and Kainic Acid-Induced Excitotoxicity

(2011) Maryla Krajewska et al.   PLoS One

Calcium, ischemia and excitotoxicity

(2010) Kinga Szydlowska et al.   CELL CALCIUM

Cell Type-Specific Expression of Acid-Sensing Ion Channels in Hippocampal Interneurons

(2010) J. Y. Weng et al.   JOURNAL OF NEUROSCIENCE

Sodium Bicarbonate Lowers Intracranial Pressure After Traumatic Brain Injury

(2010) Chris Bourdeaux et al.   Neurocritical Care

ASICs aggravate acidosis-induced injuries during ischemic reperfusion

(2010) Ling Gu et al.   NEUROSCIENCE LETTERS

Acid-Sensing Ion Channels (ASICs): Pharmacology and implication in pain

(2010) Emmanuel Deval et al.   PHARMACOLOGY & THERAPEUTICS

The Amygdala Is a Chemosensor that Detects Carbon Dioxide and Acidosis to Elicit Fear Behavior

(2009) Adam E. Ziemann et al.   CELL

Alteration of synaptic transmission in the hippocampal-mPFC pathway during extinction trials of context-dependent fear memory in juvenile rat stress models

(2009) Hiroyo Koseki et al.   SYNAPSE

Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism

(2008) Hon Kit Wong et al.   HUMAN MOLECULAR GENETICS

Differential Hippocampal Protection when Blocking Intracellular Sodium and Calcium Entry during Traumatic Brain Injury in Rats

(2008) Xueren Zhao et al.   JOURNAL OF NEUROTRAUMA

Seizure termination by acidosis depends on ASIC1a

(2008) Adam E Ziemann et al.   NATURE NEUROSCIENCE

Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases

(2007) Z XIONG et al.   CURRENT OPINION IN PHARMACOLOGY