The role of DNA methylation in the pathogenesis of type 2 diabetes mellitus
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Title
The role of DNA methylation in the pathogenesis of type 2 diabetes mellitus
Authors
Keywords
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Journal
Clinical Epigenetics
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-07-11
DOI
10.1186/s13148-020-00896-4
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Note: Only part of the references are listed.- The orphan nuclear receptor Nor1/Nr4a3 is a negative regulator of β-cell mass
- (2019) Anne-Françoise Close et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dishevelled: A masterful conductor of complex Wnt signals
- (2018) Monica Sharma et al. CELLULAR SIGNALLING
- Diabetes pathogenic mechanisms and potential new therapies based upon a novel target called TXNIP
- (2018) Lance Thielen et al. Current Opinion in Endocrinology Diabetes and Obesity
- Lysyl oxidase-like 2 inhibition ameliorates glomerulosclerosis and albuminuria in diabetic nephropathy
- (2018) Stefanie Stangenberg et al. Scientific Reports
- Blood-Based DNA Methylation Biomarkers for Type 2 Diabetes: Potential for Clinical Applications
- (2018) Tarryn Willmer et al. Frontiers in Endocrinology
- Covalent inhibition of protein tyrosine phosphatases
- (2017) Kasi Viswanatharaju Ruddraraju et al. Molecular BioSystems
- Insulin action and resistance in obesity and type 2 diabetes
- (2017) Michael P Czech NATURE MEDICINE
- DNA methylation and its role in the pathogenesis of diabetes
- (2017) Amita Bansal et al. PEDIATRIC DIABETES
- DNA methylation of candidate genes in peripheral blood from patients with type 2 diabetes or the metabolic syndrome
- (2017) Sanne D. van Otterdijk et al. PLoS One
- Interactions between PPAR Gamma and the Canonical Wnt/Beta-Catenin Pathway in Type 2 Diabetes and Colon Cancer
- (2017) Yves Lecarpentier et al. PPAR Research
- Elevation of PTPN1 promoter methylation is a significant risk factor of type 2 diabetes in the Chinese population
- (2017) Qing Huang et al. Experimental and Therapeutic Medicine
- TCF7L2 rs290481 T>C polymorphism is associated with an increased risk of type 2 diabetes mellitus and fasting plasma glucose level
- (2017) Li Zhu et al. Oncotarget
- The shortening of leukocyte telomere length relates to DNA hypermethylation of LINE-1 in type 2 diabetes mellitus
- (2017) Yue Wu et al. Oncotarget
- The association between Alu hypomethylation and severity of type 2 diabetes mellitus
- (2017) Jirapan Thongsroy et al. Clinical Epigenetics
- Differential DNA methylation of MSI2 and its correlation with diabetic traits
- (2017) Jae-Pil Jeon et al. PLoS One
- DNA demethylation pathways: Additional players and regulators
- (2016) Matthias Bochtler et al. BIOESSAYS
- SOCS3 revisited: a broad regulator of disease, now ready for therapeutic use?
- (2016) R. Mahony et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Spectrum and Prevalence ofCALM1-,CALM2-, andCALM3-Encoded Calmodulin Variants in Long QT Syndrome and Functional Characterization of a Novel Long QT Syndrome–Associated Calmodulin Missense Variant, E141GCLINICAL PERSPECTIVE
- (2016) Nicole J. Boczek et al. Circulation-Cardiovascular Genetics
- DNA methylation of loci withinABCG1andPHOSPHO1in blood DNA is associated with future type 2 diabetes risk
- (2016) Tasnim Dayeh et al. Epigenetics
- PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance
- (2016) Nilotpal Roy et al. GENES & DEVELOPMENT
- PGC-1α, glucose metabolism and type 2 diabetes mellitus
- (2016) Haijiang Wu et al. JOURNAL OF ENDOCRINOLOGY
- Epigenetic changes in diabetes
- (2016) Rami Al-Haddad et al. NEUROSCIENCE LETTERS
- Inhibition of DNA methyltransferase 1 increases nuclear receptor subfamily 4 group A member 1 expression and decreases blood glucose in type 2 diabetes
- (2016) Yng-Tay Chen et al. Oncotarget
- Spectrum and Prevalence ofCALM1-,CALM2-, andCALM3-Encoded Calmodulin Variants in Long QT Syndrome and Functional Characterization of a Novel Long QT Syndrome–Associated Calmodulin Missense Variant, E141GCLINICAL PERSPECTIVE
- (2016) Nicole J. Boczek et al. Circulation-Cardiovascular Genetics
- Epigenetic alterations in patients with type 2 diabetes mellitus
- (2015) S Karachanak-Yankova et al. Balkan Journal of Medical Genetics
- Does epigenetic dysregulation of pancreatic islets contribute to impaired insulin secretion and type 2 diabetes?
- (2015) Tasnim Dayeh et al. Biochemistry and Cell Biology
- Novel epigenetic determinants of type 2 diabetes in Mexican-American families
- (2015) Hemant Kulkarni et al. HUMAN MOLECULAR GENETICS
- Epigenome-wide association study identifiesTXNIPgene associated with type 2 diabetes mellitus and sustained hyperglycemia
- (2015) Carolina Soriano-Tárraga et al. HUMAN MOLECULAR GENETICS
- PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes
- (2015) Yng-Tay Chen et al. Oncotarget
- Increased DNA methylation of the SLC30A8 gene promoter is associated with type 2 diabetes in a Malay population
- (2015) Norhashimah Seman et al. Clinical Epigenetics
- Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study
- (2015) John C Chambers et al. Lancet Diabetes & Endocrinology
- Long-Term Pancreatic Beta Cell Exposure to High Levels of Glucose but Not Palmitate Induces DNA Methylation within the Insulin Gene Promoter and Represses Transcriptional Activity
- (2015) Kota Ishikawa et al. PLoS One
- DNA methylation in obesity and type 2 diabetes
- (2014) Vanessa Derenji Ferreira de Mello et al. ANNALS OF MEDICINE
- Epigenetic Regulation of the DLK1-MEG3 MicroRNA Cluster in Human Type 2 Diabetic Islets
- (2014) Vasumathi Kameswaran et al. Cell Metabolism
- Increasing the Coding Potential of Genomes Through Alternative Splicing: The Case of PARK2 Gene
- (2014) Valentina La Cognata et al. CURRENT GENOMICS
- Altered DNA Methylation and Differential Expression of Genes Influencing Metabolism and Inflammation in Adipose Tissue From Subjects With Type 2 Diabetes
- (2014) E. Nilsson et al. DIABETES
- GLUT2, glucose sensing and glucose homeostasis
- (2014) Bernard Thorens DIABETOLOGIA
- Rola genu podatności na otyłość (FTO) w rozwoju otyłości — przegląd
- (2014) Aleksandra Zdrojowy-Wełna et al. Endokrynologia Polska
- Type 2 diabetes mellitus in relation to global LINE-1 DNA methylation in peripheral blood: A cohort study
- (2014) Gracia María Martín-Núñez et al. Epigenetics
- Elevated CpG island methylation of GCK gene predicts the risk of type 2 diabetes in Chinese males
- (2014) Linlin Tang et al. GENE
- The pivotal role of pyruvate dehydrogenase kinases in metabolic flexibility
- (2014) Shuai Zhang et al. Nutrition & Metabolism
- Differential Methylation of TCF7L2 Promoter in Peripheral Blood DNA in Newly Diagnosed, Drug-Naïve Patients with Type 2 Diabetes
- (2014) Silvia Canivell et al. PLoS One
- DNA Methylation in Mammals
- (2014) E. Li et al. Cold Spring Harbor Perspectives in Biology
- BCL11A gene DNA methylation contributes to the risk of type 2 diabetes in males
- (2014) LINLIN TANG et al. Experimental and Therapeutic Medicine
- Investigation into the promoter DNA methylation of three genes (CAMK1D, CRY2 and CALM2) in the peripheral blood of patients with type 2 diabetes
- (2014) JIA CHENG et al. Experimental and Therapeutic Medicine
- An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins
- (2014) Wei Yuan et al. Nature Communications
- Identification of a Regulatory Variant That Binds FOXA1 and FOXA2 at the CDC123/CAMK1D Type 2 Diabetes GWAS Locus
- (2014) Marie P. Fogarty et al. PLoS Genetics
- Genome-Wide DNA Methylation Analysis of Human Pancreatic Islets from Type 2 Diabetic and Non-Diabetic Donors Identifies Candidate Genes That Influence Insulin Secretion
- (2014) Tasnim Dayeh et al. PLoS Genetics
- A Central Role for GRB10 in Regulation of Islet Function in Man
- (2014) Inga Prokopenko et al. PLoS Genetics
- DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets
- (2013) Elin Hall et al. BMC Medical Genetics
- Effects of Common Genetic Variants Associated With Type 2 Diabetes and Glycemic Traits on α- and β-Cell Function and Insulin Action in Humans
- (2013) Anna Jonsson et al. DIABETES
- Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets
- (2013) T. A. Dayeh et al. DIABETOLOGIA
- Osteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolism
- (2013) A. Bozec et al. JOURNAL OF CELL SCIENCE
- The PARK2 gene is involved in the maintenance of pancreatic β-cell functions related to insulin production and secretion
- (2013) Hyun-Seok Jin et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- No association between IRS-1 promoter methylation and type 2 diabetes
- (2013) JIANGBO MA et al. Molecular Medicine Reports
- Epigenetic regulation and cancer (Review)
- (2013) Q.W. CHEN et al. ONCOLOGY REPORTS
- Gastric Inhibitory Polypeptide Receptor Methylation in Newly Diagnosed, Drug-Naïve Patients with Type 2 Diabetes: A Case-Control Study
- (2013) Silvia Canivell et al. PLoS One
- Arx Polyalanine Expansion in Mice Leads to Reduced Pancreatic α-Cell Specification and Increased α-Cell Death
- (2013) Crystal L. Wilcox et al. PLoS One
- ARX/Arx is expressed in germ cells during spermatogenesis in both marsupial and mouse
- (2013) Hongshi Yu et al. REPRODUCTION
- Evaluation of IGFBP-7 DNA methylation changes and serum protein variation in Swedish subjects with and without type 2 diabetes
- (2013) Harvest F Gu et al. Clinical Epigenetics
- Increased DNA methylation levels of the insulin-like growth factor binding protein 1 gene are associated with type 2 diabetes in Swedish men
- (2013) Tianwei Gu et al. Clinical Epigenetics
- Hypermethylation of the PRKCZ Gene in Type 2 Diabetes Mellitus
- (2013) Li Zou et al. Journal of Diabetes Research
- Loss of Both ABCA1 and ABCG1 Results in Increased Disturbances in Islet Sterol Homeostasis, Inflammation, and Impaired -Cell Function
- (2012) J. K. Kruit et al. DIABETES
- Insights Into the Molecular Mechanism for Type 2 Diabetes Susceptibility at the KCNQ1 Locus From Temporal Changes in Imprinting Status in Human Islets
- (2012) M. E. Travers et al. DIABETES
- SLC2A2 mutations can cause neonatal diabetes, suggesting GLUT2 may have a role in human insulin secretion
- (2012) F. H. Sansbury et al. DIABETOLOGIA
- DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients
- (2012) Michael Volkmar et al. EMBO JOURNAL
- Increased DNA Methylation and Decreased Expression ofPDX-1in Pancreatic Islets from Patients with Type 2 Diabetes
- (2012) Beatrice T. Yang et al. MOLECULAR ENDOCRINOLOGY
- Genome-Wide Association Scan for Survival on Dialysis in African-Americans with Type 2 Diabetes
- (2011) Mariana Murea et al. AMERICAN JOURNAL OF NEPHROLOGY
- Genome-wide association studies and type 2 diabetes
- (2011) E. Wheeler et al. Briefings in Functional Genomics
- Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort
- (2011) Yi-Cheng Chang et al. CLINICAL ENDOCRINOLOGY
- Pancreatic β Cell Identity Is Maintained by DNA Methylation-Mediated Repression of Arx
- (2011) Sangeeta Dhawan et al. DEVELOPMENTAL CELL
- Insulin effects in muscle and adipose tissue
- (2011) George Dimitriadis et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals
- (2011) J. E. Below et al. DIABETOLOGIA
- Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood
- (2011) Gidon Toperoff et al. HUMAN MOLECULAR GENETICS
- Islet-1 RegulatesArxTranscription during Pancreatic Islet α-Cell Development
- (2011) Jingxuan Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Variation of serum monocyte chemoattractant protein-1 in patients with diabetes and metabolic syndrome
- (2011) Huiqing Li et al. Journal of Huazhong University of Science and Technology-Medical Sciences
- Mitochondrial regulators of fatty acid metabolism reflect metabolic dysfunction in type 2 diabetes mellitus
- (2011) Sameer S. Kulkarni et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes
- (2011) M Szabat et al. Cell Death & Disease
- The suppressor of cytokine signalling 2 (SOCS2) is a key repressor of insulin secretion
- (2010) P. Lebrun et al. DIABETOLOGIA
- Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic islets
- (2010) B. T. Yang et al. DIABETOLOGIA
- Epigenetics and gene expression
- (2010) E R Gibney et al. HEREDITY
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
- (2010) Josée Dupuis et al. NATURE GENETICS
- Downregulation of ZnT8 expression in pancreatic β-cells of diabetic mice
- (2010) Motoyuki Tamaki et al. Islets
- A Genome-Wide Association Study Identifies Susceptibility Variants for Type 2 Diabetes in Han Chinese
- (2010) Fuu-Jen Tsai et al. PLoS Genetics
- Gene Variants in the Novel Type 2 Diabetes Loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B Affect Different Aspects of Pancreatic -Cell Function
- (2009) A. M. Simonis-Bik et al. DIABETES
- The role of insulin-like growth factor-I and its binding proteins in glucose homeostasis and type 2 diabetes
- (2009) Swapnil N. Rajpathak et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- An operational definition of epigenetics
- (2009) S. L. Berger et al. GENES & DEVELOPMENT
- Monocyte Chemoattractant Protein-1 (MCP-1): An Overview
- (2009) Satish L. Deshmane et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Insulin Gene Expression Is Regulated by DNA Methylation
- (2009) Akio Kuroda et al. PLoS One
- Association of Variants in the Sterol Regulatory Element-Binding Factor 1 (SREBF1) Gene With Type 2 Diabetes, Glycemia, and Insulin Resistance: A Study of 15,734 Danish Subjects
- (2008) N. Grarup et al. DIABETES
- Hypermethylation of hepatic Gck promoter in ageing rats contributes to diabetogenic potential
- (2008) M. H. Jiang et al. DIABETOLOGIA
- Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion
- (2008) C. Ling et al. DIABETOLOGIA
- Circulating IGF-binding protein 7 (IGFBP7) levels are elevated in patients with endometriosis or undergoing diabetic hemodialysis
- (2008) Masahiko Kutsukake et al. Reproductive Biology and Endocrinology
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