Novel epigenetic determinants of type 2 diabetes in Mexican-American families

Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs

(2014) Wilma T. Steegenga et al.   AGE

Accounting for Population Stratification in DNA Methylation Studies

(2014) Richard T. Barfield et al.   GENETIC EPIDEMIOLOGY

Sterol Regulatory Element-binding Protein-1 (SREBP-1) Is Required to Regulate Glycogen Synthesis and Gluconeogenic Gene Expression in Mouse Liver

(2014) Rafaela Ruiz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sucrose-conditioned flavor preferences in sweet ageusic T1r3 and Calhm1 knockout mice

(2014) Anthony Sclafani et al.   PHYSIOLOGY & BEHAVIOR

Mapping the Epigenetic Basis of Complex Traits

(2014) S. Cortijo et al.   SCIENCE

An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins

(2014) Wei Yuan et al.   Nature Communications

Gender-Specific DNA Methylome Analysis of a Han Chinese Longevity Population

(2014) Liang Sun et al.   Biomed Research International

Contribution of genetic variation to transgenerational inheritance of DNA methylation

(2014) Allan F McRae et al.   GENOME BIOLOGY

Accounting for cellular heterogeneity is critical in epigenome-wide association studies

(2014) Andrew E Jaffe et al.   GENOME BIOLOGY

Thioredoxin/Txnip: Redoxisome, as a Redox Switch for the Pathogenesis of Diseases

(2014) Eiji Yoshihara et al.   Frontiers in Immunology

A modified generalized Fisher method for combining probabilities from dependent tests

(2014) Hongying Dai et al.   Frontiers in Genetics

Inference of the Genetic Architecture Underlying BMI and Height with the Use of 20,240 Sibling Pairs

(2013) Gibran Hemani et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements

(2013) Elin Grundberg et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetics of type 2 diabetes and potential clinical implications

(2013) Soo Heon Kwak et al.   ARCHIVES OF PHARMACAL RESEARCH

Epigenetics: a new mechanism of regulation of heart failure?

(2013) Roberto Papait et al.   BASIC RESEARCH IN CARDIOLOGY

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Pathview: an R/Bioconductor package for pathway-based data integration and visualization

(2013) Weijun Luo et al.   BIOINFORMATICS

Expanding roles of ABCG1 and sterol transport

(2013) Elizabeth J. Tarling   CURRENT OPINION IN LIPIDOLOGY

Epigenome-Wide Association Study of Fasting Measures of Glucose, Insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network Study

(2013) B. Hidalgo et al.   DIABETES

Waist circumference is genetically correlated with incident Type 2 diabetes in Mexican-American families

(2013) M. Mamtani et al.   DIABETIC MEDICINE

A genome-wide methylation study on obesity

(2013) Xiaojing Xu et al.   Epigenetics

A combined LDL receptor/LDL receptor adaptor protein 1 mutation as the cause for severe familial hypercholesterolemia

(2013) Muhidien Soufi et al.   GENE

Sex-biased methylome and transcriptome in human prefrontal cortex

(2013) Hongqin Xu et al.   HUMAN MOLECULAR GENETICS

Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites

(2013) I. Florath et al.   HUMAN MOLECULAR GENETICS

Systemic sclerosis: Genetics and epigenetics

(2013) Yangyang Luo et al.   JOURNAL OF AUTOIMMUNITY

CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes

(2013) Akiyuki Taruno et al.   NATURE

Patterns of methylation heritability in a genome-wide analysis of four brain regions

(2013) Gerald Quon et al.   NUCLEIC ACIDS RESEARCH

Waist Circumference Independently Associates with the Risk of Insulin Resistance and Type 2 Diabetes in Mexican American Families

(2013) Manju Mamtani et al.   PLoS One

Genetic Effects on DNA Methylation and Its Potential Relevance for Obesity in Mexican Americans

(2013) Melanie A. Carless et al.   PLoS One

Genetic and epigenetic control of metabolic health

(2013) Robert Wolfgang Schwenk et al.   Molecular Metabolism

Methylation ofELOVL2gene as a new epigenetic marker of age

(2012) Paolo Garagnani et al.   AGING CELL

A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data

(2012) Andrew E. Teschendorff et al.   BIOINFORMATICS

DNA methylation arrays as surrogate measures of cell mixture distribution

(2012) Eugene Houseman et al.   BMC BIOINFORMATICS

High Glucose Induced Differential Expression of Lysyl Oxidase and Its Isoform in ARPE-19 Cells

(2012) Karunakaran Coral et al.   CURRENT EYE RESEARCH

ABC Transporter Genes and Risk of Type 2 Diabetes: A study of 40,000 individuals from the general population

(2012) J. Schou et al.   DIABETES CARE

DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

(2012) Michael Volkmar et al.   EMBO JOURNAL

Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence

(2012) L. Gordon et al.   GENOME RESEARCH

Cardiovascular epigenetics: From DNA methylation to microRNAs

(2012) Silvia Udali et al.   MOLECULAR ASPECTS OF MEDICINE

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

(2012) Gregory Hannum et al.   MOLECULAR CELL

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

What obesity research tells us about epigenetic mechanisms

(2012) N. A. Youngson et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility

(2012) Lovisa E. Reinius et al.   PLoS One

Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population

(2012) Jordana T. Bell et al.   PLoS Genetics

Thioredoxin interacting protein genetic variation is associated with diabetes and hypertension in the Brazilian general population

(2011) Noely E. Ferreira et al.   ATHEROSCLEROSIS

Timing is everything

(2011) Christopher Faulk et al.   Epigenetics

Genomic inflation factors under polygenic inheritance

(2011) Jian Yang et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood

(2011) Gidon Toperoff et al.   HUMAN MOLECULAR GENETICS

Reduced levels of serum IGF-1 is related to the presence of osteoporotic fractures in male idiopathic osteoporosis

(2011) Julien Paccou et al.   JOINT BONE SPINE

Detection of   cell death in diabetes using differentially methylated circulating DNA

(2011) E. M. Akirav et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-term effects of high-fat or high-carbohydrate diets on glucose tolerance in mice with heterozygous carnitine palmitoyltransferase-1a deficiency

(2011) L R Nyman et al.   Nutrition & Diabetes

Genetic Control of Individual Differences in Gene-Specific Methylation in Human Brain

(2010) Dandan Zhang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The genetics of type 2 diabetes: what have we learned from GWAS?

(2010) Liana K. Billings et al.   Annals of the New York Academy of Sciences

Sterol metabolism and SREBP activation

(2010) Ryuichiro Sato   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A flexible R package for nonnegative matrix factorization

(2010) Renaud Gaujoux et al.   BMC BIOINFORMATICS

Cut-like Homeobox 1 (CUX1) Regulates Expression of the Fat Mass and Obesity-associated and Retinitis Pigmentosa GTPase Regulator-interacting Protein-1-like (RPGRIP1L) Genes and Coordinates Leptin Receptor Signaling

(2010) George Stratigopoulos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: pooled individual data analysis of 17 prospective studies

(2010)   LANCET ONCOLOGY

Genetics of Atherosclerosis Risk Factors in Mexican Americans

(2010) Jean W. MacCluer et al.   NUTRITION REVIEWS

Sex-specific genetic dissection of diabetes in a rodent model identifies Ica1 and Ndufa4 as major candidate genes

(2010) Ronit Barkalifa et al.   PHYSIOLOGICAL GENOMICS

Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus

(2010) Christopher G. Bell et al.   PLoS One

Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain

(2010) J. Raphael Gibbs et al.   PLoS Genetics

The Sex-Determining Region Y-Box 4 and Homeobox C6 Transcriptional Networks in Prostate Cancer Progression

(2009) Carlos S. Moreno   AMERICAN JOURNAL OF PATHOLOGY

BSMAP: whole genome bisulfite sequence MAPping program

(2009) Yuanxin Xi et al.   BMC BIOINFORMATICS

DNA methylation profiles in monozygotic and dizygotic twins

(2009) Zachary A Kaminsky et al.   NATURE GENETICS

The Relationship of DNA Methylation with Age, Gender and Genotype in Twins and Healthy Controls

(2009) Marco P. Boks et al.   PLoS One

Aging and Environmental Exposures Alter Tissue-Specific DNA Methylation Dependent upon CpG Island Context

(2009) Brock C. Christensen et al.   PLoS Genetics

Reduced Expression of ATP-Binding Cassette Transporter G1 Increases Cholesterol Accumulation in Macrophages of Patients With Type 2 Diabetes Mellitus

(2008) Jeremy P. Mauldin et al.   CIRCULATION

Association of Variants in the Sterol Regulatory Element-Binding Factor 1 (SREBF1) Gene With Type 2 Diabetes, Glycemia, and Insulin Resistance: A Study of 15,734 Danish Subjects

(2008) N. Grarup et al.   DIABETES

Genetics of variation in HOMA-IR and cardiovascular risk factors in Mexican-Americans

(2008) V. Saroja Voruganti et al.   JOURNAL OF MOLECULAR MEDICINE-JMM