Epigenome-wide association study identifiesTXNIPgene associated with type 2 diabetes mellitus and sustained hyperglycemia

Type 2 diabetes and leucocyte DNA methylation: an epigenome-wide association study in over 1,500 older adults

(2015) Ines Florath et al.   DIABETOLOGIA

The human blood DNA methylome displays a highly distinctive profile compared with other somatic tissues

(2015) Robert Lowe et al.   Epigenetics

Novel epigenetic determinants of type 2 diabetes in Mexican-American families

(2015) Hemant Kulkarni et al.   HUMAN MOLECULAR GENETICS

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

(2015) John C Chambers et al.   Lancet Diabetes & Endocrinology

DNA methylation in obesity and type 2 diabetes

(2014) Vanessa Derenji Ferreira de Mello et al.   ANNALS OF MEDICINE

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

(2014) Martin J. Aryee et al.   BIOINFORMATICS

Effects of cytosine methylation on transcription factor binding sites

(2014) Yulia A Medvedeva et al.   BMC GENOMICS

Multiple Nonglycemic Genomic Loci Are Newly Associated With Blood Level of Glycated Hemoglobin in East Asians

(2014) P. Chen et al.   DIABETES

Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation

(2014) Loukia G Tsaprouni et al.   Epigenetics

Comprehensive analysis of DNA methylation data with RnBeads

(2014) Yassen Assenov et al.   NATURE METHODS

High-resolution digital profiling of the epigenome

(2014) Gabriel E. Zentner et al.   NATURE REVIEWS GENETICS

The Role of HbA1c Determination in Detecting Unknown Glucose Disturbances in Ischemic Stroke

(2014) Jaume Roquer et al.   PLoS One

An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins

(2014) Wei Yuan et al.   Nature Communications

Thioredoxin/Txnip: Redoxisome, as a Redox Switch for the Pathogenesis of Diseases

(2014) Eiji Yoshihara et al.   Frontiers in Immunology

A data-driven approach to preprocessing Illumina 450K methylation array data

(2013) Ruth Pidsley et al.   BMC GENOMICS

A comprehensive overview of Infinium HumanMethylation450 data processing

(2013) S. Dedeurwaerder et al.   BRIEFINGS IN BIOINFORMATICS

Epigenome-Wide Association Study of Fasting Measures of Glucose, Insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network Study

(2013) B. Hidalgo et al.   DIABETES

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

(2013) Yi-an Chen et al.   Epigenetics

Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits

(2013) Ann-Kristin Petersen et al.   HUMAN MOLECULAR GENETICS

Cross-talk between Site-specific Transcription Factors and DNA Methylation States

(2013) Adam Blattler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1

(2013) Ning Wu et al.   MOLECULAR CELL

Tobacco Smoking Leads to Extensive Genome-Wide Changes in DNA Methylation

(2013) Sonja Zeilinger et al.   PLoS One

Diabetes Mellitus

(2013) Jane C. Khoury et al.   STROKE

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

DNA methylation arrays as surrogate measures of cell mixture distribution

(2012) Eugene Houseman et al.   BMC BIOINFORMATICS

The Epigenome and Its Role in Diabetes

(2012) Hironori Waki et al.   Current Diabetes Reports

Hemoglobin A1cin Diabetes: Panacea or Pointless?

(2012) David B. Sacks   DIABETES

Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking

(2012) Natalie S. Shenker et al.   HUMAN MOLECULAR GENETICS

Roles of thioredoxin binding protein (TXNIP) in oxidative stress, apoptosis and cancer

(2012) Jianbiao Zhou et al.   MITOCHONDRION

DNA methylation profiling in the clinic: applications and challenges

(2012) Holger Heyn et al.   NATURE REVIEWS GENETICS

The emerging challenge in diabetes: The “metabolic memory”

(2012) Antonio Ceriello   VASCULAR PHARMACOLOGY

Complete pipeline for Infinium® Human Methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation

(2012) Nizar Touleimat et al.   Epigenomics

SWAN: Subset-quantile Within Array Normalization for Illumina Infinium HumanMethylation450 BeadChips

(2012) Jovana Maksimovic et al.   GENOME BIOLOGY

Aging effects on DNA methylation modules in human brain and blood tissue

(2012) Steve Horvath et al.   GENOME BIOLOGY

Thioredoxin Interacting Protein: Redox Dependent and Independent Regulatory Mechanisms

(2011) Oded N. Spindel et al.   ANTIOXIDANTS & REDOX SIGNALING

The influence of aging, environmental exposures and local sequence features on the variation of DNA methylation in blood

(2011) Scott M. Langevin et al.   Epigenetics

DNA methylation in white blood cells

(2011) Mary Beth Terry et al.   Epigenetics

Significant differences in global genomic DNA methylation by gender and race/ethnicity in peripheral blood

(2011) Fang Fang Zhang et al.   Epigenetics

Assigning roles to DNA regulatory motifs using comparative genomics

(2010) Fabian A. Buske et al.   BIOINFORMATICS

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

(2010) Pan Du et al.   BMC BIOINFORMATICS

Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated

(2010) Mun-Kit Choy et al.   BMC GENOMICS

Deletion of the  -Arrestin Protein Txnip in Mice Promotes Adiposity and Adipogenesis While Preserving Insulin Sensitivity

(2010) W. A. Chutkow et al.   DIABETES

Predictors of global methylation levels in blood DNA of healthy subjects: a combined analysis

(2010) Zhong-Zheng Zhu et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies

(2010) The Emerging Risk Factors Collaboration   LANCET

Epigenetic modifications and human disease

(2010) Anna Portela et al.   NATURE BIOTECHNOLOGY

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

Epigenetic phenomena linked to diabetic complications

(2010) Luciano Pirola et al.   Nature Reviews Endocrinology

Genomics, Type 2 Diabetes, and Obesity

(2010) Mark I. McCarthy   NEW ENGLAND JOURNAL OF MEDICINE

The Relationship of DNA Methylation with Age, Gender and Genotype in Twins and Healthy Controls

(2009) Marco P. Boks et al.   PLoS One

Epigenetic mechanisms in the development of type 2 diabetes

(2009) Sara E. Pinney et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Diabetes and modifiable risk factors for cardiovascular disease: the prospective Million Women Study

(2008) Elizabeth A. Spencer et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Acute stroke unit care and early neurological deterioration in ischemic stroke

(2008) Jaume Roquer et al.   JOURNAL OF NEUROLOGY