Long-Term Pancreatic Beta Cell Exposure to High Levels of Glucose but Not Palmitate Induces DNA Methylation within the Insulin Gene Promoter and Represses Transcriptional Activity
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Title
Long-Term Pancreatic Beta Cell Exposure to High Levels of Glucose but Not Palmitate Induces DNA Methylation within the Insulin Gene Promoter and Represses Transcriptional Activity
Authors
Keywords
DNA methylation, Insulin, Glucose, Polymerase chain reaction, Diabetes mellitus, DNA transcription, Epigenetics, Type 2 diabetes
Journal
PLoS One
Volume 10, Issue 2, Pages e0115350
Publisher
Public Library of Science (PLoS)
Online
2015-02-07
DOI
10.1371/journal.pone.0115350
References
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