The pivotal role of pyruvate dehydrogenase kinases in metabolic flexibility
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Title
The pivotal role of pyruvate dehydrogenase kinases in metabolic flexibility
Authors
Keywords
PDC, PDK, Metabolic flexibility
Journal
Nutrition & Metabolism
Volume 11, Issue 1, Pages 10
Publisher
Springer Nature
Online
2014-02-12
DOI
10.1186/1743-7075-11-10
References
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Note: Only part of the references are listed.- ANG II causes insulin resistance and induces cardiac metabolic switch and inefficiency: a critical role of PDK4
- (2013) Jun Mori et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
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- (2013) Ching-An Wu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
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- (2013) Rongya Tao et al. PLoS One
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- (2012) Eric A.F. Herbst et al. Applied Physiology Nutrition and Metabolism
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- (2012) Mithilesh Kumar Jha et al. Current Neuropharmacology
- Metformin Inhibits Growth Hormone-Mediated Hepatic PDK4 Gene Expression Through Induction of Orphan Nuclear Receptor Small Heterodimer Partner
- (2012) Y. D. Kim et al. DIABETES
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- (2012) Dumitru Constantin-Teodosiu et al. DIABETES
- Additive effects of clofibric acid and pyruvate dehydrogenase kinase isoenzyme 4 (PDK4) deficiency on hepatic steatosis in mice fed a high saturated fat diet
- (2012) Byounghoon Hwang et al. FEBS Journal
- Activating cardiac E2F1 induces up-regulation of pyruvate dehydrogenase kinase 4 in mice on a short term of high fat feeding
- (2012) Liyan Zhang et al. FEBS LETTERS
- Malonyl-CoA: the regulator of fatty acid synthesis and oxidation
- (2012) Daniel W. Foster JOURNAL OF CLINICAL INVESTIGATION
- Effects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle
- (2012) Rita Rinnankoski-Tuikka et al. Nutrition & Metabolism
- Pronounced Effects of Acute Endurance Exercise on Gene Expression in Resting and Exercising Human Skeletal Muscle
- (2012) Milène Catoire et al. PLoS One
- Transcriptional Regulation of Pyruvate Dehydrogenase Kinase
- (2012) Ji Yun Jeong et al. Diabetes & Metabolism Journal
- PGC-1α encoded by the PPARGC1A gene regulates oxidative energy metabolism in equine skeletal muscle during exercise
- (2011) S. S. Eivers et al. ANIMAL GENETICS
- PPARα–LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status
- (2011) Paul W. Caton et al. BIOCHEMICAL JOURNAL
- Regulation of Pyruvate Dehydrogenase Kinase 4 (PDK4) by CCAAT/Enhancer-binding Protein β (C/EBPβ)
- (2011) Ramy R. Attia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial regulators of fatty acid metabolism reflect metabolic dysfunction in type 2 diabetes mellitus
- (2011) Sameer S. Kulkarni et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Epinephrine Induces PDK4 mRNA Expression in Adipose Tissue From Obese, Insulin Resistant Rats
- (2011) Zhongxiao Wan et al. Obesity
- Epinephrine-mediated regulation of PDK4 mRNA in rat adipose tissue
- (2010) Zhongxiao Wan et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Regulation of Islet β-Cell Pyruvate Metabolism: Interactions of Prolactin, Glucose, and Dexamethasone
- (2010) Ramamani Arumugam et al. ENDOCRINOLOGY
- Hypothalamic Responses to Fasting Indicate Metabolic Reprogramming Away from Glycolysis Toward Lipid Oxidation
- (2010) Michal M. Poplawski et al. ENDOCRINOLOGY
- Deoxyribonucleic Acid Methylation and Gene Expression ofPPARGC1Ain Human Muscle Is Influenced by High-Fat Overfeeding in a Birth-Weight-Dependent Manner
- (2010) Charlotte Brøns et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Neonatal Maternal Deprivation Response and Developmental Changes in Gene Expression Revealed by Hypothalamic Gene Expression Profiling in Mice
- (2010) Feng Ding et al. PLoS One
- Pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) deficiency attenuates the long-term negative effects of a high-saturated fat diet
- (2009) Byounghoon Hwang et al. BIOCHEMICAL JOURNAL
- Non-CpG Methylation of the PGC-1α Promoter through DNMT3B Controls Mitochondrial Density
- (2009) Romain Barrès et al. Cell Metabolism
- Pyruvate dehydrogenase kinase 4 expression is synergistically induced by AMP-activated protein kinase and fatty acids
- (2009) S. M. Houten et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Regulation of Pyruvate Dehydrogenase Kinase 4 (PDK4) by Thyroid Hormone
- (2009) Ramy R. Attia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) gene expression by glucocorticoids and insulin
- (2009) Sara Connaughton et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- PPARs and the orchestration of metabolic fuel selection
- (2009) Mary C. Sugden et al. PHARMACOLOGICAL RESEARCH
- Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
- (2009) J. Yao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice
- (2008) Nam Ho Jeoung et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
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- (2008) Jose E. Galgani et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
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- (2008) Peggy P. Hsu et al. CELL
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- (2008) T. Cadoudal et al. DIABETES
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- (2008) Colleen K. Nye et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CD36-dependent Regulation of Muscle FoxO1 and PDK4 in the PPARδ/β-mediated Adaptation to Metabolic Stress
- (2008) Zaher Nahlé et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The role of FoxO in the regulation of metabolism
- (2008) D N Gross et al. ONCOGENE
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- (2007) Guixiang Zhao et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
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