Effects of Oxidative Stress on Protein Translation: Implications for Cardiovascular Diseases

A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging

(2020) Haopeng Xiao et al.   CELL

IRES Trans-Acting Factors, Key Actors of the Stress Response

(2019) Anne-Claire Godet et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Early dysregulation of cardiac-specific microRNA-208a is linked to maladaptive cardiac remodelling in diabetic myocardium

(2019) Shruti Rawal et al.   Cardiovascular Diabetology

MiR-499 inhibited hypoxia/reoxygenation induced cardiomyocytes injury by targeting SOX6

(2019) Yujie Shi et al.   BIOTECHNOLOGY LETTERS

Mitochondrial electron transport chain, ROS generation and uncoupling (Review)

(2019) Ru‑Zhou Zhao et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Inhibition of Mitofusin-2 Promotes Cardiac Fibroblast Activation via the PERK/ATF4 Pathway and Reactive Oxygen Species

(2019) Yanguo Xin et al.   Oxidative Medicine and Cellular Longevity

Dynamic UTR Usage Regulates Alternative Translation to Modulate Gap Junction Formation during Stress and Aging

(2019) Michael J. Zeitz et al.   Cell Reports

Oxidative stress injury in doxorubicin-induced cardiotoxicity

(2019) Mei Songbo et al.   TOXICOLOGY LETTERS

The mechanism of RNA oxidation involved in the development of heart failure

(2019) Tong Liu et al.   FREE RADICAL RESEARCH

eIF5B gates the transition from translation initiation to elongation

(2019) Jinfan Wang et al.   NATURE

How do cells cope with RNA damage and its consequences?

(2019) Liewei L. Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Stress in Cardiovascular Diseases: Still a Therapeutic Target?

(2019) Thomas Senoner et al.   Nutrients

The Impact of Oxidative Stress on Ribosomes: From Injury to Regulation

(2019) Natalia Shcherbik et al.   Cells

Structure and mechanisms of ROS generation by NADPH oxidases

(2019) Francesca Magnani et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

In vitro and in vivo cardioprotective and metabolic efficacy of vitamin E TPGS/Apelin

(2019) Patricia Leme Goto et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Oxidation and alkylation stresses activate ribosome-quality control

(2019) Liewei L. Yan et al.   Nature Communications

Vasohibin1, a new mouse cardiomyocyte IRES trans-acting factor that regulates translation in early hypoxia

(2019) Fransky Hantelys et al.   eLife

miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges

(2018) Shan-shan Zhou et al.   ACTA PHARMACOLOGICA SINICA

Down-regulation of miR-133a/b in patients with myocardial infarction correlates with the presence of ventricular fibrillation

(2018) Emanuela Boštjančič et al.   BIOMEDICINE & PHARMACOTHERAPY

New Insights Into the Role of mTOR Signaling in the Cardiovascular System

(2018) Sebastiano Sciarretta et al.   CIRCULATION RESEARCH

Iron-dependent cleavage of ribosomal RNA during oxidative stress in the yeastSaccharomyces cerevisiae.

(2018) Jessica A. Zinskie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stress-induced tRNA cleavage and tiRNA generation in rat neuronal PC12 cells

(2018) Alaa Elkordy et al.   JOURNAL OF NEUROCHEMISTRY

ROS signaling and ER stress in cardiovascular disease

(2018) Cristhiaan D. Ochoa et al.   MOLECULAR ASPECTS OF MEDICINE

Therapeutic Benefit and Gene Network Regulation by Combined Gene Transfer of Apelin, FGF2, and SERCA2a into Ischemic Heart

(2018) Edith Renaud-Gabardos et al.   MOLECULAR THERAPY

Nutrients and Oxidative Stress: Friend or Foe?

(2018) Bee Ling Tan et al.   Oxidative Medicine and Cellular Longevity

Translation Termination and Ribosome Recycling in Eukaryotes

(2018) Christopher U.T. Hellen   Cold Spring Harbor Perspectives in Biology

Translation Elongation and Recoding in Eukaryotes

(2018) Thomas E. Dever et al.   Cold Spring Harbor Perspectives in Biology

Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species

(2018) Ulrike Topf et al.   Nature Communications

The Transcription Factor ATF4 Promotes Expression of Cell Stress Genes and Cardiomyocyte Death in a Cellular Model of Atrial Fibrillation

(2018) Johanna K. Freundt et al.   Biomed Research International

Human Cardiac Gene Therapy

(2018) Kiyotake Ishikawa et al.   CIRCULATION RESEARCH

Role of the ISR-ATF4 pathway and its cross talk with Nrf2 in mitochondrial quality control

(2018) Shuya Kasai et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation

(2018) Sandra R. Bacman et al.   NATURE MEDICINE

Pathogenic variants in glutamyl-tRNAGln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder

(2018) Marisa W. Friederich et al.   Nature Communications

Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

(2018) Jacob O'Brien et al.   Frontiers in Endocrinology

APC-Cdh1 Regulates Neuronal Apoptosis Through Modulating Glycolysis and Pentose-Phosphate Pathway After Oxygen-Glucose Deprivation and Reperfusion

(2018) Zuofan Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The relevance of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D concentration for postoperative infections and postoperative organ dysfunctions in cardiac surgery patients: The eVIDenCe study

(2018) Julia Ney et al.   CLINICAL NUTRITION

GCN2 deficiency ameliorates cardiac dysfunction in diabetic mice by reducing lipotoxicity and oxidative stress

(2018) Wei Feng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Instability of the mitochondrial alanyl-tRNA synthetase underlies fatal infantile-onset cardiomyopathy

(2018) Ewen W Sommerville et al.   HUMAN MOLECULAR GENETICS

Revisiting the Closed-Loop Model and the Nature of mRNA 5′–3′ Communication

(2018) Quentin Vicens et al.   MOLECULAR CELL

Dietary Intake of Anti-Oxidant Vitamins A, C, and E Is Inversely Associated with Adverse Cardiovascular Outcomes in Chinese—A 22-Years Population-Based Prospective Study

(2018) Chi-Ho Lee et al.   Nutrients

Association between oxidative stress and atrial fibrillation

(2017) Ayman Samman Tahhan et al.   HEART RHYTHM

Endoplasmic Reticulum Stress and Oxidative Stress: A Vicious Nexus Implicated in Bowel Disease Pathophysiology

(2017) Wai Chong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endonucleolytic cleavage in the expansion segment 7 of 25S rRNA is an early marker of low-level oxidative stress in yeast

(2017) Daniel Shedlovskiy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A hypertension-associated mitochondrial DNA mutation introduces an m1G37 modification into tRNAMet, altering its structure and function

(2017) Mi Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Iron–sulfur cluster biogenesis and trafficking in mitochondria

(2017) Joseph J. Braymer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alterations of the translation apparatus during aging and stress response

(2017) Yulia Gonskikh et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Overexpressed microRNA-506 and microRNA-124 alleviate H2O2-induced human cardiomyocyte dysfunction by targeting krüppel-like factor 4/5

(2017) Xiuzhou Zhang et al.   Molecular Medicine Reports

The Efficacy of Cardiac Anti-miR-208a Therapy Is Stress Dependent

(2017) Joep E.C. Eding et al.   MOLECULAR THERAPY

Embraced by eIF3: structural and functional insights into the roles of eIF3 across the translation cycle

(2017) Leoš Shivaya Valášek et al.   NUCLEIC ACIDS RESEARCH

Dynamics of IRES-mediated translation

(2017) Alex G. Johnson et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Structural Insights into the Mechanism of Scanning and Start Codon Recognition in Eukaryotic Translation Initiation

(2017) Alan G. Hinnebusch   TRENDS IN BIOCHEMICAL SCIENCES

Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells

(2017) Inge M.N. Wortel et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mammalian Polycistronic mRNAs and Disease

(2017) Timofey A. Karginov et al.   TRENDS IN GENETICS

Induction of oxidative stress by anticancer drugs in the presence and absence of cells

(2017) Chikako Yokoyama et al.   Oncology Letters

A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure

(2017) Yufeng Yao et al.   Nature Communications

Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress

(2017) Pu Qin et al.   Journal of the American Heart Association

Oxidative stress and apoptosis after acute respiratory hypoxia and reoxygenation in rat brain

(2017) Debora Coimbra-Costa et al.   Redox Biology

Protein misfolding in neurodegenerative diseases: implications and strategies

(2017) Patrick Sweeney et al.   Translational Neurodegeneration

CVD and Oxidative Stress

(2017) Karla Cervantes Gracia et al.   Journal of Clinical Medicine

Transcriptional Regulation by Nrf2

(2017) Claudia Tonelli et al.   ANTIOXIDANTS & REDOX SIGNALING

Hypoxia and ER stress promote Staufen1 expression through an alternative translation mechanism

(2016) Florence Bonnet-Magnaval et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

4E-BP1, a multifactor regulated multifunctional protein

(2016) Xiaoyu Qin et al.   CELL CYCLE

SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation

(2016) Alexandre Prola et al.   CELL DEATH AND DIFFERENTIATION

Acquisition of pro-oxidant activity of fALS-linked SOD1 mutants as revealed using circular dichroism and UV-resonance Raman spectroscopy

(2016) Nobuhiro Fujimaki et al.   CHEMICAL PHYSICS

Contribution of mitochondrial oxidative stress to hypertension

(2016) Sergey I. Dikalov et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Upstream Open Reading Frames Differentially Regulate Gene-specific Translation in the Integrated Stress Response

(2016) Sara K. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Saffold virus infection associated with human myocarditis

(2016) Trine Skov Nielsen et al.   JOURNAL OF CLINICAL VIROLOGY

mTOR inactivation in myocardium from infant mice rapidly leads to dilated cardiomyopathy due to translation defects and p53/JNK-mediated apoptosis

(2016) Laetitia Mazelin et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiac-specific miRNA in cardiogenesis, heart function, and cardiac pathology (with focus on myocardial infarction)

(2016) Dimitry A. Chistiakov et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Electrophysiological and molecular mechanisms of paroxysmal atrial fibrillation

(2016) Stanley Nattel et al.   Nature Reviews Cardiology

Role of ROS and RNS Sources in Physiological and Pathological Conditions

(2016) Sergio Di Meo et al.   Oxidative Medicine and Cellular Longevity

ROS and ROS-Mediated Cellular Signaling

(2016) Jixiang Zhang et al.   Oxidative Medicine and Cellular Longevity

Resveratrol Protects against TNF-α-Induced Injury in Human Umbilical Endothelial Cells through Promoting Sirtuin-1-Induced Repression of NF-KB and p38 MAPK

(2016) Wei Pan et al.   PLoS One

Biological and physiological role of reactive oxygen species - the good, the bad and the ugly

(2015) L. Zuo et al.   Acta Physiologica

Fibroblast growth factors in cardiovascular disease: The emerging role of FGF21

(2015) Eleni M. Domouzoglou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Highly Predictive Reprogramming of tRNA Modifications Is Linked to Selective Expression of Codon-Biased Genes

(2015) Clement T. Y. Chan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Role of Antioxidants for the Treatment of Cardiovascular Diseases: Challenges and Opportunities

(2015) Amit Jain et al.   CURRENT PHARMACEUTICAL DESIGN

Influence of vitamin C and vitamin E on redox signaling: Implications for exercise adaptations

(2015) James N. Cobley et al.   FREE RADICAL BIOLOGY AND MEDICINE

Programmed Cell Death Initiation and Execution in Budding Yeast

(2015) Randy Strich   GENETICS

Oxidative Modification of miR-184 Enables It to Target Bcl-xL and Bcl-w

(2015) Jian-Xun Wang et al.   MOLECULAR CELL

Resveratrol up-regulates AMPA receptor expression via AMP-activated protein kinase-mediated protein translation

(2015) Guan Wang et al.   NEUROPHARMACOLOGY

Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer Progression

(2015) Jelena Krstić et al.   Oxidative Medicine and Cellular Longevity

Stabilization of the G-quadruplex at the VEGF IRES represses cap-independent translation

(2015) Anne Cammas et al.   RNA Biology

Codon-biased translation can be regulated by wobble-base tRNA modification systems during cellular stress responses

(2015) Lauren Endres et al.   RNA Biology

Programmed Cell Death Initiation and Execution in Budding Yeast

(2015) Randy Strich   GENETICS

Reciprocal regulation of TGF-β and reactive oxygen species: A perverse cycle for fibrosis

(2015) Rui-Ming Liu et al.   Redox Biology

Exploring Internal Ribosome Entry Sites as Therapeutic Targets

(2015) Anton A. Komar et al.   Frontiers in Oncology

Upstream open reading frame in 5′-untranslated region reduces titin mRNA translational efficiency

(2014) Adrian G. Cadar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural Changes Enable Start Codon Recognition by the Eukaryotic Translation Initiation Complex

(2014) Tanweer Hussain et al.   CELL

Double-Stranded RNA–Dependent Protein Kinase Deficiency Protects the Heart From Systolic Overload-Induced Congestive Heart Failure

(2014) Huan Wang et al.   CIRCULATION

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Endoplasmic Reticulum Stress Sensor Protein Kinase R–Like Endoplasmic Reticulum Kinase (PERK) Protects Against Pressure Overload–Induced Heart Failure and Lung Remodeling

(2014) Xiaoyu Liu et al.   HYPERTENSION

Vascular Endothelial Growth Factor Signaling in Hypoxia and Inflammation

(2014) S. Ramakrishnan et al.   Journal of Neuroimmune Pharmacology

An Active Role for the Ribosome in Determining the Fate of Oxidized mRNA

(2014) Carrie L. Simms et al.   Cell Reports

Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function

(2014) Anas Khawaja et al.   Wiley Interdisciplinary Reviews-RNA

Molecular and Functional Alterations in a Mouse Cardiac Model of Friedreich Ataxia

(2013) Michael Li-Hsuan Huang et al.   AMERICAN JOURNAL OF PATHOLOGY

Hypoxia-Inducible Factor 1 and Cardiovascular Disease

(2013) Gregg L. Semenza   Annual Review of Physiology

The eIF2α kinases: their structures and functions

(2013) Neysan Donnelly et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Loss of the Eukaryotic Initiation Factor 2α Kinase General Control Nonderepressible 2 Protects Mice From Pressure Overload–Induced Congestive Heart Failure Without Affecting Ventricular Hypertrophy

(2013) Zhongbing Lu et al.   HYPERTENSION

Rheb (Ras Homologue Enriched in Brain)-dependent Mammalian Target of Rapamycin Complex 1 (mTORC1) Activation Becomes Indispensable for Cardiac Hypertrophic Growth after Early Postnatal Period

(2013) Takahito Tamai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiac Titin and Heart Disease

(2013) Martin M. LeWinter et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury

(2013) Vincent Braunersreuther et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Vascular endothelial growth factor in heart failure

(2013) Ziad Taimeh et al.   Nature Reviews Cardiology

Mechanistic Target of Rapamycin (Mtor) Is Essential for Murine Embryonic Heart Development and Growth

(2013) Yi Zhu et al.   PLoS One

Increased Mammalian Lifespan and a Segmental and Tissue-Specific Slowing of Aging after Genetic Reduction of mTOR Expression

(2013) J. Julie Wu et al.   Cell Reports

Sites of reactive oxygen species generation by mitochondria oxidizing different substrates

(2013) Casey L. Quinlan et al.   Redox Biology

Ribosomal Protein L17, RpL17, is an Inhibitor of Vascular Smooth Muscle Growth and Carotid Intima Formation

(2012) Elaine M. Smolock et al.   CIRCULATION

Direct and Indirect Involvement of MicroRNA-499 in Clinical and Experimental Cardiomyopathy

(2012) Scot J. Matkovich et al.   CIRCULATION RESEARCH

RNA oxidation catalyzed by cytochrome c leads to its depurination and cross-linking, which may facilitate cytochrome c release from mitochondria

(2012) Mikiei Tanaka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Eukaryotic Initiation Factor 2 Phosphorylation and Translational Control in Metabolism

(2012) Thomas D. Baird et al.   Advances in Nutrition

Oxidative stress and heart failure

(2011) Hiroyuki Tsutsui et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Superoxide Dismutases: Role in Redox Signaling, Vascular Function, and Diseases

(2011) Tohru Fukai et al.   ANTIOXIDANTS & REDOX SIGNALING

Structural Instability and Cu-Dependent Pro-Oxidant Activity Acquired by the Apo Form of Mutant SOD1 Associated with Amyotrophic Lateral Sclerosis

(2011) Furi Kitamura et al.   BIOCHEMISTRY

Mitonuclear match: Optimizing fitness and fertility over generations drives ageing within generations

(2011) Nick Lane   BIOESSAYS

Small Nucleolar RNAs U32a, U33, and U35a Are Critical Mediators of Metabolic Stress

(2011) Carlos I. Michel et al.   Cell Metabolism

Unraveling the Biological Roles of Reactive Oxygen Species

(2011) Michael P. Murphy et al.   Cell Metabolism

tRNA structural and functional changes induced by oxidative stress

(2011) Barbara Nawrot et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Therapeutic Inhibition of miR-208a Improves Cardiac Function and Survival During Heart Failure

(2011) Rusty L. Montgomery et al.   CIRCULATION

Reactive Oxygen Species in Myocardial Reperfusion Injury: From Physiopathology to Therapeutic Approaches

(2011) Vincent Braunersreuther et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Cardiomyopathy Is Associated with Ribosomal Protein Gene Haplo-Insufficiency inDrosophila melanogaster

(2011) Michelle E. Casad et al.   GENETICS

Saffold Virus, a Novel Human Cardiovirus with Unknown Pathogenicity

(2011) T. Himeda et al.   JOURNAL OF VIROLOGY

MicroRNA-1 and -499 Regulate Differentiation and Proliferation in Human-Derived Cardiomyocyte Progenitor Cells

(2010) Joost P.G. Sluijter et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The sites and topology of mitochondrial superoxide production

(2010) Martin D. Brand   EXPERIMENTAL GERONTOLOGY

Mechanism of eIF6-mediated Inhibition of Ribosomal Subunit Joining

(2010) Marco Gartmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Viral Myocarditis

(2009) Toshitaka Yajima et al.   CIRCULATION

A novel class of small RNAs: tRNA-derived RNA fragments (tRFs)

(2009) Yong Sun Lee et al.   GENES & DEVELOPMENT

Angiogenin cleaves tRNA and promotes stress-induced translational repression

(2009) Satoshi Yamasaki et al.   JOURNAL OF CELL BIOLOGY

MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice

(2009) Thomas E. Callis et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardioviruses Are Genetically Diverse and Cause Common Enteric Infections in South Asian Children

(2009) O. Blinkova et al.   JOURNAL OF VIROLOGY

Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans

(2009) S. E. Calvo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Saffold Virus, a Human Theiler's-Like Cardiovirus, Is Ubiquitous and Causes Infection Early in Life

(2009) Jan Zoll et al.   PLoS Pathogens

Antioxidant Gene Therapy for Cardiovascular Disease

(2008) Anna-Liisa Levonen et al.   CIRCULATION

An upstream open reading frame within an IRES controls expression of a specific VEGF-A isoform

(2008) Amandine Bastide et al.   NUCLEIC ACIDS RESEARCH

Quantifying changes in the thiol redox proteome upon oxidative stress in vivo

(2008) L. I. Leichert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Vilyuisk encephalitis

(2008) Howard L. Lipton   REVIEWS IN MEDICAL VIROLOGY

Activating transcription factor 4

(2007) Kurosh Ameri et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY