Vascular endothelial growth factor in heart failure

VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond

(2012) M Giacca et al.   GENE THERAPY

Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial

(2012) Raj R Makkar et al.   LANCET

AAV9-mediated VEGF-B Gene Transfer Improves Systolic Function in Progressive Left Ventricular Hypertrophy

(2012) Jenni Huusko et al.   MOLECULAR THERAPY

Suicide Gene Reveals the Myocardial Neovascularization Role of Mesenchymal Stem Cells Overexpressing CXCR4 (MSCCXCR4)

(2012) Jialiang Liang et al.   PLoS One

Adipose-derived mesenchymal stromal cells for chronic myocardial ischemia (MyStromalCell Trial): study design

(2012) Abbas Ali Qayyum et al.   Regenerative Medicine

Tissue Inhibitor of Matrix Metalloproteinase-3 or Vascular Endothelial Growth Factor Transfection of Aged Human Mesenchymal Stem Cells Enhances Cell Therapy after Myocardial Infarction

(2012) Jie Yao et al.   REJUVENATION RESEARCH

Activation of Diverse Signaling Pathways by Ex-Vivo Delivery of Multiple Cytokines for Myocardial Repair

(2012) Mikhail Konoplyannikov et al.   STEM CELLS AND DEVELOPMENT

Controlled Angiogenesis in the Heart by Cell-Based Expression of Specific Vascular Endothelial Growth Factor Levels

(2012) Ludovic F. Melly et al.   Human Gene Therapy Methods

Intramyocardial plasmid-encoding human vascular endothelial growth factor A165/basic fibroblast growth factor therapy using percutaneous transcatheter approach in patients with refractory coronary artery disease (VIF-CAD)

(2011) Krzysztof Kukuła et al.   AMERICAN HEART JOURNAL

Cardiac pressure overload hypertrophy is differentially regulated by β-adrenergic receptor subtypes

(2011) Mingming Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

VEGF/SDF-1 promotes cardiac stem cell mobilization and myocardial repair in the infarcted heart

(2011) Jun-Ming Tang et al.   CARDIOVASCULAR RESEARCH

Placental Growth Factor Regulates Cardiac Inflammation Through the Tissue Inhibitor of Metalloproteinases-3/Tumor Necrosis Factor-α–Converting Enzyme Axis

(2011) Daniela Carnevale et al.   CIRCULATION

Role of Cardiac Stem Cells in Cardiac Pathophysiology: A Paradigm Shift in Human Myocardial Biology

(2011) Annarosa Leri et al.   CIRCULATION RESEARCH

Endothelial progenitor cell transplantation decreases lymphangiogenesis and adverse myocardial remodeling in a mouse model of acute myocardial infarction

(2011) Jae-Hyeong Park et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats: the critical role of ASK1 and VEGF

(2011) Hisato Nako et al.   HYPERTENSION RESEARCH

VEGF attenuates development from cardiac hypertrophy to heart failure after aortic stenosis through mitochondrial mediated apoptosis and cardiomyocyte proliferation

(2011) Xiao H Xu et al.   Journal of Cardiothoracic Surgery

Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial

(2011) Roberto Bolli et al.   LANCET

Hypoxia-inducible Vascular Endothelial Growth Factor-engineered Mesenchymal Stem Cells Prevent Myocardial Ischemic Injury

(2011) Sun Hwa Kim et al.   MOLECULAR THERAPY

Coexpression of VEGF and angiopoietin-1 promotes angiogenesis and cardiomyocyte proliferation reduces apoptosis in porcine myocardial infarction (MI) heart

(2011) Zhengxian Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A randomised, double-blind, placebo-controlled, multicentre study of the safety and efficacy of BIOBYPASS (AdGVVEGF121.10NH) gene therapy in patients with refractory advanced coronary artery disease: the NOVA trial

(2011) Jens Kastrup et al.   EuroIntervention

Adrenergic Receptor Blockade Reverses Right Heart Remodeling and Dysfunction in Pulmonary Hypertensive Rats

(2010) Harm J. Bogaard et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Vascular endothelial growth factor-B gene transfer prevents angiotensin II-induced diastolic dysfunction via proliferation and capillary dilatation in rats

(2010) Raisa Serpi et al.   CARDIOVASCULAR RESEARCH

Intramyocardial VEGF-B 167 Gene Delivery Delays the Progression Towards Congestive Failure in Dogs With Pacing-Induced Dilated Cardiomyopathy

(2010) Martino Pepe et al.   CIRCULATION RESEARCH

Relative Roles of Direct Regeneration Versus Paracrine Effects of Human Cardiosphere-Derived Cells Transplanted Into Infarcted Mice

(2010) Isotta Chimenti et al.   CIRCULATION RESEARCH

Norepinephrine induces VEGF expression and angiogenesis by a hypoxia-inducible factor-1α protein-dependent mechanism

(2010) Soon Young Park et al.   INTERNATIONAL JOURNAL OF CANCER

Guided Cardiopoiesis Enhances Therapeutic Benefit of Bone Marrow Human Mesenchymal Stem Cells in Chronic Myocardial Infarction

(2010) Atta Behfar et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A novel mechanism for endothelial progenitor cells homing: The SDF-1/CXCR4–Rac pathway may regulate endothelial progenitor cells homing through cellular polarization

(2010) Li Shen et al.   MEDICAL HYPOTHESES

Cell therapy for the treatment of coronary heart disease: a critical appraisal

(2010) Kai C. Wollert et al.   Nature Reviews Cardiology

Transplantation with survivin-engineered mesenchymal stem cells results in better prognosis in a rat model of myocardial infarction

(2009) Lin Fan et al.   EUROPEAN JOURNAL OF HEART FAILURE

Vascular endothelial growth factor promotes cardiac stem cell migration via the PI3K/Akt pathway

(2009) Junming Tang et al.   EXPERIMENTAL CELL RESEARCH

Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction

(2009) Lorena Zentilin et al.   FASEB JOURNAL

VEGF Gene Therapy Fails to Improve Perfusion of Ischemic Myocardium in Patients With Advanced Coronary Disease: Results of the NORTHERN Trial

(2009) Duncan J Stewart et al.   MOLECULAR THERAPY

VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis

(2009) F. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reevaluation of the Role of VEGF-B Suggests a Restricted Role in the Revascularization of the Ischemic Myocardium

(2008) Xuri Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Molecular Mechanisms Underlying the Transition of Cardiac Hypertrophy to Heart Failure

(2008) Toru Oka et al.   CIRCULATION JOURNAL

Overexpression of Vascular Endothelial Growth Factor-B in Mouse Heart Alters Cardiac Lipid Metabolism and Induces Myocardial Hypertrophy

(2008) Terhi Karpanen et al.   CIRCULATION RESEARCH

Paracrine Mechanisms in Adult Stem Cell Signaling and Therapy

(2008) Massimiliano Gnecchi et al.   CIRCULATION RESEARCH

Elevation of plasma placental growth factor in the patients with ischemic cardiomyopathy

(2008) Tomohiro Nakamura et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Mesenchymal stem cells and cardiac repair

(2008) Catharina Nesselmann et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Bones of contention: Marrow-derived cells in myocardial regeneration

(2008) Mark A. Sussman et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Beneficial effects of prolonged systemic administration of PlGF on late outcome of post-ischaemic myocardial performance

(2008) C Roncal et al.   JOURNAL OF PATHOLOGY