MicroRNA regulation of macrophages in human pathologies

Monocyte and Macrophage Plasticity in Tissue Repair and Regeneration

(2015) Amitava Das et al.   AMERICAN JOURNAL OF PATHOLOGY

A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome

(2015) Bastian Fromm et al.   Annual Review of Genetics

Regulation ofCsf1randBcl6in Macrophages Mediates the Stage-Specific Effects of MicroRNA-155 on AtherosclerosisSignificance

(2015) Yuanyuan Wei et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of lipid microdomains in TLR-mediated signalling

(2015) Jean-Marie Ruysschaert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Altered lymphopoiesis and immunodeficiency in miR-142 null mice

(2015) N. J. Kramer et al.   BLOOD

Colony stimulating factor-1 receptor signaling networks inhibit mouse macrophage inflammatory responses by induction of microRNA-21

(2015) C. I. Caescu et al.   BLOOD

Endothelial cells suppress monocyte activation through secretion of extracellular vesicles containing antiinflammatory microRNAs

(2015) M.-S. Njock et al.   BLOOD

MicroRNA let-7 Modulates the Immune Response to Mycobacterium tuberculosis Infection via Control of A20, an Inhibitor of the NF-κB Pathway

(2015) Manish Kumar et al.   Cell Host & Microbe

Macrophage polarization in pathology

(2015) Antonio Sica et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Early Secreted Antigen ESAT-6 of Mycobacterium Tuberculosis Promotes Apoptosis of Macrophages via Targeting the MicroRNA155-SOCS1 Interaction

(2015) Shaojun Yang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

MicroRNA-155 Exerts Cell-Specific Antiangiogenic but Proarteriogenic Effects During Adaptive NeovascularizationCLINICAL PERSPECTIVE

(2015) Franziska Pankratz et al.   CIRCULATION

Apolipoprotein E Enhances MicroRNA-146a in Monocytes and Macrophages to Suppress Nuclear Factor- B-Driven Inflammation and Atherosclerosis

(2015) K. Li et al.   CIRCULATION RESEARCH

Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and Is Enhanced by Anti-miR33 in AtherosclerosisNovelty and Significance

(2015) Denuja Karunakaran et al.   CIRCULATION RESEARCH

MicroRNAs and the response to injury in atherosclerosis

(2015) L. Natarelli et al.   Hamostaseologie

Endothelial Hypoxia-Inducible Factor-1α Promotes Atherosclerosis and Monocyte Recruitment by Upregulating MicroRNA-19a

(2015) Shamima Akhtar et al.   HYPERTENSION

Epidermal Fatty Acid Binding Protein Promotes Skin Inflammation Induced by High-Fat Diet

(2015) Yuwen Zhang et al.   IMMUNITY

A Single miRNA-mRNA Interaction Affects the Immune Response in a Context- and Cell-Type-Specific Manner

(2015) Li-Fan Lu et al.   IMMUNITY

Negative regulation of TLR signaling in myeloid cells-implications for autoimmune diseases

(2015) Jessica A. Hamerman et al.   IMMUNOLOGICAL REVIEWS

Apoptotic cell recognition receptors and scavenger receptors

(2015) Kristen K. Penberthy et al.   IMMUNOLOGICAL REVIEWS

Delivery of microRNA-146a with polyethylenimine nanoparticles inhibits renal fibrosis in vivo

(2015) Yoshiyuki Morishita et al.   International Journal of Nanomedicine

Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1

(2015) Aaron M. Fond et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation

(2015) Wei Ying et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-33–dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

(2015) Mireille Ouimet et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-24, miR-30b, and miR-142-3p Regulate Phagocytosis in Myeloid Inflammatory Cells

(2015) Afsar Raza Naqvi et al.   JOURNAL OF IMMUNOLOGY

Interleukin 1�-Responsive MicroRNA-146a Is Critical for the Cytokine-Induced Tolerance and Cross-Tolerance to Toll-Like Receptor Ligands

(2015) Md A. Nahid et al.   Journal of Innate Immunity

Regulation of miR-24, miR-30b, and miR-142-3p during macrophage and dendritic cell differentiation potentiates innate immunity

(2015) Jezrom B. Fordham et al.   JOURNAL OF LEUKOCYTE BIOLOGY

miR-223 is upregulated in monocytes from patients with tuberculosis and regulates function of monocyte-derived macrophages

(2015) Yanhua Liu et al.   MOLECULAR IMMUNOLOGY

Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation

(2015) Xiaodi Su et al.   NATURE IMMUNOLOGY

Phagocytosis of apoptotic cells in homeostasis

(2015) Sanja Arandjelovic et al.   NATURE IMMUNOLOGY

Control of adaptive immunity by the innate immune system

(2015) Akiko Iwasaki et al.   NATURE IMMUNOLOGY

MicroRNA-mediated mechanisms of the cellular stress response in atherosclerosis

(2015) Andreas Schober et al.   Nature Reviews Cardiology

Generation and Validation of miR-142 Knock Out Mice

(2015) Amit Shrestha et al.   PLoS One

Model-guided quantitative analysis of microRNA-mediated regulation on competing endogenous RNAs using a synthetic gene circuit

(2015) Ye Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA

(2015) Gaspare La Rocca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA control of protein expression noise

(2015) J. M. Schmiedel et al.   SCIENCE

miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program

(2015) Shicheng Su et al.   Nature Communications

A double feedback loop mediated by microRNA-23a/27a/24-2 regulates M1 versus M2 macrophage polarization and thus regulates cancer progression

(2015) Sisi Ma et al.   Oncotarget

Regulation rewiring analysis reveals mutual regulation between STAT1 and miR-155-5p in tumor immunosurveillance in seven major cancers

(2015) Chen-Ching Lin et al.   Scientific Reports

The miR-302/367 cluster: a comprehensive update on its evolution and functions

(2015) Zeqian Gao et al.   Open Biology

Biogenesis and regulation of the let-7 miRNAs and their functional implications

(2015) Hosuk Lee et al.   Protein & Cell

Current Concept and Update of the Macrophage Plasticity Concept: Intracellular Mechanisms of Reprogramming and M3 Macrophage “Switch” Phenotype

(2015) Igor Malyshev et al.   Biomed Research International

A Hitchhiker’s Guide to Myeloid Cell Subsets: Practical Implementation of a Novel Mononuclear Phagocyte Classification System

(2015) Martin Guilliams et al.   Frontiers in Immunology

The Many Alternative Faces of Macrophage Activation

(2015) David A. Hume   Frontiers in Immunology

MicroRNA-21, induced by high glucose, modulates macrophage apoptosis via programmed cell death 4

(2015) YUAN-YUAN SHANG et al.   Molecular Medicine Reports

Kruppel-Like Factor 2-Mediated Suppression of MicroRNA-155 Reduces the Proinflammatory Activation of Macrophages

(2015) Shaolin He et al.   PLoS One

MicroRNA-155 Deficiency Results in Decreased Macrophage Inflammation and Attenuated Atherogenesis in Apolipoprotein E–Deficient Mice

(2014) Fen Du et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNA-27a/b regulates cellular cholesterol efflux, influx and esterification/hydrolysis in THP-1 macrophages

(2014) Min Zhang et al.   ATHEROSCLEROSIS

MicroRNA-19b promotes macrophage cholesterol accumulation and aortic atherosclerosis by targeting ATP-binding cassette transporter A1

(2014) Yun-Cheng Lv et al.   ATHEROSCLEROSIS

miR-223: An inflammatory oncomiR enters the cardiovascular field

(2014) Fatiha Taïbi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Elevated microRNA-155 promotes foam cell formation by targeting HBP1 in atherogenesis

(2014) Fu-Ju Tian et al.   CARDIOVASCULAR RESEARCH

Polycomb-mediated loss of microRNA let-7c determines inflammatory macrophage polarization via PAK1-dependent NF-κB pathway

(2014) W Zhang et al.   CELL DEATH AND DIFFERENTIATION

Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling

(2014) Agnieszka Płóciennikowska et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MicroRNA-21 is a unique signature associated with coronary plaque instability in humans by regulating matrix metalloproteinase-9 via reversion-inducing cysteine-rich protein with Kazal motifs

(2014) Xuesong Fan et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

Macrophages, Immunity, and Metabolic Disease

(2014) Joanne C. McNelis et al.   IMMUNITY

CXCL4-induced plaque macrophages can be specifically identified by co-expression of MMP7+S100A8+in vitro and in vivo

(2014) Christian Erbel et al.   Innate Immunity

Cholesterol-Rich Membrane Rafts and Lyn Are Involved in Phagocytosis during Pseudomonas aeruginosa Infection

(2014) S. Kannan et al.   JOURNAL OF IMMUNOLOGY

Engulfment of Apoptotic Cells by Macrophages: A Role of MicroRNA-21 in the Resolution of Wound Inflammation

(2014) A. Das et al.   JOURNAL OF IMMUNOLOGY

Macrophage PTEN Regulates Expression and Secretion of Arginase I Modulating Innate and Adaptive Immune Responses

(2014) Emine Sahin et al.   JOURNAL OF IMMUNOLOGY

IFN-γ Primes Macrophage Activation by Increasing Phosphatase and Tensin Homolog via Downregulation of miR-3473b

(2014) Cong Wu et al.   JOURNAL OF IMMUNOLOGY

miR-27a Regulates Inflammatory Response of Macrophages by Targeting IL-10

(2014) N. Xie et al.   JOURNAL OF IMMUNOLOGY

miR-199a-5p inhibits monocyte/macrophage differentiation by targeting the activin A type 1B receptor gene and finally reducing C/EBPα expression

(2014) Hai-Shuang Lin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Macrophage deficiency of Akt2 reduces atherosclerosis inLdlrnull mice

(2014) Vladimir R. Babaev et al.   JOURNAL OF LIPID RESEARCH

Mitochondrial metabolism, reactive oxygen species, and macrophage function-fishing for insights

(2014) Christopher J. Hall et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The microRNA-146a/b attenuates acute small-for-size liver graft injury in rats

(2014) Weiwei Jiang et al.   LIVER INTERNATIONAL

Endogenous miRNA and Target Concentrations Determine Susceptibility to Potential ceRNA Competition

(2014) Andrew D. Bosson et al.   MOLECULAR CELL

mRNA Destabilization Is the Dominant Effect of Mammalian MicroRNAs by the Time Substantial Repression Ensues

(2014) Stephen W. Eichhorn et al.   MOLECULAR CELL

Metabolism of stromal and immune cells in health and disease

(2014) Bart Ghesquière et al.   NATURE

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

(2014) Stanley Ching-Cheng Huang et al.   NATURE IMMUNOLOGY

Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

(2014) Jan Mauer et al.   NATURE IMMUNOLOGY

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

(2014) Calum C Bain et al.   NATURE IMMUNOLOGY

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth

(2014) H Mathsyaraja et al.   ONCOGENE

An Agomir of miR-144-3p Accelerates Plaque Formation through Impairing Reverse Cholesterol Transport and Promoting Pro-Inflammatory Cytokine Production

(2014) Yan-Wei Hu et al.   PLoS One

MiR-143/145 deficiency attenuates the progression of atherosclerosis in Ldlr-/- mice

(2014) Federica Sala et al.   THROMBOSIS AND HAEMOSTASIS

CSF-1 Receptor Signaling in Myeloid Cells

(2014) E. R. Stanley et al.   Cold Spring Harbor Perspectives in Biology

MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo

(2014) Takahiro Horie et al.   Scientific Reports

Endogenous RNAs Modulate MicroRNA Sorting to Exosomes and Transfer to Acceptor Cells

(2014) Mario Leonardo Squadrito et al.   Cell Reports

From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation

(2014) Paola Italiani et al.   Frontiers in Immunology

Phenotypic Transitions of Macrophages Orchestrate Tissue Repair

(2013) Margaret L. Novak et al.   AMERICAN JOURNAL OF PATHOLOGY

Pathogenic arterial remodeling: the good and bad of microRNAs

(2013) Yuanyuan Wei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Molecular Mechanisms of RNA Interference

(2013) Ross C. Wilson et al.   Annual Review of Biophysics

Transcriptional Control of Macrophage Polarization

(2013) Derin Tugal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNA-126, -145, and -155

(2013) Yuanyuan Wei et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A role for miR-142-3p in colony-stimulating factor 1-induced monocyte differentiation into macrophages

(2013) Brice Lagrange et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding

(2013) Aleksandra Helwak et al.   CELL

The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

(2013) E Mogilyansky et al.   CELL DEATH AND DIFFERENTIATION

Impaired Cholesterol Efflux in Senescent Macrophages Promotes Age-Related Macular Degeneration

(2013) Abdoulaye Sene et al.   Cell Metabolism

Immunoresponsive Gene 1 Augments Bactericidal Activity of Macrophage-Lineage Cells by Regulating β-Oxidation-Dependent Mitochondrial ROS Production

(2013) Christopher J. Hall et al.   Cell Metabolism

MicroRNA-let-7a promotes E2F-mediated cell proliferation and NFκB activation in vitro

(2013) Cristen B Chafin et al.   Cellular & Molecular Immunology

The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1- and microRNA-155 –Dependent Pathway During Atherosclerosis

(2013) Yuanyuan Wei et al.   CIRCULATION

Control of Cholesterol Metabolism and Plasma High-Density Lipoprotein Levels by microRNA-144

(2013) Cristina M. Ramírez et al.   CIRCULATION RESEARCH

Changes in macrophage phenotype as the immune response evolves

(2013) Julia Lichtnekert et al.   CURRENT OPINION IN PHARMACOLOGY

miR-142-3p Prevents Macrophage Differentiation during Cancer-Induced Myelopoiesis

(2013) Nada Sonda et al.   IMMUNITY

Metabolic Pathways in Immune Cell Activation and Quiescence

(2013) Erika L. Pearce et al.   IMMUNITY

MiR-146a Regulates IL-6 Production in Lipopolysaccharide-Induced RAW264.7 Macrophage Cells by Inhibiting Notch1

(2013) Yong He et al.   INFLAMMATION

MicroRNAs responsive to Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis LPS modulate expression of genes regulating innate immunity in human macrophages

(2013) Afsar R Naqvi et al.   Innate Immunity

Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: Correlation of CD163 expression, cytokine levels and early relapse

(2013) Silke Reinartz et al.   INTERNATIONAL JOURNAL OF CANCER

The Role of Ets2 Transcription Factor in the Induction of MicroRNA-155 (miR-155) by Lipopolysaccharide and Its Targeting by Interleukin-10

(2013) Susan R. Quinn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA let-7c Regulates Macrophage Polarization

(2013) S. Banerjee et al.   JOURNAL OF IMMUNOLOGY

Akt2 Deficiency Protects from Acute Lung Injury via Alternative Macrophage Activation and miR-146a Induction in Mice

(2013) E. Vergadi et al.   JOURNAL OF IMMUNOLOGY

PU.1-Dependent Transcriptional Regulation of miR-142 Contributes to Its Hematopoietic Cell-Specific Expression and Modulation of IL-6

(2013) Y. Sun et al.   JOURNAL OF IMMUNOLOGY

miR-155 inhibits oxidized low-density lipoprotein-induced apoptosis of RAW264.7 cells

(2013) Guo-fu Zhu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

M-CSF instructs myeloid lineage fate in single haematopoietic stem cells

(2013) Noushine Mossadegh-Keller et al.   NATURE

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Next-generation sequencing of microRNAs uncovers expression signatures in polarized macrophages

(2013) Viviana Cobos Jiménez et al.   PHYSIOLOGICAL GENOMICS

Antagonism of Betulinic Acid on LPS-Mediated Inhibition of ABCA1 and Cholesterol Efflux through Inhibiting Nuclear Factor-kappaB Signaling Pathway and miR-33 Expression

(2013) Guo-Jun Zhao et al.   PLoS One

MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice

(2013) Takahiro Horie et al.   Nature Communications

FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4

(2013) Kuppusamy Balamurugan et al.   Nature Communications

miRNAs confer phenotypic robustness to gene networks by suppressing biological noise

(2013) Velia Siciliano et al.   Nature Communications

Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation

(2013) Luke C. Davies et al.   Nature Communications

Actin-binding protein regulation by microRNAs as a novel microbial strategy to modulate phagocytosis by host cells: the case of N-Wasp and miR-142-3p

(2013) Paulo Bettencourt et al.   Frontiers in Cellular and Infection Microbiology

Temporal dynamics and transcriptional control using single-cell gene expression analysis

(2013) Tsukasa Kouno et al.   GENOME BIOLOGY

MicroRNA‐33 Deficiency Reduces the Progression of Atherosclerotic Plaque in ApoE −/− Mice

(2013) Takahiro Horie et al.   Journal of the American Heart Association

Lipid Droplets and Cellular Lipid Metabolism

(2012) Tobias C. Walther et al.   Annual Review of Biochemistry

Myeloid Krüppel-Like Factor 4 Deficiency Augments Atherogenesis in ApoE −/− Mice—Brief Report

(2012) Nikunj Sharma et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Macrophage microvesicles induce macrophage differentiation and miR-223 transfer

(2012) N. Ismail et al.   BLOOD

Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses

(2012) Nathanael J. Spann et al.   CELL

Roles for MicroRNAs in Conferring Robustness to Biological Processes

(2012) Margaret S. Ebert et al.   CELL

Regulation of C/EBPβ and resulting functions in cells of the monocytic lineage

(2012) René Huber et al.   CELLULAR SIGNALLING

A Novel Regulator of Macrophage Activation

(2012) Guoqing Zhuang et al.   CIRCULATION

CSF-1 signaling in macrophages: pleiotrophy through phosphotyrosine-based signaling pathways

(2012) Kellie A. Mouchemore et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype

(2012) Larissa Cardilo-Reis et al.   EMBO Molecular Medicine

Identifying Functional MicroRNAs in Macrophages with Polarized Phenotypes

(2012) Joel W. Graff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages

(2012) Maliheh Nazari-Jahantigh et al.   JOURNAL OF CLINICAL INVESTIGATION

Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

(2012) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

NLRP3 Inflammasome Activity Is Negatively Controlled by miR-223

(2012) F. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: miR-223 and EBV miR-BART15 Regulate the NLRP3 Inflammasome and IL-1  Production

(2012) M. Haneklaus et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-21 (miR-21) expression promotes growth, metastasis, and chemo- or radioresistance in non-small cell lung cancer cells by targeting PTEN

(2012) Zhi-Li Liu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Tumor Suppressor PDCD4 Represses Internal Ribosome Entry Site-Mediated Translation of Antiapoptotic Proteins and Is Regulated by S6 Kinase 2

(2012) U. Liwak et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR

(2012) Anna C. Calkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The N domain of Argonaute drives duplex unwinding during RISC assembly

(2012) Pieter Bas Kwak et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A miR-19 regulon that controls NF-κB signaling

(2012) Michael P. Gantier et al.   NUCLEIC ACIDS RESEARCH

Hematopoietic miR155 Deficiency Enhances Atherosclerosis and Decreases Plaque Stability in Hyperlipidemic Mice

(2012) Marjo M. P. C. Donners et al.   PLoS One

Inducible MicroRNA-223 Down-Regulation Promotes TLR-Triggered IL-6 and IL-1β Production in Macrophages by Targeting STAT3

(2012) Qingyun Chen et al.   PLoS One

Induction of microRNA-155 is TLR- and type IV secretion system-dependent in macrophages and inhibits DNA-damage induced apoptosis

(2012) M. Koch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization

(2012) A. Arranz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Mitochondrial oxidative stress and the metabolic syndrome

(2012) Andrew M. James et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Crosstalk between reverse cholesterol transport and innate immunity

(2012) Kathleen M. Azzam et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Colony stimulating factors and myeloid cell biology in health and disease

(2012) John A. Hamilton et al.   TRENDS IN IMMUNOLOGY

miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study

(2011) Emma Raitoharju et al.   ATHEROSCLEROSIS

Targeting of microRNA-142-3p in dendritic cells regulates endotoxin-induced mortality

(2011) Y. Sun et al.   BLOOD

Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers

(2011) E. Sierra-Filardi et al.   BLOOD

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

The transcriptional regulation of miR-21, its multiple transcripts and their implication in prostate cancer

(2011) Judit Ribas et al.   CELL CYCLE

Oxidation-Specific Epitopes Are Danger-Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity

(2011) Yury I. Miller et al.   CIRCULATION RESEARCH

Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis

(2011) Anouk A.J. Hamers et al.   CIRCULATION RESEARCH

NR4A1 (Nur77) Deletion Polarizes Macrophages Toward an Inflammatory Phenotype and Increases Atherosclerosis

(2011) Richard N. Hanna et al.   CIRCULATION RESEARCH

Analysis of the host microRNA response toSalmonellauncovers the control of major cytokines by thelet-7family

(2011) Leon N Schulte et al.   EMBO JOURNAL

Macrophage heterogeneity and acute inflammation

(2011) Kate Liddiard et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cholesterol regulation of receptor-interacting protein 140 via microRNA-33 in inflammatory cytokine production

(2011) Ping-Chih Ho et al.   FASEB JOURNAL

The role of tristetraprolin in cancer and inflammation

(2011) Sandhya Sanduja   Frontiers in Bioscience-Landmark

Tumor Suppressor Protein Pdcd4 Inhibits Translation of p53 mRNA

(2011) Lena Wedeken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Krüppel-like factor 4 regulates macrophage polarization

(2011) Xudong Liao et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice

(2011) Mark P. Boldin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lipid Bodies in Inflammatory Cells

(2011) Rossana C. N. Melo et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Intracellular Lipid Flux and Membrane Microdomains as Organizing Principles in Inflammatory Cell Signaling

(2011) M. B. Fessler et al.   JOURNAL OF IMMUNOLOGY

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

Evolution of microRNA diversity and regulation in animals

(2011) Eugene Berezikov   NATURE REVIEWS GENETICS

Integrated MicroRNA-mRNA-Analysis of Human Monocyte Derived Macrophages upon Mycobacterium avium subsp. hominissuis Infection

(2011) Jutta Sharbati et al.   PLoS One

Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis

(2011) X. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SREBPs: metabolic integrators in physiology and metabolism

(2011) Tae-Il Jeon et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Metchnikoff's policemen: macrophages in development, homeostasis and regeneration

(2011) James A. Stefater et al.   TRENDS IN MOLECULAR MEDICINE

Inflammatory cytokines regulate microRNA-155 expression in human retinal pigment epithelial cells by activating JAK/STAT pathway

(2010) R. Krishnan Kutty et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Modulation of K-Ras-Dependent Lung Tumorigenesis by MicroRNA-21

(2010) Mark E. Hatley et al.   CANCER CELL

Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4

(2010) Y. Cheng et al.   CARDIOVASCULAR RESEARCH

Nonresolving Inflammation

(2010) Carl Nathan et al.   CELL

miR-223 and miR-142 attenuate hematopoietic cell proliferation and miR-223 positively regulates miR-142 through LMO2 isoforms and CEBP-β

(2010) Wei Sun et al.   CELL RESEARCH

ABCA1 and ABCG1 Protect Against Oxidative Stress–Induced Macrophage Apoptosis During Efferocytosis

(2010) Laurent Yvan-Charvet et al.   CIRCULATION RESEARCH

Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

(2010) Alexandra Kadl et al.   CIRCULATION RESEARCH

Cholesterol, the central lipid of mammalian cells

(2010) Frederick R Maxfield et al.   CURRENT OPINION IN CELL BIOLOGY

MicroRNA-27b Contributes to Lipopolysaccharide-mediated Peroxisome Proliferator-activated Receptor γ (PPARγ) mRNA Destabilization

(2010) Carla Jennewein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Up-regulation of MicroRNA-155 in Macrophages Contributes to Increased Tumor Necrosis Factor α (TNFα) Production via Increased mRNA Half-life in Alcoholic Liver Disease

(2010) Shashi Bala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXC Chemokine Ligand 4 Induces a Unique Transcriptome in Monocyte-Derived Macrophages

(2010) C. A. Gleissner et al.   JOURNAL OF IMMUNOLOGY

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

(2010) J.-C. Rodriguez-Prados et al.   JOURNAL OF IMMUNOLOGY

Estradiol Suppresses NF- B Activation through Coordinated Regulation of let-7a and miR-125b in Primary Human Macrophages

(2010) A. J. Murphy et al.   JOURNAL OF IMMUNOLOGY

Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol

(2010) Xuewei Zhu et al.   JOURNAL OF LIPID RESEARCH

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma

(2010) Pedro P. Medina et al.   NATURE

MicroRNAs modulate the noncanonical transcription factor NF-κB pathway by regulating expression of the kinase IKKα during macrophage differentiation

(2010) Tao Li et al.   NATURE IMMUNOLOGY

MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo

(2010) T. Horie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of fatty acid synthesis is a key requirement for phagocytic differentiation of human monocytes

(2010) Josef Ecker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

(2010) S. H. Najafi-Shoushtari et al.   SCIENCE

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

(2010) K. J. Rayner et al.   SCIENCE

Cell cholesterol homeostasis: Mediation by active cholesterol

(2010) Theodore L. Steck et al.   TRENDS IN CELL BIOLOGY

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Inflammation Impairs Reverse Cholesterol Transport In Vivo

(2009) Fiona C. McGillicuddy et al.   CIRCULATION

Notch1 upregulates LPS-induced macrophage activation by increasing NF-κB activity

(2009) Eva Monsalve et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Kinase Akt1 Controls Macrophage Response to Lipopolysaccharide by Regulating MicroRNAs

(2009) Ariadne Androulidaki et al.   IMMUNITY

MicroRNA-21 protects against the H2O2-induced injury on cardiac myocytes via its target gene PDCD4

(2009) Yunhui Cheng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Function of C/EBPδ in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals

(2009) Vladimir Litvak et al.   NATURE IMMUNOLOGY

Cholesterol depletion associated with Leishmania major infection alters macrophage CD40 signalosome composition and effector function

(2009) Abdur Rub et al.   NATURE IMMUNOLOGY

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

(2009) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

ATP-dependent human RISC assembly pathways

(2009) Mayuko Yoda et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural insights into RNA processing by the human RISC-loading complex

(2009) Hong-Wei Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Increased Cellular Free Cholesterol in Macrophage-specificAbca1Knock-out Mice Enhances Pro-inflammatory Response of Macrophages

(2008) Xuewei Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

(2008) Ryan M. O'Connell et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

The let-7 family of microRNAs

(2008) Sarah Roush et al.   TRENDS IN CELL BIOLOGY

Notch signaling is activated by TLR stimulation and regulates macrophage functions

(2007) Tanapat Palaga et al.   EUROPEAN JOURNAL OF IMMUNOLOGY