In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA

The RNA-binding Protein TDP-43 Selectively Disrupts MicroRNA-1/206 Incorporation into the RNA-induced Silencing Complex

(2014) Isabelle N. King et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mRNA Destabilization Is the Dominant Effect of Mammalian MicroRNAs by the Time Substantial Repression Ensues

(2014) Stephen W. Eichhorn et al.   MOLECULAR CELL

Landscape and variation of RNA secondary structure across the human transcriptome

(2014) Yue Wan et al.   NATURE

A-to-I editing in the miRNA seed region regulates target mRNA selection and silencing efficiency

(2014) Hideaki Kume et al.   NUCLEIC ACIDS RESEARCH

Loss of mTOR complex 1 induces developmental blockage in early T-lymphopoiesis and eradicates T-cell acute lymphoblastic leukemia cells

(2014) T. Hoshii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A bacterial seek-and-destroy system for foreign DNA

(2014) J. Vogel   SCIENCE

miRNA profiling of cancer

(2013) Gianpiero Di Leva et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

GW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylation

(2013) Latifa Zekri et al.   EMBO JOURNAL

Functionally Diverse MicroRNA Effector Complexes Are Regulated by Extracellular Signaling

(2013) Pei-Hsuan Wu et al.   MOLECULAR CELL

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Mechanistic Target of Rapamycin (Mtor) Is Essential for Murine Embryonic Heart Development and Growth

(2013) Yi Zhu et al.   PLoS One

Competition and collaboration between RNA-binding proteins and microRNAs

(2013) J. J. David Ho et al.   Wiley Interdisciplinary Reviews-RNA

Roles for MicroRNAs in Conferring Robustness to Biological Processes

(2012) Margaret S. Ebert et al.   CELL

Kinetic analysis reveals successive steps leading to miRNA-mediated silencing in mammalian cells

(2012) Julien Béthune et al.   EMBO REPORTS

A Critical Role for Rictor in T Lymphopoiesis

(2012) F. Tang et al.   JOURNAL OF IMMUNOLOGY

The microcosmos of cancer

(2012) Amaia Lujambio et al.   NATURE

Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes

(2012) Derrick Gibbings et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Long-lived microRNA-Argonaute complexes in quiescent cells can be activated to regulate mitogenic responses

(2012) S. H. Olejniczak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disease-linked microRNA-21 exhibits drastically reduced mRNA binding and silencing activity in healthy mouse liver

(2012) J. R. Androsavich et al.   RNA

The Crystal Structure of Human Argonaute2

(2012) N. T. Schirle et al.   SCIENCE

Deep-sequencing of human Argonaute-associated small RNAs provides insight into miRNA sorting and reveals Argonaute association with RNA fragments of diverse origin

(2011) Alexander Maxwell Burroughs et al.   RNA Biology

Making RISC

(2010) Tomoko Kawamata et al.   TRENDS IN BIOCHEMICAL SCIENCES

Ancestral Roles of Small RNAs: An Ago-Centric Perspective

(2010) L. Joshua-Tor et al.   Cold Spring Harbor Perspectives in Biology

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

(2008) M. Landthaler et al.   RNA