Regulation of microRNA biogenesis

Hippo Signaling Regulates Microprocessor and Links Cell-Density-Dependent miRNA Biogenesis to Cancer

(2014) Masaki Mori et al.   CELL

Inefficient SRP Interaction with a Nascent Chain Triggers a mRNA Quality Control Pathway

(2014) Andrey L. Karamyshev et al.   CELL

MeCP2 Suppresses Nuclear MicroRNA Processing and Dendritic Growth by Regulating the DGCR8/Drosha Complex

(2014) Tian-Lin Cheng et al.   DEVELOPMENTAL CELL

A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer

(2014) Yuan Tian et al.   MOLECULAR CELL

Processing of microRNA primary transcripts requires heme in mammalian cells

(2014) Sara H. Weitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosha-independent DGCR8/Pasha pathway regulates neuronal morphogenesis

(2014) A. Luhur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian 5′-Capped MicroRNA Precursors that Generate a Single MicroRNA

(2013) Mingyi Xie et al.   CELL

Beyond Secondary Structure: Primary-Sequence Determinants License Pri-miRNA Hairpins for Processing

(2013) Vincent C. Auyeung et al.   CELL

Selective Degradation of Host MicroRNAs by an Intergenic HCMV Noncoding RNA Accelerates Virus Production

(2013) Sanghyun Lee et al.   Cell Host & Microbe

Reciprocal Inhibition between Intracellular Antiviral Signaling and the RNAi Machinery in Mammalian Cells

(2013) Gil Ju Seo et al.   Cell Host & Microbe

A transient reversal of miRNA-mediated repression controls macrophage activation

(2013) Anup Mazumder et al.   EMBO REPORTS

T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire

(2013) Yelena Bronevetsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Akt-Mediated Phosphorylation of Argonaute 2 Downregulates Cleavage and Upregulates Translational Repression of MicroRNA Targets

(2013) Shane R. Horman et al.   MOLECULAR CELL

TDP-43 Regulates the Microprocessor Complex Activity During In Vitro Neuronal Differentiation

(2013) Valerio Di Carlo et al.   MOLECULAR NEUROBIOLOGY

A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28–let-7 pathway

(2013) Hao-Ming Chang et al.   NATURE

‘See-saw’ expression of microRNA-198 and FSTL1 from a single transcript in wound healing

(2013) Gopinath M. Sundaram et al.   NATURE

EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2

(2013) Jia Shen et al.   NATURE

Argonaute proteins: functional insights and emerging roles

(2013) Gunter Meister   NATURE REVIEWS GENETICS

Diversifying microRNA sequence and function

(2013) Stefan L. Ameres et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Homeostatic control of Argonaute stability by microRNA availability

(2013) Peter Smibert et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Substrate-specific structural rearrangements of human Dicer

(2013) David W Taylor et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

TALEN-based knockout library for human microRNAs

(2013) Young-Kook Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Microprocessor controls the activity of mammalian retrotransposons

(2013) Sara R Heras et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing

(2013) Ho Young Lee et al.   NUCLEIC ACIDS RESEARCH

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Acetylation of Drosha on the N-Terminus Inhibits Its Degradation by Ubiquitination

(2013) Xiaoli Tang et al.   PLoS One

Lower and upper stem-single-stranded RNA junctions together determine the Drosha cleavage site

(2013) H. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global microRNA elevation by inducible Exportin 5 regulates cell cycle entry

(2013) Y. W. Iwasaki et al.   RNA

Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs

(2013) D. Ustianenko et al.   RNA

Argonaute2 expression is post-transcriptionally coupled to microRNA abundance

(2013) N. J. Martinez et al.   RNA

Phosphorylation of DGCR8 Increases Its Intracellular Stability and Induces a Progrowth miRNA Profile

(2013) Kristina M. Herbert et al.   Cell Reports

DNA-Damage-Induced Nuclear Export of Precursor MicroRNAs Is Regulated by the ATM-AKT Pathway

(2013) Guohui Wan et al.   Cell Reports

Poly(A)-Specific Ribonuclease Mediates 3′-End Trimming of Argonaute2-Cleaved Precursor MicroRNAs

(2013) Mayuko Yoda et al.   Cell Reports

RNA Interference Pathways in Fungi: Mechanisms and Functions

(2012) Shwu-Shin Chang et al.   Annual Review of Microbiology

Eri1 regulates microRNA homeostasis and mouse lymphocyte development and antiviral function

(2012) M. F. Thomas et al.   BLOOD

Human RNA Methyltransferase BCDIN3D Regulates MicroRNA Processing

(2012) Blerta Xhemalce et al.   CELL

The Loop Position of shRNAs and Pre-miRNAs Is Critical for the Accuracy of Dicer Processing In Vivo

(2012) Shuo Gu et al.   CELL

Dicer Partner Proteins Tune the Length of Mature miRNAs in Flies and Mammals

(2012) Ryuya Fukunaga et al.   CELL

Mono-Uridylation of Pre-MicroRNA as a Key Step in the Biogenesis of Group II let-7 MicroRNAs

(2012) Inha Heo et al.   CELL

The Structure of Human Argonaute-2 in Complex with miR-20a

(2012) Elad Elkayam et al.   CELL

Degradation of Host MicroRNAs by Poxvirus Poly(A) Polymerase Reveals Terminal RNA Methylation as a Protective Antiviral Mechanism

(2012) Simone Backes et al.   Cell Host & Microbe

AGO4 Regulates Entry into Meiosis and Influences Silencing of Sex Chromosomes in the Male Mouse Germline

(2012) Andrew J. Modzelewski et al.   DEVELOPMENTAL CELL

Histone deacetylase 1 enhances microRNA processing via deacetylation of DGCR8

(2012) Taeko Wada et al.   EMBO REPORTS

Biology of PIWI-interacting RNAs: new insights into biogenesis and function inside and outside of germlines

(2012) H. Ishizu et al.   GENES & DEVELOPMENT

The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling

(2012) J. Chen et al.   GENES & DEVELOPMENT

Precursor MicroRNA-Programmed Silencing Complex Assembly Pathways in Mammals

(2012) Xuhang Liu et al.   MOLECULAR CELL

Structure of yeast Argonaute with guide RNA

(2012) Kotaro Nakanishi et al.   NATURE

Structure and function of Zucchini endoribonuclease in piRNA biogenesis

(2012) Hiroshi Nishimasu et al.   NATURE

The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis

(2012) Jonathan J. Ipsaro et al.   NATURE

The microcosmos of cancer

(2012) Amaia Lujambio et al.   NATURE

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors

(2012) Jun Xie et al.   NATURE METHODS

Drosha regulates neurogenesis by controlling Neurogenin 2 expression independent of microRNAs

(2012) Philip Knuckles et al.   NATURE NEUROSCIENCE

DGCR8 HITS-CLIP reveals novel functions for the Microprocessor

(2012) Sara Macias et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DICER- and AGO3-dependent generation of retinoic acid–induced DR2 Alu RNAs regulates human stem cell proliferation

(2012) QiDong Hu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

microRNAs associated with the different human Argonaute proteins

(2012) A. Dueck et al.   NUCLEIC ACIDS RESEARCH

The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function

(2012) Inga Loedige et al.   NUCLEIC ACIDS RESEARCH

Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing

(2012) I. Barr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes

(2012) Y. Kawahara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRBP alters human precursor microRNA processing in vitro

(2012) H. Y. Lee et al.   RNA

IRE1  Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2

(2012) J.-P. Upton et al.   SCIENCE

The Crystal Structure of Human Argonaute2

(2012) N. T. Schirle et al.   SCIENCE

MicroRNA turnover: when, how, and why

(2012) Stefan Rüegger et al.   TRENDS IN BIOCHEMICAL SCIENCES

MicroRNAs in neuronal function and dysfunction

(2012) Heh-In Im et al.   TRENDS IN NEUROSCIENCES

Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation

(2012) Hao-Ming Chang et al.   Nature Communications

Molecular Basis for Interaction of let-7 MicroRNAs with Lin28

(2011) Yunsun Nam et al.   CELL

The Exoribonuclease Nibbler Controls 3′ End Processing of MicroRNAs in Drosophila

(2011) Nan Liu et al.   CURRENT BIOLOGY

Kinetic Analysis Reveals the Fate of a MicroRNA following Target Regulation in Mammalian Cells

(2011) Alessia Baccarini et al.   CURRENT BIOLOGY

The 3′-to-5′ Exoribonuclease Nibbler Shapes the 3′ Ends of MicroRNAs Bound to Drosophila Argonaute1

(2011) Bo W. Han et al.   CURRENT BIOLOGY

Target-Mediated Protection of Endogenous MicroRNAs in C. elegans

(2011) Saibal Chatterjee et al.   DEVELOPMENTAL CELL

Hypoxia Potentiates MicroRNA-Mediated Gene Silencing through Posttranslational Modification of Argonaute2

(2011) C. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

MCPIP1 Ribonuclease Antagonizes Dicer and Terminates MicroRNA Biogenesis through Precursor MicroRNA Degradation

(2011) Hiroshi I. Suzuki et al.   MOLECULAR CELL

siRNA Repositioning for Guide Strand Selection by Human Dicer Complexes

(2011) Cameron L. Noland et al.   MOLECULAR CELL

A Primate Herpesvirus Uses the Integrator Complex to Generate Viral MicroRNAs

(2011) Demián Cazalla et al.   MOLECULAR CELL

Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm

(2011) Anthony K.L. Leung et al.   MOLECULAR CELL

Alternative miRNA Biogenesis Pathways and the Interpretation of Core miRNA Pathway Mutants

(2011) Jr-Shiuan Yang et al.   MOLECULAR CELL

Dicer recognizes the 5′ end of RNA for efficient and accurate processing

(2011) Jong-Eun Park et al.   NATURE

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

(2011) Hiroki Kaneko et al.   NATURE

Evolution of microRNA diversity and regulation in animals

(2011) Eugene Berezikov   NATURE REVIEWS GENETICS

Gene silencing by microRNAs: contributions of translational repression and mRNA decay

(2011) Eric Huntzinger et al.   NATURE REVIEWS GENETICS

PIWI-interacting small RNAs: the vanguard of genome defence

(2011) Mikiko C. Siomi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recognition of the pre-miRNA structure by Drosophila Dicer-1

(2011) Akihisa Tsutsumi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of C3PO and mechanism of human RISC activation

(2011) Xuecheng Ye et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28

(2011) Fionna E Loughlin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evolution and Functional Diversification ofMIRNAGenes

(2011) Josh T. Cuperus et al.   PLANT CELL

Glycogen Synthase Kinase 3 Beta (GSK3β) Phosphorylates the RNAase III Enzyme Drosha at S300 and S302

(2011) Xiaoli Tang et al.   PLoS One

Expanding the role of Drosha to the regulation of viral gene expression

(2011) Y.-T. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Murine cytomegalovirus encodes a miR-27 inhibitor disguised as a target

(2011) V. Libri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dicer is dispensable for asymmetric RISC loading in mammals

(2011) J. G. Betancur et al.   RNA

Vive la différence: biogenesis and evolution of microRNAs in plants and animals

(2011) Michael J Axtell et al.   GENOME BIOLOGY

Recognition of siRNA Asymmetry by TAR RNA Binding Protein

(2010) Joseph A. Gredell et al.   BIOCHEMISTRY

A Genetic Defect in Exportin-5 Traps Precursor MicroRNAs in the Nucleus of Cancer Cells

(2010) Sonia A. Melo et al.   CANCER CELL

Characterizing Light-Regulated Retinal MicroRNAs Reveals Rapid Turnover as a Common Property of Neuronal MicroRNAs

(2010) Jacek Krol et al.   CELL

Mammalian microRNAs: experimental evaluation of novel and previously annotated genes

(2010) H. R. Chiang et al.   GENES & DEVELOPMENT

Canonical and alternate functions of the microRNA biogenesis machinery

(2010) M. M. W. Chong et al.   GENES & DEVELOPMENT

Substrate-Specific Kinetics of Dicer-Catalyzed RNA Processing

(2010) Srinivas Chakravarthy et al.   JOURNAL OF MOLECULAR BIOLOGY

HSP90 Protein Stabilizes Unloaded Argonaute Complexes and Microscopic P-bodies in Human Cells

(2010) Michael Johnston et al.   MOLECULAR BIOLOGY OF THE CELL

Diverse Endonucleolytic Cleavage Sites in the Mammalian Transcriptome Depend upon MicroRNAs, Drosha, and Additional Nucleases

(2010) Fedor V. Karginov et al.   MOLECULAR CELL

Posttranscriptional Regulation of MicroRNA Biogenesis in Animals

(2010) Haruhiko Siomi et al.   MOLECULAR CELL

MicroRNA Biogenesis via Splicing and Exosome-Mediated Trimming in Drosophila

(2010) Alex S. Flynt et al.   MOLECULAR CELL

Hsc70/Hsp90 Chaperone Machinery Mediates ATP-Dependent RISC Loading of Small RNA Duplexes

(2010) Shintaro Iwasaki et al.   MOLECULAR CELL

A Mammalian Herpesvirus Uses Noncanonical Expression and Processing Mechanisms to Generate Viral MicroRNAs

(2010) Hal P. Bogerd et al.   MOLECULAR CELL

Smad Proteins Bind a Conserved RNA Sequence to Promote MicroRNA Maturation by Drosha

(2010) Brandi N. Davis et al.   MOLECULAR CELL

Structural basis for 5′-nucleotide base-specific recognition of guide RNA by human AGO2

(2010) Filipp Frank et al.   NATURE

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

(2010) Sihem Cheloufi et al.   NATURE

Phosphorylation of human Argonaute proteins affects small RNA binding

(2010) Sabine Rüdel et al.   NUCLEIC ACIDS RESEARCH

Phosphorylation of the RNase III enzyme Drosha at Serine300 or Serine302 is required for its nuclear localization

(2010) Xiaoli Tang et al.   NUCLEIC ACIDS RESEARCH

Human polynucleotide phosphorylase selectively and preferentially degrades microRNA-221 in human melanoma cells

(2010) S. K. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis

(2010) J.-S. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms that funnel RNA precursors into endogenous small-interfering RNA and microRNA biogenesis pathways in Drosophila

(2010) K. Miyoshi et al.   RNA

Structure and activity of putative intronic miRNA promoters

(2010) A. M. Monteys et al.   RNA

DGCR8 recognizes primary transcripts of microRNAs through highly cooperative binding and formation of higher-order structures

(2010) M. Faller et al.   RNA

Down-Regulation of a Host MicroRNA by a Herpesvirus saimiri Noncoding RNA

(2010) D. Cazalla et al.   SCIENCE

Target RNA-Directed Trimming and Tailing of Small Silencing RNAs

(2010) S. L. Ameres et al.   SCIENCE

A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity

(2010) D. Cifuentes et al.   SCIENCE

Making RISC

(2010) Tomoko Kawamata et al.   TRENDS IN BIOCHEMICAL SCIENCES

Sequence features associated with microRNA strand selection in humans and flies

(2009) Hai Hu et al.   BMC GENOMICS

A Functional Genetic Variant in microRNA-196a2 Is Associated with Increased Susceptibility of Lung Cancer in Chinese

(2009) T. Tian et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Posttranscriptional Crossregulation between Drosha and DGCR8

(2009) Jinju Han et al.   CELL

Phosphorylation of the Human MicroRNA-Generating Complex Mediates MAPK/Erk Signaling

(2009) Zain Paroo et al.   CELL

Origin, Biogenesis, and Activity of Plant MicroRNAs

(2009) Olivier Voinnet   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

TUT4 in Concert with Lin28 Suppresses MicroRNA Biogenesis through Pre-MicroRNA Uridylation

(2009) Inha Heo et al.   CELL

The deep evolution of metazoan microRNAs

(2009) Benjamin M. Wheeler et al.   EVOLUTION & DEVELOPMENT

Essential and overlapping functions for mammalian Argonautes in microRNA silencing

(2009) H. Su et al.   GENES & DEVELOPMENT

Dicer1 functions as a haploinsufficient tumor suppressor

(2009) M. S. Kumar et al.   GENES & DEVELOPMENT

Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2

(2009) T. Katoh et al.   GENES & DEVELOPMENT

Functional Association of the Microprocessor Complex with the Spliceosome

(2009) N. Kataoka et al.   MOLECULAR AND CELLULAR BIOLOGY

Distinct Mechanisms for MicroRNA Strand Selection by Drosophila Argonautes

(2009) Katsutomo Okamura et al.   MOLECULAR CELL

Hierarchical Rules for Argonaute Loading in Drosophila

(2009) Benjamin Czech et al.   MOLECULAR CELL

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

Active turnover modulates mature microRNA activity in Caenorhabditis elegans

(2009) Saibal Chatterjee et al.   NATURE

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

(2009) Michele Trabucchi et al.   NATURE

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes

(2009) Yanli Wang et al.   NATURE

The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2

(2009) Agnieszka Rybak et al.   NATURE CELL BIOLOGY

A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

(2009) Sonia A Melo et al.   NATURE GENETICS

Small silencing RNAs: an expanding universe

(2009) Megha Ghildiyal et al.   NATURE REVIEWS GENETICS

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ATP-dependent human RISC assembly pathways

(2009) Mayuko Yoda et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural determinants of miRNAs for RISC loading and slicer-independent unwinding

(2009) Tomoko Kawamata et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells

(2009) John P Hagan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural insights into RNA processing by the human RISC-loading complex

(2009) Hong-Wei Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genomic Analysis Suggests that mRNA Destabilization by the Microprocessor Is Specialized for the Auto-Regulation of Dgcr8

(2009) Archana Shenoy et al.   PLoS One

Alternative Processing of Primary microRNA Transcripts by Drosha Generates 5′ End Variation of Mature microRNA

(2009) Haoquan Wu et al.   PLoS One

Polymorphic mature microRNAs from passenger strand of pre-miR-146a contribute to thyroid cancer

(2009) K. Jazdzewski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide identification of targets of the drosha-pasha/DGCR8 complex

(2009) S. Kadener et al.   RNA

Post-transcriptional control of DGCR8 expression by the Microprocessor

(2009) R. Triboulet et al.   RNA

Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway

(2009) M. Ghildiyal et al.   RNA

A High-Resolution Structure of the Pre-microRNA Nuclear Export Machinery

(2009) C. Okada et al.   SCIENCE

C3PO, an Endoribonuclease That Promotes RNAi by Facilitating RISC Activation

(2009) Y. Liu et al.   SCIENCE

Structure of the Human Dicer-TRBP Complex by Electron Microscopy

(2009) Pick-Wei Lau et al.   STRUCTURE

Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies

(2008) Yan Zeng et al.   BIOCHEMICAL JOURNAL

let-7 regulates Dicer expression and constitutes a negative feedback loop

(2008) Shogo Tokumaru et al.   CARCINOGENESIS

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL

Chromatin structure analyses identify miRNA promoters

(2008) F. Ozsolak et al.   GENES & DEVELOPMENT

Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs

(2008) J. E. Babiarz et al.   GENES & DEVELOPMENT

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Primary microRNA transcript retention at sites of transcription leads to enhanced microRNA production

(2008) Jan M. Pawlicki et al.   JOURNAL OF CELL BIOLOGY

Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA

(2008) Inha Heo et al.   MOLECULAR CELL

A Human snoRNA with MicroRNA-Like Functions

(2008) Christine Ender et al.   MOLECULAR CELL

Posttranscriptional Regulation of miRNAs Harboring Conserved Terminal Loops

(2008) Gracjan Michlewski et al.   MOLECULAR CELL

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

(2008) Yanli Wang et al.   NATURE

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

Prolyl 4-hydroxylation regulates Argonaute 2 stability

(2008) Hank H. Qi et al.   NATURE

Structure of the guide-strand-containing argonaute silencing complex

(2008) Yanli Wang et al.   NATURE

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

(2008) Agnieszka Rybak et al.   NATURE CELL BIOLOGY

Primary microRNA transcripts are processed co-transcriptionally

(2008) Mariangela Morlando et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing

(2008) A. Azuma-Mukai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence

(2008) J. J. Forman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro reconstitution of the human RISC-loading complex

(2008) I. J. MacRae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma

(2008) K. Jazdzewski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two molecular features contribute to the Argonaute specificity for the microRNA and RNAi pathways in C. elegans

(2008) G. Jannot et al.   RNA

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

(2008) M. A. Newman et al.   RNA

Selective Blockade of MicroRNA Processing by Lin28

(2008) S. R. Viswanathan et al.   SCIENCE

Degradation of microRNAs by a Family of Exoribonucleases in Arabidopsis

(2008) Vanitharani Ramachandran et al.   SCIENCE

The let-7 family of microRNAs

(2008) Sarah Roush et al.   TRENDS IN CELL BIOLOGY