Regulation rewiring analysis reveals mutual regulation between STAT1 and miR-155-5p in tumor immunosurveillance in seven major cancers

Proteasome inhibitor carfilzomib interacts synergistically with histone deacetylase inhibitor vorinostat in Jurkat T-leukemia cells

(2014) Minjie Gao et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

IFN-γ Directly Controls IL-33 Protein Level through a STAT1- and LMP2-dependent Mechanism

(2014) Pavel Kopach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-155 induction in microglial cells suppresses Japanese encephalitis virus replication and negatively modulates innate immune responses

(2014) Siddhika Pareek et al.   Journal of Neuroinflammation

Reproducible combinatorial regulatory networks elucidate novel oncogenic microRNAs in non-small cell lung cancer

(2014) Ramkrishna Mitra et al.   RNA

Synergistic effects of proteasome inhibitor carfilzomib in combination with tyrosine kinase inhibitors in imatinib-sensitive and -resistant chronic myeloid leukemia models

(2014) L J Crawford et al.   Oncogenesis

miRCancer: a microRNA-cancer association database constructed by text mining on literature

(2013) B. Xie et al.   BIOINFORMATICS

MiR-19b/20a/92a regulates the self-renewal and proliferation of gastric cancer stem cells

(2013) Q. Wu et al.   JOURNAL OF CELL SCIENCE

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

The microRNA miR-155 controls CD8+ T cell responses by regulating interferon signaling

(2013) Donald T Gracias et al.   NATURE IMMUNOLOGY

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

(2013) Jun-Hao Li et al.   NUCLEIC ACIDS RESEARCH

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

The Role of Structural Disorder in the Rewiring of Protein Interactions through Evolution

(2012) Roberto Mosca et al.   MOLECULAR & CELLULAR PROTEOMICS

Database resources of the National Center for Biotechnology Information

(2012)   NUCLEIC ACIDS RESEARCH

Network rewiring is an important mechanism of gene essentiality change

(2012) Jinho Kim et al.   Scientific Reports

Gene regulatory network inference: evaluation and application to ovarian cancer allows the prioritization of drug targets

(2012) Piyush B Madhamshettiwar et al.   Genome Medicine

Uncovering MicroRNA and Transcription Factor Mediated Regulatory Networks in Glioblastoma

(2012) Jingchun Sun et al.   PLoS Computational Biology

Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference

(2012) Feixiong Cheng et al.   PLoS Computational Biology

Large-scale learning of combinatorial transcriptional dynamics from gene expression

(2011) H. M. Shahzad Asif et al.   BIOINFORMATICS

Integrative network analysis reveals active microRNAs and their functions in gastric cancer

(2011) Chien-Wei Tseng et al.   BMC Systems Biology

Thalidomide modulates Mycobacterium leprae-induced NF-κB pathway and lower cytokine response

(2011) Maristela de Oliveira Hernandez et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

TarBase 6.0: capturing the exponential growth of miRNA targets with experimental support

(2011) T. Vergoulis et al.   NUCLEIC ACIDS RESEARCH

Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery

(2011) F. Zhu et al.   NUCLEIC ACIDS RESEARCH

Inflammatory cytokines regulate microRNA-155 expression in human retinal pigment epithelial cells by activating JAK/STAT pathway

(2010) R. Krishnan Kutty et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dynamic functional modules in co-expressed protein interaction networks of dilated cardiomyopathy

(2010) Chen-Ching Lin et al.   BMC Systems Biology

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

MicroRNA control of signal transduction

(2010) Masafumi Inui et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs

(2010) C. Knox et al.   NUCLEIC ACIDS RESEARCH

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

From ‘differential expression’ to ‘differential networking’ – identification of dysfunctional regulatory networks in diseases

(2010) Alberto de la Fuente   TRENDS IN GENETICS

MicroRNAs in Cancer

(2009) Ramiro Garzon et al.   Annual Review of Medicine

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

TransmiR: a transcription factor–microRNA regulation database

(2009) Juan Wang et al.   NUCLEIC ACIDS RESEARCH

Synergy between Proteasome Inhibitors and Imatinib Mesylate in Chronic Myeloid Leukemia

(2009) Zheng Hu et al.   PLoS One

The value of proteasome inhibition in cancer

(2008) Boris Cvek et al.   DRUG DISCOVERY TODAY

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE