Polycomb-mediated loss of microRNA let-7c determines inflammatory macrophage polarization via PAK1-dependent NF-κB pathway

Chromatin Contributions to the Regulation of Innate Immunity

(2014) Stephen T. Smale et al.   Annual Review of Immunology

Interleukin-4- and Interleukin-13-Mediated Alternatively Activated Macrophages: Roles in Homeostasis and Disease

(2013) Steven J. Van Dyken et al.   Annual Review of Immunology

LIN28B-mediated expression of fetal hemoglobin and production of fetal-like erythrocytes from adult human erythroblasts ex vivo

(2013) Y. T. Lee et al.   BLOOD

Sorafenib suppresses growth and survival of hepatoma cells by accelerating degradation of enhancer of zeste homolog 2

(2013) Shanshan Wang et al.   CANCER SCIENCE

The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1- and microRNA-155 –Dependent Pathway During Atherosclerosis

(2013) Yuanyuan Wei et al.   CIRCULATION

N-acetylglucosaminyltransferase V confers hepatoma cells with resistance to anoikis through EGFR/PAK1 activation

(2013) J. Liu et al.   GLYCOBIOLOGY

DNA-dependent Activator of Interferon-regulatory Factors (DAI) Promotes Lupus Nephritis by Activating the Calcium Pathway

(2013) Weijuan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

KIT oncogene inhibition drives intratumoral macrophage M2 polarization

(2013) Michael J. Cavnar et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNA let-7c Regulates Macrophage Polarization

(2013) S. Banerjee et al.   JOURNAL OF IMMUNOLOGY

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

MicroRNA-mediated control of macrophages and its implications for cancer

(2013) Mario Leonardo Squadrito et al.   TRENDS IN IMMUNOLOGY

TAp73 is required for macrophage-mediated innate immunity and the resolution of inflammatory responses

(2012) R Tomasini et al.   CELL DEATH AND DIFFERENTIATION

Hepatitis B Virus X Protein Confers Resistance of Hepatoma Cells to Anoikis by Up-regulating and Activating p21-Activated Kinase 1

(2012) Jiejie Xu et al.   GASTROENTEROLOGY

Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis

(2012) Sandy Leung-Kuen Au et al.   HEPATOLOGY

RETRACTED: Suppressors of Cytokine Signaling 2 and 3 Diametrically Control Macrophage Polarization

(2012) Shaun Spence et al.   IMMUNITY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Cancer immunoediting by the innate immune system in the absence of adaptive immunity

(2012) Timothy O’Sullivan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Notch–RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization

(2012) Haixia Xu et al.   NATURE IMMUNOLOGY

Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization

(2012) A. Arranz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

JNK Expression by Macrophages Promotes Obesity-Induced Insulin Resistance and Inflammation

(2012) M. S. Han et al.   SCIENCE

Epigenetic regulation of macrophage polarization and function

(2012) Lionel B. Ivashkiv   TRENDS IN IMMUNOLOGY

Hepatitis B Virus Large Surface Antigen Promotes Liver Carcinogenesis by Activating the Src/PI3K/Akt Pathway

(2011) H. Liu et al.   CANCER RESEARCH

Pak1 as a Novel Therapeutic Target for Antihypertrophic Treatment in the Heart

(2011) Wei Liu et al.   CIRCULATION

Inflammatory signaling in macrophages: Transitions from acute to tolerant and alternative activation states

(2011) Lionel B. Ivashkiv   EUROPEAN JOURNAL OF IMMUNOLOGY

MicroRNAs and the resolution phase of inflammation in macrophages

(2011) Muhammad M. Alam et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Epigenetic control of macrophage polarization

(2011) Osamu Takeuch et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation

(2011) S. E. Mullican et al.   GENES & DEVELOPMENT

Leukotriene B4 amplifies NF-κB activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression

(2011) Carlos H. Serezani et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage Differentiation and Polarization via Phosphatidylinositol 3-Kinase/Akt-ERK Signaling Pathway Conferred by Serum Amyloid P Component

(2011) W. Zhang et al.   JOURNAL OF IMMUNOLOGY

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

Selective Transcription in Response to an Inflammatory Stimulus

(2010) Stephen T. Smale   CELL

Hepatitis B virus X protein blunts senescence-like growth arrest of human hepatocellular carcinoma by reducing Notch1 cleavage

(2010) Jiejie Xu et al.   HEPATOLOGY

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Blockade of Notch1 Signaling Alleviates Murine Lupus via Blunting Macrophage Activation and M2b Polarization

(2010) W. Zhang et al.   JOURNAL OF IMMUNOLOGY

Tools and landscapes of epigenetics

(2010) Alexander Tarakhovsky   NATURE IMMUNOLOGY

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

(2010) Takashi Satoh et al.   NATURE IMMUNOLOGY

An emerging role for p21-activated kinases (Paks) in viral infections

(2010) Celine Van den Broeke et al.   TRENDS IN CELL BIOLOGY

p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics

(2009) J. D. Allen et al.   BLOOD

Group I p21-activated kinases: Emerging roles in immune function and viral pathogenesis

(2009) Almudena Pacheco et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

PAK signaling in oncogenesis

(2009) P R Molli et al.   ONCOGENE

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics

(2008) S. D. Smith et al.   JOURNAL OF CELL SCIENCE

An antiinflammatory role for IKKβ through the inhibition of “classical” macrophage activation

(2008) Carol Ho Yan Fong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Small non-coding RNAs in animal development

(2008) Giovanni Stefani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Suppression of non-small cell lung tumor development by the let-7 microRNA family

(2008) M. S. Kumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

(2008) S. Varambally et al.   SCIENCE