Astrocyte and Oligodendrocyte Cross-Talk in the Central Nervous System

Dynamics of oligodendrocyte generation in multiple sclerosis

(2019) Maggie S. Y. Yeung et al.   NATURE

Aberrant oligodendroglial–vascular interactions disrupt the blood–brain barrier, triggering CNS inflammation

(2019) Jianqin Niu et al.   NATURE NEUROSCIENCE

Glutamate Transport and Preterm Brain Injury

(2019) Silvia Pregnolato et al.   Frontiers in Physiology

Ischemic stroke in neonatal and adult astrocytes

(2019) Miren Revuelta et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Multiphasic disseminated encephalomyelitis associated with herpes virus infection in a patient with TLR3 deficiency

(2019) Bruno Kusznir Vitturi et al.   Multiple Sclerosis and Related Disorders

Oligodendrocytes upregulate blood-brain barrier function through mechanisms other than the PDGF-BB/PDGFRα pathway in the barrier-tightening effect of oligodendrocyte progenitor cells

(2019) Ikuya Kimura et al.   NEUROSCIENCE LETTERS

Alexander disease: an astrocytopathy that produces a leukodystrophy

(2018) Alexander Sosunov et al.   BRAIN PATHOLOGY

Vanishing white matter: a leukodystrophy due to astrocytic dysfunction

(2018) Marianna Bugiani et al.   BRAIN PATHOLOGY

Severe White Matter Astrocytopathy in CADASIL

(2018) Yoshiki Hase et al.   BRAIN PATHOLOGY

NF‐κB activation in astrocytes drives a stage‐specific beneficial neuroimmunological response in ALS

(2018) Najwa Ouali Alami et al.   EMBO JOURNAL

MMP7 cleaves remyelination-impairing fibronectin aggregates and its expression is reduced in chronic multiple sclerosis lesions

(2018) Peng Wang et al.   GLIA

Multiple sclerosis

(2018) Alan J Thompson et al.   LANCET

Extracellular matrix-driven congenital muscular dystrophies

(2018) Payam Mohassel et al.   MATRIX BIOLOGY

Glial Cells Shape Pathology and Repair After Spinal Cord Injury

(2018) Andrew D. Gaudet et al.   Neurotherapeutics

Multiple Sclerosis

(2018) Daniel S. Reich et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic leukodystrophy

(2018) Giacomo Frati et al.   Cell Death & Disease

Selective Modulation of TNF–TNFRs Signaling: Insights for Multiple Sclerosis Treatment

(2018) Valentina Pegoretti et al.   Frontiers in Immunology

The Role of Astrocytes in Multiple Sclerosis

(2018) Gerald Ponath et al.   Frontiers in Immunology

The role of brain vasculature in neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   NATURE NEUROSCIENCE

Regulatory role of oligodendrocyte gap junctions in inflammatory demyelination

(2018) Christos P. Papaneophytou et al.   GLIA

Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease

(2018) Kelly Ceyzériat et al.   Acta Neuropathologica Communications

Regional oligodendrocytopathy and astrocytopathy precede myelin loss and blood-brain barrier disruption in a murine model of osmotic demyelination syndrome

(2017) Joanna Bouchat et al.   GLIA

Binswanger's disease: biomarkers in the inflammatory form of vascular cognitive impairment and dementia

(2017) Gary A. Rosenberg   JOURNAL OF NEUROCHEMISTRY

Osmotic Stress–Induced Defective Glial Proteostasis Contributes to Brain Demyelination after Hyponatremia Treatment

(2017) Fabrice Gankam-Kengne et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regenerating CNS myelin — from mechanisms to experimental medicines

(2017) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

Effect of glial cells on remyelination after spinal cord injury

(2017) Bin Liu et al.   Neural Regeneration Research

Heat shock protein expression in cerebral X-linked adrenoleukodystrophy reveals astrocyte stress prior to myelin loss

(2017) A. L. Görtz et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Detection of brain-directed autoantibodies in the serum of non-small cell lung cancer patients

(2017) Manoj Banjara et al.   PLoS One

Cell-specific and region-specific transcriptomics in the multiple sclerosis model: Focus on astrocytes

(2017) Noriko Itoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oligodendroglial myelination requires astrocyte-derived lipids

(2017) Nutabi Camargo et al.   PLOS BIOLOGY

Involvement of Astrocytes in Alzheimer’s Disease from a Neuroinflammatory and Oxidative Stress Perspective

(2017) Rodrigo E. González-Reyes et al.   Frontiers in Molecular Neuroscience

The ATP-Gated P2X7 Receptor As a Target for the Treatment of Drug-Resistant Epilepsy

(2017) Edward Beamer et al.   Frontiers in Neuroscience

Modulation of P2X7 Receptor during Inflammation in Multiple Sclerosis

(2017) Susanna Amadio et al.   Frontiers in Immunology

IL-17 induces reactive astrocytes and up-regulation of vascular endothelial growth factor (VEGF) through JAK/STAT signaling

(2017) Tao You et al.   Scientific Reports

Immunoregulation at the gliovascular unit in the healthy brain: A focus on Connexin 43

(2016) Anne-Cécile Boulay et al.   BRAIN BEHAVIOR AND IMMUNITY

The immunomodulatory oligodendrocyte

(2016) Thomas Zeis et al.   BRAIN RESEARCH

The multifaceted role of astrocytes in regulating myelination

(2016) Hülya Kıray et al.   EXPERIMENTAL NEUROLOGY

Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itself

(2016) Saskia Maria Burm et al.   Journal of Neuroinflammation

Origin of oligodendrocytes in mammalian forebrains: a revised perspective

(2016) Masae Naruse et al.   Journal of Physiological Sciences

Astrocytes in multiple sclerosis

(2016) Samuel K Ludwin et al.   Multiple Sclerosis Journal

Astrocytes: Key Regulators of Neuroinflammation

(2016) Emanuela Colombo et al.   TRENDS IN IMMUNOLOGY

Astrocytes in Oligodendrocyte Lineage Development and White Matter Pathology

(2016) Jiasi Li et al.   Frontiers in Cellular Neuroscience

Human iPSC-Derived Immature Astroglia Promote Oligodendrogenesis by Increasing TIMP-1 Secretion

(2016) Peng Jiang et al.   Cell Reports

Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy

(2016) Boyan Fang et al.   JAMA Neurology

Astrocytes in multiple sclerosis

(2016) Samuel K Ludwin et al.   Multiple Sclerosis Journal

NF-κB Pathways in the Pathogenesis of Multiple Sclerosis and the Therapeutic Implications

(2016) Saskia M. Leibowitz et al.   Frontiers in Molecular Neuroscience

Progressive multifocal leukoencephalopathy and immune reconstitution inflammatory syndrome (IRIS)

(2015) Jan Bauer et al.   ACTA NEUROPATHOLOGICA

Pathological differences between white and grey matter multiple sclerosis lesions

(2015) Marloes Prins et al.   Annals of the New York Academy of Sciences

Astrocytes and mitochondria from adrenoleukodystrophy protein (ABCD1)-deficient mice reveal that the adrenoleukodystrophy-associated very long-chain fatty acids target several cellular energy-dependent functions

(2015) Nicol Kruska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Glia in mammalian development and disease

(2015) J. Bradley Zuchero et al.   DEVELOPMENT

Disease-modifying treatments for multiple sclerosis - a review of approved medications

(2015) Ø. Torkildsen et al.   EUROPEAN JOURNAL OF NEUROLOGY

Demyelination Causes Adult CNS Progenitors to Revert to an Immature State and Express Immune Cues That Support Their Migration

(2015) S. Moyon et al.   JOURNAL OF NEUROSCIENCE

Immune Quiescence of the Brain Is Set by Astroglial Connexin 43

(2015) A.-C. Boulay et al.   JOURNAL OF NEUROSCIENCE

Chronic Oligodendrogenesis and Remyelination after Spinal Cord Injury in Mice and Rats

(2015) Z. C. Hesp et al.   JOURNAL OF NEUROSCIENCE

Astrocytes Promote Oligodendrogenesis after White Matter Damage via Brain-Derived Neurotrophic Factor

(2015) N. Miyamoto et al.   JOURNAL OF NEUROSCIENCE

Early disruption of glial communication via connexin gap junction in multiple sclerosis, Baló's disease and neuromyelitis optica

(2015) Katsuhisa Masaki   NEUROPATHOLOGY

GM-CSF reduces expression of chondroitin sulfate proteoglycan (CSPG) core proteins in TGF-β-treated primary astrocytes

(2015) Jung-Kyoung Choi et al.   BMB Reports

Glia in the pathogenesis of neurodegenerative diseases

(2014) Alexei Verkhratsky et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mechanisms of astrocyte development and their contributions to neurodevelopmental disorders

(2014) Steven A Sloan et al.   CURRENT OPINION IN NEUROBIOLOGY

Analysis of IL-6/gp130 family receptor expression reveals that in contrast to astroglia, microglia lack the oncostatin M receptor and functional responses to oncostatin M

(2014) Meng-Ping Hsu et al.   GLIA

Glial Scar Formation Occurs in the Human Brain after Ischemic Stroke

(2014) Lijie Huang et al.   International Journal of Medical Sciences

IL-17A Induces MIP-1α Expression in Primary Astrocytes via Src/MAPK/PI3K/NF-kB Pathways: Implications for Multiple Sclerosis

(2014) Hongwei Yi et al.   Journal of Neuroimmune Pharmacology

Remyelination in multiple sclerosis: Cellular mechanisms and novel therapeutic approaches

(2014) John A. Olsen et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Iron in multiple sclerosis: roles in neurodegeneration and repair

(2014) Erin Stephenson et al.   Nature Reviews Neurology

HCMV Induces Dysregulation of Glutamate Uptake and Transporter Expression in Human Fetal Astrocytes

(2014) Li Zhang et al.   NEUROCHEMICAL RESEARCH

Secretome Analysis of Human Oligodendrocytes Derived from Neural Stem Cells

(2014) Woo Kyung Kim et al.   PLoS One

Astrocyte-Derived Proinflammatory Cytokines Induce Hypomyelination in the Periventricular White Matter in the Hypoxic Neonatal Brain

(2014) Yiyu Deng et al.   PLoS One

Human Astrocytes: Secretome Profiles of Cytokines and Chemokines

(2014) Sung S. Choi et al.   PLoS One

Oligodendrocyte Precursor Cells Support Blood-Brain Barrier Integrity via TGF-β Signaling

(2014) Ji Hae Seo et al.   PLoS One

Early and widespread injury of astrocytes in the absence of demyelination in acute haemorrhagic leukoencephalitis

(2014) Christopher A Robinson et al.   Acta Neuropathologica Communications

Astrocyte-specific activation of TNFR2 promotes oligodendrocyte maturation by secretion of leukemia inhibitory factor

(2013) Roman Fischer et al.   GLIA

Oligodendrocyte-microglia cross-talk in the central nervous system

(2013) Laura Peferoen et al.   IMMUNOLOGY

Pathophysiology of the brain extracellular matrix: a new target for remyelination

(2013) Lorraine W. Lau et al.   NATURE REVIEWS NEUROSCIENCE

White matter astrocytes in health and disease

(2013) I. Lundgaard et al.   NEUROSCIENCE

Heterogeneity of reactive astrocytes

(2013) Mark A. Anderson et al.   NEUROSCIENCE LETTERS

Astrocyte loss and astrogliosis in neuroinflammatory disorders

(2013) Stephanie Hostenbach et al.   NEUROSCIENCE LETTERS

Chemokine contribution to neuropathic pain: Respective induction of CXCL1 and CXCR2 in spinal cord astrocytes and neurons

(2013) Zhi-Jun Zhang et al.   PAIN

The effect of glia-glia interactions on oligodendrocyte precursor cell biology during development and in demyelinating diseases

(2013) Diego Clemente et al.   Frontiers in Cellular Neuroscience

Astrocytes: Emerging stars in leukodystrophy pathogenesis

(2013) Angela Lanciotti et al.   Translational Neuroscience

Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination

(2012) Lorraine W. Lau et al.   ANNALS OF NEUROLOGY

Progressive Multifocal Leukoencephalopathy: Why Gray and White Matter

(2012) Sarah Gheuens et al.   Annual Review of Pathology-Mechanisms of Disease

Astrocytes and disease: a neurodevelopmental perspective

(2012) A. V. Molofsky et al.   GENES & DEVELOPMENT

Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development

(2012) María Cristina Ortega et al.   GLIA

Astrocytic regulation of glutamate homeostasis in epilepsy

(2012) Douglas A. Coulter et al.   GLIA

Molecular Mechanisms of Oligodendrocyte Injury in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

(2012) Jilpa Patel et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A possible role for inflammation in mediating apoptosis of oligodendrocytes as induced by the Lyme disease spirochete Borrelia burgdorferi

(2012) Geeta Ramesh et al.   Journal of Neuroinflammation

Polyomavirus JC infection inhibits differentiation of oligodendrocyte progenitor cells

(2012) Armine Darbinyan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

IFN-γ Signaling to Astrocytes Protects from Autoimmune Mediated Neurological Disability

(2012) Claudia Hindinger et al.   PLoS One

Pathology of Demyelinating Diseases

(2011) Bogdan F.Gh. Popescu et al.   Annual Review of Pathology-Mechanisms of Disease

CXCL8 protects human neurons from amyloid-β-induced neurotoxicity: Relevance to Alzheimer’s disease

(2011) Ashutosh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Astrocytes in the tempest of multiple sclerosis

(2011) Djordje Miljković et al.   FEBS LETTERS

Tissue transglutaminase activity is involved in the differentiation of oligodendrocyte precursor cells into myelin-forming oligodendrocytes during CNS remyelination

(2011) Miriam E. Van Strien et al.   GLIA

Corticosteroids Impair Remyelination in the Corpus Callosum of Cuprizone-Treated Mice

(2011) T. Clarner et al.   JOURNAL OF NEUROENDOCRINOLOGY

Astrocytes Are an Early Target in Osmotic Demyelination Syndrome

(2011) F. Gankam Kengne et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Precursor Cell Biology and the Development of Astrocyte Transplantation Therapies: Lessons from Spinal Cord Injury

(2011) Mark Noble et al.   Neurotherapeutics

The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

(2011) J. I. Alvarez et al.   SCIENCE

Astrocyte–neuron metabolic relationships: for better and for worse

(2011) Igor Allaman et al.   TRENDS IN NEUROSCIENCES

In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects

(2010) M. Faideau et al.   HUMAN MOLECULAR GENETICS

CCL2 modulates cytokine production in cultured mouse astrocytes

(2010) Bridgette D Semple et al.   Journal of Neuroinflammation

How factors secreted from astrocytes impact myelin repair

(2010) Craig S. Moore et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cytokine and chemokine profiles in neuromyelitis optica: significance of interleukin-6

(2010) Akiyuki Uzawa et al.   Multiple Sclerosis Journal

Developmental genetics of vertebrate glial–cell specification

(2010) David H. Rowitch et al.   NATURE

Transgenic Inhibition of Astroglial NF- B Improves Functional Outcome in Experimental Autoimmune Encephalomyelitis by Suppressing Chronic Central Nervous System Inflammation

(2009) R. Brambilla et al.   JOURNAL OF IMMUNOLOGY

Neuropathology of Cockayne syndrome: Evidence for impaired development, premature aging, and neurodegeneration

(2009) Karen M. Weidenheim et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Cholesterol involvement in the pathogenesis of neurodegenerative diseases

(2009) Jun-Ping Liu et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The bright side of the glial scar in CNS repair

(2009) Asya Rolls et al.   NATURE REVIEWS NEUROSCIENCE

Are Astrocytes the Missing Link Between Lack of Brain Aspartoacylase Activity and the Spongiform Leukodystrophy in Canavan Disease?

(2009) Morris H. Baslow et al.   NEUROCHEMICAL RESEARCH

Astrocyte, the star avatar: redefined

(2008) Pankaj Seth et al.   JOURNAL OF BIOSCIENCES

Gap Junctions Couple Astrocytes and Oligodendrocytes

(2008) Jennifer L. Orthmann-Murphy et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The life, death, and replacement of oligodendrocytes in the adult CNS

(2008) Dana M. McTigue et al.   JOURNAL OF NEUROCHEMISTRY

Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain

(2008) J.E. Simpson et al.   NEUROBIOLOGY OF AGING

Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis

(2007) John S. Tzartos et al.   AMERICAN JOURNAL OF PATHOLOGY