Pathological differences between white and grey matter multiple sclerosis lesions

Activation Status of Human Microglia Is Dependent on Lesion Formation Stage and Remyelination in Multiple Sclerosis

(2015) Laura A.N. Peferoen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The influence ofHLA-DRB1*15on motor cortical pathology in multiple sclerosis

(2015) Richard L. Yates et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic

(2015) Sharon W. Way et al.   Nature Communications

Increased PK11195-PET binding in normal-appearing white matter in clinically isolated syndrome

(2014) Paolo Giannetti et al.   BRAIN

Swift Entry of Myelin-Specific T Lymphocytes into the Central Nervous System in Spontaneous Autoimmune Encephalomyelitis

(2014) G. C. Furtado et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Th1 Cells Facilitate the Entry of Th17 Cells to the Central Nervous System during Experimental Autoimmune Encephalomyelitis

(2014) R. A. O'Connor et al.   JOURNAL OF IMMUNOLOGY

Multiple sclerosis deep grey matter: the relation between demyelination, neurodegeneration, inflammation and iron

(2014) Lukas Haider et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Discrepancy in CCL2 and CCR2 expression in white versus grey matter hippocampal lesions of Multiple Sclerosis patients

(2014) Marloes Prins et al.   Acta Neuropathologica Communications

Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons

(2013) Shailender Singh et al.   ACTA NEUROPATHOLOGICA

Characteristics of differentiated CD8+ and CD4+ T cells present in the human brain

(2013) Joost Smolders et al.   ACTA NEUROPATHOLOGICA

Meningeal and choroid plexus cells—Novel drug targets for CNS disorders

(2013) Mike Dragunow   BRAIN RESEARCH

The Benefits and Detriments of Macrophages/Microglia in Models of Multiple Sclerosis

(2013) Khalil S. Rawji et al.   Clinical & Developmental Immunology

Microglia in normal appearing white matter of multiple sclerosis are alerted but immunosuppressed

(2013) Jeroen Melief et al.   GLIA

Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status

(2013) Daphne YS Vogel et al.   Journal of Neuroinflammation

How Do Immune Cells Support and Shape the Brain in Health, Disease, and Aging?

(2013) M. Schwartz et al.   JOURNAL OF NEUROSCIENCE

Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation

(2013) Yichuan Xiao et al.   NATURE MEDICINE

Microglia: Multiple roles in surveillance, circuit shaping, and response to injury

(2013) E. E. Benarroch   NEUROLOGY

Oxidative Stress and Proinflammatory Cytokines Contribute to Demyelination and Axonal Damage in a Cerebellar Culture Model of Neuroinflammation

(2013) Alessandra di Penta et al.   PLoS One

CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging

(2013) K. Baruch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglia: Scapegoat, Saboteur, or Something Else?

(2013) A. Aguzzi et al.   SCIENCE

Natural killer cells and their receptors in multiple sclerosis

(2012) Gurman Kaur et al.   BRAIN

Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination

(2012) Thomas Skripuletz et al.   BRAIN

Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis

(2012) Sung R. Choi et al.   BRAIN

CD200-CD200R1 interaction contributes to neuroprotective effects of anandamide on experimentally induced inflammation

(2012) Miriam Hernangómez et al.   GLIA

Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions

(2012) Tim Clarner et al.   GLIA

Inflammatory Response and Chemokine Expression in the White Matter Corpus Callosum and Gray Matter Cortex Region During Cuprizone-Induced Demyelination

(2012) J. P. Buschmann et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Improved detection of cortical MS lesions with phase-sensitive inversion recovery MRI

(2012) Varun Sethi et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Fatigue in multiple sclerosis — A brief review

(2012) Isuru Induruwa et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Microstructural magnetic resonance imaging of cortical lesions in multiple sclerosis

(2012) M Filippi et al.   Multiple Sclerosis Journal

Will the real multiple sclerosis please stand up?

(2012) Peter K. Stys et al.   NATURE REVIEWS NEUROSCIENCE

Increased PK11195 PET binding in the cortex of patients with MS correlates with disability

(2012) M. Politis et al.   NEUROLOGY

Heterogeneity of cortical lesions in multiple sclerosis: Clinical and pathologic implications

(2012) E.-J. Kooi et al.   NEUROLOGY

The evidence for a role of B cells in multiple sclerosis

(2012) G. Disanto et al.   NEUROLOGY

Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation

(2012) Dimitrios Davalos et al.   Nature Communications

Pathology of Demyelinating Diseases

(2011) Bogdan F.Gh. Popescu et al.   Annual Review of Pathology-Mechanisms of Disease

Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis

(2011) Owain W. Howell et al.   BRAIN

Age related changes in microglial phenotype vary between CNS regions: Grey versus white matter differences

(2011) Adam D. Hart et al.   BRAIN BEHAVIOR AND IMMUNITY

Astrocytes in the tempest of multiple sclerosis

(2011) Djordje Miljković et al.   FEBS LETTERS

Functional adaptive changes within the hippocampal memory system of patients with multiple sclerosis

(2011) Hanneke E. Hulst et al.   HUMAN BRAIN MAPPING

Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes

(2011) Miri Gitik et al.   Journal of Neuroinflammation

The relationship between infratentorial lesions, balance deficit and accidental falls in multiple sclerosis

(2011) Luca Prosperini et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Characterisation of microglia during de- and remyelination: Can they create a repair promoting environment?

(2011) Elke Verena Voß et al.   NEUROBIOLOGY OF DISEASE

A case of multiple sclerosis presenting with inflammatory cortical demyelination

(2011) B. F. G. Popescu et al.   NEUROLOGY

Review: The architecture of inflammatory demyelinating lesions: implications for studies on pathogenesis

(2011) H. Lassmann   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Inflammatory Cortical Demyelination in Early Multiple Sclerosis

(2011) Claudia F. Lucchinetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

(2010) Colleen M. Niswender et al.   Annual Review of Pharmacology and Toxicology

Inflammation, demyelination, and degeneration — Recent insights from MS pathology

(2010) Christine Stadelmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis

(2010) Áine C. Murphy et al.   BRAIN BEHAVIOR AND IMMUNITY

T cells in multiple sclerosis and experimental autoimmune encephalomyelitis

(2010) J. M. Fletcher et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

Clinico-pathological evidence that axonal loss underlies disability in progressive multiple sclerosis

(2010) Emma C Tallantyre et al.   Multiple Sclerosis Journal

Imaging distribution and frequency of cortical lesions in patients with multiple sclerosis

(2010) M. Calabrese et al.   NEUROLOGY

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

The histopathology of grey matter demyelination in multiple sclerosis

(2009) L. Bø   ACTA NEUROLOGICA SCANDINAVICA

Multiple sclerosis: Distribution of inflammatory cells in newly forming lesions

(2009) Andrew P. D. Henderson et al.   ANNALS OF NEUROLOGY

Physical and Cognitive Functioning After 3 Years Can Be Predicted Using Information From the Diagnostic Process in Recently Diagnosed Multiple Sclerosis

(2009) Vincent de Groot et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Sensorimotor dysfunction in multiple sclerosis and column-specific magnetization transfer-imaging abnormalities in the spinal cord

(2009) K. M. Zackowski et al.   BRAIN

Regional differences between grey and white matter in cuprizone induced demyelination

(2009) Viktoria Gudi et al.   BRAIN RESEARCH

Protective effects of microglia in multiple sclerosis

(2009) Isabella Napoli et al.   EXPERIMENTAL NEUROLOGY

The astrocytic response in early experimental autoimmune encephalomyelitis occurs across both the grey and white matter compartments

(2009) Hong Pham et al.   JOURNAL OF NEUROIMMUNOLOGY

Distribution of the Immune Inhibitory Molecules CD200 and CD200R in the Normal Central Nervous System and Multiple Sclerosis Lesions Suggests Neuron-Glia and Glia-Glia Interactions

(2009) Nathalie Koning et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

Cortical lesions in primary progressive multiple sclerosis: A 2-year longitudinal MR study

(2009) M. Calabrese et al.   NEUROLOGY

Interferon-  mechanisms of action in multiple sclerosis

(2009) S. Dhib-Jalbut et al.   NEUROLOGY

Trigeminal neuralgia and pain related to multiple sclerosis

(2009) G. Cruccu et al.   PAIN

Multiple Sclerosis: An Immune or Neurodegenerative Disorder?

(2008) Bruce D. Trapp et al.   Annual Review of Neuroscience

Shedded neuronal ICAM-5 suppresses T-cell activation

(2008) L. Tian et al.   BLOOD

Substantial Archaeocortical Atrophy and Neuronal Loss in Multiple Sclerosis

(2008) Dimitrios Papadopoulos et al.   BRAIN PATHOLOGY

Memory impairment in multiple sclerosis: correlation with deep grey matter and mesial temporal atrophy

(2008) R H B Benedict et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Regional variations in the extent and pattern of grey matter demyelination in multiple sclerosis: a comparison between the cerebral cortex, cerebellar cortex, deep grey matter nuclei and the spinal cord

(2008) C P Gilmore et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Perivascular Spaces and the Two Steps to Neuroinflammation

(2008) Trevor Owens et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cognitive impairment in multiple sclerosis

(2008) Nancy D Chiaravalloti et al.   LANCET NEUROLOGY

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Multiple sclerosis and Alzheimer's disease

(2007) Assunta Dal Bianco et al.   ANNALS OF NEUROLOGY