Mitochondrial dysfunction in age-related macular degeneration: melatonin as a potential treatment
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Title
Mitochondrial dysfunction in age-related macular degeneration: melatonin as a potential treatment
Authors
Keywords
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Journal
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume -, Issue -, Pages 1-20
Publisher
Informa UK Limited
Online
2020-03-02
DOI
10.1080/14728222.2020.1737015
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Note: Only part of the references are listed.- Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cells
- (2019) Lucas Sagrillo-Fagundes et al. PLoS One
- Molecular Aspects of Melatonin Treatment in Tinnitus; a Review
- (2019) Azam Hosseinzadeh et al. CURRENT DRUG TARGETS
- Melatonin attenuated retinal neovascularization and neuroglial dysfunction by inhibition of HIF-1α-VEGF pathway in oxygen-induced retinopathy mice
- (2018) Yue Xu et al. JOURNAL OF PINEAL RESEARCH
- Idiopathic pulmonary fibrosis (IPF) signaling pathways and protective roles of melatonin
- (2018) Azam Hosseinzadeh et al. LIFE SCIENCES
- Diabetic retinopathy pathogenesis and the ameliorating effects of melatonin; involvement of autophagy, inflammation and oxidative stress
- (2018) Ehsan Dehdashtian et al. LIFE SCIENCES
- Oxidation of Atg3 and Atg7 mediates inhibition of autophagy
- (2018) Karen Frudd et al. Nature Communications
- Loss of the Mitochondrial Fatty Acid β-Oxidation Protein Medium-Chain Acyl-Coenzyme A Dehydrogenase Disrupts Oxidative Phosphorylation Protein Complex Stability and Function
- (2018) Sze Chern Lim et al. Scientific Reports
- Intraocular inflammatory cytokines in patients with neovascular age-related macular degeneration before and after initiation of intravitreal injection of anti-VEGF inhibitor
- (2018) Tomohito Sato et al. Scientific Reports
- Melatonin Regulates Apoptosis and Autophagy Via ROS-MST1 Pathway in Subarachnoid Hemorrhage
- (2018) Ligen Shi et al. Frontiers in Molecular Neuroscience
- Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3
- (2018) Russel Reiter et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Age-Related Macular Degeneration (AMD): Alzheimer's Disease in the Eye?
- (2018) Kai Kaarniranta et al. JOURNAL OF ALZHEIMERS DISEASE
- Melatonin prevents senescence of canine adipose-derived mesenchymal stem cells through activating NRF2 and inhibiting ER stress
- (2018) Jia Fang et al. Aging-US
- Oxidative/nitrosative stress, autophagy and apoptosis as therapeutic targets of melatonin in idiopathic pulmonary fibrosis
- (2018) Azam Hosseinzadeh et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Therapeutic potential of melatonin related to its role as an autophagy regulator: A review
- (2018) Jose A. Boga et al. JOURNAL OF PINEAL RESEARCH
- Melatonin signaling affects the timing in the daily rhythm of phagocytic activity by the retinal pigment epithelium
- (2017) Virgine Laurent et al. EXPERIMENTAL EYE RESEARCH
- Human transporters, PEPT1/2, facilitate melatonin transportation into mitochondria of cancer cells: An implication of the therapeutic potential
- (2017) Xiaokui Huo et al. JOURNAL OF PINEAL RESEARCH
- Melatonin and sirtuins: A “not-so unexpected” relationship
- (2017) Juan C. Mayo et al. JOURNAL OF PINEAL RESEARCH
- The complement system in age-related macular degeneration: A review of rare genetic variants and implications for personalized treatment
- (2017) Maartje J. Geerlings et al. MOLECULAR IMMUNOLOGY
- Melatonin protects rats from radiotherapy-induced small intestine toxicity
- (2017) Beatriz Fernández-Gil et al. PLoS One
- Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release
- (2017) Yalikun Suofu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration
- (2017) Nady Golestaneh et al. Cell Death & Disease
- Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation
- (2017) Shenglong Cao et al. Scientific Reports
- SIRT3: Oncogene and Tumor Suppressor in Cancer
- (2017) Margalida Torrens-Mas et al. Cancers
- Increased choroidal mast cells and their degranulation in age-related macular degeneration
- (2016) Imran A Bhutto et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Inflammation and its role in age-related macular degeneration
- (2016) Anu Kauppinen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Increased retinal mtDNA damage in the CFH variant associated with age-related macular degeneration
- (2016) Deborah A. Ferrington et al. EXPERIMENTAL EYE RESEARCH
- Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics
- (2016) Dun-Xian Tan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Possible Involvement of the Inhibition of NF-κB Factor in Anti-Inflammatory Actions That Melatonin Exerts on Mast Cells
- (2016) M.D. Maldonado et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Apoptosis signaling pathways in osteoarthritis and possible protective role of melatonin
- (2016) Azam Hosseinzadeh et al. JOURNAL OF PINEAL RESEARCH
- Melatonin as an antioxidant: under promises but over delivers
- (2016) Russel J. Reiter et al. JOURNAL OF PINEAL RESEARCH
- On the significance of an alternate pathway of melatonin synthesis via 5-methoxytryptamine: comparisons across species
- (2016) Dun-Xian Tan et al. JOURNAL OF PINEAL RESEARCH
- Melatonin alleviates acute lung injury through inhibiting the NLRP3 inflammasome
- (2016) Yong Zhang et al. JOURNAL OF PINEAL RESEARCH
- Melatonin prevents cytosolic calcium overload, mitochondrial damage and cell death due to toxically high doses of dexamethasone-induced oxidative stress in human neuroblastoma SH-SY5Y cells
- (2016) Wilasinee Suwanjang et al. NEUROCHEMISTRY INTERNATIONAL
- Melatonin in Retinal Physiology and Pathology: The Case of Age-Related Macular Degeneration
- (2016) Janusz Blasiak et al. Oxidative Medicine and Cellular Longevity
- Glioblastoma, hypoxia and autophagy: a survival-prone ‘ménage-à-trois’
- (2016) Soha Jawhari et al. Cell Death & Disease
- HTRA1 promoter variant differentiates polypoidal choroidal vasculopathy from exudative age-related macular degeneration
- (2016) Tsz Kin Ng et al. Scientific Reports
- Deletion of autophagy inducerRB1CC1results in degeneration of the retinal pigment epithelium
- (2015) Jingyu Yao et al. Autophagy
- ATG14 controls SNARE-mediated autophagosome fusion with a lysosome
- (2015) Rong Liu et al. Autophagy
- The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance
- (2015) Changhan Lee et al. Cell Metabolism
- Molecular Mechanisms of Mitochondrial Autophagy/Mitophagy in the Heart
- (2015) T. Saito et al. CIRCULATION RESEARCH
- Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice
- (2015) José A. García et al. FASEB JOURNAL
- Investigating Mitochondria as a Target for Treating Age-Related Macular Degeneration
- (2015) M. R. Terluk et al. JOURNAL OF NEUROSCIENCE
- Melatonin: an ancient molecule that makes oxygen metabolically tolerable
- (2015) Lucien C. Manchester et al. JOURNAL OF PINEAL RESEARCH
- Melatonin as a Potent and Inducible Endogenous Antioxidant: Synthesis and Metabolism
- (2015) Dun-Xian Tan et al. MOLECULES
- Mitochondrial decline precedes phenotype development in the complement factor H mouse model of retinal degeneration but can be corrected by near infrared light
- (2015) Karin C. Calaza et al. NEUROBIOLOGY OF AGING
- Melatonin protects the brain from apoptosis by enhancement of autophagy after traumatic brain injury in mice
- (2015) Ke Ding et al. NEUROCHEMISTRY INTERNATIONAL
- Regulation of age-related macular degeneration-like pathology by complement factor H
- (2015) Christopher B. Toomey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD
- (2014) Sayak K Mitter et al. Autophagy
- Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow–Robin perivascular spaces
- (2014) Russel J. Reiter et al. Brain Structure & Function
- Receptor-mediated mitophagy in yeast and mammalian systems
- (2014) Lei Liu et al. CELL RESEARCH
- Melatonin and amfenac modulate calcium entry, apoptosis and oxidative stress in ARPE-19 cell culture exposed to blue light irradiation (405 nm)
- (2014) M Argun et al. EYE
- Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis
- (2014) Francisco Ortiz et al. JOURNAL OF PINEAL RESEARCH
- Cargo recognition and trafficking in selective autophagy
- (2014) Alexandra Stolz et al. NATURE CELL BIOLOGY
- Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
- (2014) Antonio Ayala et al. Oxidative Medicine and Cellular Longevity
- Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?
- (2013) G C Higgins et al. BRITISH JOURNAL OF PHARMACOLOGY
- Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis
- (2013) D Westphal et al. CELL DEATH AND DIFFERENTIATION
- Atorvastatin Attenuates Bleomycin-Induced Pulmonary Fibrosis via Suppressing iNOS Expression and the CTGF (CCN2)/ERK Signaling Pathway
- (2013) Bo Zhu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mitochondrial energetic metabolism-some general principles
- (2013) Jean-Pierre Mazat et al. IUBMB LIFE
- Apoptosis Regulation at the Mitochondrial Outer Membrane
- (2013) Laura A. Gillies et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Melatonin-enhanced autophagy protects against neural apoptosis via a mitochondrial pathway in early brain injury following a subarachnoid hemorrhage
- (2013) Jingyin Chen et al. JOURNAL OF PINEAL RESEARCH
- The role of iron and reactive oxygen species in cell death
- (2013) Scott J Dixon et al. Nature Chemical Biology
- Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2
- (2013) Yasuhiro Maejima et al. NATURE MEDICINE
- Seven-Year Outcomes in Ranibizumab-Treated Patients in ANCHOR, MARINA, and HORIZON
- (2013) Soraya Rofagha et al. OPHTHALMOLOGY
- JNK inhibition reduces apoptosis and neovascularization in a murine model of age-related macular degeneration
- (2013) H. Du et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- FoxO3a is activated and executes neuron death via Bim in response to β-amyloid
- (2013) P Sanphui et al. Cell Death & Disease
- Melatonin-mitochondria Interplay in Health and Disease
- (2012) Dario Acuna Castroviejo et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Melatonin and mitochondrial dysfunction in the central nervous system
- (2012) Daniel P. Cardinali et al. HORMONES AND BEHAVIOR
- Involvement of melatonin in autophagy-mediated mouse hepatoma H22 cell survival
- (2012) Chang Liu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- OXIDATIVE PHOSPHORYLATION: Kinetic and Thermodynamic Correlation between Electron Flow, Proton Translocation, Oxygen Consumption and ATP Synthesis under Close to In Vivo Concentrations of Oxygen
- (2012) Baltazar D. Reynafarje et al. International Journal of Medical Sciences
- Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light-induced damage
- (2012) Kiichiro Okano et al. JOURNAL OF NEUROCHEMISTRY
- Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity
- (2012) Jae-Kyo Jeong et al. JOURNAL OF PINEAL RESEARCH
- Melatonin regulates the calcium-buffering proteins, parvalbumin and hippocalcin, in ischemic brain injury
- (2012) Phil-Ok Koh JOURNAL OF PINEAL RESEARCH
- Melatonin induces autophagy via an mTOR-dependent pathway and enhances clearance of mutant-TGFBIp
- (2012) Seung-Il Choi et al. JOURNAL OF PINEAL RESEARCH
- Biology of the Heat Shock Response and Protein Chaperones: Budding Yeast (Saccharomyces cerevisiae) as a Model System
- (2012) J. Verghese et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Role of melatonin in the regulation of autophagy and mitophagy: A review
- (2012) Ana Coto-Montes et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Understanding age-related macular degeneration (AMD): Relationships between the photoreceptor/retinal pigment epithelium/Bruch’s membrane/choriocapillaris complex
- (2012) Imran Bhutto et al. MOLECULAR ASPECTS OF MEDICINE
- HORIZON: An Open-Label Extension Trial of Ranibizumab for Choroidal Neovascularization Secondary to Age-Related Macular Degeneration
- (2012) Michael A. Singer et al. OPHTHALMOLOGY
- Mitochondrial Fission, Fusion, and Stress
- (2012) R. J. Youle et al. SCIENCE
- Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration
- (2011) Kati Kinnunen et al. ACTA OPHTHALMOLOGICA
- Mechanisms of mitochondria and autophagy crosstalk
- (2011) Angelika S. Rambold et al. CELL CYCLE
- Molecular chaperones in targeting misfolded proteins for ubiquitin-dependent degradation
- (2011) Franziska Kriegenburg et al. FEBS Journal
- Anti-apoptotic effects of melatonin in retinal pigment epithelial cells
- (2011) Yang Fu Frontiers in Bioscience-Landmark
- HtrA1 sensitizes ovarian cancer cells to cisplatin-induced cytotoxicity by targeting XIAP for degradation
- (2011) Xiaoping He et al. INTERNATIONAL JOURNAL OF CANCER
- Nickel exposure induces oxidative damage to mitochondrial DNA in Neuro2a cells: the neuroprotective roles of melatonin
- (2011) Shang-Cheng Xu et al. JOURNAL OF PINEAL RESEARCH
- Functional evidence for nitric oxide production by skeletal-muscle mitochondria from lipopolysaccharide-treated mice
- (2011) Enara Aguirre et al. MITOCHONDRION
- Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks
- (2011) S. Alers et al. MOLECULAR AND CELLULAR BIOLOGY
- Complement factor H binds malondialdehyde epitopes and protects from oxidative stress
- (2011) David Weismann et al. NATURE
- 5′-Adenosine Monophosphate-Activated Protein Kinase–Mammalian Target of Rapamycin Axis As Therapeutic Target for Age-Related Macular Degeneration
- (2011) Juha M.T. Hyttinen et al. REJUVENATION RESEARCH
- Mitochondrial regulation of cell death: Processing of apoptosis-inducing factor (AIF)
- (2010) Erik Norberg et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The role of anti-inflammatory agents in age-related macular degeneration (AMD) treatment
- (2010) Y Wang et al. EYE
- Autophagy: cellular and molecular mechanisms
- (2010) Danielle Glick et al. JOURNAL OF PATHOLOGY
- The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-α toxicity involves membrane melatonin receptors
- (2010) Arabinda Das et al. JOURNAL OF PINEAL RESEARCH
- The Importance of Mitochondria in Age-Related and Inherited Eye Disorders
- (2010) Stuart G. Jarrett et al. OPHTHALMIC RESEARCH
- Free Radicals, Antioxidants and Eye Diseases: Evidence from Epidemiological Studies on Cataract and Age-Related Macular Degeneration
- (2010) A.E. Fletcher OPHTHALMIC RESEARCH
- ARMS2 (LOC387715) Variants in Japanese Patients with Exudative Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy
- (2009) Norimoto Gotoh et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Regulation Mechanisms and Signaling Pathways of Autophagy
- (2009) Congcong He et al. Annual Review of Genetics
- Long-term melatonin administration protects brain mitochondria from aging
- (2009) Miguel Carretero et al. JOURNAL OF PINEAL RESEARCH
- Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines
- (2009) Rüdiger Hardeland et al. JOURNAL OF PINEAL RESEARCH
- Caspase-independent Mitochondrial Cell Death Results from Loss of Respiration, Not Cytotoxic Protein Release
- (2009) Lydia Lartigue et al. MOLECULAR BIOLOGY OF THE CELL
- Mitochondrial DNA Variants of Respiratory Complex I that Uniquely Characterize Haplogroup T2 Are Associated with Increased Risk of Age-Related Macular Degeneration
- (2009) John Paul SanGiovanni et al. PLoS One
- MAP kinase pathways in UV-induced apoptosis of retinal pigment epithelium ARPE19 cells
- (2008) Raphaël Roduit et al. APOPTOSIS
- Thirty years of protein translocation into mitochondria: Unexpectedly complex and still puzzling
- (2008) Dejana Mokranjac et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells
- (2008) Tuomas Ryhänen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Metabolism of melatonin by cytochrome P450s in rat liver mitochondria and microsomes
- (2008) Igor Semak et al. JOURNAL OF PINEAL RESEARCH
- Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production
- (2008) Ana López et al. JOURNAL OF PINEAL RESEARCH
- Age-related macular degeneration
- (2008) Hanna R Coleman et al. LANCET
- Age-Related Macular Degeneration
- (2008) Rama D. Jager et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mitochondrial DNA Polymorphism A4917G Is Independently Associated with Age-Related Macular Degeneration
- (2008) Jeffrey A. Canter et al. PLoS One
- Chronic Cigarette Smoke Causes Oxidative Damage and Apoptosis to Retinal Pigmented Epithelial Cells in Mice
- (2008) Masashi Fujihara et al. PLoS One
- Mitochondrial DNA damage and its potential role in retinal degeneration
- (2008) S JARRETT et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Regulation of retinal blood flow in health and disease
- (2008) Constantin J. Pournaras et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Molecular pathology of age-related macular degeneration
- (2008) Xiaoyan Ding et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Further mapping of 10q26 supports strong association of HTRA1 polymorphisms with age-related macular degeneration
- (2008) Daniel Gibbs et al. VISION RESEARCH
- Carotenoid derived aldehydes-induced oxidative stress causes apoptotic cell death in human retinal pigment epithelial cells
- (2007) Nilesh M. Kalariya et al. EXPERIMENTAL EYE RESEARCH
- Melatonin antagonizes the intrinsic pathway of apoptosis via mitochondrial targeting of Bcl-2
- (2007) Flavia Radogna et al. JOURNAL OF PINEAL RESEARCH
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