Melatonin protects rats from radiotherapy-induced small intestine toxicity

Melatonin decreases the expression of inflammation and apoptosis markers in the lung of a senescence-accelerated mice model

(2016) Ángela Puig et al.   EXPERIMENTAL GERONTOLOGY

Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin

(2016) Huayqui Volt et al.   JOURNAL OF PINEAL RESEARCH

Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network

(2016) María E. Díaz-Casado et al.   JOURNAL OF PINEAL RESEARCH

Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network

(2016) Carolina Doerrier et al.   MITOCHONDRION

Mucositis

(2015) Alessandro Villa et al.   CURRENT OPINION IN ONCOLOGY

Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice

(2015) José A. García et al.   FASEB JOURNAL

Melatonin as a treatment for gastrointestinal cancer: a review

(2015) Zhenlong Xin et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as a Potent and Inducible Endogenous Antioxidant: Synthesis and Metabolism

(2015) Dun-Xian Tan et al.   MOLECULES

Inflammasome Activation Is Reactive Oxygen Species Dependent and Mediates Irinotecan-Induced Mucositis through IL-1β and IL-18 in Mice

(2014) Raquel D.N. Arifa et al.   AMERICAN JOURNAL OF PATHOLOGY

Extrapineal melatonin: sources, regulation, and potential functions

(2014) Darío Acuña-Castroviejo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Melatonin treatment induces interplay of apoptosis, autophagy, and senescence in human colorectal cancer cells

(2014) Yunkyung Hong et al.   JOURNAL OF PINEAL RESEARCH

Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis

(2014) Francisco Ortiz et al.   JOURNAL OF PINEAL RESEARCH

Alleviating mucositis: are we on track for a novel therapeutic?

(2014) Rajesh V Lalla   Expert Review of Gastroenterology & Hepatology

Protective effect of genistein on radiation-induced intestinal injury in tumor bearing mice

(2013) Tae Gen Son et al.   BMC Complementary and Alternative Medicine

Irradiation Induced Injury Reduces Energy Metabolism in Small Intestine of Tibet Minipigs

(2013) Yu-Jue Wang et al.   PLoS One

Emerging evidence on the pathobiology of mucositis

(2013) Noor Al-Dasooqi et al.   SUPPORTIVE CARE IN CANCER

Analysis of the daily changes of melatonin receptors in the rat liver

(2012) Carmen Venegas et al.   JOURNAL OF PINEAL RESEARCH

Radiation-induced damage in different segments of the rat intestine after external beam irradiation of the liver

(2011) Silke Cameron et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations

(2011) Carmen Venegas et al.   JOURNAL OF PINEAL RESEARCH

Serum levels of NF-κB and pro-inflammatory cytokines following administration of mucotoxic drugs

(2010) Richard M Logan et al.   CANCER BIOLOGY & THERAPY

Irinotecan Injures Tight Junction and Causes Bacterial Translocation in Rat

(2010) Toshihiro Nakao et al.   JOURNAL OF SURGICAL RESEARCH

Pro-inflammatory cytokines play a key role in the development of radiotherapy-induced gastrointestinal mucositis

(2010) Zhi Ong et al.   Radiation Oncology

Efficacy of Superoxide Dismutase Mimetic M40403 in Attenuating Radiation-Induced Oral Mucositis in Hamsters

(2008) C. K. Murphy et al.   CLINICAL CANCER RESEARCH

What Causes the Radiation Gastrointestinal Syndrome?: Overview

(2008) Martin Brown   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA