Atorvastatin Attenuates Bleomycin-Induced Pulmonary Fibrosis via Suppressing iNOS Expression and the CTGF (CCN2)/ERK Signaling Pathway

Acute exacerbations in patients with idiopathic pulmonary fibrosis

(2013) Dong Kim   RESPIRATORY RESEARCH

Endostatin, an angiogenesis inhibitor, ameliorates bleomycin-induced pulmonary fibrosis in rats

(2013) Yun-Yan Wan et al.   RESPIRATORY RESEARCH

Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: A biphasic experimental study

(2013) Palanivel Chitra et al.   TOXICOLOGY LETTERS

Evidence-based Use of Statins for Primary Prevention of Cardiovascular Disease

(2012) C. Michael Minder et al.   AMERICAN JOURNAL OF MEDICINE

Oxidative stress and pulmonary fibrosis

(2012) Paul Cheresh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Lung Transplantation for Interstitial Lung Disease

(2012) Timothy P.M. Whelan   CLINICS IN CHEST MEDICINE

Fell-Muir lecture: connective tissue growth factor (CCN2) - a pernicious and pleiotropic player in the development of kidney fibrosis

(2012) Roger M. Mason   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Fasudil, a Rho-Kinase Inhibitor, Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice

(2012) Chunguo Jiang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Combination of roflumilast with a beta-2 adrenergic receptor agonist inhibits proinflammatory and profibrotic mediator release from human lung fibroblasts

(2012) Stacey L Tannheimer et al.   RESPIRATORY RESEARCH

Vasoactive intestinal peptide protects against ischemic brain damage induced by focal cerebral ischemia in rats

(2011) Jie Yang et al.   BRAIN RESEARCH

Pleiotropic effects of pitavastatin

(2011) Jean Davignon   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Idiopathic Pulmonary Fibrosis: Pathobiology of Novel Approaches to Treatment

(2011) Toby M. Maher   CLINICS IN CHEST MEDICINE

Modeling pulmonary fibrosis with bleomycin

(2011) Marios A. Mouratis et al.   CURRENT OPINION IN PULMONARY MEDICINE

MEK inhibition suppresses the development of lung fibrosis in the bleomycin model

(2011) Maria Galuppo et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Possible strategies for anti-fibrotic drug intervention in scleroderma

(2011) Andrew Leask   Journal of Cell Communication and Signaling

Expression analysis of Akt and MAPK signaling pathways in lung tissue of patients with idiopathic pulmonary fibrosis (IPF)

(2010) Katerina M. Antoniou et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Connective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases

(2010) Olav A. Gressner et al.   LIVER INTERNATIONAL

Pathophysiological relevance of NO signaling in the cardiovascular system: Novel insight from mice lacking all NO synthases

(2010) Masato Tsutsui et al.   PHARMACOLOGY & THERAPEUTICS

Statins Inhibit Angiotensin II/Smad Pathway and Related Vascular Fibrosis, by a TGF-β-Independent Process

(2010) Raúl Rodrigues Díez et al.   PLoS One

Simvastatin Decreases Lipopolysaccharide-induced Pulmonary Inflammation in Healthy Volunteers

(2009) Murali Shyamsundar et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen

(2009) Markella Ponticos et al.   ARTHRITIS AND RHEUMATISM

Atorvastatin inhibits inflammatory angiogenesis in mice through down regulation of VEGF, TNF-α and TGF-β1

(2009) F.A. Araújo et al.   BIOMEDICINE & PHARMACOTHERAPY

Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: anti-angiogenic actions possibly contributing to plaque stability

(2009) Marika Massaro et al.   CARDIOVASCULAR RESEARCH

New Mechanisms of Pulmonary Fibrosis

(2009) Robert M. Strieter et al.   CHEST

Pleiotropic Effects of Statins - Clinical Evidence

(2009) Vasilios Athyros et al.   CURRENT PHARMACEUTICAL DESIGN

Connective Tissue Growth Factor-(CTGF, CCN2) – A Marker, Mediator and Therapeutic Target for Renal Fibrosis

(2009) Mysore K. Phanish et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Oxidative stress in the pathogenesis of diffuse lung diseases: A review

(2009) E. Bargagli et al.   RESPIRATORY MEDICINE

Homocysteine modulates the effect of simvastatin on expression of ApoA-I and NF- B/iNOS

(2008) L. G. Mikael et al.   CARDIOVASCULAR RESEARCH

Oxidative Stress Alters Syndecan-1 Distribution in Lungs with Pulmonary Fibrosis

(2008) Corrine R. Kliment et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diallyl sulfide attenuates bleomycin-induced pulmonary fibrosis: Critical role of iNOS, NF-κB, TNF-α and IL-1β

(2008) Srinivasan Kalayarasan et al.   LIFE SCIENCES

Minimization of immunosuppression after lung transplantation: current trends

(2008) Pamela J. McShane et al.   TRANSPLANT INTERNATIONAL

The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

(2007) Antje Moeller et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Serum levels of oxidative stress as a marker of disease severity in idiopathic pulmonary fibrosis

(2006) Zoe D. Daniil et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS