Neurological Enhancement Effects of Melatonin against Brain Injury-Induced Oxidative Stress, Neuroinflammation, and Neurodegeneration via AMPK/CREB Signaling

LiCl Pretreatment Ameliorates Adolescent Methamphetamine Exposure-Induced Long-Term Alterations in Behavior and Hippocampal Ultrastructure in Adulthood in Mice

(2019) Peng Yan et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Human Lung Cell Pyroptosis Following Traumatic Brain Injury

(2019) Nadine Kerr et al.   Cells

Bone Marrow Derived Extracellular Vesicles Activate Osteoclast Differentiation in Traumatic Brain Injury Induced Bone Loss

(2019) Quante Singleton et al.   Cells

Anti-Inflammatory Effect of Sulforaphane on LPS-Activated Microglia Potentially through JNK/AP-1/NF-κB Inhibition and Nrf2/HO-1 Activation

(2019) Lalita Subedi et al.   Cells

Notoginsenoside R1 Ameliorates Diabetic Retinopathy through PINK1-Dependent Activation of Mitophagy

(2019) Ping Zhou et al.   Cells

Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling

(2019) Tahir Muhammad et al.   Nutrients

Hesperetin Confers Neuroprotection by Regulating Nrf2/TLR4/NF-κB Signaling in an Aβ Mouse Model

(2019) Muhammad Ikram et al.   MOLECULAR NEUROBIOLOGY

Involvement of AMP-activated protein kinase in neuroinflammation and neurodegeneration in the adult and developing brain

(2019) Mariko Saito et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Neuroprotective Effect of β-Lapachone in MPTP-Induced Parkinson’s Disease Mouse Model: Involvement of Astroglial p-AMPK/Nrf2/HO-1 Signaling Pathways

(2019) Jin-Sun Park et al.   Biomolecules & Therapeutics

Oxidative Stress in Neurodegenerative Diseases: From a Mitochondrial Point of View

(2019) Giovanna Cenini et al.   Oxidative Medicine and Cellular Longevity

Natural Dietary Supplementation of Curcumin Protects Mice Brains against Ethanol-Induced Oxidative Stress-Mediated Neurodegeneration and Memory Impairment via Nrf2/TLR4/RAGE Signaling

(2019) Muhammad Ikram et al.   Nutrients

Nicotinamide Improves Functional Recovery via Regulation of the RAGE/JNK/NF-κB Signaling Pathway after Brain Injury

(2019) Sayed Alam et al.   Journal of Clinical Medicine

Caffeine Modulates Cadmium-Induced Oxidative Stress, Neuroinflammation, and Cognitive Impairments by Regulating Nrf-2/HO-1 In Vivo and In Vitro

(2019) Amjad Khan et al.   Journal of Clinical Medicine

Activation of Nrf2/HO-1 Pathway and Human Atherosclerotic Plaque Vulnerability:an In Vitro and In Vivo Study

(2019) Fiorelli et al.   Cells

Protective Effects of Licochalcone A Ameliorates Obesity and Non-Alcoholic Fatty Liver Disease Via Promotion of the Sirt-1/AMPK Pathway in Mice Fed a High-Fat Diet

(2019) Chian-Jiun Liou et al.   Cells

The Effects of Sodium Dichloroacetate on Mitochondrial Dysfunction and Neuronal Death Following Hypoglycemia-Induced Injury

(2019) Kho et al.   Cells

Pinocembrin Protects from AGE-Induced Cytotoxicity and Inhibits Non-Enzymatic Glycation in Human Insulin

(2019) Borriello et al.   Cells

Phytomedicine-Based Potent Antioxidant, Fisetin Protects CNS-Insult LPS-Induced Oxidative Stress-Mediated Neurodegeneration and Memory Impairment

(2019) Ashfaq Ahmad et al.   Journal of Clinical Medicine

Intermittent Hypoxia Prevents Myocardial Mitochondrial Ca2+ Overload and Cell Death during Ischemia/Reperfusion: The Role of Reactive Oxygen Species

(2019) Jui-Chih Chang et al.   Cells

Metformin treatment prevents amyloid plaque deposition and memory impairment in APP/PS1 mice

(2018) Zhenri Ou et al.   BRAIN BEHAVIOR AND IMMUNITY

Melatonin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress

(2018) Yu Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Acute dose of melatonin via Nrf2 dependently prevents acute ethanol-induced neurotoxicity in the developing rodent brain

(2018) Tahir Ali et al.   Journal of Neuroinflammation

Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway

(2018) Min Gi Jo et al.   MOLECULAR NEUROBIOLOGY

Mild TBI and risk of Parkinson disease

(2018) Raquel C. Gardner et al.   NEUROLOGY

BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-κB and Activating PKA/CREB

(2018) Chuwen Li et al.   Frontiers in Pharmacology

Down-Regulation of Amyloid-β Through AMPK Activation by Inhibitors of GSK-3β in SH-SY5Y and SH-SY5Y-AβPP695 Cells

(2018) Zhiyou Cai et al.   JOURNAL OF ALZHEIMERS DISEASE

Ferulic Acid Rescues LPS-Induced Neurotoxicity via Modulation of the TLR4 Receptor in the Mouse Hippocampus

(2018) Shafiq Ur Rehman et al.   MOLECULAR NEUROBIOLOGY

Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies

(2018) Jennifer L. McGuire et al.   MOLECULAR PSYCHIATRY

Adiponectin homolog novel osmotin protects obesity/diabetes-induced NAFLD by upregulating AdipoRs/PPARα signaling in ob/ob and db/db transgenic mouse models

(2018) Ashfaq Ahmad et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Neuroprotective Effect of Quercetin Against the Detrimental Effects of LPS in the Adult Mouse Brain

(2018) Amjad Khan et al.   Frontiers in Pharmacology

AMPK activation: Role in the signaling pathways of neuroinflammation and neurodegeneration

(2017) Christina Alves Peixoto et al.   EXPERIMENTAL NEUROLOGY

Natural Dietary Supplementation of Anthocyanins via PI3K/Akt/Nrf2/HO-1 Pathways Mitigate Oxidative Stress, Neurodegeneration, and Memory Impairment in a Mouse Model of Alzheimer’s Disease

(2017) Tahir Ali et al.   MOLECULAR NEUROBIOLOGY

Enhanced neuroprotection of anthocyanin-loaded PEG-gold nanoparticles against Aβ 1-42 -induced neuroinflammation and neurodegeneration via the NF- K B /JNK/GSK3β signaling pathway

(2017) Min Ju Kim et al.   Nanomedicine-Nanotechnology Biology and Medicine

Activation of AMPK by OSU53 protects spinal cord neurons from oxidative stress

(2017) Jun Xu et al.   Oncotarget

Regulation of cyclic AMP response element-binding protein during neuroglial interactions

(2016) LiMei Qin et al.   JOURNAL OF NEUROCHEMISTRY

Traumatic brain injury decreases AMP-activated protein kinase activity and pharmacological enhancement of its activity improves cognitive outcome

(2016) Julia L. Hill et al.   JOURNAL OF NEUROCHEMISTRY

Cyclic AMP is a key regulator of M1 to M2a phenotypic conversion of microglia in the presence of Th2 cytokines

(2016) Mousumi Ghosh et al.   Journal of Neuroinflammation

JNK Signaling: Regulation and Functions Based on Complex Protein-Protein Partnerships

(2016) András Zeke et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Anthocyanin-Loaded PEG-Gold Nanoparticles Enhanced the Neuroprotection of Anthocyanins in an Aβ1–42 Mouse Model of Alzheimer’s Disease

(2016) Tahir Ali et al.   MOLECULAR NEUROBIOLOGY

Protective Effect of Lupeol Against Lipopolysaccharide-Induced Neuroinflammation via the p38/c-Jun N-Terminal Kinase Pathway in the Adult Mouse Brain

(2015) Haroon Badshah et al.   Journal of Neuroimmune Pharmacology

Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3β pathway in the mouse hippocampus

(2015) Tahir Ali et al.   JOURNAL OF PINEAL RESEARCH

Neuropsychology of Neuroendocrine Dysregulation after Traumatic Brain Injury

(2015) Josef Zihl et al.   Journal of Clinical Medicine

AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease

(2014) Tz-Chuen Ju et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2–ARE signaling pathway as a potential mechanism

(2014) Ke Ding et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative Stress and Its Significant Roles in Neurodegenerative Diseases and Cancer

(2014) Raynoo Thanan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Alteration in Synaptic Junction Proteins following Traumatic Brain Injury

(2014) Lucia Merlo et al.   JOURNAL OF NEUROTRAUMA

Melatonin mediates protective effects on inflammatory response induced by interleukin-1 beta in human mesenchymal stem cells

(2013) Xiaozhen Liu et al.   JOURNAL OF PINEAL RESEARCH

The role of melatonin in the cells of the innate immunity: a review

(2013) Juan R. Calvo et al.   JOURNAL OF PINEAL RESEARCH

Decreased neuroinflammation and increased brain energy homeostasis following environmental enrichment after mild traumatic brain injury is associated with improvement in cognitive function

(2013) Teresita L Briones et al.   Acta Neuropathologica Communications

Inhibition of c-Jun N-terminal kinase prevents blood–brain barrier disruption and normalizes the expression of tight junction proteins clautin-5 and ZO-1 in a rat model of subarachnoid hemorrhage

(2012) Duo Chen et al.   ACTA NEUROCHIRURGICA

Targeted Gene Inactivation of Calpain-1 Suppresses Cortical Degeneration Due to Traumatic Brain Injury and Neuronal Apoptosis Induced by Oxidative Stress

(2012) Kaori H. Yamada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lithium Reduces BACE1 Overexpression, Beta Amyloid Accumulation, and Spatial Learning Deficits in Mice with Traumatic Brain Injury

(2012) Fengshan Yu et al.   JOURNAL OF NEUROTRAUMA

Melatonin: Action as antioxidant and potential applications in human disease and aging

(2010) Dominique Bonnefont-Rousselot et al.   TOXICOLOGY

AMP-Activated Protein Kinase Activation by 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) Inhibits Palmitate-Induced Endothelial Cell Apoptosis Through Reactive Oxygen Species Suppression

(2008) Ji-Eun Kim et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Inhibition of carbon tetrachloride–mediated apoptosis and oxidative stress by melatonin in experimental liver fibrosis

(2008) M Ogeturk et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

AMP-activated protein kinase phosphorylates transcription factors of the CREB family

(2007) D. M. Thomson et al.   JOURNAL OF APPLIED PHYSIOLOGY