Hesperetin Confers Neuroprotection by Regulating Nrf2/TLR4/NF-κB Signaling in an Aβ Mouse Model

Urate inhibits microglia activation to protect neurons in an LPS-induced model of Parkinson’s disease

(2018) Li-Hui Bao et al.   Journal of Neuroinflammation

7-Deoxy-trans-dihydronarciclasine Reduces β-Amyloid and Ameliorates Memory Impairment in a Transgenic Model of Alzheimer’s Disease

(2018) Yoon Sun Chun et al.   MOLECULAR NEUROBIOLOGY

Adenosine Augmentation Evoked by an ENT1 Inhibitor Improves Memory Impairment and Neuronal Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease

(2018) Chia-Chia Lee et al.   MOLECULAR NEUROBIOLOGY

Bexarotene Modulates Retinoid-X-Receptor Expression and Is Protective Against Neurotoxic Endoplasmic Reticulum Stress Response and Apoptotic Pathway Activation

(2018) Yogita Dheer et al.   MOLECULAR NEUROBIOLOGY

Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway

(2018) Min Gi Jo et al.   MOLECULAR NEUROBIOLOGY

Dietary Vitamin E Status Dictates Oxidative Stress Outcomes by Modulating Effects of Fish Oil Supplementation in Alzheimer Disease Model APPswe/PS1dE9 Mice

(2018) Shengqi Dong et al.   MOLECULAR NEUROBIOLOGY

Anthocyanins Improve Hippocampus-Dependent Memory Function and Prevent Neurodegeneration via JNK/Akt/GSK3β Signaling in LPS-Treated Adult Mice

(2018) Muhammad Sohail Khan et al.   MOLECULAR NEUROBIOLOGY

Deficiency of Tenascin-C Alleviates Neuronal Apoptosis and Neuroinflammation After Experimental Subarachnoid Hemorrhage in Mice

(2018) Lei Liu et al.   MOLECULAR NEUROBIOLOGY

Oxidative stress and the amyloid beta peptide in Alzheimer’s disease

(2018) C. Cheignon et al.   Redox Biology

Melatonin Rescue Oxidative Stress-Mediated Neuroinflammation/ Neurodegeneration and Memory Impairment in Scopolamine-Induced Amnesia Mice Model

(2018) Tahir Muhammad et al.   Journal of Neuroimmune Pharmacology

TLR4 inhibitor TAK-242 attenuates the adverse neural effects of diet-induced obesity

(2018) V. Alexandra Moser et al.   Journal of Neuroinflammation

Effect of Exercise and Aβ Protein Infusion on Long-Term Memory-Related Signaling Molecules in Hippocampal Areas

(2018) Karim A. Alkadhi et al.   MOLECULAR NEUROBIOLOGY

Nootropic and Anti-Alzheimer’s Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer’s Neuropathology

(2018) Md. Sahab Uddin et al.   MOLECULAR NEUROBIOLOGY

Amyloid β1–42-Induced Rapid Zn2+ Influx into Dentate Granule Cells Attenuates Maintained LTP Followed by Retrograde Amnesia

(2018) Haruna Tamano et al.   MOLECULAR NEUROBIOLOGY

Natural Dietary Supplementation of Anthocyanins via PI3K/Akt/Nrf2/HO-1 Pathways Mitigate Oxidative Stress, Neurodegeneration, and Memory Impairment in a Mouse Model of Alzheimer’s Disease

(2017) Tahir Ali et al.   MOLECULAR NEUROBIOLOGY

Molecular Cloning and Expression of Osmotin in a Baculovirus-Insect System: Purified Osmotin Mitigates Amyloid-beta Deposition in Neuronal Cells

(2017) Noman Bin Abid et al.   Scientific Reports

Vanillic acid attenuates Aβ1-42-induced oxidative stress and cognitive impairment in mice

(2017) Faiz Ul Amin et al.   Scientific Reports

The role of astrocytes in amyloid production and Alzheimer's disease

(2017) Georgia R. Frost et al.   Open Biology

Involvement of Astrocytes in Alzheimer’s Disease from a Neuroinflammatory and Oxidative Stress Perspective

(2017) Rodrigo E. González-Reyes et al.   Frontiers in Molecular Neuroscience

Anti-Alzheimer’s Studies on β-Sitosterol Isolated from Polygonum hydropiper L.

(2017) Muhammad Ayaz et al.   Frontiers in Pharmacology

Anthocyanin-Loaded PEG-Gold Nanoparticles Enhanced the Neuroprotection of Anthocyanins in an Aβ1–42 Mouse Model of Alzheimer’s Disease

(2016) Tahir Ali et al.   MOLECULAR NEUROBIOLOGY

Anthocyanins control neuroinflammation and consequent memory dysfunction in mice exposed to lipopolysaccharide

(2016) Fabiano B. Carvalho et al.   MOLECULAR NEUROBIOLOGY

Quercetin Exerts Differential Neuroprotective Effects Against H2O2 and Aβ Aggregates in Hippocampal Neurons: the Role of Mitochondria

(2016) Juan A. Godoy et al.   MOLECULAR NEUROBIOLOGY

Anthocyanins Reversed D-Galactose-Induced Oxidative Stress and Neuroinflammation Mediated Cognitive Impairment in Adult Rats

(2016) Shafiq Ur Rehman et al.   MOLECULAR NEUROBIOLOGY

(−)-Epicatechin, a Natural Flavonoid Compound, Protects Astrocytes Against Hemoglobin Toxicity via Nrf2 and AP-1 Signaling Pathways

(2016) Xi Lan et al.   MOLECULAR NEUROBIOLOGY

Evaluation of oxidative stress in the brain of a transgenic mouse model of Alzheimer disease by in vivo electron paramagnetic resonance imaging

(2015) Akihiro Matsumura et al.   FREE RADICAL BIOLOGY AND MEDICINE

The emerging role of Nrf2 in mitochondrial function

(2015) Albena T. Dinkova-Kostova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative Stress in Patients with Alzheimer’s Disease: Effect of Extracts of Fermented Papaya Powder

(2015) Mario Barbagallo et al.   MEDIATORS OF INFLAMMATION

Sulforaphane Ameliorates Okadaic Acid-Induced Memory Impairment in Rats by Activating the Nrf2/HO-1 Antioxidant Pathway

(2015) Subhash Dwivedi et al.   MOLECULAR NEUROBIOLOGY

Amyloid cascade hypothesis: Pathogenesis and therapeutic strategies in Alzheimer's disease

(2015) Sagar H. Barage et al.   NEUROPEPTIDES

A review on Alzheimer's disease pathophysiology and its management: an update

(2015) Anil Kumar et al.   Pharmacological Reports

Osmotin attenuates amyloid beta-induced memory impairment, tau phosphorylation and neurodegeneration in the mouse hippocampus

(2015) Tahir Ali et al.   Scientific Reports

Posttreatment with 11-Keto-β-Boswellic Acid Ameliorates Cerebral Ischemia–Reperfusion Injury: Nrf2/HO-1 Pathway as a Potential Mechanism

(2014) Yi Ding et al.   MOLECULAR NEUROBIOLOGY

Current Animal Models of Alzheimer’s Disease: Challenges in Translational Research

(2014) Mar Cuadrado-Tejedor et al.   Frontiers in Neurology

Reactive Oxygen Species in Inflammation and Tissue Injury

(2013) Manish Mittal et al.   ANTIOXIDANTS & REDOX SIGNALING

Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer's disease-related pathology

(2013) J.-P. Michaud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting Synaptic Dysfunction in Alzheimer’s Disease Therapy

(2012) Robert Nisticò et al.   MOLECULAR NEUROBIOLOGY

Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential

(2011) Mark L. Hanke et al.   CLINICAL SCIENCE

TLR2 Is a Primary Receptor for Alzheimer's Amyloid   Peptide To Trigger Neuroinflammatory Activation

(2011) S. Liu et al.   JOURNAL OF IMMUNOLOGY

Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture

(2011) C J Garwood et al.   Cell Death & Disease

Current Views of Toll-Like Receptor Signaling Pathways

(2010) Masahiro Yamamoto et al.   Gastroenterology Research and Practice

Animal Models for Alzheimer's Disease and Frontotemporal Dementia: A Perspective

(2009) Jürgen Götz et al.   ASN Neuro

Innate immunity and neuroinflammation in the CNS: The role of microglia in Toll-like receptor-mediated neuronal injury

(2009) Seija Lehnardt   GLIA

Alzheimer's disease: synaptic dysfunction and Aβ

(2009) Ganesh M Shankar et al.   Molecular Neurodegeneration

Inflammation, microglia, and alzheimer's disease

(2009) Brent Cameron et al.   NEUROBIOLOGY OF DISEASE

Differential regulation of toll-like receptor mRNAs in amyloid plaque-associated brain tissue of aged APP23 transgenic mice

(2009) Stefanie Frank et al.   NEUROSCIENCE LETTERS

Neuroprotective effects of chronic hesperetin administration in mice

(2008) Eun Jeong Choi et al.   ARCHIVES OF PHARMACAL RESEARCH

Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal

(2008) Sung-Chun Tang et al.   EXPERIMENTAL NEUROLOGY

Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease

(2008) Jing-Ji Jin et al.   Journal of Neuroinflammation

Neuroprotective effects of hesperetin in mouse primary neurones are independent of CREB activation

(2008) Stephanie Rainey-Smith et al.   NEUROSCIENCE LETTERS