Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway
Authors
Keywords
Gintonin, Neuroprotection, Nrf2/HO-1 pathway, Parkinson’s disease, MPTP, Neuroinflammation
Journal
MOLECULAR NEUROBIOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2018-04-20
DOI
10.1007/s12035-018-1020-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Role of Autophagy in Parkinson’s Disease
- (2018) Silvia Cerri et al. CURRENT MEDICINAL CHEMISTRY
- Comparison of clinical features among Parkinson's disease subtypes: A large retrospective study in a single center
- (2018) Takuya Konno et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- α-synuclein (SNCA ) but not dynamin 3 (DNM3 ) influences age at onset of leucine-rich repeat kinase 2 (LRRK2) Parkinson's disease in Spain
- (2018) Rubén Fernández-Santiago et al. MOVEMENT DISORDERS
- Gintonin, a Ginseng-Derived Lysophosphatidic Acid Receptor Ligand, Attenuates Alzheimer's Disease-Related Neuropathies: Involvement of Non-Amyloidogenic Processing
- (2018) Sung Hee Hwang et al. JOURNAL OF ALZHEIMERS DISEASE
- Nrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson's disease
- (2017) Sara Moreira et al. EXPERIMENTAL NEUROLOGY
- Gintonin attenuates depressive-like behaviors associated with alcohol withdrawal in mice
- (2017) Hyeon-Joong Kim et al. JOURNAL OF AFFECTIVE DISORDERS
- 17β-Estradiol via SIRT1/Acetyl-p53/NF-kB Signaling Pathway Rescued Postnatal Rat Brain Against Acute Ethanol Intoxication
- (2017) Mehtab Khan et al. MOLECULAR NEUROBIOLOGY
- The SH-SY5Y cell line in Parkinson’s disease research: a systematic review
- (2017) Helena Xicoy et al. Molecular Neurodegeneration
- Neuroprotective effects of Kukoamine A on neurotoxin-induced Parkinson's model through apoptosis inhibition and autophagy enhancement
- (2017) XiaoLong Hu et al. NEUROPHARMACOLOGY
- Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways
- (2017) Wen-Fang Chen et al. PHYTOMEDICINE
- Neuroprotective Effect and Mechanism of Thiazolidinedione on Dopaminergic Neurons In Vivo and In Vitro in Parkinson’s Disease
- (2017) Yanqin Wang et al. PPAR Research
- Vanillic acid attenuates Aβ1-42-induced oxidative stress and cognitive impairment in mice
- (2017) Faiz Ul Amin et al. Scientific Reports
- Isobavachalcone Attenuates MPTP-Induced Parkinson's Disease in Mice by Inhibition of Microglial Activation through NF-κB Pathway
- (2017) Haoran Jing et al. PLoS One
- Nesfatin-1 protects dopaminergic neurons against MPP+/MPTP-induced neurotoxicity through the C-Raf–ERK1/2-dependent anti-apoptotic pathway
- (2017) Xiao-Li Shen et al. Scientific Reports
- Suppression of adiponectin receptor 1 promotes memory dysfunction and Alzheimer’s disease-like pathologies
- (2017) Min Woo Kim et al. Scientific Reports
- Melatonin Stimulates the SIRT1/Nrf2 Signaling Pathway Counteracting Lipopolysaccharide (LPS)-Induced Oxidative Stress to Rescue Postnatal Rat Brain
- (2016) Shahid Ali Shah et al. CNS Neuroscience & Therapeutics
- S-Glutathionylation of Keap1: a new role for glutathioneS-transferase pi in neuronal protection
- (2016) Andreia Neves Carvalho et al. FEBS LETTERS
- Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3
- (2016) Yan-Jie Guo et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Gintonin enhances performance of mice in rotarod test: Involvement of lysophosphatidic acid receptors and catecholamine release
- (2016) Byung-Hwan Lee et al. NEUROSCIENCE LETTERS
- Nrf2 mitigates LRRK2- and α-synuclein–induced neurodegeneration by modulating proteostasis
- (2016) Gaia Skibinski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neuroprotective effect of matrine on MPTP-induced Parkinson's disease and on Nrf2 expression
- (2016) Fanhua Meng et al. Oncology Letters
- Osmotin attenuates LPS-induced neuroinflammation and memory impairments via the TLR4/NFκB signaling pathway
- (2016) Haroon Badshah et al. Scientific Reports
- Sulforaphane protects against rotenone-induced neurotoxicity in vivo: Involvement of the mTOR, Nrf2 and autophagy pathways
- (2016) Qian Zhou et al. Scientific Reports
- Hippocampus-dependent cognitive enhancement induced by systemic gintonin administration
- (2016) Sungmin Kim et al. Journal of Ginseng Research
- Neuroprotective Effects of Salidroside in the MPTP Mouse Model of Parkinson’s Disease: Involvement of the PI3K/Akt/GSK3βPathway
- (2016) Wei Zhang et al. Parkinsons Disease
- Alpha-Synuclein in Parkinson’s Disease: From Pathogenetic Dysfunction to Potential Clinical Application
- (2016) Lingjia Xu et al. Parkinsons Disease
- Mitochondrial dysfunction in Parkinson’s disease
- (2016) Qingsong Hu et al. Translational Neurodegeneration
- Assessment of the Effects of MPTP and Paraquat on Dopaminergic Neurons and Microglia in the Substantia Nigra Pars Compacta of C57BL/6 Mice
- (2016) Richard Jay Smeyne et al. PLoS One
- Candidate genes for Parkinson disease: Lessons from pathogenesis
- (2015) Priscilla De Rosa et al. CLINICA CHIMICA ACTA
- Synaptic enhancement induced by gintonin via lysophosphatidic acid receptor activation in central synapses
- (2015) Hoyong Park et al. JOURNAL OF NEUROPHYSIOLOGY
- Oral Administration of Gintonin Attenuates Cholinergic Impairments by Scopolamine, Amyloid-β Protein, and Mouse Model of Alzheimer’s Disease
- (2015) Hyeon-Joong Kim et al. MOLECULES AND CELLS
- Gintonin stimulates gliotransmitter release in cortical primary astrocytes
- (2015) Hyunsook Kim et al. NEUROSCIENCE LETTERS
- Gintonin, a novel ginseng-derived lysophosphatidic acid receptor ligand, stimulates neurotransmitter release
- (2015) Sung-Hee Hwang et al. NEUROSCIENCE LETTERS
- Oxidative stress and Parkinson’s disease
- (2015) Javier Blesa et al. Frontiers in Neuroanatomy
- Tyrosine hydroxylase expression and activity in nigrostriatal dopaminergic neurons of MPTP-treated mice at the presymptomatic and symptomatic stages of parkinsonism
- (2014) Elena A. Kozina et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Oxidative Stress-Induced Signaling Pathways Implicated in the Pathogenesis of Parkinson’s Disease
- (2014) Georgia S. Gaki et al. NEUROMOLECULAR MEDICINE
- Parkinson disease: from pathology to molecular disease mechanisms
- (2013) David T. Dexter et al. FREE RADICAL BIOLOGY AND MEDICINE
- A quantitative study of α-synuclein pathology in fifteen cases of dementia associated with Parkinson disease
- (2013) Richard A. Armstrong et al. JOURNAL OF NEURAL TRANSMISSION
- Parkinson's disease in the nuclear age of neuroinflammation
- (2013) Yvonne M. Nolan et al. TRENDS IN MOLECULAR MEDICINE
- A Guide to Neurotoxic Animal Models of Parkinson's Disease
- (2013) K. Tieu Cold Spring Harbor Perspectives in Medicine
- Clinical Approach to Parkinson's Disease: Features, Diagnosis, and Principles of Management
- (2013) J. Massano et al. Cold Spring Harbor Perspectives in Medicine
- Mitochondria drive autophagy pathology via microtubule disassembly
- (2012) Daniela M. Arduíno et al. Autophagy
- Tauroursodeoxycholic Acid Prevents MPTP-Induced Dopaminergic Cell Death in a Mouse Model of Parkinson’s Disease
- (2012) M. Castro-Caldas et al. MOLECULAR NEUROBIOLOGY
- Gintonin, a ginseng-derived novel ingredient, evokes long-term potentiation through N-methyl-D-aspartic acid receptor activation: Involvement of LPA receptors
- (2012) Tae-Joon Shin et al. MOLECULES AND CELLS
- Effects of Sun Ginseng on Memory Enhancement and Hippocampal Neurogenesis
- (2012) Chang Hwan Lee et al. PHYTOTHERAPY RESEARCH
- Therapeutic Effect of Korean Red Ginseng on Inflammatory Cytokines in Rats with Focal Cerebral Ischemia/Reperfusion Injury
- (2011) Jong Seok Lee et al. AMERICAN JOURNAL OF CHINESE MEDICINE
- Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation
- (2011) Bobby Thomas et al. PLoS One
- Novel Glycolipoproteins from Ginseng
- (2011) Mi-Kyung Pyo et al. Journal of Ginseng Research
- Behavioral phenotyping of mouse models of Parkinson's disease
- (2010) Tonya N. Taylor et al. BEHAVIOURAL BRAIN RESEARCH
- PINK1 cleavage at position A103 by the mitochondrial protease PARL
- (2010) Emma Deas et al. HUMAN MOLECULAR GENETICS
- Mitochondrial dysfunction in Parkinson's disease
- (2009) Konstanze F. Winklhofer et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Redox Regulation of Cell Survival
- (2008) Dunyaporn Trachootham et al. ANTIOXIDANTS & REDOX SIGNALING
- Targets for neuroprotection in Parkinson's disease
- (2008) Talene A. Yacoubian et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- An open-label trial of Korean red ginseng as an adjuvant treatment for cognitive impairment in patients with Alzheimers disease
- (2008) J.-H. Heo et al. EUROPEAN JOURNAL OF NEUROLOGY
- Nrf2-induced antioxidant protection: A promising target to counteract ROS-mediated damage in neurodegenerative disease?
- (2008) Helga E. de Vries et al. FREE RADICAL BIOLOGY AND MEDICINE
- Neuroprotective effect of baicalein against MPTP neurotoxicity: Behavioral, biochemical and immunohistochemical profile
- (2008) Yinxia Cheng et al. NEUROSCIENCE LETTERS
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started