Anti-Inflammatory Effect of Sulforaphane on LPS-Activated Microglia Potentially through JNK/AP-1/NF-κB Inhibition and Nrf2/HO-1 Activation

Sulforaphane Inhibits Lipopolysaccharide-Induced Inflammation, Cytotoxicity, Oxidative Stress, and miR-155 Expression and Switches to Mox Phenotype through Activating Extracellular Signal-Regulated Kinase 1/2–Nuclear Factor Erythroid 2-Related Factor 2/Antioxidant Response Element Pathway in Murine Microglial Cells

(2018) Erden Eren et al.   Frontiers in Immunology

Activation of Nrf2/HO-1 Pathway by Nardochinoid C Inhibits Inflammation and Oxidative Stress in Lipopolysaccharide-Stimulated Macrophages

(2018) Jin-Fang Luo et al.   Frontiers in Pharmacology

The extracellular signal-regulated kinase 1/2 pathway in neurological diseases: A potential therapeutic target (Review)

(2017) Jing Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress

(2017) Eri Kubo et al.   Scientific Reports

The Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway as a Discovery Target in Stroke

(2016) Jing Sun et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician’s Expectation Be Matched by the Reality?

(2016) Christine A. Houghton et al.   Oxidative Medicine and Cellular Longevity

Anti-neuroinflammatory and neuroprotective effects of the Lindera neesiana fruit in vitro

(2016) Lalita Subedi et al.   PHYTOMEDICINE

Broccoli sprout extract prevents diabetic cardiomyopathy via Nrf2 activation in db/db T2DM mice

(2016) Zheng Xu et al.   Scientific Reports

Sulforaphane exerts anti-inflammatory effects against lipopolysaccharide-induced acute lung injury in mice through the Nrf2/ARE pathway

(2015) TIANJIE QI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Sulforaphane inhibits multiple inflammasomes through an Nrf2-independent mechanism

(2015) Allison J. Greaney et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neuroprotective Effect ofBrassica oleraceaSprouts Crude Juice in a Cellular Model of Alzheimer’s Disease

(2015) Alessandra Masci et al.   Oxidative Medicine and Cellular Longevity

Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation

(2015) Yang Bai et al.   Oxidative Medicine and Cellular Longevity

Tumour necrosis factor alpha-induced neuronal loss is mediated by microglial phagocytosis

(2014) Urte Neniskyte et al.   FEBS LETTERS

Neuroprotective Effects of Sulforaphane on Cholinergic Neurons in Mice with Alzheimer’s Disease-Like Lesions

(2014) Rui Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sulforaphane Inhibits TNF-α-Induced Adhesion Molecule Expression Through the Rho A/ROCK/NF-κB Signaling Pathway

(2014) Chi-Nan Hung et al.   JOURNAL OF MEDICINAL FOOD

TNF and MAP kinase signalling pathways

(2014) Guadalupe Sabio et al.   SEMINARS IN IMMUNOLOGY

Toll-like receptor 4 agonist, lipopolysaccharide, increases the expression levels of cytokines and chemokines in human peripheral blood mononuclear cells

(2014) DAN PU et al.   Experimental and Therapeutic Medicine

Kalopanaxsaponin A Exerts Anti-Inflammatory Effects in Lipopolysaccharide-Stimulated Microglia via Inhibition of JNK and NF-κB/AP-1 Pathways

(2013) Yeon-Hui Jeong et al.   Biomolecules & Therapeutics

Toll-like Receptor 4 (TLR4) Modulation by Synthetic and Natural Compounds: An Update

(2013) Francesco Peri et al.   JOURNAL OF MEDICINAL CHEMISTRY

Sulforaphane as a Potential Protective Phytochemical against Neurodegenerative Diseases

(2013) Andrea Tarozzi et al.   Oxidative Medicine and Cellular Longevity

Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages

(2013) Hong-Guang Chen et al.   International Journal of Surgery

Amelioration of Alzheimer’s disease by neuroprotective effect of sulforaphane in animal model

(2012) Hyunjin Vincent Kim et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Sulforaphane inhibits restenosis by suppressing inflammation and the proliferation of vascular smooth muscle cells

(2012) Jin-Sook Kwon et al.   ATHEROSCLEROSIS

Heme Oxygenase-1 Couples Activation of Mitochondrial Biogenesis to Anti-inflammatory Cytokine Expression

(2011) Claude A. Piantadosi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibition of Activator Protein-1 by Sulforaphane Involves Interaction with Cysteine in the cFos DNA-Binding Domain: Implications for Chemoprevention of UVB-Induced Skin Cancer

(2009) S. E. Dickinson et al.   CANCER RESEARCH

JNK signaling in apoptosis

(2008) D N Dhanasekaran et al.   ONCOGENE