Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies

Understanding the pathophysiology of depression: From monoamines to the neurogenesis hypothesis model - are we there yet?

(2018) Emmanuel Jesulola et al.   BEHAVIOURAL BRAIN RESEARCH

Dual-transmitter systems regulating arousal, attention, learning and memory

(2018) Sherie Ma et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Implantation of Neuronal Stem Cells Enhances Object Recognition without Increasing Neurogenesis after Lateral Fluid Percussion Injury in Mice

(2018) Laura B. Ngwenya et al.   Stem Cells International

Sertraline for Major Depression During the Year Following Traumatic Brain Injury

(2017) Jesse R. Fann et al.   JOURNAL OF HEAD TRAUMA REHABILITATION

Traumatic Brain Injury Induces Alterations in Cortical Glutamate Uptake without a Reduction in Glutamate Transporter-1 Protein Expression

(2017) Christopher R. Dorsett et al.   JOURNAL OF NEUROTRAUMA

Glutamate Neurotransmission in Rodent Models of Traumatic Brain Injury

(2017) Christopher R. Dorsett et al.   JOURNAL OF NEUROTRAUMA

Validating Multi-Dimensional Outcome Assessment Using the Traumatic Brain Injury Common Data Elements: An Analysis of the TRACK-TBI Pilot Study Sample

(2017) Lindsay D. Nelson et al.   JOURNAL OF NEUROTRAUMA

Plasticity in the Working Memory System: Life Span Changes and Response to Injury

(2017) Sean Froudist-Walsh et al.   NEUROSCIENTIST

Genetic biomarkers of posttraumatic epilepsy: A systematic review

(2017) Devyn Cotter et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Endocannabinoids: A Promising Impact for Traumatic Brain Injury

(2017) Lesley D. Schurman et al.   Frontiers in Pharmacology

Catecholamines and cognition after traumatic brain injury

(2016) Peter O. Jenkins et al.   BRAIN

Therapies negating neuroinflammation after brain trauma

(2016) Sarah Hellewell et al.   BRAIN RESEARCH

Genetic variation in neuronal glutamate transport genes and associations with posttraumatic seizure

(2016) Anne C. Ritter et al.   EPILEPSIA

Enduring changes in tonic GABA A receptor signaling in dentate granule cells after controlled cortical impact brain injury in mice

(2016) Jeffery A. Boychuk et al.   EXPERIMENTAL NEUROLOGY

Hippocampal GABAergic transmission: a new target for adenosine control of excitability

(2016) Diogo M. Rombo et al.   JOURNAL OF NEUROCHEMISTRY

Association of traumatic brain injury with subsequent neurological and psychiatric disease: a meta-analysis

(2016) David C. Perry et al.   JOURNAL OF NEUROSURGERY

Transition from Initial Hypoactivity to Hyperactivity in Cortical Layer V Pyramidal Neurons after Traumatic Brain InjuryIn Vivo

(2016) Xingjie Ping et al.   JOURNAL OF NEUROTRAUMA

Excitotoxicity and Metabolic Crisis Are Associated with Spreading Depolarizations in Severe Traumatic Brain Injury Patients

(2016) Jason M. Hinzman et al.   JOURNAL OF NEUROTRAUMA

Ex Vivo Tracing of NMDA and GABA-A Receptors in Rat Brain After Traumatic Brain Injury Using 18F-GE-179 and 18F-GE-194 Autoradiography

(2016) F. Lopez-Picon et al.   JOURNAL OF NUCLEAR MEDICINE

Traumatic brain injury decreases serotonin transporter expression in the rat cerebrum

(2016) Keiichi Abe et al.   NEUROLOGICAL RESEARCH

Purinergic receptors in psychiatric disorders

(2016) Ute Krügel   NEUROPHARMACOLOGY

Hypo-excitation across all cortical laminae defines intermediate stages of cortical neuronal dysfunction in diffuse traumatic brain injury

(2016) Benjamin J. Allitt et al.   NEUROSCIENCE

Epigenetic changes following traumatic brain injury and their implications for outcome, recovery and therapy

(2016) Victor S. Wong et al.   NEUROSCIENCE LETTERS

The Molecular Pathophysiology of Concussive Brain Injury – an Update

(2016) Garni Barkhoudarian et al.   Physical Medicine and Rehabilitation Clinics of North America

Sertraline for Preventing Mood Disorders Following Traumatic Brain Injury

(2016) Ricardo E. Jorge et al.   JAMA Psychiatry

Plasticity of Cortical Excitatory-Inhibitory Balance

(2015) Robert C. Froemke   Annual Review of Neuroscience

Randomized Controlled Trials in Adult Traumatic Brain Injury: A Review of Compliance to CONSORT Statement

(2015) Juan Lu et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Glutamate and GABA Imbalance Following Traumatic Brain Injury

(2015) Réjean M. Guerriero et al.   Current Neurology and Neuroscience Reports

Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development

(2015) Matthew L. Diamond et al.   EPILEPSIA

Is L-Lactate a Novel Signaling Molecule in the Brain?

(2015) Valentina Mosienko et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Speed of processing and strategic control of attention after traumatic brain injury

(2015) Alicia Rhian Dymowski et al.   JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY

Main path and byways: non-vesicular glutamate release by system xc−as an important modifier of glutamatergic neurotransmission

(2015) Ann Massie et al.   JOURNAL OF NEUROCHEMISTRY

Long-Term Consequences of Traumatic Brain Injury: Current Status of Potential Mechanisms of Injury and Neurological Outcomes

(2015) Helen M. Bramlett et al.   JOURNAL OF NEUROTRAUMA

Alterations in Cholinergic Pathways and Therapeutic Strategies Targeting Cholinergic System after Traumatic Brain Injury

(2015) Samuel S. Shin et al.   JOURNAL OF NEUROTRAUMA

Amantadine Effect on Perceptions of Irritability after Traumatic Brain Injury: Results of the Amantadine Irritability Multisite Study

(2015) Flora M. Hammond et al.   JOURNAL OF NEUROTRAUMA

Post-Acute Traumatic Brain Injury Rehabilitation: Effects on Outcome Measures and Life Care Costs

(2015) Grace S. Griesbach et al.   JOURNAL OF NEUROTRAUMA

Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy

(2015) Asami Kondo et al.   NATURE

Amantadine for Patients With Severe Traumatic Brain Injury

(2015) Scott D. Spritzer et al.   NEUROLOGIST

Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI)

(2015) Andrew I.R. Maas et al.   NEUROSURGERY

Neuroglial Transmission

(2015) Vidar Gundersen et al.   PHYSIOLOGICAL REVIEWS

Diagnosis and Management of Acute Concussion

(2015) Christopher Giza et al.   SEMINARS IN NEUROLOGY

Changes in the neurochemistry of athletes with repetitive brain trauma: preliminary results using localized correlated spectroscopy

(2015) Alexander P Lin et al.   Alzheimers Research & Therapy

Glycolysis and the significance of lactate in traumatic brain injury

(2015) Keri L. H. Carpenter et al.   Frontiers in Neuroscience

Brain Injury Impairs Working Memory and Prefrontal Circuit Function

(2015) Colin J. Smith et al.   Frontiers in Neurology

Traumatic Brain Injury Increases Cortical Glutamate Network Activity by Compromising GABAergic Control

(2014) David Cantu et al.   CEREBRAL CORTEX

Novel Approach to the Role of NMDA Receptors in Traumatic Brain Injury

(2014) Esther Shohami et al.   CNS & Neurological Disorders-Drug Targets

Lactate Storm Marks Cerebral Metabolism following Brain Trauma

(2014) Sanju Lama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Influence of Genetic Variants on Striatal Dopamine Transporter and D2 Receptor Binding after TB

(2014) Amy K Wagner et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Regulation of Hippocampal Synaptic Strength by Glial xCT

(2014) L. E. Williams et al.   JOURNAL OF NEUROSCIENCE

The Glasgow Coma Scale at 40 years: standing the test of time

(2014) Graham Teasdale et al.   LANCET NEUROLOGY

Genetic Data Sharing and Privacy

(2014) Marco D. Sorani et al.   NEUROINFORMATICS

Myoinositol and glutamate complex neurometabolite abnormality after mild traumatic brain injury

(2014) A. S. Kierans et al.   NEUROLOGY

Depression following adult, non-penetrating traumatic brain injury: A meta-analysis examining methodological variables and sample characteristics

(2014) A.J. Osborn et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Cortical spreading depression in traumatic brain injuries: Is there a role for astrocytes?

(2014) Daniel Torrente et al.   NEUROSCIENCE LETTERS

Amantadine Ameliorates Dopamine-Releasing Deficits and Behavioral Deficits in Rats after Fluid Percussion Injury

(2014) Eagle Yi-Kung Huang et al.   PLoS One

Reduced GABAergic Inhibition in the Basolateral Amygdala and the Development of Anxiety-Like Behaviors after Mild Traumatic Brain Injury

(2014) Camila P. Almeida-Suhett et al.   PLoS One

Complexity of dopamine metabolism

(2013) Johannes Meiser et al.   Cell Communication and Signaling

Lactate Receptor Sites Link Neurotransmission, Neurovascular Coupling, and Brain Energy Metabolism

(2013) K. H. Lauritzen et al.   CEREBRAL CORTEX

Half-molar sodium lactate infusion to prevent intracranial hypertensive episodes in severe traumatic brain injured patients: a randomized controlled trial

(2013) Carole Ichai et al.   INTENSIVE CARE MEDICINE

Traumatic Brain Injury

(2013) Geoffrey T. Manley et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Homeostatic Competition between Phasic and Tonic Inhibition

(2013) Xia Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cerebral Extracellular Lactate Increase is Predominantly Nonischemic in Patients with Severe Traumatic Brain Injury

(2013) Nathalie Sala et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Adenosine A2A Receptor Deficiency Alleviates Blast-Induced Cognitive Dysfunction

(2013) Ya-Lei Ning et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Association between cognitive impairments and anxiety disorders following traumatic brain injury

(2013) Kate Rachel Gould et al.   JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY

Effectiveness of Amantadine Hydrochloride in the Reduction of Chronic Traumatic Brain Injury Irritability and Aggression

(2013) Flora M. Hammond et al.   JOURNAL OF HEAD TRAUMA REHABILITATION

Toward an International Initiative for Traumatic Brain Injury Research

(2013) Patrizia Tosetti et al.   JOURNAL OF NEUROTRAUMA

Transforming Research and Clinical Knowledge in Traumatic Brain Injury Pilot: Multicenter Implementation of the Common Data Elements for Traumatic Brain Injury

(2013) John K. Yue et al.   JOURNAL OF NEUROTRAUMA

Challenges in the Development of Rodent Models of Mild Traumatic Brain Injury

(2013) Douglas S. DeWitt et al.   JOURNAL OF NEUROTRAUMA

Changing patterns in the epidemiology of traumatic brain injury

(2013) Bob Roozenbeek et al.   Nature Reviews Neurology

Animal models of traumatic brain injury

(2013) Ye Xiong et al.   NATURE REVIEWS NEUROSCIENCE

Lactate Modulates the Activity of Primary Cortical Neurons through a Receptor-Mediated Pathway

(2013) Luigi Bozzo et al.   PLoS One

Results of Phase 2 Safety and Feasibility Study of Treatment With Levetiracetam for Prevention of Posttraumatic Epilepsy

(2012) Pavel Klein et al.   ARCHIVES OF NEUROLOGY

Adenosine A2A receptors modulate glutamate uptake in cultured astrocytes and gliosomes

(2012) Marco Matos et al.   GLIA

γ-Aminobutyric Acid Type A (GABAA) Receptor α Subunits Play a Direct Role in SynapticVersusExtrasynaptic Targeting

(2012) Xia Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GABAA Receptor Regulation after Experimental Traumatic Brain Injury

(2012) Daniel J. Raible et al.   JOURNAL OF NEUROTRAUMA

Evaluation of late cognitive impairment and anxiety states following traumatic brain injury in mice: The effect of minocycline

(2012) Eleni Siopi et al.   NEUROSCIENCE LETTERS

Placebo-Controlled Trial of Amantadine for Severe Traumatic Brain Injury

(2012) Joseph T. Giacino et al.   NEW ENGLAND JOURNAL OF MEDICINE

Acute Minocycline Treatment Mitigates the Symptoms of Mild Blast-Induced Traumatic Brain Injury

(2012) Erzsebet Kovesdi et al.   Frontiers in Neurology

In Vitro Models of Traumatic Brain Injury

(2011) Barclay Morrison et al.   Annual Review of Biomedical Engineering

Symptom Complaints Following Reports of Blast Versus Non-Blast Mild TBI: Does Mechanism of Injury Matter?

(2011) Heather G. Belanger et al.   CLINICAL NEUROPSYCHOLOGIST

Alterations of GABAA and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy

(2011) Elena A. Kharlamov et al.   EPILEPSY RESEARCH

Substantia nigra vulnerability after a single moderate diffuse brain injury in the rat

(2011) Daniel R. van Bregt et al.   EXPERIMENTAL NEUROLOGY

Synaptic Reorganization of Inhibitory Hilar Interneuron Circuitry after Traumatic Brain Injury in Mice

(2011) R. F. Hunt et al.   JOURNAL OF NEUROSCIENCE

Traumatic Brain Injury in Adult Rats Causes Progressive Nigrostriatal Dopaminergic Cell Loss and Enhanced Vulnerability to the Pesticide Paraquat

(2011) Che Brown Hutson et al.   JOURNAL OF NEUROTRAUMA

Imipramine Treatment Improves Cognitive Outcome Associated with Enhanced Hippocampal Neurogenesis after Traumatic Brain Injury in Mice

(2011) Xiaodi Han et al.   JOURNAL OF NEUROTRAUMA

Re-Orientation of Clinical Research in Traumatic Brain Injury: Report of an International Workshop on Comparative Effectiveness Research

(2011) Andrew I.R. Maas et al.   JOURNAL OF NEUROTRAUMA

Cholinergic dysfunction after traumatic brain injury: Preliminary findings from a PET study

(2011) A. Ostberg et al.   NEUROLOGY

How Inhibition Shapes Cortical Activity

(2011) Jeffry S. Isaacson et al.   NEURON

The noradrenaline transporter as site of action for the anti-Parkinson drug amantadine

(2011) Christian Sommerauer et al.   NEUROPHARMACOLOGY

Towards a glutamate hypothesis of depression

(2011) Gerard Sanacora et al.   NEUROPHARMACOLOGY

Progressive loss of phasic, but not tonic, GABAA receptor-mediated inhibition in dentate granule cells in a model of post-traumatic epilepsy in rats

(2011) I. Pavlov et al.   NEUROSCIENCE

Adenosine A1 receptor gene variants associated with post-traumatic seizures after severe TBI

(2010) Amy K. Wagner et al.   EPILEPSY RESEARCH

A Randomized Controlled Trial of Antidepressant Continuation for Major Depression Following Traumatic Brain Injury

(2010) Mark J. Rapoport et al.   JOURNAL OF CLINICAL PSYCHIATRY

Impact of Early Administration of Sertraline on Cognitive and Behavioral Recovery in the First Year After Moderate to Severe Traumatic Brain Injury

(2010) James H. Baños et al.   JOURNAL OF HEAD TRAUMA REHABILITATION

Local Glutamate Level Dictates Adenosine A2A Receptor Regulation of Neuroinflammation and Traumatic Brain Injury

(2010) S. S. Dai et al.   JOURNAL OF NEUROSCIENCE

Memantine Preferentially Blocks Extrasynaptic over Synaptic NMDA Receptor Currents in Hippocampal Autapses

(2010) P. Xia et al.   JOURNAL OF NEUROSCIENCE

Focal Neuronal Damage in Patients with Neuropsychological Impairment after Diffuse Traumatic Brain Injury: Evaluation Using 11C-Flumazenil Positron Emission Tomography with Statistical Image Analysis

(2010) Nobuyuki Kawai et al.   JOURNAL OF NEUROTRAUMA

A Longitudinal Proton Magnetic Resonance Spectroscopy Study of Mild Traumatic Brain Injury

(2010) Ronald A. Yeo et al.   JOURNAL OF NEUROTRAUMA

Fluoxetine Increases Hippocampal Neurogenesis and Induces Epigenetic Factors But Does Not Improve Functional Recovery after Traumatic Brain Injury

(2010) Yonggang Wang et al.   JOURNAL OF NEUROTRAUMA

Increase of GABAA receptor-mediated tonic inhibition in dentate granule cells after traumatic brain injury

(2010) Zakaria Mtchedlishvili et al.   NEUROBIOLOGY OF DISEASE

Clinical trials in traumatic brain injury: Past experience and current developments

(2010) Andrew I. R. Maas et al.   Neurotherapeutics

A Randomized Controlled Trial of Sertraline for the Treatment of Depression in Persons With Traumatic Brain Injury

(2009) Teresa A. Ashman et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Adenosine Neuromodulation and Traumatic Brain Injury

(2009) T. Lusardi   Current Neuropharmacology

Psychiatric Disorders Following Traumatic Brain Injury

(2009) Rochelle Whelan-Goodinson et al.   JOURNAL OF HEAD TRAUMA REHABILITATION

Impact of Early Administration of Sertraline on Depressive Symptoms in the First Year after Traumatic Brain Injury

(2009) Thomas A. Novack et al.   JOURNAL OF NEUROTRAUMA

Spreading Depolarizations and Late Secondary Insults after Traumatic Brain Injury

(2009) Jed A. Hartings et al.   JOURNAL OF NEUROTRAUMA

Neurometabolite Concentrations in Gray and White Matter in Mild Traumatic Brain Injury: An 1H–Magnetic Resonance Spectroscopy Study

(2009) Charles Gasparovic et al.   JOURNAL OF NEUROTRAUMA

Neurometabolic Changes in the Acute Phase after Sports Concussions Correlate with Symptom Severity

(2009) Luke C. Henry et al.   JOURNAL OF NEUROTRAUMA

Prospective, Randomized, Single-Blinded Comparative Trial of Intravenous Levetiracetam Versus Phenytoin for Seizure Prophylaxis

(2009) Jerzy P. Szaflarski et al.   Neurocritical Care

Persistent working memory dysfunction following traumatic brain injury: Evidence for a time-dependent mechanism

(2009) M.M. Hoskison et al.   NEUROSCIENCE

Persistent cognitive dysfunction after traumatic brain injury: A dopamine hypothesis

(2009) James W. Bales et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Neuropsychiatric Problems After Traumatic Brain Injury: Unraveling the Silent Epidemic

(2009) Sandeep Vaishnavi et al.   PSYCHOSOMATICS

The Effects of Bromocriptine on Attention Deficits After Traumatic Brain Injury

(2008) John Whyte et al.   AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION

Time-dependent alterations of cholinergic markers after experimental traumatic brain injury

(2008) Cornelius K. Donat et al.   BRAIN RESEARCH

Calcium-Permeable AMPA Receptors Appear in Cortical Neurons after Traumatic Mechanical Injury and Contribute to Neuronal Fate

(2008) Jennifer M. Spaethling et al.   JOURNAL OF NEUROTRAUMA

Classification of Traumatic Brain Injury for Targeted Therapies

(2008) Kathryn E. Saatman et al.   JOURNAL OF NEUROTRAUMA

Cognitive functioning ten years following traumatic brain injury and rehabilitation.

(2008) Kristy Draper et al.   NEUROPSYCHOLOGY