Health Effects of Phenolic Compounds Found in Extra-Virgin Olive Oil, By-Products, and Leaf of Olea europaea L.

Health benefits of olive oil and its components: Impact on gut microbiota, and prevention of the risk of development of noncommunicable diseases

(2019) Mohsen Gavahian et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Natural Molecules for Healthy Lifestyles: Oleocanthal from Extra Virgin Olive Oil

(2019) Vera Francisco et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Hydroxytyrosol, Tyrosol and Derivatives and Their Potential Effects on Human Health

(2019) Karković Marković et al.   MOLECULES

Secoiridoids of olive and derivatives as potential coadjuvant drugs in cancer: A critical analysis of experimental studies

(2019) Marilena Celano et al.   PHARMACOLOGICAL RESEARCH

Precision Nutrition and the Microbiome, Part I: Current State of the Science

(2019) Mills et al.   Nutrients

Impact of Gut Microbiota Composition on Onset and Progression of Chronic Non-Communicable Diseases

(2019) Annalisa Noce et al.   Nutrients

Oleuropein, a component of extra virgin olive oil, lowers postprandial glycaemia in healthy subjects

(2018) Roberto Carnevale et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Human gut microbiome: hopes, threats and promises

(2018) Patrice D Cani   GUT

Improving in vivo conversion of oleuropein into hydroxytyrosol by oral granules containing probiotic Lactobacillus plantarum 299v and an Olea europaea standardized extract

(2018) Maria Aponte et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Antitumor Perspectives of Oleuropein and Its Metabolite Hydroxytyrosol: Recent Updates

(2018) Muhammad Imran et al.   JOURNAL OF FOOD SCIENCE

An effective HPLC-based approach for the evaluation of the content of total phenolic compounds transferred from olives to virgin olive oil during the olive milling process

(2018) Lorenzo Cecchi et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts

(2018) Ramón Estruch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Benefit of Oleuropein Aglycone for Alzheimer’s Disease by Promoting Autophagy

(2018) Joaquín G. Cordero et al.   Oxidative Medicine and Cellular Longevity

Oleuropein Aglycone Protects against MAO-A-Induced Autophagy Impairment and Cardiomyocyte Death through Activation of TFEB

(2018) Caterina Miceli et al.   Oxidative Medicine and Cellular Longevity

Influence of a diet enriched with virgin olive oil or butter on mouse gut microbiota and its correlation to physiological and biochemical parameters related to metabolic syndrome

(2018) Isabel Prieto et al.   PLoS One

A two-phase olive mill by-product (pâté) as a convenient source of phenolic compounds: Content, stability, and antiaging properties in cultured human fibroblasts

(2018) Lorenzo Cecchi et al.   Journal of Functional Foods

MOSH Syndrome (Male Obesity Secondary Hypogonadism): Clinical Assessment and Possible Therapeutic Approaches

(2018) Antonino De Lorenzo et al.   Nutrients

Current Disease-Targets for Oleocanthal as Promising Natural Therapeutic Agent

(2018) Antonio Segura-Carretero et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Administration of Minor Polar Compound-Enriched Extra Virgin Olive Oil Decreases Platelet Aggregation and the Plasma Concentration of Reduced Homocysteine in Rats

(2018) Raffaella Priora et al.   JOURNAL OF NUTRITION

From extraction of valuable compounds to health promoting benefits of olive leaves through bioaccessibility, bioavailability and impact on gut microbiota

(2018) Tihana Žugčić et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Oleuropein, the Main Polyphenol of Olea europaea Leaf Extract, Has an Anti-Cancer Effect on Human BRAF Melanoma Cells and Potentiates the Cytotoxicity of Current Chemotherapies

(2018) Jessica Ruzzolini et al.   Nutrients

Oleuropein aglycone attenuates the pro-angiogenic phenotype of senescent fibroblasts: A functional study in endothelial cells

(2018) Francesca Margheri et al.   Journal of Functional Foods

Identification of hydroxytyrosyl oleate, a derivative of hydroxytyrosol with anti-inflammatory properties, in olive oil by-products

(2018) Pierluigi Plastina et al.   FOOD CHEMISTRY

Lipophilization of Hydroxytyrosol-Enriched Fractions from Olea europaea L. Byproducts and Evaluation of the in Vitro Effects on a Model of Colorectal Cancer Cells

(2017) Roberta Bernini et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Recovery and stability over time of phenolic fractions by an industrial filtration system of olive mill wastewaters: a three-year study

(2017) Maria Bellumori et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Changes in Gut Microbiota Linked to a Reduction in Systolic Blood Pressure in Spontaneously Hypertensive Rats Fed an Extra Virgin Olive Oil-Enriched Diet

(2017) Marina Hidalgo et al.   PLANT FOODS FOR HUMAN NUTRITION

Oleocanthal-rich extra virgin olive oil demonstrates acute anti-platelet effects in healthy men in a randomized trial

(2017) Karan Agrawal et al.   Journal of Functional Foods

Effects of Olive Oil Phenolic Compounds on Inflammation in the Prevention and Treatment of Coronary Artery Disease

(2017) Priscilla Souza et al.   Nutrients

Extra Virgin Olive Oil and Cardiovascular Diseases: Benefits for Human Health

(2017) Cristina Nocella et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Anti-inflammatory Activity of Extra Virgin Olive Oil Polyphenols: Which Role in the Prevention and Treatment of Immune-Mediated Inflammatory Diseases?

(2017) Carmela Santangelo et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Olive Oil-related Anti-inflammatory Effects on Atherosclerosis: Potential Clinical Implications

(2017) Tanakal Wongwarawipat et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans

(2016) Ron Sender et al.   CELL

An environmentally friendly process for the production of extracts rich in phenolic antioxidants from Olea europaea L. and Cynara scolymus L. matrices

(2016) Annalisa Romani et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

A review: benefit and bioactive properties of olive (Olea europaea L.) leaves

(2016) Mehmet Musa Özcan et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

Extra virgin olive oil phenolic extracts counteract the pro-oxidant effect of dietary oxidized lipids in human intestinal cells

(2016) Alessandra Incani et al.   FOOD AND CHEMICAL TOXICOLOGY

Improved bioaccessibility and antioxidant capacity of olive leaf ( Olea europaea L.) polyphenols through biosorption on Saccharomyces cerevisiae

(2016) Hanène Jilani et al.   INDUSTRIAL CROPS AND PRODUCTS

The Polyphenol Oleuropein Aglycone Modulates the PARP1-SIRT1 Interplay: An In Vitro and In Vivo Study

(2016) Ilaria Luccarini et al.   JOURNAL OF ALZHEIMERS DISEASE

Analysis of free hydroxytyrosol in human plasma following the administration of olive oil

(2016) Antoni Pastor et al.   JOURNAL OF CHROMATOGRAPHY A

Oleuropein attenuates the progression of heart failure in rats by antioxidant and antiinflammatory effects

(2016) Zeinab Janahmadi et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The biological activities of natural lignans from olives and virgin olive oils: A review

(2016) Alicia López-Biedma et al.   Journal of Functional Foods

Influence of Phenol-Enriched Olive Oils on Human Intestinal Immune Function

(2016) Sandra Martín-Peláez et al.   Nutrients

Impact of Mediterranean diet on metabolic syndrome, cancer and longevity

(2016) Nicola Di Daniele et al.   Oncotarget

Sustainability, Innovation, and Green Chemistry in the Production and Valorization of Phenolic Extracts from Olea europaea L.

(2016) Annalisa Romani et al.   Sustainability

A comprehensive meta-analysis on evidence of Mediterranean diet and cardiovascular disease: Are individual components equal?

(2015) Giuseppe Grosso et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: a mechanistic insight

(2015) Stefania Rigacci et al.   Oncotarget

Effect of stoned olive pomace on rumen microbial communities and polyunsaturated fatty acid biohydrogenation: an in vitrostudy

(2014) Grazia Pallara et al.   BMC Veterinary Research

Oleocanthal, a Phenolic Derived from Virgin Olive Oil: A Review of the Beneficial Effects on Inflammatory Disease

(2014) Lisa Parkinson et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Influence of Olive Leaf Processing on the Bioaccessibility of Bioactive Polyphenols

(2014) Margarita H. Ahmad-Qasem et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Oleuropein prevents doxorubicin-induced cardiomyopathy interfering with signaling molecules and cardiomyocyte metabolism

(2014) Ioanna Andreadou et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Effects of Italian Mediterranean organic diet vs. low-protein diet in nephropathic patients according to MTHFR genotypes

(2014) Nicola Di Daniele et al.   JOURNAL OF NEPHROLOGY

Homocysteine, cysteine, folate and vitamin B12 status in type 2 diabetic patients with chronic kidney disease

(2014) Anna Pastore et al.   JOURNAL OF NEPHROLOGY

Faecal microbial metabolism of olive oil phenolic compounds: In vitro and in vivo approaches

(2014) Juana I. Mosele et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Fractionation of olive mill wastewaters by membrane separation techniques

(2013) Alfredo Cassano et al.   JOURNAL OF HAZARDOUS MATERIALS

Human absorption and metabolism of oleuropein and hydroxytyrosol ingested as olive (Olea europaeaL.) leaf extract

(2013) Martin de Bock et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Synthesis and DPPH radical scavenging activity of novel compounds obtained from tyrosol and cinnamic acid derivatives

(2013) Maurizio Barontini et al.   NEW JOURNAL OF CHEMISTRY

Protective role of the Mediterranean diet on several cardiovascular risk factors: Evidence from Sicily, southern Italy

(2013) G. Grosso et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Olive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover Trial

(2013) Martin de Bock et al.   PLoS One

Body composition changes and cardiometabolic benefits of a balanced Italian Mediterranean Diet in obese patients with metabolic syndrome

(2012) Nicola Di Daniele et al.   ACTA DIABETOLOGICA

Dietary Phenolic Acids Act as Effective Antioxidants in Membrane Models and in Cultured Cells, Exhibiting Proapoptotic Effects in Leukaemia Cells

(2012) Laura Zambonin et al.   Oxidative Medicine and Cellular Longevity

Bioconversion of oleuropein to hydroxytyrosol by lactic acid bacteria

(2012) M. M. Santos et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Comparison of standardised dietary folate intake across ten countries participating in the European Prospective Investigation into Cancer and Nutrition

(2011) Jin Young Park et al.   BRITISH JOURNAL OF NUTRITION

Aβ(1-42) Aggregates into Non-Toxic Amyloid Assemblies in the Presence of the Natural Polyphenol Oleuropein Aglycon

(2011) Stefania Rigacci et al.   Current Alzheimer Research

Antimicrobial, antioxidant and anti-inflammatory phenolic activities in extra virgin olive oil

(2011) S Cicerale et al.   CURRENT OPINION IN BIOTECHNOLOGY

Randomized controlled study of the urinary excretion of biophenols following acute and chronic intake of olive leaf supplements

(2011) Megan Kendall et al.   FOOD CHEMISTRY

Unusual Pungency from Extra-Virgin Olive Oil Is Attributable to Restricted Spatial Expression of the Receptor of Oleocanthal

(2011) C. Peyrot des Gachons et al.   JOURNAL OF NEUROSCIENCE

The postprandial inflammatory response after ingestion of heated oils in obese persons is reduced by the presence of phenol compounds

(2011) A. Perez-Herrera et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Fruit, vegetables, and olive oil and risk of coronary heart disease in Italian women: the EPICOR Study

(2010) Benedetta Bendinelli et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The Effects of Italian Mediterranean Organic Diet (IMOD) on Health Status

(2010) A. De Lorenzo et al.   CURRENT PHARMACEUTICAL DESIGN

Synthesis of a novel ester of hydroxytyrosol and α-lipoic acid exhibiting an antiproliferative effect on human colon cancer HT-29 cells

(2010) Roberta Bernini et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cytoprotective effects of olive mill wastewater extract and its main constituent hydroxytyrosol in PC12 cells

(2010) Sebastian Schaffer et al.   PHARMACOLOGICAL RESEARCH

Recovery and concentration of polyphenols from olive mill wastewaters by integrated membrane system

(2010) E. Garcia-Castello et al.   WATER RESEARCH

Sensory Characterization of the Irritant Properties of Oleocanthal, a Natural Anti-Inflammatory Agent in Extra Virgin Olive Oils

(2009) S. Cicerale et al.   CHEMICAL SENSES

Antimicrobial activity of commercial Olea europaea (olive) leaf extract

(2009) Aurelia N. Sudjana et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Olive Phenolics Increase Glutathione Levels in Healthy Volunteers

(2009) Francesco Visioli et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antidiabetic and Antioxidant Effects of Hydroxytyrosol and Oleuropein from Olive Leaves in Alloxan-Diabetic Rats

(2009) Hedya Jemai et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin☆

(2009) Stefania Rigacci et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Mediterranean diet, culture and heritage: challenges for a new conception

(2009) F Xavier Medina   PUBLIC HEALTH NUTRITION

Platelets: Inflammatory Firebugs of Vascular Walls

(2008) Andreas E. May et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The lectin-like oxidized low-density-lipoprotein receptor: a pro-inflammatory factor in vascular disease

(2008) Sarah Dunn et al.   BIOCHEMICAL JOURNAL

Convenient Synthesis of Hydroxytyrosol and Its Lipophilic Derivatives from Tyrosol or Homovanillyl Alcohol

(2008) Roberta Bernini et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

2-Arylhydroxytyrosol Derivatives via Suzuki−Miyaura Cross-Coupling

(2008) Roberta Bernini et al.   ORGANIC LETTERS

Endothelial function and inflammation in coronary artery disease

(2005) D Tousoulis et al.   POSTGRADUATE MEDICAL JOURNAL