The Roles of YAP/TAZ and the Hippo Pathway in Healthy and Diseased Skin
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Title
The Roles of YAP/TAZ and the Hippo Pathway in Healthy and Diseased Skin
Authors
Keywords
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Journal
Cells
Volume 8, Issue 5, Pages 411
Publisher
MDPI AG
Online
2019-05-07
DOI
10.3390/cells8050411
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Note: Only part of the references are listed.- Anti-proliferative and anti-migratory effects of a novel YAP-TEAD interaction inhibitor identified using in silico molecular docking
- (2019) Sarah Smith et al. JOURNAL OF MEDICINAL CHEMISTRY
- Somatic hypermutation of the YAP oncogene in a human cutaneous melanoma
- (2019) Xiaomeng Zhang et al. MOLECULAR CANCER RESEARCH
- Topical kinase inhibitors induce regression of cutaneous squamous cell carcinoma
- (2019) Xiaoping Yang et al. EXPERIMENTAL DERMATOLOGY
- Patterning of human epidermal stem cells on undulating elastomer substrates reflects differences in cell stiffness
- (2019) Seyedeh Atefeh Mobasseri et al. Acta Biomaterialia
- A shift from papillary to reticular fibroblasts enables tumour–stroma interaction and invasion
- (2018) Marieke Hogervorst et al. BRITISH JOURNAL OF CANCER
- YAP/TAZ regulates TGF-β/Smad3 signaling by induction of Smad7 via AP-1 in human skin dermal fibroblasts
- (2018) Zhaoping Qin et al. Cell Communication and Signaling
- YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
- (2018) Shiro Yui et al. Cell Stem Cell
- Dynamic Fluctuations in Subcellular Localization of the Hippo Pathway Effector Yorkie In Vivo
- (2018) Samuel A. Manning et al. CURRENT BIOLOGY
- The Emerging Therapeutic Landscape of Advanced Melanoma
- (2018) Vanessa Henriques et al. CURRENT PHARMACEUTICAL DESIGN
- A peek into cancer-associated fibroblasts: origins, functions and translational impact
- (2018) Valerie S. LeBleu et al. Disease Models & Mechanisms
- dNTP metabolism links mechanical cues and YAP/TAZ to cell growth and oncogene‐induced senescence
- (2018) Giulia Santinon et al. EMBO JOURNAL
- YAP and TAZ are essential for basal and squamous cell carcinoma initiation
- (2018) Maud Debaugnies et al. EMBO REPORTS
- Homeostasis, regeneration and tumour formation in the mammalian epidermis
- (2018) Daria Belokhvostova et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- The Hippo pathway effector proteins YAP and TAZ have both distinct and overlapping functions in the cell
- (2018) Steven W. Plouffe et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Claudin-18–mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis
- (2018) Beiyun Zhou et al. JOURNAL OF CLINICAL INVESTIGATION
- Fibroblast heterogeneity: implications for human disease
- (2018) Magnus D. Lynch et al. JOURNAL OF CLINICAL INVESTIGATION
- 1354 Spatial and single-cell transcriptional profiling identifies functionally distinct human dermal fibroblast subpopulations
- (2018) C. Philippeos et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin
- (2018) Tracy Tabib et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Caspase-3 Regulates YAP-Dependent Cell Proliferation and Organ Size
- (2018) Yahav Yosefzon et al. MOLECULAR CELL
- Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer
- (2018) Yejing Ge et al. NATURE REVIEWS GENETICS
- The NDR/LATS protein kinases in immunology and cancer biology
- (2018) Ahmad A.D. Sharif et al. SEMINARS IN CANCER BIOLOGY
- Epidermal YAP activity drives canonical WNT16/β-catenin signaling to promote keratinocyte proliferation in vitro and in the murine skin
- (2018) Veronica Mendoza-Reinoso et al. Stem Cell Research
- Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
- (2018) Emanuel Rognoni et al. TRENDS IN CELL BIOLOGY
- Crosstalk between YAP/TAZ and Notch Signaling
- (2018) Antonio Totaro et al. TRENDS IN CELL BIOLOGY
- RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73
- (2018) Angelos Papaspyropoulos et al. Nature Communications
- Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner
- (2018) Yoonmi Lee et al. Nature Communications
- YAP-Induced PD-L1 Expression Drives Immune Evasion in BRAFi-Resistant Melanoma
- (2018) Min Hwan Kim et al. Cancer Immunology Research
- Quantitative Analysis Reveals that Actin and Src-Family Kinases Regulate Nuclear YAP1 and Its Export
- (2018) Nil Ege et al. Cell Systems
- Targeting the Hippo Pathway and Cancer through the TEAD Family of Transcription Factors
- (2018) et al. Cancers
- Interplay between YAP/TAZ and Metabolism
- (2018) Ja Hyun Koo et al. Cell Metabolism
- YAP‐TEAD signaling promotes basal cell carcinoma development via a c‐JUN/AP1 axis
- (2018) Dejan Maglic et al. EMBO JOURNAL
- Melanoma
- (2018) Dirk Schadendorf et al. LANCET
- Fibroblast state switching orchestrates dermal maturation and wound healing
- (2018) Emanuel Rognoni et al. Molecular Systems Biology
- Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4
- (2018) Francesca Zanconato et al. NATURE MEDICINE
- Yes-associated protein promotes the abnormal proliferation of psoriatic keratinocytes via an amphiregulin dependent pathway
- (2018) Jinjing Jia et al. Scientific Reports
- YAP drives cutaneous squamous cell carcinoma formation and progression
- (2018) Zoé Vincent-Mistiaen et al. eLife
- The Hippo Pathway: Biology and Pathophysiology
- (2018) Shenghong Ma et al. Annual Review of Biochemistry
- Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast Aging
- (2018) Marion Claudia Salzer et al. CELL
- Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy
- (2018) Thomas Bertero et al. Cell Metabolism
- Hippo pathway inhibition by blocking the YAP/TAZ–TEAD interface: a patent review
- (2018) James J. Crawford et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- YAPping about and not forgetting TAZ
- (2018) Bernard A. Callus et al. FEBS LETTERS
- SRC tyrosine kinase activates the YAP/TAZ axis and thereby drives tumor growth and metastasis
- (2018) John M. Lamar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enigma proteins regulate YAP mechanotransduction
- (2018) Ahmed Elbediwy et al. JOURNAL OF CELL SCIENCE
- Stem cell dynamics, migration and plasticity during wound healing
- (2018) Sophie Dekoninck et al. NATURE CELL BIOLOGY
- Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine
- (2018) Iván M. Moya et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Plau and Tgfbr3 are YAP-regulated genes that promote keratinocyte proliferation
- (2018) Susan M. Corley et al. Cell Death & Disease
- Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
- (2018) Chae Ho Lim et al. Nature Communications
- Mediated nuclear import and export of TAZ and the underlying molecular requirements
- (2018) Michael Kofler et al. Nature Communications
- Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution
- (2018) Jeffrey B. Cheng et al. Cell Reports
- Mutual dependence of the MRTF–SRF and YAP–TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics
- (2017) Charles T. Foster et al. GENES & DEVELOPMENT
- Transcriptional integration of mitogenic and mechanical signals by Myc and YAP
- (2017) Ottavio Croci et al. GENES & DEVELOPMENT
- Epidermal YAP2-5SA-ΔC Drives β-Catenin Activation to Promote Keratinocyte Proliferation in Mouse Skin In Vivo
- (2017) Bassem Akladios et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Targeting Transcriptional Enhanced Associate Domains (TEADs)
- (2017) Floriane Gibault et al. JOURNAL OF MEDICINAL CHEMISTRY
- Stromal microenvironment in type VII collagen-deficient skin: The ground for squamous cell carcinoma development
- (2017) Liliana Guerra et al. MATRIX BIOLOGY
- Substance P accelerates wound healing in type 2 diabetic mice through endothelial progenitor cell mobilization and Yes-associated protein activation
- (2017) Jihyun Um et al. Molecular Medicine Reports
- Tissue-scale coordination of cellular behaviour promotes epidermal wound repair in live mice
- (2017) Sangbum Park et al. NATURE CELL BIOLOGY
- Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties
- (2017) Giacomo Donati et al. NATURE CELL BIOLOGY
- Positive regulatory interactions between YAP and Hedgehog signalling in skin homeostasis and BCC development in mouse skin in vivo
- (2017) Bassem Akladios et al. PLoS One
- Regeneration of fat cells from myofibroblasts during wound healing
- (2017) Maksim V. Plikus et al. SCIENCE
- Neoplastic Multifocal Skin Lesions: Biology, Etiology, and Targeted Therapies for Nonmelanoma Skin Cancers
- (2017) Ana R. Fernandes et al. SKIN PHARMACOLOGY AND PHYSIOLOGY
- Common and Distinctive Functions of the Hippo Effectors Taz and Yap in Skeletal Muscle Stem Cell Function
- (2017) Congshan Sun et al. STEM CELLS
- A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells
- (2017) Gernot Walko et al. Nature Communications
- 3D microniches reveal the importance of cell size and shape
- (2017) Min Bao et al. Nature Communications
- Defining stem cell dynamics and migration during wound healing in mouse skin epidermis
- (2017) Mariaceleste Aragona et al. Nature Communications
- YAP/TAZ link cell mechanics to Notch signalling to control epidermal stem cell fate
- (2017) Antonio Totaro et al. Nature Communications
- YAP regulates cell mechanics by controlling focal adhesion assembly
- (2017) Giorgia Nardone et al. Nature Communications
- Inhibition of YAP function overcomes BRAF inhibitor resistance in melanoma cancer stem cells
- (2017) Matthew L. Fisher et al. Oncotarget
- Yes-Associated Protein (YAP) Promotes Tumorigenesis in Melanoma Cells Through Stimulation of Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1)
- (2017) Huizi Xiong et al. Scientific Reports
- YAP Regulates Actin Dynamics through ARHGAP29 and Promotes Metastasis
- (2017) Yiting Qiao et al. Cell Reports
- A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis
- (2017) Ajay Mishra et al. eLife
- Actomyosin contractility provokes contact inhibition in E-cadherin-ligated keratinocytes
- (2017) Hiroaki Hirata et al. Scientific Reports
- Cutaneous Squamous Cell Carcinoma: A Review of High-Risk and Metastatic Disease
- (2016) Kyle A. Burton et al. AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
- YAP and TAZ in epithelial stem cells: A sensor for cell polarity, mechanical forces and tissue damage
- (2016) Ahmed Elbediwy et al. BIOESSAYS
- YAP/TAZ at the Roots of Cancer
- (2016) Francesca Zanconato et al. CANCER CELL
- Wnt Signaling Promotes Breast Cancer by Blocking ITCH-Mediated Degradation of YAP/TAZ Transcriptional Coactivator WBP2
- (2016) Shen Kiat Lim et al. CANCER RESEARCH
- New perspectives on role of tumor microenvironment in progression of cutaneous squamous cell carcinoma
- (2016) Liisa Nissinen et al. CELL AND TISSUE RESEARCH
- YAP/TAZ as therapeutic targets in cancer
- (2016) Francesca Zanconato et al. CURRENT OPINION IN PHARMACOLOGY
- Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing
- (2016) Emanuel Rognoni et al. DEVELOPMENT
- Integrin signalling regulates YAP and TAZ to control skin homeostasis
- (2016) Ahmed Elbediwy et al. DEVELOPMENT
- Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling
- (2016) Edwige Roy et al. EMBO JOURNAL
- Mechanisms of Hippo pathway regulation
- (2016) Zhipeng Meng et al. GENES & DEVELOPMENT
- αE-catenin inhibits a Src–YAP1 oncogenic module that couples tyrosine kinases and the effector of Hippo signaling pathway
- (2016) Peng Li et al. GENES & DEVELOPMENT
- Mimicking the topography of the epidermal–dermal interface with elastomer substrates
- (2016) Priyalakshmi Viswanathan et al. Integrative Biology
- YAP Nuclear Localization in the Absence of Cell-Cell Contact Is Mediated by a Filamentous Actin-dependent, Myosin II- and Phospho-YAP-independent Pathway during Extracellular Matrix Mechanosensing
- (2016) Arupratan Das et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Yes-Associated Protein Contributes to the Development of Human Cutaneous Squamous Cell Carcinoma via Activation of RAS
- (2016) Jinjing Jia et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Defining the cellular lineage hierarchy in the interfollicular epidermis of adult skin
- (2016) Aiko Sada et al. NATURE CELL BIOLOGY
- Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway
- (2016) PuiYee Chan et al. Nature Chemical Biology
- RAC-LATS1/2 signaling regulates YAP activity by switching between the YAP-binding partners TEAD4 and RUNX3
- (2016) J-W Jang et al. ONCOGENE
- Palmitoylation of TEAD Transcription Factors Is Required for Their Stability and Function in Hippo Pathway Signaling
- (2016) Cameron L. Noland et al. STRUCTURE
- Tead and AP1 Coordinate Transcription and Motility
- (2016) Xiangfan Liu et al. Cell Reports
- Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity
- (2016) Simon Joost et al. Cell Systems
- Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis
- (2015) Fei Liu et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Alternative Wnt Signaling Activates YAP/TAZ
- (2015) Hyun Woo Park et al. CELL
- Molecular architecture and function of the hemidesmosome
- (2015) Gernot Walko et al. CELL AND TISSUE RESEARCH
- Basal Cell Carcinoma Preferentially Arises from Stem Cells within Hair Follicle and Mechanosensory Niches
- (2015) Shelby C. Peterson et al. Cell Stem Cell
- Management of high-risk and advanced basal cell carcinoma
- (2015) S. Puig et al. Clinical & Translational Oncology
- Identification of Happyhour/MAP4K as Alternative Hpo/Mst-like Kinases in the Hippo Kinase Cascade
- (2015) Yonggang Zheng et al. DEVELOPMENTAL CELL
- Distinct Polarity Cues Direct Taz/Yap and TGFβ Receptor Localization to Differentially Control TGFβ-Induced Smad Signaling
- (2015) Masahiro Narimatsu et al. DEVELOPMENTAL CELL
- Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap
- (2015) Aleksander D. Szymaniak et al. DEVELOPMENTAL CELL
- Actin remodeling confers BRAF inhibitor resistance to melanoma cells through YAP/TAZ activation
- (2015) M. H. Kim et al. EMBO JOURNAL
- Targeting Hippo pathway by specific interruption of YAP-TEAD interaction using cyclic YAP-like peptides
- (2015) Zheng Zhou et al. FASEB JOURNAL
- β-Catenin destruction complex-independent regulation of Hippo–YAP signaling by APC in intestinal tumorigenesis
- (2015) Jing Cai et al. GENES & DEVELOPMENT
- Adhesion to fibronectin regulates Hippo signaling via the FAK–Src–PI3K pathway
- (2015) Nam-Gyun Kim et al. JOURNAL OF CELL BIOLOGY
- 14-3-3σ Regulates Keratinocyte Proliferation and Differentiation by Modulating Yap1 Cellular Localization
- (2015) Sumitha A.T. Sambandam et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The Hippo Pathway and YAP/TAZ–TEAD Protein–Protein Interaction as Targets for Regenerative Medicine and Cancer Treatment
- (2015) Matteo Santucci et al. JOURNAL OF MEDICINAL CHEMISTRY
- Crosstalk between Hippo and TGFβ: Subcellular Localization of YAP/TAZ/Smad Complexes
- (2015) Karin Grannas et al. JOURNAL OF MOLECULAR BIOLOGY
- YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic Enhancers
- (2015) Giorgio G. Galli et al. MOLECULAR CELL
- A gp130–Src–YAP module links inflammation to epithelial regeneration
- (2015) Koji Taniguchi et al. NATURE
- Inactivation of a Gα s –PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis
- (2015) Ramiro Iglesias-Bartolome et al. NATURE CELL BIOLOGY
- Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway
- (2015) Jung-Soon Mo et al. NATURE CELL BIOLOGY
- Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth
- (2015) Francesca Zanconato et al. NATURE CELL BIOLOGY
- The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies
- (2015) Luping Lin et al. NATURE GENETICS
- Differential regulation of the Hippo pathway by adherens junctions and apical–basal cell polarity modules
- (2015) Chih-Chao Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification and isolation of a dermal lineage with intrinsic fibrogenic potential
- (2015) Y. Rinkevich et al. SCIENCE
- MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway
- (2015) Zhipeng Meng et al. Nature Communications
- Transcriptional Co-repressor Function of the Hippo Pathway Transducers YAP and TAZ
- (2015) Minchul Kim et al. Cell Reports
- YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers
- (2015) Claudia Stein et al. PLoS Genetics
- Elevated YAP and Its Downstream Targets CCN1 and CCN2 in Basal Cell Carcinoma
- (2014) Taihao Quan et al. AMERICAN JOURNAL OF PATHOLOGY
- YAP immunoreactivity is directly related to pilomatrixoma size and proliferation rate
- (2014) Rocco Cappellesso et al. ARCHIVES OF DERMATOLOGICAL RESEARCH
- YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response
- (2014) Luca Azzolin et al. CELL
- Heterogeneity and plasticity of epidermal stem cells
- (2014) T. Schepeler et al. DEVELOPMENT
- The Conserved Misshapen-Warts-Yorkie Pathway Acts in Enteroblasts to Regulate Intestinal Stem Cells in Drosophila
- (2014) Qi Li et al. DEVELOPMENTAL CELL
- Tumour–stroma crosstalk in the development of squamous cell carcinoma
- (2014) Yok Zuan Lim et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Molecular Evolution of the Yap/Yorkie Proto-Oncogene and Elucidation of Its Core Transcriptional Program
- (2014) Aissam Ikmi et al. MOLECULAR BIOLOGY AND EVOLUTION
- Mechanical memory and dosing influence stem cell fate
- (2014) Chun Yang et al. NATURE MATERIALS
- Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation
- (2014) Emanuel Rognoni et al. NATURE MEDICINE
- The Biology of YAP/TAZ: Hippo Signaling and Beyond
- (2014) Stefano Piccolo et al. PHYSIOLOGICAL REVIEWS
- Epidermal Wnt/ -catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors
- (2014) G. Donati et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Yorkie Promotes Transcription by Recruiting a Histone Methyltransferase Complex
- (2014) Hyangyee Oh et al. Cell Reports
- Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin
- (2014) K. Kretzschmar et al. Cold Spring Harbor Perspectives in Medicine
- A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors
- (2013) Mariaceleste Aragona et al. CELL
- Distinct Functions for Wnt/β-Catenin in Hair Follicle Stem Cell Proliferation and Survival and Interfollicular Epidermal Homeostasis
- (2013) Yeon Sook Choi et al. Cell Stem Cell
- Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells
- (2013) D. W. M. Tan et al. DEVELOPMENT
- Intradermal adipocytes mediate fibroblast recruitment during skin wound healing
- (2013) B. A. Schmidt et al. DEVELOPMENT
- CCN2 promotes keratinocyte adhesion and migration via integrin α5β1
- (2013) Elizabeth Kiwanuka et al. EXPERIMENTAL CELL RESEARCH
- YAP and TAZ Regulate Skin Wound Healing
- (2013) Min-Jung Lee et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Pro-Invasive Activity of the Hippo Pathway Effectors YAP and TAZ in Cutaneous Melanoma
- (2013) Flore Nallet-Staub et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Distinct fibroblast lineages determine dermal architecture in skin development and repair
- (2013) Ryan R. Driskell et al. NATURE
- Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
- (2013) Fernando Calvo et al. NATURE CELL BIOLOGY
- Fgf9 from dermal γδ T cells induces hair follicle neogenesis after wounding
- (2013) Denise Gay et al. NATURE MEDICINE
- The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment
- (2013) Randy Johnson et al. NATURE REVIEWS DRUG DISCOVERY
- Lats2 Modulates Adipocyte Proliferation and Differentiation via Hippo Signaling
- (2013) Yang An et al. PLoS One
- Actin-related protein2/3 complex regulates tight junctions and terminal differentiation to promote epidermal barrier formation
- (2013) K. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1
- (2013) R. Fan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interfollicular Epidermal Stem Cells Self-Renew via Autocrine Wnt Signaling
- (2013) X. Lim et al. SCIENCE
- Genome-wide Association of Yorkie with Chromatin and Chromatin-Remodeling Complexes
- (2013) Hyangyee Oh et al. Cell Reports
- Cells of origin and tumor-initiating cells for nonmelanoma skin cancers
- (2012) Khanh Thieu et al. CANCER LETTERS
- Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling
- (2012) Fa-Xing Yu et al. CELL
- β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis
- (2012) Joseph Rosenbluh et al. CELL
- Lineage Tracing
- (2012) Kai Kretzschmar et al. CELL
- Skin-derived multipotent stromal cells – an archrival for mesenchymal stem cells
- (2012) Radhakrishnan Vishnubalaji et al. CELL AND TISSUE RESEARCH
- Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation
- (2012) Naoki Oshimori et al. Cell Stem Cell
- Identification of Serum-Derived Sphingosine-1-Phosphate as a Small Molecule Regulator of YAP
- (2012) Eric Miller et al. CHEMISTRY & BIOLOGY
- Differential response of epithelial stem cell populations in hair follicles to TGF-β signaling
- (2012) Hsien-Yi Lin et al. DEVELOPMENTAL BIOLOGY
- Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
- (2012) B. Zhao et al. GENES & DEVELOPMENT
- Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice
- (2012) Miki Nishio et al. JOURNAL OF CLINICAL INVESTIGATION
- Yap Controls Stem/Progenitor Cell Proliferation in the Mouse Postnatal Epidermis
- (2012) Annemiek Beverdam et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Distinct contribution of stem and progenitor cells to epidermal maintenance
- (2012) Guilhem Mascré et al. NATURE
- Governing epidermal homeostasis by coupling cell-cell adhesion to integrin and growth factor signaling, proliferation, and apoptosis
- (2012) G. Livshits et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain
- (2012) J. M. Lamar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Capturing epidermal stemness for regenerative medicine
- (2012) Yann Barrandon et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Cutting Edge in Medical Management of Cutaneous Oncology
- (2012) Kim Chong et al. SEMINARS IN CUTANEOUS MEDICINE AND SURGERY
- 14-3-3σ and p63 play opposing roles in epidermal tumorigenesis
- (2011) Qiutang Li et al. CARCINOGENESIS
- The Basement Membrane of Hair Follicle Stem Cells Is a Muscle Cell Niche
- (2011) Hironobu Fujiwara et al. CELL
- Dynamics between Stem Cells, Niche, and Progeny in the Hair Follicle
- (2011) Ya-Chieh Hsu et al. CELL
- Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation
- (2011) Karin Schlegelmilch et al. CELL
- Hippo pathway regulation by cell morphology and stress fibers
- (2011) K.-I. Wada et al. DEVELOPMENT
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- Deconstructing the skin: cytoarchitectural determinants of epidermal morphogenesis
- (2011) Cory L. Simpson et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Balancing forces: architectural control of mechanotransduction
- (2011) Christopher C. DuFort et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Wounding mobilizes hair follicle stem cells to form tumors
- (2011) S. Y. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin
- (2011) H. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components
- (2011) N.-G. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- -Catenin Is a Tumor Suppressor That Controls Cell Accumulation by Regulating the Localization and Activity of the Transcriptional Coactivator Yap1
- (2011) M. R. Silvis et al. Science Signaling
- Targeted Therapy in Nonmelanoma Skin Cancers
- (2011) Giulia Spallone et al. Cancers
- Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors
- (2010) Gongping Sun et al. DEVELOPMENTAL BIOLOGY
- Kibra Functions as a Tumor Suppressor Protein that Regulates Hippo Signaling in Conjunction with Merlin and Expanded
- (2010) Jianzhong Yu et al. DEVELOPMENTAL CELL
- The Ordered Architecture of Murine Ear Epidermis Is Maintained by Progenitor Cells with Random Fate
- (2010) David P. Doupé et al. DEVELOPMENTAL CELL
- Unique and redundant functions of integrins in the epidermis
- (2010) Coert Margadant et al. FASEB JOURNAL
- A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF -TRCP
- (2010) B. Zhao et al. GENES & DEVELOPMENT
- The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCFβ-TrCPE3 Ligase
- (2010) Chen-Ying Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila
- (2010) C.-L. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human Skin Aging Is Associated with Reduced Expression of the Stem Cell Markers β1 Integrin and MCSP
- (2009) Adam Giangreco et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Epidermal homeostasis: a balancing act of stem cells in the skin
- (2009) Cédric Blanpain et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- TEAD mediates YAP-dependent gene induction and growth control
- (2008) B. Zhao et al. GENES & DEVELOPMENT
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