Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer

A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer

(2017) Felipe de Sousa e Melo et al.   NATURE

Inflammatory memory sensitizes skin epithelial stem cells to tissue damage

(2017) Shruti Naik et al.   NATURE

Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal

(2017) Kelley S. Yan et al.   NATURE

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo

(2017) Weike Pei et al.   NATURE

Stem cell plasticity enables hair regeneration following Lgr5+ cell loss

(2017) Joerg D. Hoeck et al.   NATURE CELL BIOLOGY

Human haematopoietic stem cell lineage commitment is a continuous process

(2017) Lars Velten et al.   NATURE CELL BIOLOGY

Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF

(2017) Bo O. Zhou et al.   NATURE CELL BIOLOGY

Differential cytokine contributions of perivascular haematopoietic stem cell niches

(2017) Noboru Asada et al.   NATURE CELL BIOLOGY

Acinar cell plasticity and development of pancreatic ductal adenocarcinoma

(2017) Peter Storz   Nature Reviews Gastroenterology & Hepatology

Coupling organelle inheritance with mitosis to balance growth and differentiation

(2017) Amma Asare et al.   SCIENCE

SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 - and RB1 -deficient prostate cancer

(2017) Ping Mu et al.   SCIENCE

Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance

(2017) Sheng Yu Ku et al.   SCIENCE

Transdifferentiation as a Mechanism of Treatment Resistance in a Mouse Model of Castration-Resistant Prostate Cancer

(2017) Min Zou et al.   Cancer Discovery

MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells

(2016) B. N. Sheikh et al.   BLOOD

The bulk of the hematopoietic stem cell population is dispensable for murine steady-state and stress hematopoiesis

(2016) K. B. Schoedel et al.   BLOOD

Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells

(2016) Vionnie W.C. Yu et al.   CELL

Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions

(2016) Jeffrey M. Bernitz et al.   CELL

WNT-SHH Antagonism Specifies and Expands Stem Cells prior to Niche Formation

(2016) Tamara Ouspenskaia et al.   CELL

Leptin Receptor Promotes Adipogenesis and Reduces Osteogenesis by Regulating Mesenchymal Stromal Cells in Adult Bone Marrow

(2016) Rui Yue et al.   Cell Stem Cell

Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters

(2016) Paul W. Tetteh et al.   Cell Stem Cell

Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators

(2016) Lev Silberstein et al.   Cell Stem Cell

BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors

(2016) Tomomi Tadokoro et al.   DEVELOPMENT

Engineered Microenvironments to Direct Epidermal Stem Cell Behavior at Single-Cell Resolution

(2016) Fiona M. Watt   DEVELOPMENTAL CELL

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche

(2016) Henner F. Farin et al.   NATURE

Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development

(2016) Jonathan Henninger et al.   NATURE CELL BIOLOGY

Defining the cellular lineage hierarchy in the interfollicular epidermis of adult skin

(2016) Aiko Sada et al.   NATURE CELL BIOLOGY

Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

(2016) M Ryan Corces et al.   NATURE GENETICS

Leukaemia cell of origin identified by chromatin landscape of bulk tumour cells

(2016) Joshy George et al.   Nature Communications

Single-Cell Transcript Profiles Reveal Multilineage Priming in Early Progenitors Derived from Lgr5 + Intestinal Stem Cells

(2016) Tae-Hee Kim et al.   Cell Reports

Hematopoietic Stem Cell Arrival Triggers Dynamic Remodeling of the Perivascular Niche

(2015) Owen J. Tamplin et al.   CELL

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

(2015) Franziska Paul et al.   CELL

TGF-β Promotes Heterogeneity and Drug Resistance in Squamous Cell Carcinoma

(2015) Naoki Oshimori et al.   CELL

Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions

(2015) Eric M. Pietras et al.   Cell Stem Cell

Switching roles: the functional plasticity of adult tissue stem cells

(2015) A. Wabik et al.   EMBO JOURNAL

A perisinusoidal niche for extramedullary haematopoiesis in the spleen

(2015) Christopher N. Inra et al.   NATURE

Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice

(2015) Rene C. Adam et al.   NATURE

Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal

(2015) Melih Acar et al.   NATURE

Single-cell messenger RNA sequencing reveals rare intestinal cell types

(2015) Dominic Grün et al.   NATURE

Fundamental properties of unperturbed haematopoiesis from stem cells in vivo

(2015) Katrin Busch et al.   NATURE

Distinct routes of lineage development reshape the human blood hierarchy across ontogeny

(2015) F. Notta et al.   SCIENCE

High burden and pervasive positive selection of somatic mutations in normal human skin

(2015) I. Martincorena et al.   SCIENCE

Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tract

(2015) Jason C. Mills et al.   Science Signaling

Integrin-linked kinase regulates the niche of quiescent epidermal stem cells

(2015) Jessica Morgner et al.   Nature Communications

Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tract

(2015) Jason C. Mills et al.   Science Signaling

Transit-Amplifying Cells Orchestrate Stem Cell Activity and Tissue Regeneration

(2014) Ya-Chieh Hsu et al.   CELL

p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer

(2014) Darjus F. Tschaharganeh et al.   CELL

YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response

(2014) Luca Azzolin et al.   CELL

Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow

(2014) Bo O. Zhou et al.   Cell Stem Cell

BMP Signaling and Its pSMAD1/5 Target Genes Differentially Regulate Hair Follicle Stem Cell Lineages

(2014) Maria Genander et al.   Cell Stem Cell

Identification of Regulatory Networks in HSCs and Their Immediate Progeny via Integrated Proteome, Transcriptome, and DNA Methylome Analysis

(2014) Nina Cabezas-Wallscheid et al.   Cell Stem Cell

Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts

(2014) Z. Kabiri et al.   DEVELOPMENT

Polarized Wnt Signaling Regulates Ectodermal Cell Fate in Xenopus

(2014) Ya-Lin Huang et al.   DEVELOPMENTAL CELL

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

(2014) Liran I. Shlush et al.   NATURE

Clonal dynamics of native haematopoiesis

(2014) Jianlong Sun et al.   NATURE

Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging

(2014) Laila Ritsma et al.   NATURE

Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity

(2014) Tae-Hee Kim et al.   NATURE

Genetic and epigenetic fine mapping of causal autoimmune disease variants

(2014) Kyle Kai-How Farh et al.   NATURE

In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators

(2014) Wen-Hui Lien et al.   NATURE CELL BIOLOGY

Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change

(2014) Maria P. Alcolea et al.   NATURE CELL BIOLOGY

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

(2014) Lorenzo Pasquali et al.   NATURE GENETICS

Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells

(2014) Meng Zhao et al.   NATURE MEDICINE

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche

(2014) Hayley Davis et al.   NATURE MEDICINE

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

(2014) Benjamin D Cosgrove et al.   NATURE MEDICINE

Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion

(2014) Ingmar Bruns et al.   NATURE MEDICINE

Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission

(2014) M. R. Corces-Zimmerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatin state dynamics during blood formation

(2014) D. Lara-Astiaso et al.   SCIENCE

 -Catenin Activation Regulates Tissue Growth Non-Cell Autonomously in the Hair Stem Cell Niche

(2014) E. R. Deschene et al.   SCIENCE

Macrophages Contribute to the Cyclic Activation of Adult Hair Follicle Stem Cells

(2014) Donatello Castellana et al.   PLOS BIOLOGY

Wnt Secretion from Epithelial Cells and Subepithelial Myofibroblasts Is Not Required in the Mouse Intestinal Stem Cell Niche In Vivo

(2014) Adrianna K. San Roman et al.   Stem Cell Reports

Clonal Analysis Unveils Self-Renewing Lineage-Restricted Progenitors Generated Directly from Hematopoietic Stem Cells

(2013) Ryo Yamamoto et al.   CELL

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

(2013) Warren A. Whyte et al.   CELL

Super-Enhancers in the Control of Cell Identity and Disease

(2013) Denes Hnisz et al.   CELL

Lessons from the Cancer Genome

(2013) Levi A. Garraway et al.   CELL

Distinct Functions for Wnt/β-Catenin in Hair Follicle Stem Cell Proliferation and Survival and Interfollicular Epidermal Homeostasis

(2013) Yeon Sook Choi et al.   Cell Stem Cell

SLAM Family Markers Resolve Functionally Distinct Subpopulations of Hematopoietic Stem Cells and Multipotent Progenitors

(2013) Hideyuki Oguro et al.   Cell Stem Cell

The Epidermis Comprises Autonomous Compartments Maintained by Distinct Stem Cell Populations

(2013) Mahalia E. Page et al.   Cell Stem Cell

Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration

(2013) Ciara Metcalfe et al.   Cell Stem Cell

Dermal papilla cell number specifies hair size, shape and cycling and its reduction causes follicular decline

(2013) W. Chi et al.   DEVELOPMENT

Intestinal label-retaining cells are secretory precursors expressing Lgr5

(2013) Simon J. A. Buczacki et al.   NATURE

Dedifferentiation of committed epithelial cells into stem cells in vivo

(2013) Purushothama Rao Tata et al.   NATURE

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

(2013) Lei Ding et al.   NATURE

Spatial organization within a niche as a determinant of stem-cell fate

(2013) Panteleimon Rompolas et al.   NATURE

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy

(2013) Alejandra Sanjuan-Pla et al.   NATURE

Arteriolar niches maintain haematopoietic stem cell quiescence

(2013) Yuya Kunisaki et al.   NATURE

Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants

(2013) S. C. J. Parker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nfatc1 orchestrates aging in hair follicle stem cells

(2013) B. E. Keyes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation

(2013) C. Tomasetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic Reprogramming in Cancer

(2013) M. L. Suva et al.   SCIENCE

A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro

(2013) S. J. Habib et al.   SCIENCE

Interfollicular Epidermal Stem Cells Self-Renew via Autocrine Wnt Signaling

(2013) X. Lim et al.   SCIENCE

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

Evidence for a Crucial Role of Paneth Cells in Mediating the Intestinal Response to Injury

(2013) Lee Parry et al.   STEM CELLS

DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus

(2013) Lucas TJ Kaaij et al.   GENOME BIOLOGY

Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair

(2012) Catherine P. Lu et al.   CELL

The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor

(2012) Anne E. Powell et al.   CELL

Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties

(2012) Sarah Schwitalla et al.   CELL

Sox2 in the Dermal Papilla Niche Controls Hair Growth by Fine-Tuning BMP Signaling in Differentiating Hair Shaft Progenitors

(2012) Carlos Clavel et al.   DEVELOPMENTAL CELL

The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers

(2012) Javier Muñoz et al.   EMBO JOURNAL

Shh maintains dermal papilla identity and hair morphogenesis via a Noggin-Shh regulatory loop

(2012) W.-M. Woo et al.   GENES & DEVELOPMENT

Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration

(2012) Peggy S. Myung et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Defining the mode of tumour growth by clonal analysis

(2012) Gregory Driessens et al.   NATURE

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

(2012) Huai-Xiang Hao et al.   NATURE

mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake

(2012) Ömer H. Yilmaz et al.   NATURE

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

Dll1+ secretory progenitor cells revert to stem cells upon crypt damage

(2012) Johan H. van Es et al.   NATURE CELL BIOLOGY

Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow

(2012) Aya Ludin et al.   NATURE IMMUNOLOGY

Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1)

(2012) A. Durand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

(2012) M. T. Maurano et al.   SCIENCE

Clonal Evolution of Preleukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia

(2012) M. Jan et al.   Science Translational Medicine

Coexpression of Normally Incompatible Developmental Pathways in Retinoblastoma Genesis

(2011) Justina McEvoy et al.   CANCER CELL

Basal Cell Carcinomas Arise from Hair Follicle Stem Cells in Ptch1+/− Mice

(2011) Grace Ying Wang et al.   CANCER CELL

Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling

(2011) Eric Festa et al.   CELL

Lineage Regulators Direct BMP and Wnt Pathways to Cell-Specific Programs during Differentiation and Regeneration

(2011) Eirini Trompouki et al.   CELL

Dynamics between Stem Cells, Niche, and Progeny in the Hair Follicle

(2011) Ya-Chieh Hsu et al.   CELL

Wnt Regulates Spindle Asymmetry to Generate Asymmetric Nuclear β-Catenin in C. elegans

(2011) Kenji Sugioka et al.   CELL

The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons

(2011) Lishi Li et al.   CELL

Genome-wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage

(2011) Wen-Hui Lien et al.   Cell Stem Cell

Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells

(2011) Shintaro Tanimura et al.   Cell Stem Cell

Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells

(2011) Isaac Brownell et al.   Cell Stem Cell

Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo

(2011) Roxana C Mustata et al.   EMBO REPORTS

Dll1- and Dll4-Mediated Notch Signaling Are Required for Homeostasis of Intestinal Stem Cells

(2011) Luca Pellegrinet et al.   GASTROENTEROLOGY

Bone marrow CD169+macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

(2011) Andrew Chow et al.   JOURNAL OF EXPERIMENTAL MEDICINE

In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche

(2011) Joji Fujisaki et al.   NATURE

A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable

(2011) Hua Tian et al.   NATURE

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

(2011) Wim de Lau et al.   NATURE

Distinct stem cells contribute to mammary gland development and maintenance

(2011) Alexandra Van Keymeulen et al.   NATURE

Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding

(2011) Rong Lu et al.   NATURE BIOTECHNOLOGY

Dnmt3a is essential for hematopoietic stem cell differentiation

(2011) Grant A Challen et al.   NATURE GENETICS

Identifying the cellular origin of squamous skin tumors

(2011) G. Lapouge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-  and integrin/focal adhesion kinase (FAK) signaling

(2011) M. Schober et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defining the origins of Ras/p53-mediated squamous cell carcinoma

(2011) A. C. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations

(2011) K. S. Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interconversion Between Intestinal Stem Cell Populations in Distinct Niches

(2011) N. Takeda et al.   SCIENCE

Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells

(2011) M. V. Plikus et al.   SCIENCE

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

(2010) I. G. Winkler et al.   BLOOD

Phenotypic Heterogeneity among Tumorigenic Melanoma Cells from Patients that Is Reversible and Not Hierarchically Organized

(2010) Elsa Quintana et al.   CANCER CELL

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

Primary Tumor Genotype Is an Important Determinant in Identification of Lung Cancer Propagating Cells

(2010) Stephen J. Curtis et al.   Cell Stem Cell

BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells

(2010) Gemma Molyneux et al.   Cell Stem Cell

The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche

(2010) Yoshiki Omatsu et al.   IMMUNITY

Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment

(2010) Yohei Morita et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mixed-phenotype acute leukemia: historical overview and a new definition

(2010) O K Weinberg et al.   LEUKEMIA

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

(2010) Jason R. Spence et al.   NATURE

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

Identification of the cell lineage at the origin of basal cell carcinoma

(2010) Khalil Kass Youssef et al.   NATURE CELL BIOLOGY

Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells

(2010) Hideki Kobayashi et al.   NATURE CELL BIOLOGY

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

(2010) I. Beerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells

(2010) R. K. Montgomery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin

(2010) H. J. Snippert et al.   SCIENCE

The Wnt/ -Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML

(2010) Y. Wang et al.   SCIENCE

Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift

(2010) C. Lopez-Garcia et al.   SCIENCE

Regeneration of intestinal stem/progenitor cells following doxorubicin treatment of mice

(2009) Christopher M. Dekaney et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A Two-Step Mechanism for Stem Cell Activation during Hair Regeneration

(2009) Valentina Greco et al.   Cell Stem Cell

Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis

(2009) Kim B. Jensen et al.   Cell Stem Cell

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

IFNα activates dormant haematopoietic stem cells in vivo

(2009) Marieke A. G. Essers et al.   NATURE

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells

(2008) Valerie Horsley et al.   CELL

Ontogeny and Multipotency of Neural Crest-Derived Stem Cells in Mouse Bone Marrow, Dorsal Root Ganglia, and Whisker Pad

(2008) Narihito Nagoshi et al.   Cell Stem Cell

Mobilized Hematopoietic Stem Cell Yield Depends on Species-Specific Circadian Timing

(2008) Daniel Lucas et al.   Cell Stem Cell

Quantitative proliferation dynamics and random chromosome segregation of hair follicle stem cells

(2008) Sanjeev K Waghmare et al.   EMBO JOURNAL

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

(2008) Cristina Lo Celso et al.   NATURE

Detection of functional haematopoietic stem cell niche using real-time imaging

(2008) Yucai Xie et al.   NATURE

Crypt stem cells as the cells-of-origin of intestinal cancer

(2008) Nick Barker et al.   NATURE

Haematopoietic stem cell release is regulated by circadian oscillations

(2008) Simón Méndez-Ferrer et al.   NATURE

Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration

(2008) Maksim V. Plikus et al.   NATURE

Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells

(2008) Adlen Foudi et al.   NATURE BIOTECHNOLOGY

Lgr5 marks cycling, yet long-lived, hair follicle stem cells

(2008) Viljar Jaks et al.   NATURE GENETICS

Bmi1 is expressed in vivo in intestinal stem cells

(2008) Eugenio Sangiorgi et al.   NATURE GENETICS

Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

(2008) Keith W. Orford et al.   NATURE REVIEWS GENETICS