Targeting the Hippo Pathway and Cancer through the TEAD Family of Transcription Factors
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting the Hippo Pathway and Cancer through the TEAD Family of Transcription Factors
Authors
Keywords
-
Journal
Cancers
Volume 10, Issue 3, Pages 81
Publisher
MDPI AG
Online
2018-03-20
DOI
10.3390/cancers10030081
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- 1H, 13C, 15N resonance assignment of human YAP 50–171 fragment
- (2018) Michael Feichtinger et al. Biomolecular NMR Assignments
- Targeting Transcriptional Enhanced Associate Domains (TEADs)
- (2017) Floriane Gibault et al. JOURNAL OF MEDICINAL CHEMISTRY
- DNAproDB: an interactive tool for structural analysis of DNA–protein complexes
- (2017) Jared M. Sagendorf et al. NUCLEIC ACIDS RESEARCH
- DNA-binding mechanism of the Hippo pathway transcription factor TEAD4
- (2017) Z Shi et al. ONCOGENE
- Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches
- (2017) Hung Yi Kristal Kaan et al. PLoS One
- Effect of the acylation of TEAD4 on its interaction with co-activators YAP and TAZ
- (2017) Yannick Mesrouze et al. PROTEIN SCIENCE
- Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
- (2017) Zachary R. Crook et al. Nature Communications
- Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex
- (2017) Hung Yi Kristal Kaan et al. Scientific Reports
- TEAD1 enhances proliferation via activating SP1 in colorectal cancer
- (2016) Min-Hao Yu et al. BIOMEDICINE & PHARMACOTHERAPY
- A Potential Structural Switch for Regulating DNA-Binding by TEAD Transcription Factors
- (2016) Dong-Sun Lee et al. JOURNAL OF MOLECULAR BIOLOGY
- Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway
- (2016) PuiYee Chan et al. Nature Chemical Biology
- Palmitoylation of TEAD Transcription Factors Is Required for Their Stability and Function in Hippo Pathway Signaling
- (2016) Cameron L. Noland et al. STRUCTURE
- A splicing isoform of TEAD4 attenuates the Hippo–YAP signalling to inhibit tumour proliferation
- (2016) Yangfan Qi et al. Nature Communications
- Targeting Hippo pathway by specific interruption of YAP-TEAD interaction using cyclic YAP-like peptides
- (2015) Zheng Zhou et al. FASEB JOURNAL
- YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic Enhancers
- (2015) Giorgio G. Galli et al. MOLECULAR CELL
- Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth
- (2015) Francesca Zanconato et al. NATURE CELL BIOLOGY
- Increased TEAD4 expression and nuclear localization in colorectal cancer promote epithelial–mesenchymal transition and metastasis in a YAP-independent manner
- (2015) Y Liu et al. ONCOGENE
- Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy
- (2015) Ajaybabu V. Pobbati et al. STRUCTURE
- Effects of the Hippo Signaling Pathway in Human Gastric Cancer
- (2014) Guang-Xi Zhou et al. Asian Pacific Journal of Cancer Prevention
- The PDZ-binding motif of Yes-associated protein is required for its co-activation of TEAD-mediated CTGF transcription and oncogenic cell transforming activity
- (2014) Tadanori Shimomura et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer
- (2014) Shi Jiao et al. CANCER CELL
- Activation of endocrine-related gene expression in placental choriocarcinoma cell lines following DNA methylation knock-down
- (2014) K. Hogg et al. MOLECULAR HUMAN REPRODUCTION
- Emerging roles of TEAD transcription factors and its coactivators in cancers
- (2013) Ajaybabu V. Pobbati et al. CANCER BIOLOGY & THERAPY
- Integrative genomics analysis reveals the multilevel dysregulation and oncogenic characteristics of TEAD4 in gastric cancer
- (2013) Byungho Lim et al. CARCINOGENESIS
- Spatial Organization of Hippo Signaling at the Plasma Membrane Mediated by the Tumor Suppressor Merlin/NF2
- (2013) Feng Yin et al. CELL
- Genome-wide Association of Yorkie with Chromatin and Chromatin-Remodeling Complexes
- (2013) Hyangyee Oh et al. Cell Reports
- Identification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 gene
- (2012) Christian J. Gaffney et al. GENE
- Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
- (2012) Y. Liu-Chittenden et al. GENES & DEVELOPMENT
- Unbiased Discovery of Interactions at a Control Locus Driving Expression of the Cancer-Specific Therapeutic and Diagnostic Target, Mesothelin
- (2012) Yunzhao R. Ren et al. JOURNAL OF PROTEOME RESEARCH
- The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain
- (2012) J. M. Lamar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural and Functional Similarity between the Vgll1-TEAD and the YAP-TEAD Complexes
- (2012) Ajaybabu V. Pobbati et al. STRUCTURE
- Structural Features and Ligand Binding Properties of Tandem WW Domains from YAP and TAZ, Nuclear Effectors of the Hippo Pathway
- (2011) Claire Webb et al. BIOCHEMISTRY
- Transcription factor TEAD4 regulates expression of Myogenin and the unfolded protein response genes during C2C12 cell differentiation
- (2011) A Benhaddou et al. CELL DEATH AND DIFFERENTIATION
- Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
- (2011) F. Sievers et al. Molecular Systems Biology
- Targeting protein–protein interactions for therapeutic intervention: a challenge for the future
- (2010) Giovanna Zinzalla et al. Future Medicinal Chemistry
- Structural basis of YAP recognition by TEAD4 in the Hippo pathway
- (2010) L. Chen et al. GENES & DEVELOPMENT
- Structural insights into the YAP and TEAD complex
- (2010) Z. Li et al. GENES & DEVELOPMENT
- A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF -TRCP
- (2010) B. Zhao et al. GENES & DEVELOPMENT
- The chemical toolbox for monitoring protein fatty acylation and prenylation
- (2010) Rami N Hannoush et al. Nature Chemical Biology
- AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma
- (2010) M Z Xu et al. ONCOGENE
- Structural and functional analysis of the YAP-binding domain of human TEAD2
- (2010) W. Tian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma
- (2009) Michelle Z. Xu et al. CANCER
- TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer
- (2008) J F Knight et al. BRITISH JOURNAL OF CANCER
- A Role for TAZ in Migration, Invasion, and Tumorigenesis of Breast Cancer Cells
- (2008) S. W. Chan et al. CANCER RESEARCH
- Negative Regulation of YAP by LATS1 Underscores Evolutionary Conservation of the Drosophila Hippo Pathway
- (2008) J. Zhang et al. CANCER RESEARCH
- TEAD mediates YAP-dependent gene induction and growth control
- (2008) B. Zhao et al. GENES & DEVELOPMENT
- Redundant Roles of Tead1 and Tead2 in Notochord Development and the Regulation of Cell Proliferation and Survival
- (2008) A. Sawada et al. MOLECULAR AND CELLULAR BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More