Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis
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Title
Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis
Authors
Keywords
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Journal
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Volume 308, Issue 4, Pages L344-L357
Publisher
American Physiological Society
Online
2014-12-13
DOI
10.1152/ajplung.00300.2014
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Note: Only part of the references are listed.- Targeting Interleukin-13 with Tralokinumab Attenuates Lung Fibrosis and Epithelial Damage in a Humanized SCID Idiopathic Pulmonary Fibrosis Model
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- (2014) Chun Yang et al. NATURE MATERIALS
- A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors
- (2013) Mariaceleste Aragona et al. CELL
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- (2013) Paul A. Janmey et al. DIFFERENTIATION
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- (2013) Laura A. Johnson et al. INFLAMMATORY BOWEL DISEASES
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- (2013) Yong Zhou et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2013) Fernando Calvo et al. NATURE CELL BIOLOGY
- Therapy for Fibrotic Diseases: Nearing the Starting Line
- (2013) S. L. Friedman et al. Science Translational Medicine
- Improved throughput traction microscopy reveals pivotal role for matrix stiffness in fibroblast contractility and TGF-β responsiveness
- (2012) Aleksandar Marinković et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Acellular Normal and Fibrotic Human Lung Matrices as a Culture System forIn VitroInvestigation
- (2012) Adam J. Booth et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Matrix Stiffness–Induced Myofibroblast Differentiation Is Mediated by Intrinsic Mechanotransduction
- (2012) Xiangwei Huang et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Matrices of Physiologic Stiffness Potently Inactivate Idiopathic Pulmonary Fibrosis Fibroblasts
- (2012) Aleksandar Marinković et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling
- (2012) Fa-Xing Yu et al. CELL
- The mechanical memory of lung myofibroblasts
- (2012) Jenna L. Balestrini et al. Integrative Biology
- Pulmonary fibrosis: patterns and perpetrators
- (2012) Paul W. Noble et al. JOURNAL OF CLINICAL INVESTIGATION
- Physical and chemical microenvironmental cues orthogonally control the degree and duration of fibrosis-associated epithelial-to-mesenchymal transitions
- (2012) Ashley C Brown et al. JOURNAL OF PATHOLOGY
- Mechanisms of fibrosis: therapeutic translation for fibrotic disease
- (2012) Thomas A Wynn et al. NATURE MEDICINE
- Therapeutic Value of Small Molecule Inhibitor to Plasminogen Activator Inhibitor–1 for Lung Fibrosis
- (2011) Wen-Tan Huang et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Hippo pathway regulation by cell morphology and stress fibers
- (2011) K.-I. Wada et al. DEVELOPMENT
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- (2011) Asish K. Ghosh et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44
- (2011) Yuejuan Li et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2011) Sirio Dupont et al. NATURE
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- (2011) Joon-Il Jun et al. NATURE REVIEWS DRUG DISCOVERY
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- (2011) A Mauviel et al. ONCOGENE
- A Multiwell Platform for Studying Stiffness-Dependent Cell Biology
- (2011) Justin D. Mih et al. PLoS One
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- (2010) Steven K. Huang et al. AMERICAN JOURNAL OF PATHOLOGY
- The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version
- (2010) B. Zhao et al. GENES & DEVELOPMENT
- Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression
- (2010) Fei Liu et al. JOURNAL OF CELL BIOLOGY
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- (2010) Bin Zhao et al. JOURNAL OF CELL SCIENCE
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- (2010) Vivian Barry-Hamilton et al. NATURE MEDICINE
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- (2010) G. Trujillo et al. Science Translational Medicine
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