Mitofusins: Disease Gatekeepers and Hubs in Mitochondrial Quality Control by E3 Ligases
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Title
Mitofusins: Disease Gatekeepers and Hubs in Mitochondrial Quality Control by E3 Ligases
Authors
Keywords
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Journal
Frontiers in Physiology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-05-09
DOI
10.3389/fphys.2019.00517
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Note: Only part of the references are listed.- ER-mitochondria interactions: Both strength and weakness within cancer cells
- (2019) Mabrouka Doghman-Bouguerra et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- MFN2 mutations in Charcot-Marie-Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics
- (2019) Delfina Larrea et al. HUMAN MOLECULAR GENETICS
- Mitochondrial proteins: from biogenesis to functional networks
- (2019) Nikolaus Pfanner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Altered interplay between endoplasmic reticulum and mitochondria in Charcot–Marie–Tooth type 2A neuropathy
- (2019) Nathalie Bernard-Marissal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Breaking the chains: deubiquitylating enzyme specificity begets function
- (2019) Michael J. Clague et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
- (2019) Evandro F. Fang et al. NATURE NEUROSCIENCE
- Disease Modeling and Therapeutic Strategies in CMT2A: State of the Art
- (2019) Kordelia Barbullushi et al. MOLECULAR NEUROBIOLOGY
- Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model
- (2019) Yueqin Zhou et al. JOURNAL OF CLINICAL INVESTIGATION
- BNIP3L/NIX and FUNDC1-mediated mitophagy is required for mitochondrial network remodeling during cardiac progenitor cell differentiation
- (2019) Mark A. Lampert et al. Autophagy
- Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers
- (2018) Sung Kook Chun et al. AGING CELL
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Mitofusin 2 Exerts a Protective Role in Ischemia Reperfusion Injury Through Increasing Autophagy
- (2018) Cheng Peng et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance
- (2018) Sarah Pickles et al. CURRENT BIOLOGY
- Interacting organelles
- (2018) Sarah Cohen et al. CURRENT OPINION IN CELL BIOLOGY
- Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER
- (2018) Jonathan R. Friedman et al. DEVELOPMENTAL CELL
- Mitofusin gain and loss of function drive pathogenesis in Drosophila models of CMT2A neuropathy
- (2018) Najla El Fissi et al. EMBO REPORTS
- Mitochondrial dynamics: overview of molecular mechanisms
- (2018) Lisa Tilokani et al. Essays in Biochemistry
- Iron–sulfur clusters: from metals through mitochondria biogenesis to disease
- (2018) Mauricio Cardenas-Rodriguez et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Building and decoding ubiquitin chains for mitophagy
- (2018) J. Wade Harper et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- RBR ligase–mediated ubiquitin transfer: a tale with many twists and turns
- (2018) Helen Walden et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RBR ligase–mediated ubiquitin transfer: a tale with many twists and turns
- (2018) Helen Walden et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cdc48 regulates a deubiquitylase cascade critical for mitochondrial fusion
- (2018) Tânia Simões et al. eLife
- Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy
- (2018) Gian-Luca McLelland et al. eLife
- Ambiguous Effects of Autophagy Activation Following Hypoperfusion/Ischemia
- (2018) Michela Ferrucci et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Regulation of Endoplasmic Reticulum-Mitochondria contacts by Parkin via Mfn2
- (2018) Valentina Basso et al. PHARMACOLOGICAL RESEARCH
- Here, there, and everywhere: The importance of ER membrane contact sites
- (2018) Haoxi Wu et al. SCIENCE
- SUMO-mediated regulation of NLRP3 modulates inflammasome activity
- (2018) Rachael Barry et al. Nature Communications
- HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα
- (2018) Anthea Di Rita et al. Nature Communications
- Mitochondrial quality control as a key determinant of cell survival
- (2018) Lucia Sedlackova et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mitochondrial network structure homeostasis and cell death
- (2018) Long-long Xie et al. CANCER SCIENCE
- An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia
- (2018) Toshiro Saito et al. JOURNAL OF CLINICAL INVESTIGATION
- Ubiquitin-dependent protein degradation at the endoplasmic reticulum and nuclear envelope
- (2018) Adrian B. Mehrtash et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Phosphorylation of Parkin at serine 65 is essential for its activation in vivo
- (2018) Thomas G. McWilliams et al. Open Biology
- Iron–sulfur cluster biogenesis and trafficking in mitochondria
- (2017) Joseph J. Braymer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A new mitofusin topology places the redox-regulated C terminus in the mitochondrial intermembrane space
- (2017) Sevan Mattie et al. JOURNAL OF CELL BIOLOGY
- Frequent genes in rare diseases: panel-based next generation sequencing to disclose causal mutations in hereditary neuropathies
- (2017) Maike F. Dohrn et al. JOURNAL OF NEUROCHEMISTRY
- Mitofusin 2 Promotes Apoptosis of CD4+ T Cells by Inhibiting Autophagy in Sepsis
- (2017) Lan Ying et al. MEDIATORS OF INFLAMMATION
- Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling
- (2017) Martin A. Michel et al. MOLECULAR CELL
- MFN1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion
- (2017) Yu-Lu Cao et al. NATURE
- Ubiquitylation at the crossroads of development and disease
- (2017) Michael Rape NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Parkin–phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity
- (2017) Atul Kumar et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Apoptotic foci at mitochondria: in and around Bax pores
- (2017) Begoña Ugarte-Uribe et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy
- (2017) Yong Tae Kwon et al. TRENDS IN BIOCHEMICAL SCIENCES
- Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms
- (2017) Jesse S. Kerr et al. TRENDS IN NEUROSCIENCES
- Gp78 E3 Ubiquitin Ligase: Essential Functions and Contributions in Proteostasis
- (2017) Vibhuti Joshi et al. Frontiers in Cellular Neuroscience
- Parkin–phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity
- (2017) Atul Kumar et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity
- (2017) Karine Doiron et al. Scientific Reports
- Control of mitochondrial biogenesis and function by the ubiquitin–proteasome system
- (2017) Piotr Bragoszewski et al. Open Biology
- Valosin-containing protein (VCP/p97) inhibitors relieve Mitofusin-dependent mitochondrial defects due to VCP disease mutants
- (2017) Ting Zhang et al. eLife
- PINK1/Parkin-Dependent Mitochondrial Surveillance: From Pleiotropy to Parkinson's Disease
- (2017) Francois Mouton-Liger et al. Frontiers in Molecular Neuroscience
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- (2017) Galdo Bustos et al. Frontiers in Oncology
- The Effect of a Novel c.820C>T (Arg274Trp) Mutation in the Mitofusin 2 Gene on Fibroblast Metabolism and Clinical Manifestation in a Patient
- (2017) Małgorzata Beręsewicz et al. PLoS One
- Mitochondrial dynamics during cell cycling
- (2016) Rostyslav Horbay et al. APOPTOSIS
- Endoplasmic reticulum-mitochondrial interaction mediated by mitofusin-1 or mitofusin-2 is not required for lipid droplet formation or adipocyte differentiation
- (2016) Pamela J. McFie et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Regulation of Mitofusin1 by Mahogunin Ring Finger-1 and the proteasome modulates mitochondrial fusion
- (2016) Rukmini Mukherjee et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Ubiquitin modifications
- (2016) Kirby N Swatek et al. CELL RESEARCH
- Mfn2 deficiency links age‐related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway
- (2016) David Sebastián et al. EMBO JOURNAL
- Selective mitochondrial depletion, apoptosis resistance, and increased mitophagy in human Charcot-Marie-Tooth 2A motor neurons
- (2016) Federica Rizzo et al. HUMAN MOLECULAR GENETICS
- Structures of human mitofusin 1 provide insight into mitochondrial tethering
- (2016) Yuanbo Qi et al. JOURNAL OF CELL BIOLOGY
- Metabolic regulation of mitochondrial dynamics
- (2016) Prashant Mishra et al. JOURNAL OF CELL BIOLOGY
- Ubiquitin-mediated regulation of the E3 ligase GP78 by MGRN1 in trans affects mitochondrial homeostasis
- (2016) Rukmini Mukherjee et al. JOURNAL OF CELL SCIENCE
- OPA1 processing in cell death and disease – the long and short of it
- (2016) Thomas MacVicar et al. JOURNAL OF CELL SCIENCE
- Mitofusin-2 knockdown increases ER-mitochondria contact and decreases amyloid β-peptide production
- (2016) Nuno Santos Leal et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Increased mitochondrial fusion in a autosomal recessive CMT2A family with mitochondrial GTPase mitofusin 2 mutations
- (2016) Philippe Codron et al. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM
- Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein
- (2016) Shan Xu et al. MOLECULAR BIOLOGY OF THE CELL
- Mitofusins, from Mitochondria to Metabolism
- (2016) Emilie Schrepfer et al. MOLECULAR CELL
- The increasing complexity of the ubiquitin code
- (2016) Richard Yau et al. NATURE CELL BIOLOGY
- Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether
- (2016) Deborah Naon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hereditary neuropathies: An update
- (2016) T. Stojkovic REVUE NEUROLOGIQUE
- Tributyltin induces mitochondrial fission through Mfn1 degradation in human induced pluripotent stem cells
- (2016) Shigeru Yamada et al. TOXICOLOGY IN VITRO
- Ubiquitin-Dependent And Independent Signals In Selective Autophagy
- (2016) Aliaksandr Khaminets et al. TRENDS IN CELL BIOLOGY
- A phospholipid transfer function of ER-mitochondria encounter structure revealed in vitro
- (2016) Rieko Kojima et al. Scientific Reports
- BCL2L13 is a mammalian homolog of the yeast mitophagy receptor Atg32
- (2015) Kinya Otsu et al. Autophagy
- HDAC6 maintains mitochondrial connectivity under hypoxic stress by suppressing MARCH5/MITOL dependent MFN2 degradation
- (2015) Hak-June Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mitochondrial Fission and Fusion Factors Reciprocally Orchestrate Mitophagic Culling in Mouse Hearts and Cultured Fibroblasts
- (2015) Moshi Song et al. Cell Metabolism
- Fatty Acid Trafficking in Starved Cells: Regulation by Lipid Droplet Lipolysis, Autophagy, and Mitochondrial Fusion Dynamics
- (2015) Angelika S. Rambold et al. DEVELOPMENTAL CELL
- Expanding the ubiquitin code through post-translational modification
- (2015) L. Herhaus et al. EMBO REPORTS
- Axonal Charcot–Marie–Tooth disease patient-derived motor neurons demonstrate disease-specific phenotypes including abnormal electrophysiological properties
- (2015) Mario A. Saporta et al. EXPERIMENTAL NEUROLOGY
- Parkin structure and function
- (2015) Marjan Seirafi et al. FEBS Journal
- Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels
- (2015) Arnaud Mourier et al. JOURNAL OF CELL BIOLOGY
- Distinct mechanisms controlling rough and smooth endoplasmic reticulum contacts with mitochondria
- (2015) P. T. C. Wang et al. JOURNAL OF CELL SCIENCE
- Loss of mitofusin 2 links beta-amyloid-mediated mitochondrial fragmentation and Cdk5-induced oxidative stress in neuron cells
- (2015) Junghyung Park et al. JOURNAL OF NEUROCHEMISTRY
- MFN2-related neuropathies: Clinical features, molecular pathogenesis and therapeutic perspectives
- (2015) Giulia Stuppia et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- MAPL SUMOylation of Drp1 Stabilizes an ER/Mitochondrial Platform Required for Cell Death
- (2015) Julien Prudent et al. MOLECULAR CELL
- Mahogunin Ring Finger-1 (MGRN1), a Multifaceted Ubiquitin Ligase: Recent Unraveling of Neurobiological Mechanisms
- (2015) Arun Upadhyay et al. MOLECULAR NEUROBIOLOGY
- Mechanism of phospho-ubiquitin-induced PARKIN activation
- (2015) Tobias Wauer et al. NATURE
- The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
- (2015) Michael Lazarou et al. NATURE
- USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria
- (2015) Christian N. Cunningham et al. NATURE CELL BIOLOGY
- Mitofusin 2 ablation increases endoplasmic reticulum–mitochondria coupling
- (2015) Riccardo Filadi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice
- (2015) G. Gong et al. SCIENCE
- VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function
- (2015) Fu-Lei Tang et al. Cell Reports
- Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
- (2014) Agne Kazlauskaite et al. BIOCHEMICAL JOURNAL
- Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy
- (2014) Lucia Cilenti et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Enhanced Protein Degradation by Branched Ubiquitin Chains
- (2014) Hermann-Josef Meyer et al. CELL
- AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1
- (2014) F Strappazzon et al. CELL DEATH AND DIFFERENTIATION
- A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30
- (2014) Wen Yue et al. CELL RESEARCH
- A new pathway for mitochondrial quality control: mitochondrial-derived vesicles
- (2014) A. Sugiura et al. EMBO JOURNAL
- RBR E3-ligases at work
- (2014) J. J. Smit et al. EMBO REPORTS
- Dynamic survey of mitochondria by ubiquitin
- (2014) M. Escobar-Henriques et al. EMBO REPORTS
- ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy
- (2014) W. Wu et al. EMBO REPORTS
- Mitofusin 1 degradation is induced by a disruptor of mitochondrial calcium homeostasis, CGP37157: A role in apoptosis in prostate cancer cells
- (2014) VIVEK CHOUDHARY et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
- (2014) Lesley A. Kane et al. JOURNAL OF CELL BIOLOGY
- MFN1 deacetylation activates adaptive mitochondrial fusion and protects metabolically challenged mitochondria
- (2014) J.-Y. Lee et al. JOURNAL OF CELL SCIENCE
- Hereditary motor and sensory neuropathies or Charcot–Marie–Tooth diseases: An update
- (2014) Meriem Tazir et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Distribution and Apoptotic Function of Outer Membrane Proteins Depend on Mitochondrial Fusion
- (2014) David Weaver et al. MOLECULAR CELL
- Ubiquitin is phosphorylated by PINK1 to activate parkin
- (2014) Fumika Koyano et al. NATURE
- Mitochondrial form and function
- (2014) Jonathan R. Friedman et al. NATURE
- The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy
- (2014) Baris Bingol et al. NATURE
- Parkin and PINK1: much more than mitophagy
- (2014) Leslie A. Scarffe et al. TRENDS IN NEUROSCIENCES
- MARCH5-mediated quality control on acetylated Mfn1 facilitates mitochondrial homeostasis and cell survival
- (2014) Y-Y Park et al. Cell Death & Disease
- Phosphorylation by PINK1 Releases the UBL Domain and Initializes the Conformational Opening of the E3 Ubiquitin Ligase Parkin
- (2014) Thomas R. Caulfield et al. PLoS Computational Biology
- Charcot-Marie-Tooth Disease: An Overview of Genotypes, Phenotypes, and Clinical Management Strategies
- (2014) Rima El-Abassi et al. PM&R
- Mitochondria-mediated apoptosis in mammals
- (2014) Shunbin Xiong et al. Protein & Cell
- Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production
- (2014) Hector Sandoval et al. eLife
- A form of mitofusin 2 (Mfn2) lacking the transmembrane domains and the COOH-terminal end stimulates metabolism in muscle and liver cells
- (2013) Jessica Segalés et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation
- (2013) Kasturi Mitra BIOESSAYS
- Mitochondrial fusion and fission proteins: novel therapeutic targets for combating cardiovascular disease
- (2013) A R Hall et al. BRITISH JOURNAL OF PHARMACOLOGY
- Mitofusins: Mighty Regulators of Metabolism
- (2013) Umut Ozcan CELL
- Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance
- (2013) Marc Schneeberger et al. CELL
- Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure
- (2013) Marc Liesa et al. Cell Metabolism
- Structure of the human Parkin ligase domain in an autoinhibited state
- (2013) Tobias Wauer et al. EMBO JOURNAL
- Raft endocytosis of AMF regulates mitochondrial dynamics through Rac1 signaling and the Gp78 ubiquitin ligase
- (2013) J. Shankar et al. JOURNAL OF CELL SCIENCE
- Autosomal recessive Charcot-Marie-Tooth disease: from genes to phenotypes
- (2013) Meriem Tazir et al. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM
- Regulation of mitophagy by the Gp78 E3 ubiquitin ligase
- (2013) Min Fu et al. MOLECULAR BIOLOGY OF THE CELL
- Two Deubiquitylases Act on Mitofusin and Regulate Mitochondrial Fusion along Independent Pathways
- (2013) Fabian Anton et al. MOLECULAR CELL
- MITOL Regulates Endoplasmic Reticulum-Mitochondria Contacts via Mitofusin2
- (2013) Ayumu Sugiura et al. MOLECULAR CELL
- Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
- (2013) Shireen A. Sarraf et al. NATURE
- VCP Is Essential for Mitochondrial Quality Control by PINK1/Parkin and this Function Is Impaired by VCP Mutations
- (2013) Nam Chul Kim et al. NEURON
- Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models
- (2013) L. Hedskog et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria
- (2013) Y. Chen et al. SCIENCE
- A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease
- (2013) Donald E. Spratt et al. Nature Communications
- Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
- (2013) B.E. Riley et al. Nature Communications
- The Ubiquitin Code
- (2012) David Komander et al. Annual Review of Biochemistry
- Depletion of mitochondrial fission factor DRP1 causes increased apoptosis in human colon cancer cells
- (2012) Akane Inoue-Yamauchi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Molecular Mechanisms of Environmental Organotin Toxicity in Mammals
- (2012) Yaichiro Kotake BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Mitochondria: In Sickness and in Health
- (2012) Jodi Nunnari et al. CELL
- Mitofusins 1 and 2 Are Essential for Postnatal Metabolic Remodeling in Heart
- (2012) Kyriakos N. Papanicolaou et al. CIRCULATION RESEARCH
- Central Role of Mitofusin 2 in Autophagosome-Lysosome Fusion in Cardiomyocytes
- (2012) Ting Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Stress-Induced Phosphorylation and Proteasomal Degradation of Mitofusin 2 Facilitates Mitochondrial Fragmentation and Apoptosis
- (2012) Guillaume P. Leboucher et al. MOLECULAR CELL
- Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
- (2012) Lei Liu et al. NATURE CELL BIOLOGY
- Endoplasmic reticulum–mitochondria contacts: function of the junction
- (2012) Ashley A. Rowland et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitofusin-2 Independent Juxtaposition of Endoplasmic Reticulum and Mitochondria: An Ultrastructural Study
- (2012) Pierre Cosson et al. PLoS One
- Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis
- (2012) D. Sebastian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial Fission, Fusion, and Stress
- (2012) R. J. Youle et al. SCIENCE
- Mitofusin 1 is degraded at G2/M phase through ubiquitylation by MARCH5
- (2012) Yong-Yea Park et al. Cell Division
- PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria
- (2012) Kei Okatsu et al. Nature Communications
- PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
- (2012) Kahori Shiba-Fukushima et al. Scientific Reports
- Bnip3 impairs mitochondrial bioenergetics and stimulates mitochondrial turnover
- (2011) S Rikka et al. CELL DEATH AND DIFFERENTIATION
- Mitochondrial Fusion is Essential for Organelle Function and Cardiac Homeostasis
- (2011) Yun Chen et al. CIRCULATION RESEARCH
- Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis
- (2011) Guillaume Pidoux et al. EMBO JOURNAL
- Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
- (2011) Maria Manczak et al. HUMAN MOLECULAR GENETICS
- Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy
- (2011) Nickie C. Chan et al. HUMAN MOLECULAR GENETICS
- Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion
- (2011) F. Anton et al. JOURNAL OF CELL SCIENCE
- Sequential requirements for the GTPase domain of the mitofusin Fzo1 and the ubiquitin ligase SCFMdm30 in mitochondrial outer membrane fusion
- (2011) M. M. Cohen et al. JOURNAL OF CELL SCIENCE
- Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1
- (2011) Liliane Glauser et al. JOURNAL OF NEUROCHEMISTRY
- The Soluble Form of Bax Regulates Mitochondrial Fusion via MFN2 Homotypic Complexes
- (2011) Suzanne Hoppins et al. MOLECULAR CELL
- Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
- (2011) Joshua M. Baughman et al. NATURE
- MFN2 mutations cause severe phenotypes in most patients with CMT2A
- (2011) S. M. E. Feely et al. NEUROLOGY
- What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
- (2011) Olga Corti et al. PHYSIOLOGICAL REVIEWS
- Mutations in PINK1 and Parkin Impair Ubiquitination of Mitofusins in Human Fibroblasts
- (2011) Aleksandar Rakovic et al. PLoS One
- Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation
- (2011) A. S. Rambold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ER Tubules Mark Sites of Mitochondrial Division
- (2011) J. R. Friedman et al. SCIENCE
- Impairing the Mitochondrial Fission and Fusion Balance: A New Mechanism of Neurodegeneration
- (2010) Andrew B. Knott et al. Annals of the New York Academy of Sciences
- p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
- (2010) Derek Narendra et al. Autophagy
- Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization
- (2010) Sylvie Montessuit et al. CELL
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- (2010) Gerald W. Dorn et al. CIRCULATION RESEARCH
- Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
- (2010) Matthew E. Gegg et al. HUMAN MOLECULAR GENETICS
- Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
- (2010) Atsushi Tanaka et al. JOURNAL OF CELL BIOLOGY
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1
- (2010) Y.-Y. Park et al. JOURNAL OF CELL SCIENCE
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- Mitochondrial fusion and fission in cell life and death
- (2010) Benedikt Westermann NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway
- (2010) Angela C. Poole et al. PLoS One
- Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
- (2010) E. Ziviani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- The Role of Mitochondria in Apoptosis
- (2009) Chunxin Wang et al. Annual Review of Genetics
- Structure of a Bacterial Dynamin-like Protein Lipid Tube Provides a Mechanism For Assembly and Membrane Curving
- (2009) Harry H. Low et al. CELL
- Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy
- (2009) Tomotake Kanki et al. DEVELOPMENTAL CELL
- Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy
- (2009) Koji Okamoto et al. DEVELOPMENTAL CELL
- Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
- (2009) Jason L Parsons et al. EMBO JOURNAL
- SLP-2 is required for stress-induced mitochondrial hyperfusion
- (2009) Daniel Tondera et al. EMBO JOURNAL
- MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission
- (2009) Emélie Braschi et al. EMBO REPORTS
- Nix is a selective autophagy receptor for mitochondrial clearance
- (2009) Ivana Novak et al. EMBO REPORTS
- The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice
- (2009) Junko Wakabayashi et al. JOURNAL OF CELL BIOLOGY
- Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
- (2009) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Discovery of Atg5/Atg7-independent alternative macroautophagy
- (2009) Yuya Nishida et al. NATURE
- Adenine nucleotide translocase is involved in a mitochondrial coupling defect in MFN2-related Charcot–Marie–Tooth type 2A disease
- (2009) Virginie Guillet et al. NEUROGENETICS
- PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
- (2009) C. Vives-Bauza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen
- (2009) Benoît Kornmann et al. SCIENCE
- Mitochondrial dynamics as a bridge between mitochondrial dysfunction and insulin resistance
- (2009) Antonio Zorzano et al. ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
- The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development
- (2008) Francesca Bernassola et al. CANCER CELL
- GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth
- (2008) Bicheng Zhang et al. CELL RESEARCH
- Cargo-Selected Transport from the Mitochondria to Peroxisomes Is Mediated by Vesicular Carriers
- (2008) Margaret Neuspiel et al. CURRENT BIOLOGY
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- Mitofusin 2 tethers endoplasmic reticulum to mitochondria
- (2008) Olga Martins de Brito et al. NATURE
- The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein
- (2008) Xudong Zhao et al. NATURE CELL BIOLOGY
- Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase
- (2008) M. Saotome et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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