Cdc48 regulates a deubiquitylase cascade critical for mitochondrial fusion

The deubiquitylating enzyme Ubp12 regulates Rad23-dependent proteasomal degradation

(2017) Daniela Gödderz et al.   JOURNAL OF CELL SCIENCE

Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTs

(2017) Hsuan-Chung Ho et al.   MOLECULAR BIOLOGY OF THE CELL

Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling

(2017) Martin A. Michel et al.   MOLECULAR CELL

An ubiquitin-dependent balance between mitofusin turnover and fatty acids desaturation regulates mitochondrial fusion

(2017) Laetitia Cavellini et al.   Nature Communications

Ubiquitin modifications

(2016) Kirby N Swatek et al.   CELL RESEARCH

VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy

(2016) Chrisovalantis Papadopoulos et al.   EMBO JOURNAL

Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system

(2016) Gian-Luca McLelland et al.   JOURNAL OF CELL BIOLOGY

Doa1 targets ubiquitinated substrates for mitochondria-associated degradation

(2016) Xi Wu et al.   JOURNAL OF CELL BIOLOGY

Fusion of the endoplasmic reticulum by membrane-bound GTPases

(2016) Junjie Hu et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Deubiquitinase activity is required for the proteasomal degradation of misfolded cytosolic proteins upon heat-stress

(2016) Nancy N. Fang et al.   Nature Communications

A mitofusin-dependent docking ring complex triggers mitochondrial fusion in vitro

(2016) Tobias Brandt et al.   eLife

DUBs, the regulation of cell identity and disease: Figure 6

(2015) J. Heideker et al.   BIOCHEMICAL JOURNAL

Ubiquitin-Dependent Lysosomal Membrane Protein Sorting and Degradation

(2015) Ming Li et al.   MOLECULAR CELL

Deubiquitinase-based analysis of ubiquitin chain architecture using Ubiquitin Chain Restriction (UbiCRest)

(2015) Manuela K Hospenthal et al.   Nature Protocols

K63 polyubiquitination is a new modulator of the oxidative stress response

(2015) Gustavo M Silva et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

(2015) Alicia M. Pickrell et al.   NEURON

Layers of DUB regulation

(2015) Danny D. Sahtoe et al.   TRENDS IN BIOCHEMICAL SCIENCES

Clipping or Extracting: Two Ways to Membrane Protein Degradation

(2015) Dönem Avci et al.   TRENDS IN CELL BIOLOGY

K63 polyubiquitination is a new modulator of the oxidative stress response

(2015) Gustavo M Silva et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of the Deubiquitylating Enzyme DmUsp5 in Coupling Ubiquitin Equilibrium to Development and Apoptosis in Drosophila melanogaster

(2015) Levente Kovács et al.   PLoS One

Cellular ubiquitin pool dynamics and homeostasis

(2014) Chul-Woo Park et al.   BMB Reports

Ubiquitin-dependent protein degradation at the yeast endoplasmic reticulum and nuclear envelope

(2014) Dimitrios Zattas et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

A new pathway for mitochondrial quality control: mitochondrial-derived vesicles

(2014) A. Sugiura et al.   EMBO JOURNAL

Dynamic survey of mitochondria by ubiquitin

(2014) M. Escobar-Henriques et al.   EMBO REPORTS

The VCP/p97 system at a glance: connecting cellular function to disease pathogenesis

(2014) H. Meyer et al.   JOURNAL OF CELL SCIENCE

Create and preserve: Proteostasis in development and aging is governed by Cdc48/p97/VCP

(2013) André Franz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Two Deubiquitylases Act on Mitofusin and Regulate Mitochondrial Fusion along Independent Pathways

(2013) Fabian Anton et al.   MOLECULAR CELL

Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation

(2013) Danielle L Swaney et al.   NATURE METHODS

Roles of Mitochondrial Dynamics under Stressful and Normal Conditions in Yeast Cells

(2013) Dmitry A. Knorre et al.   Oxidative Medicine and Cellular Longevity

Deubiquitylases From Genes to Organism

(2013) Michael J. Clague et al.   PHYSIOLOGICAL REVIEWS

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Mechanistic perspective of mitochondrial fusion: Tubulation vs. fragmentation

(2012) Mafalda Escobar-Henriques et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cdc48p/p97-mediated regulation of mitochondrial morphology is Vms1p-independent

(2012) Masatoshi Esaki et al.   JOURNAL OF STRUCTURAL BIOLOGY

Protein-linked Ubiquitin Chain Structure Restricts Activity of Deubiquitinating Enzymes

(2011) Jonathan B. Schaefer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion

(2011) F. Anton et al.   JOURNAL OF CELL SCIENCE

Sequential requirements for the GTPase domain of the mitofusin Fzo1 and the ubiquitin ligase SCFMdm30 in mitochondrial outer membrane fusion

(2011) M. M. Cohen et al.   JOURNAL OF CELL SCIENCE

Systematic exploration of essential yeast gene function with temperature-sensitive mutants

(2011) Zhijian Li et al.   NATURE BIOTECHNOLOGY

Cdc48 and Ufd3, new partners of the ubiquitin protease Ubp3, are required for ribophagy

(2010) Batool Ossareh-Nazari et al.   EMBO REPORTS

Regulatory mechanisms involved in the control of ubiquitin homeostasis

(2010) Y. Kimura et al.   JOURNAL OF BIOCHEMISTRY

Activity and Cellular Functions of the Deubiquitinating Enzyme and Polyglutamine Disease Protein Ataxin-3 Are Regulated by Ubiquitination at Lysine 117

(2010) Sokol V. Todi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover

(2010) Shan Xu et al.   MOLECULAR BIOLOGY OF THE CELL

A Stress-Responsive System for Mitochondrial Protein Degradation

(2010) Jin-Mi Heo et al.   MOLECULAR CELL

Physiologically relevant and portable tandem ubiquitin-binding domain stabilizes polyubiquitylated proteins

(2010) A. Tyrrell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ubiquitin–Proteasome-dependent Degradation of a Mitofusin, a Critical Regulator of Mitochondrial Fusion

(2008) Mickael M.J. Cohen et al.   MOLECULAR BIOLOGY OF THE CELL