Mitofusin-2 knockdown increases ER-mitochondria contact and decreases amyloid β-peptide production

Mitochondria-Associated Membranes: Composition, Molecular Mechanisms, and Physiopathological Implications

(2015) Carlotta Giorgi et al.   ANTIOXIDANTS & REDOX SIGNALING

ApoE4 upregulates the activity of mitochondria-associated ER membranes

(2015) M. D. Tambini et al.   EMBO REPORTS

Proton myo-inositol cotransporter is a novel γ-secretase associated protein that regulates Aβ production without affecting Notch cleavage

(2015) Yasuhiro Teranishi et al.   FEBS Journal

Amyloid beta-protein and lipid rafts focused on biogenesis and catabolism

(2015) Wataru Araki   Frontiers in Bioscience-Landmark

Distinct mechanisms controlling rough and smooth endoplasmic reticulum contacts with mitochondria

(2015) P. T. C. Wang et al.   JOURNAL OF CELL SCIENCE

A review on Alzheimer's disease pathophysiology and its management: an update

(2015) Anil Kumar et al.   Pharmacological Reports

Mitofusin 2 ablation increases endoplasmic reticulum–mitochondria coupling

(2015) Riccardo Filadi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acute ER stress regulates amyloid precursor protein processing through ubiquitin-dependent degradation

(2015) Eun Sun Jung et al.   Scientific Reports

Presenilin 1 Maintains Lysosomal Ca2+ Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification

(2015) Ju-Hyun Lee et al.   Cell Reports

Complex regulation of γ-secretase: from obligatory to modulatory subunits

(2015) Natalya Gertsik et al.   Frontiers in Aging Neuroscience

At the right distance: ER-mitochondria juxtaposition in cell life and death

(2014) Deborah Naon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity

(2014) Ana Paula Arruda et al.   NATURE MEDICINE

MAM (mitochondria-associated membranes) in mammalian cells: Lipids and beyond

(2013) Jean E. Vance   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Depressing Mitochondria-Reticulum Interactions Protects Cardiomyocytes From Lethal Hypoxia-Reoxygenation Injury

(2013) Melanie Paillard et al.   CIRCULATION

The role of protein glycosylation in Alzheimer disease

(2013) Sophia Schedin-Weiss et al.   FEBS Journal

In-depth proteomic analysis of mammalian mitochondria-associated membranes (MAM)

(2013) Chloe N. Poston et al.   Journal of Proteomics

Autophagosomes form at ER–mitochondria contact sites

(2013) Maho Hamasaki et al.   NATURE

Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models

(2013) L. Hedskog et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The very many faces of presenilins and the γ-secretase complex

(2013) Michalina Smolarkiewicz et al.   PROTOPLASMA

Neprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer’s Disease

(2013) Marcus O. W. Grimm et al.   Frontiers in Aging Neuroscience

2012 Alzheimer’s disease facts and figures

(2012)   Alzheimers & Dementia

Alzheimer's Disease: Critical Notes on the History of a Medical Concept

(2012) Jesus Ramirez-Bermudez   ARCHIVES OF MEDICAL RESEARCH

Where the endoplasmic reticulum and the mitochondrion tie the knot: The mitochondria-associated membrane (MAM)

(2012) Arun Raturi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

(2012) Estela Area-Gomez et al.   EMBO JOURNAL

Identification of Novel γ-Secretase-associated Proteins in Detergent-resistant Membranes from Brain

(2012) Ji-Yeun Hur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria as sensors and regulators of calcium signalling

(2012) Rosario Rizzuto et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of two novel synaptic γ-secretase associated proteins that affect amyloid β-peptide levels without altering Notch processing

(2012) Susanne Frykman et al.   NEUROCHEMISTRY INTERNATIONAL

Mitofusin-2 Independent Juxtaposition of Endoplasmic Reticulum and Mitochondria: An Ultrastructural Study

(2012) Pierre Cosson et al.   PLoS One

Assembly of the presenilin γ-/ε-secretase complex

(2011) P. St George-Hyslop et al.   JOURNAL OF NEUROCHEMISTRY

Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk

(2011) E. Zampese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An intimate liaison: spatial organization of the endoplasmic reticulum–mitochondria relationship

(2010) Olga Martins de Brito et al.   EMBO JOURNAL

Ca2+ Hot Spots on the Mitochondrial Surface Are Generated by Ca2+ Mobilization from Stores, but Not by Activation of Store-Operated Ca2+ Channels

(2010) Marta Giacomello et al.   MOLECULAR CELL

Imaging Interorganelle Contacts and Local Calcium Dynamics at the ER-Mitochondrial Interface

(2010) György Csordás et al.   MOLECULAR CELL

Presenilins Are Enriched in Endoplasmic Reticulum Membranes Associated with Mitochondria

(2009) Estela Area-Gomez et al.   AMERICAN JOURNAL OF PATHOLOGY

Cholesterol in Alzheimers Disease: Unresolved Questions

(2009) Massimo Stefani et al.   Current Alzheimer Research

The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer’s disease

(2009) Xinglong Wang et al.   JOURNAL OF NEUROCHEMISTRY

Fatty Acid Composition of Frontal, Temporal and Parietal Neocortex in the Normal Human Brain and in Alzheimer’s Disease

(2009) Thomas Fraser et al.   NEUROCHEMICAL RESEARCH

MAM: more than just a housekeeper

(2009) Teruo Hayashi et al.   TRENDS IN CELL BIOLOGY

Mitofusin 2 Builds a Bridge between ER and Mitochondria

(2008) Carsten Merkwirth et al.   CELL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

Amplification of neural stem cell proliferation by intermediate progenitor cells in Drosophila brain development

(2008) Bruno C Bello et al.   Neural Development

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

(2008) Ilya Bezprozvanny et al.   TRENDS IN NEUROSCIENCES