- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting Autophagy to Overcome Human Diseases
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 3, Pages 725
Publisher
MDPI AG
Online
2019-02-11
DOI
10.3390/ijms20030725
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- SLC39A8 missense variant is associated with Crohn's disease but does not have a major impact on gut microbiome composition in healthy subjects
- (2019) Valerie Collij et al. PLoS One
- Natural products with anti-aging potential: Affected targets and molecular mechanisms
- (2018) Cristina-Sorina Cătană et al. BIOTECHNOLOGY ADVANCES
- Endoplasmic reticulum quality control by garbage disposal
- (2018) Hisae Kadowaki et al. FEBS Journal
- Autophagic Regulation of p62 is Critical for Cancer Therapy
- (2018) Md. Islam et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial
- (2018) Zhi-Wei Lai et al. LANCET
- Targeting autophagy in obesity: from pathophysiology to management
- (2018) Yingmei Zhang et al. Nature Reviews Endocrinology
- Mechanisms of selective autophagy and mitophagy: Implications for neurodegenerative diseases
- (2018) Charleen T. Chu NEUROBIOLOGY OF DISEASE
- Metabolism as a Target for Modulation in Autoimmune Diseases
- (2018) Nick Huang et al. TRENDS IN IMMUNOLOGY
- Nutraceutical or Pharmacological Potential of Moringa oleifera Lam.
- (2018) Xianjuan Kou et al. Nutrients
- Discovery and validation of autosomal dominant Alzheimer’s disease mutations
- (2018) Simon Hsu et al. Alzheimers Research & Therapy
- Blockade of Treg Cell Differentiation and Function by the Interleukin-21-Mechanistic Target of Rapamycin Axis Via Suppression of Autophagy in Patients With Systemic Lupus Erythematosus
- (2018) Hiroshi Kato et al. Arthritis & Rheumatology
- Calcium signaling in Alzheimer's disease & therapies
- (2018) Benjamin Chun-Kit Tong et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Typical and Atypical Inducers of Lysosomal Cell Death: A Promising Anticancer Strategy
- (2018) Antoni Domagala et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Biomarkers for Alzheimer's disease: current status and prospects for the future
- (2018) K. Blennow et al. JOURNAL OF INTERNAL MEDICINE
- Brain Nrf2 pathway, autophagy, and synaptic function proteins are modulated by a short-term fructose feeding in young and adult rats
- (2018) Maria Stefania Spagnuolo et al. NUTRITIONAL NEUROSCIENCE
- Interaction of Mitochondria with the Endoplasmic Reticulum and Plasma Membrane in Calcium Homeostasis, Lipid Trafficking and Mitochondrial Structure
- (2017) Jędrzej Szymański et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Effects of exercise on obesity-induced mitochondrial dysfunction in skeletal muscle
- (2017) Jun-Won Heo et al. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
- Inflammasome and Autophagy Regulation: A Two-way Street
- (2017) Qian Sun et al. MOLECULAR MEDICINE
- Autophagy maintains the metabolism and function of young and old stem cells
- (2017) Theodore T. Ho et al. NATURE
- Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles
- (2017) Lorenzo Galluzzi et al. NATURE REVIEWS DRUG DISCOVERY
- Dual role of autophagy in hallmarks of cancer
- (2017) Shikha Satendra Singh et al. ONCOGENE
- Silencing of BAG3 promotes the sensitivity of ovarian cancer cells to cisplatin via inhibition of autophagy
- (2017) Shuang Qiu et al. ONCOLOGY REPORTS
- Multifunctional p62 Effects Underlie Diverse Metabolic Diseases
- (2017) Min Long et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Natural products as modulator of autophagy with potential clinical prospects
- (2016) Peiqi Wang et al. APOPTOSIS
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- (2016) Daniel J Klionsky et al. Autophagy
- p62 links the autophagy pathway and the ubiqutin–proteasome system upon ubiquitinated protein degradation
- (2016) Wei Jing Liu et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Regulation of inflammasomes by autophagy
- (2016) Tatsuya Saitoh et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- The regulation of autophagy during exercise in skeletal muscle
- (2016) Anna Vainshtein et al. JOURNAL OF APPLIED PHYSIOLOGY
- Mechanisms of Selective Autophagy
- (2016) Gabriele Zaffagnini et al. JOURNAL OF MOLECULAR BIOLOGY
- Simultaneous activation of Nrf2 and elevation of antioxidant compounds for reducing oxidative stress and chronic inflammation in human Alzheimer's disease
- (2016) Kedar N. Prasad MECHANISMS OF AGEING AND DEVELOPMENT
- Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis
- (2016) Jun Wei et al. NATURE IMMUNOLOGY
- Autophagy in cancer metastasis
- (2016) E E Mowers et al. ONCOGENE
- Autophagy wins the 2016 Nobel Prize in Physiology or Medicine: Breakthroughs in baker's yeast fuel advances in biomedical research
- (2016) Beth Levine et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Non-canonical programmed cell death mechanisms triggered by natural compounds
- (2016) Marc Diederich et al. SEMINARS IN CANCER BIOLOGY
- Ubiquitin-Dependent And Independent Signals In Selective Autophagy
- (2016) Aliaksandr Khaminets et al. TRENDS IN CELL BIOLOGY
- The Autophagy–Lysosomal Pathway in Neurodegeneration: A TFEB Perspective
- (2016) Heidi Martini-Stoica et al. TRENDS IN NEUROSCIENCES
- Resveratrol serves as a protein-substrate interaction stabilizer in human SIRT1 activation
- (2016) Xuben Hou et al. Scientific Reports
- Mitochondrial Dysfunction in the Liver and Antiphospholipid Antibody Production Precede Disease Onset and Respond to Rapamycin in Lupus-Prone Mice
- (2016) Zachary Oaks et al. Arthritis & Rheumatology
- Role of Autophagy as a Survival Mechanism for Hypoxic Cells in Tumors
- (2016) Qian Tan et al. NEOPLASIA
- The critical molecular interconnections in regulating apoptosis and autophagy
- (2015) Gao-Xiang Zhao et al. ANNALS OF MEDICINE
- The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux
- (2015) Valerie R Wiersma et al. Autophagy
- Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions
- (2015) Dhavalkumar D. Patel et al. IMMUNITY
- Mechanisms of inflammasome activation: recent advances and novel insights
- (2015) Sivapriya K. Vanaja et al. TRENDS IN CELL BIOLOGY
- New mechanisms of metformin action: Focusing on mitochondria and the gut
- (2015) Kyu Yeon Hur et al. Journal of Diabetes Investigation
- Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy
- (2015) Laura Poillet-Perez et al. Redox Biology
- Autophagy is activated in systemic lupus erythematosus and required for plasmablast development
- (2014) Alexander J Clarke et al. ANNALS OF THE RHEUMATIC DISEASES
- The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells
- (2014) Stefania Meschini et al. Autophagy
- Autophagy inhibition suppresses the tumorigenic potential of cancer stem cell enriched side population in bladder cancer
- (2014) Rani Ojha et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Rapamycin: One Drug, Many Effects
- (2014) Jing Li et al. Cell Metabolism
- Autophagy and human disease: emerging themes
- (2014) Jaime L Schneider et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- SQSTM1 mutations – Bridging Paget disease of bone and ALS/FTLD
- (2014) Sarah L. Rea et al. EXPERIMENTAL CELL RESEARCH
- PINK1 and Parkin - mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease
- (2014) Agne Kazlauskaite et al. FEBS Journal
- ATG16L1contributes to Crohn's disease susceptibility in Koreans: overmuch concern for ethnic difference?: Table 1
- (2014) Suk-Kyun Yang et al. GUT
- PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
- (2014) Lesley A. Kane et al. JOURNAL OF CELL BIOLOGY
- Mechanistic Target of Rapamycin Complex 1 Expands Th17 and IL-4+ CD4-CD8- Double-Negative T Cells and Contracts Regulatory T Cells in Systemic Lupus Erythematosus
- (2014) H. Kato et al. JOURNAL OF IMMUNOLOGY
- Dietary antiaging phytochemicals and mechanisms associated with prolonged survival
- (2014) Hongwei Si et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Cargo recognition and trafficking in selective autophagy
- (2014) Alexandra Stolz et al. NATURE CELL BIOLOGY
- Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense
- (2014) K. G. Lassen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Application and interpretation of current autophagy inhibitors and activators
- (2013) Ya-ping Yang et al. ACTA PHARMACOLOGICA SINICA
- HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE
- (2013) Tiffany N Caza et al. ANNALS OF THE RHEUMATIC DISEASES
- The ULK1 complex
- (2013) Pui-Mun Wong et al. Autophagy
- Autophagy Inhibition Sensitizes Colon Cancer Cells to Antiangiogenic and Cytotoxic Therapy
- (2013) M. Selvakumaran et al. CLINICAL CANCER RESEARCH
- Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations
- (2013) Suk-Kyun Yang et al. GUT
- p53 status determines the role of autophagy in pancreatic tumour development
- (2013) Mathias T. Rosenfeldt et al. NATURE
- ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
- (2013) Ryan C. Russell et al. NATURE CELL BIOLOGY
- Structural basis for recognition of autophagic receptor NDP52 by the sugar receptor galectin-8
- (2013) Byeong-Won Kim et al. Nature Communications
- Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis
- (2012) George K Bertsias et al. ANNALS OF THE RHEUMATIC DISEASES
- Guidelines for the use and interpretation of assays for monitoring autophagy
- (2012) Daniel J. Klionsky et al. Autophagy
- Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy
- (2012) Rita A. Hanna et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NBR1 acts as an autophagy receptor for peroxisomes
- (2012) E. Deosaran et al. JOURNAL OF CELL SCIENCE
- Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
- (2012) Congcong He et al. NATURE
- Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
- (2012) Chong-Shan Shi et al. NATURE IMMUNOLOGY
- Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine
- (2012) Kook Hwan Kim et al. NATURE MEDICINE
- Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells
- (2012) C Gong et al. ONCOGENE
- Caloric restriction: powerful protection for the aging heart and vasculature
- (2011) Edward P. Weiss et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population
- (2011) X.-j. Zhou et al. ANNALS OF THE RHEUMATIC DISEASES
- The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases
- (2011) Beckley K. Davis et al. Annual Review of Immunology
- Cell death by autophagy: facts and apparent artefacts
- (2011) D Denton et al. CELL DEATH AND DIFFERENTIATION
- Autophagy: Molecular Mechanisms and their Implications for Anticancer Therapies
- (2011) S. Meschini et al. CURRENT CANCER DRUG TARGETS
- Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation
- (2011) James Harris et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding
- (2011) Eisuke Itakura et al. JOURNAL OF CELL BIOLOGY
- NLRP4 Negatively Regulates Autophagic Processes through an Association with Beclin1
- (2011) N. Jounai et al. JOURNAL OF IMMUNOLOGY
- Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins
- (2011) Gen Matsumoto et al. MOLECULAR CELL
- The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
- (2011) Greg M Delgoffe et al. NATURE IMMUNOLOGY
- Utility of mTOR Inhibition in Hematologic Malignancies
- (2011) A. Younes et al. ONCOLOGIST
- Calorie Restriction: Is AMPK a Key Sensor and Effector?
- (2011) Carles Cantó et al. PHYSIOLOGY
- Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth
- (2011) P. Wild et al. SCIENCE
- Regulation of autophagy by phosphatidylinositol 3-phosphate
- (2010) Chloe Burman et al. FEBS LETTERS
- FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end–directed vesicle transport
- (2010) Serhiy Pankiv et al. JOURNAL OF CELL BIOLOGY
- KRAS, BRAF, PIK3CA, and PTEN mutations: implications for targeted therapies in metastatic colorectal cancer
- (2010) Wendy De Roock et al. LANCET ONCOLOGY
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
- (2010) Kiichi Nakahira et al. NATURE IMMUNOLOGY
- Selective Molecular Alterations in the Autophagy Pathway in Patients with Lewy Body Disease and in Models of α-Synucleinopathy
- (2010) Leslie Crews et al. PLoS One
- Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
- (2010) D. F. Egan et al. SCIENCE
- Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy
- (2010) E Morselli et al. Cell Death & Disease
- Malignancies in systemic lupus erythematosus
- (2009) Emese Kiss et al. AUTOIMMUNITY REVIEWS
- NBR1 co-operates with p62 in selective autophagy of ubiquitinated targets
- (2009) Vladimir Kirkin et al. Autophagy
- Autophagy, Not Apoptosis, Is Essential for Midgut Cell Death in Drosophila
- (2009) Donna Denton et al. CURRENT BIOLOGY
- Heat Shock Proteins in Diabetes and Wound Healing
- (2009) Mustafa Atalay et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- The structure of Atg4B–LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy
- (2009) Kenji Satoo et al. EMBO JOURNAL
- Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover
- (2009) Sarah Waters et al. FEBS LETTERS
- A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates
- (2009) Vladimir Kirkin et al. MOLECULAR CELL
- The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
- (2009) Teresa L M Thurston et al. NATURE IMMUNOLOGY
- The Tor and PKA signaling pathways independently target the Atg1/Atg13 protein kinase complex to control autophagy
- (2009) J. S. Stephan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
- (2009) Y. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia
- (2008) Hye Seung Jung et al. Cell Metabolism
- A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
- (2008) Ken Cadwell et al. NATURE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started