PINK1 and Parkin - mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
PINK1 and Parkin - mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease
Authors
Keywords
-
Journal
FEBS Journal
Volume 282, Issue 2, Pages 215-223
Publisher
Wiley
Online
2014-10-25
DOI
10.1111/febs.13127
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- RBR E3 ubiquitin ligases: new structures, new insights, new questions
- (2014) Donald E. Spratt et al. BIOCHEMICAL JOURNAL
- Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
- (2014) Agne Kazlauskaite et al. BIOCHEMICAL JOURNAL
- PTENα, a PTEN Isoform Translated through Alternative Initiation, Regulates Mitochondrial Function and Energy Metabolism
- (2014) Hui Liang et al. Cell Metabolism
- The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy
- (2014) Tom Cornelissen et al. HUMAN MOLECULAR GENETICS
- PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
- (2014) Lesley A. Kane et al. JOURNAL OF CELL BIOLOGY
- Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease
- (2014) Kuldip D. Dave et al. NEUROBIOLOGY OF DISEASE
- PINK1 deficiency in -cells increases basal insulin secretion and improves glucose tolerance in mice
- (2014) E. Deas et al. Open Biology
- Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
- (2014) A. Kazlauskaite et al. Open Biology
- PINK1 is degraded through the N-end rule pathway
- (2013) Koji Yamano et al. Autophagy
- Structure of the human Parkin ligase domain in an autoinhibited state
- (2013) Tobias Wauer et al. EMBO JOURNAL
- Loss of iron triggers PINK1/Parkin-independent mitophagy
- (2013) George F G Allen et al. EMBO REPORTS
- The genetics of Parkinson's disease: Progress and therapeutic implications
- (2013) Andrew B. Singleton et al. MOVEMENT DISORDERS
- Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
- (2013) Shireen A. Sarraf et al. NATURE
- Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation
- (2013) J.-F. Trempe et al. SCIENCE
- Mitochondrial Trafficking in Neurons
- (2013) T. L. Schwarz Cold Spring Harbor Perspectives in Biology
- Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
- (2013) B.E. Riley et al. Nature Communications
- Regulation of Parkin E3 ubiquitin ligase activity
- (2012) Helen Walden et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
- (2012) Michael Lazarou et al. DEVELOPMENTAL CELL
- Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
- (2012) Andrew W Greene et al. EMBO REPORTS
- PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria
- (2012) Kei Okatsu et al. Nature Communications
- PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
- (2012) Kahori Shiba-Fukushima et al. Scientific Reports
- PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
- (2012) C. Kondapalli et al. Open Biology
- Autoregulation of Parkin activity through its ubiquitin-like domain
- (2011) Viduth K Chaugule et al. EMBO JOURNAL
- Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy
- (2011) Nickie C. Chan et al. HUMAN MOLECULAR GENETICS
- UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
- (2011) Dawn M. Wenzel et al. NATURE
- Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations
- (2011) H. I. Woodroof et al. Open Biology
- PINK1 cleavage at position A103 by the mitochondrial protease PARL
- (2010) Emma Deas et al. HUMAN MOLECULAR GENETICS
- Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
- (2010) Seok Min Jin et al. JOURNAL OF CELL BIOLOGY
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-Induced Cell Death
- (2009) Sonia Gandhi et al. MOLECULAR CELL
- Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies
- (2009) Selvaraju Veeriah et al. NATURE GENETICS
- PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
- (2009) C. Vives-Bauza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin
- (2008) A. J. Whitworth et al. Disease Models & Mechanisms
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- Characterization of PINK1 processing, stability, and subcellular localization
- (2008) William Lin et al. JOURNAL OF NEUROCHEMISTRY
- The kinase domain of mitochondrial PINK1 faces the cytoplasm
- (2008) C. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now