- Home
- Publications
- Publication Search
- Publication Details
Title
Insulin Resistance in Alzheimer's Disease
Authors
Keywords
-
Journal
Frontiers in Neuroscience
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-11-13
DOI
10.3389/fnins.2018.00830
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer's disease
- (2018) Jingjing Tai et al. BRAIN RESEARCH
- Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States
- (2018) Mark P. Mattson et al. Cell Metabolism
- Lipid Biomarkers in Alzheimer's Disease
- (2018) Amira Zarrouk et al. Current Alzheimer Research
- Safety of intranasal human insulin: A review
- (2018) Vera Schmid et al. DIABETES OBESITY & METABOLISM
- An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation
- (2018) Richard G. Carroll et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Insulin regulates astrocyte gliotransmission and modulates behavior
- (2018) Weikang Cai et al. JOURNAL OF CLINICAL INVESTIGATION
- The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease
- (2018) Andre F Batista et al. JOURNAL OF PATHOLOGY
- Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease
- (2018) Seung Pil Yun et al. NATURE MEDICINE
- Glucagon-like peptide 1 in health and disease
- (2018) Andreas Andersen et al. Nature Reviews Endocrinology
- Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications
- (2018) Geert Jan Biessels et al. Nature Reviews Endocrinology
- Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums
- (2018) Steven E. Arnold et al. Nature Reviews Neurology
- Brain insulin signalling, glucose metabolism and females' reproductive aging: A dangerous triad in Alzheimer's disease
- (2018) A.I. Duarte et al. NEUROPHARMACOLOGY
- Connecting Alzheimer's disease to diabetes: Underlying mechanisms and potential therapeutic targets
- (2018) Marcelo N.N. Vieira et al. NEUROPHARMACOLOGY
- Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer’s Disease
- (2018) Michael F. Egan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Trial of Solanezumab for Mild Dementia Due to Alzheimer’s Disease
- (2018) Lawrence S. Honig et al. NEW ENGLAND JOURNAL OF MEDICINE
- Normal aging induces A1-like astrocyte reactivity
- (2018) Laura E. Clarke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hippocampal insulin resistance links maternal obesity with impaired neuronal plasticity in adult offspring
- (2018) Lisa Schmitz et al. PSYCHONEUROENDOCRINOLOGY
- Insulin-Degrading Enzyme in the Fight against Alzheimer’s Disease
- (2018) Igor V. Kurochkin et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes
- (2018) Sreemathi Logan et al. Molecular Metabolism
- Th17 and Treg lymphocytes in obesity and Type 2 diabetic patients
- (2018) Mei Wang et al. CLINICAL IMMUNOLOGY
- The Role of Rho-GEF Trio in Regulating Tooth Root Development through the p38 MAPK Pathway
- (2018) Huimin Chen et al. EXPERIMENTAL CELL RESEARCH
- Trends in Diet and Alzheimer's Disease During the Nutrition Transition in Japan and Developing Countries
- (2018) William B. Grant JOURNAL OF ALZHEIMERS DISEASE
- The Rotterdam Study: 2018 update on objectives, design and main results
- (2017) M. Arfan Ikram et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Exosomal biomarkers of brain insulin resistance associated with regional atrophy in Alzheimer's disease
- (2017) Roger J. Mullins et al. HUMAN BRAIN MAPPING
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
- Reactive Astrocytes: Production, Function, and Therapeutic Potential
- (2017) Shane A. Liddelow et al. IMMUNITY
- Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers
- (2017) Jason Pitt et al. MOLECULAR BIOLOGY OF THE CELL
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes
- (2017) Na Zhao et al. NEURON
- Behavioral changes in male mice fed a high-fat diet are associated with IL-1β expression in specific brain regions
- (2017) Camila P. Almeida-Suhett et al. PHYSIOLOGY & BEHAVIOR
- Antidiabetic Drugs in Alzheimer’s Disease: Mechanisms of Action and Future Perspectives
- (2017) Grazia Daniela Femminella et al. Journal of Diabetes Research
- Intranasal Insulin Administration Dose-Dependently Modulates Verbal Memory and Plasma Amyloid-β in Memory-Impaired Older Adults
- (2017) Mark A. Reger et al. JOURNAL OF ALZHEIMERS DISEASE
- Depression in Alzheimer's Disease. Pathophysiology, Diagnosis, and Treatment
- (2017) Pedro J. Modrego JOURNAL OF ALZHEIMERS DISEASE
- Entorhinal Cortex dysfunction can be rescued by inhibition of microglial RAGE in an Alzheimer’s disease mouse model
- (2017) Chiara Criscuolo et al. Scientific Reports
- Functional polarization of neuroglia: Implications in neuroinflammation and neurological disorders
- (2016) Mithilesh Kumar Jha et al. BIOCHEMICAL PHARMACOLOGY
- Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability
- (2016) Cristina García-Cáceres et al. CELL
- Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I
- (2016) Ana M. Fernandez et al. DIABETES
- Modulation of GLP-1 signaling as a novel therapeutic approach in the treatment of Alzheimer’s disease pathology
- (2016) Antonella Tramutola et al. Expert Review of Neurotherapeutics
- Mechanisms of microglial activation in models of inflammation and hypoxia: Implications for chronic intermittent hypoxia
- (2016) Elizabeth A. Kiernan et al. JOURNAL OF PHYSIOLOGY-LONDON
- PTEN recruitment controls synaptic and cognitive function in Alzheimer's models
- (2016) Shira Knafo et al. NATURE NEUROSCIENCE
- Brain Insulin Resistance at the Crossroads of Metabolic and Cognitive Disorders in Humans
- (2016) Stephanie Kullmann et al. PHYSIOLOGICAL REVIEWS
- The BACE1 inhibitor verubecestat (MK-8931) reduces CNS -amyloid in animal models and in Alzheimers disease patients
- (2016) M. E. Kennedy et al. Science Translational Medicine
- In Alzheimer’s Disease, 6-Month Treatment with GLP-1 Analog Prevents Decline of Brain Glucose Metabolism: Randomized, Placebo-Controlled, Double-Blind Clinical Trial
- (2016) Michael Gejl et al. Frontiers in Aging Neuroscience
- Modulation of GLP-1 signaling as a novel therapeutic approach in the treatment of Alzheimer’s disease pathology
- (2016) Antonella Tramutola et al. Expert Review of Neurotherapeutics
- Efficacy and safety of gantenerumab in prodromal Alzheimer’s disease: Results from scarlet road—a global, multicenter trial
- (2015) Robert Lasser et al. Alzheimers & Dementia
- Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective
- (2015) Matthew Baumgart et al. Alzheimers & Dementia
- Western diet is associated with a smaller hippocampus: a longitudinal investigation
- (2015) Felice N. Jacka et al. BMC Medicine
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- Role of RAGE in Alzheimer’s Disease
- (2015) Zhiyou Cai et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Insulin Modulates In Vitro Secretion of Cytokines and Cytotoxins by Human Glial Cells
- (2015) Lindsay Spielman et al. Current Alzheimer Research
- Insulin Resistance Predicts Medial Temporal Hypermetabolism in Mild Cognitive Impairment Conversion to Alzheimer Disease
- (2015) Auriel A. Willette et al. DIABETES
- Alzheimer-associated A oligomers impact the central nervous system to induce peripheral metabolic deregulation
- (2015) J. R. Clarke et al. EMBO Molecular Medicine
- Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer’s disease
- (2015) Dimitrios Kapogiannis et al. FASEB JOURNAL
- TREM2 deficiency eliminates TREM2+inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models
- (2015) Taylor R. Jay et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Aβ1-42oligomer-induced leakage in anin vitroblood-brain barrier model is associated with up-regulation of RAGE and metalloproteinases, and down-regulation of tight junction scaffold proteins
- (2015) Wenbin Wan et al. JOURNAL OF NEUROCHEMISTRY
- Intranasal Neuropeptide Administration To Target the Human Brain in Health and Disease
- (2015) Maartje S. Spetter et al. MOLECULAR PHARMACEUTICS
- Amyloid cascade hypothesis: Pathogenesis and therapeutic strategies in Alzheimer's disease
- (2015) Sagar H. Barage et al. NEUROPEPTIDES
- Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer’s disease and tauopathies
- (2014) Mark Yarchoan et al. ACTA NEUROPATHOLOGICA
- Insulin Action in Brain Regulates Systemic Metabolism and Brain Function
- (2014) A. Kleinridders et al. DIABETES
- Sex differences in cognitive impairment and Alzheimer’s disease
- (2014) Rena Li et al. FRONTIERS IN NEUROENDOCRINOLOGY
- Human Apolipoprotein E ε4 Expression Impairs Cerebral Vascularization and Blood—Brain Barrier Function in Mice
- (2014) Wael Alata et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- The role of adipose tissue immune cells in obesity and low-grade inflammation
- (2014) Milos Mraz et al. JOURNAL OF ENDOCRINOLOGY
- Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014
- (2014) L. S. Schneider et al. JOURNAL OF INTERNAL MEDICINE
- Alzheimer's Disease-Like Pathology Induced by Amyloid-β Oligomers in Nonhuman Primates
- (2014) Leticia Forny-Germano et al. JOURNAL OF NEUROSCIENCE
- Microglial Cell Activation Increases Saturated and Decreases Monounsaturated Fatty Acid Content, but Both Lipid Species are Proinflammatory
- (2014) Emily B. Button et al. LIPIDS
- High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice
- (2014) Steven E. Arnold et al. NEUROBIOLOGY OF DISEASE
- Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease
- (2014) Stephen Salloway et al. NEW ENGLAND JOURNAL OF MEDICINE
- Aβ1–42 reduces P-glycoprotein in the blood–brain barrier through RAGE–NF-κB signaling
- (2014) R Park et al. Cell Death & Disease
- BACE1 inhibitor drugs in clinical trials for Alzheimer’s disease
- (2014) Robert Vassar Alzheimers Research & Therapy
- Insulin as a Bridge between Type 2 Diabetes and Alzheimer Disease – How Anti-Diabetics Could be a Solution for Dementia
- (2014) Inês Sebastião et al. Frontiers in Endocrinology
- Genetics of Alzheimer Disease
- (2013) A.T. Rao et al. AMERICAN JOURNAL OF NEURORADIOLOGY
- Crosstalk between diabetes and brain: Glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration
- (2013) A.I. Duarte et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys
- (2013) Mychael V. Lourenco et al. Cell Metabolism
- Increased Alzheimer’s Disease Neuropathology is Associated with Type 2 Diabetes and ApoE ε4 Carrier Status
- (2013) Michael Malek-Ahmadi et al. Current Alzheimer Research
- The potential mechanisms of Aβ-receptor for advanced glycation end-products interaction disrupting tight junctions of the blood-brain barrier in Alzheimer's disease
- (2013) Wenbin Wan et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Alzheimer’s disease and insulin resistance: translating basic science into clinical applications
- (2013) Fernanda G. De Felice JOURNAL OF CLINICAL INVESTIGATION
- Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer's disease
- (2013) Paula L. McClean et al. NEUROPHARMACOLOGY
- Glucose Levels and Risk of Dementia
- (2013) Paul K. Crane et al. NEW ENGLAND JOURNAL OF MEDICINE
- The immune system's involvement in obesity-driven type 2 diabetes
- (2013) Chengyi Jenny Shu et al. SEMINARS IN IMMUNOLOGY
- Mechanisms of Inflammatory Responses in Obese Adipose Tissue
- (2012) Shengyi Sun et al. Annual Review of Nutrition
- The Critical Role of Metabolic Pathways in Aging
- (2012) N. Barzilai et al. DIABETES
- The many faces of insulin-like peptide signalling in the brain
- (2012) Ana M. Fernandez et al. NATURE REVIEWS NEUROSCIENCE
- Rosiglitazone and Pioglitazone for the Treatment of Alzheimer's Disease
- (2011) Benjamin W Miller et al. ANNALS OF PHARMACOTHERAPY
- Ursolic acid improves high fat diet-induced cognitive impairments by blocking endoplasmic reticulum stress and IκB kinase β/nuclear factor-κB-mediated inflammatory pathways in mice
- (2011) Jun Lu et al. BRAIN BEHAVIOR AND IMMUNITY
- Saturated fatty acids activate microglia via Toll-like receptor 4/NF-κB signalling
- (2011) Zhen Wang et al. BRITISH JOURNAL OF NUTRITION
- Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation
- (2011) Mireille Bélanger et al. Cell Metabolism
- Rosiglitazone Does Not Improve Cognition or Global Function when Used as Adjunctive Therapy to AChE Inhibitors in Mild-to-Moderate Alzheimers Disease: Two Phase 3 Studies
- (2011) C. Harrington et al. Current Alzheimer Research
- The Diabetes Drug Liraglutide Prevents Degenerative Processes in a Mouse Model of Alzheimer's Disease
- (2011) P. L. McClean et al. JOURNAL OF NEUROSCIENCE
- Insulin Resistance and Alzheimer-like Reductions in Regional Cerebral Glucose Metabolism for Cognitively Normal Adults With Prediabetes or Early Type 2 Diabetes
- (2010) Laura D. Baker et al. ARCHIVES OF NEUROLOGY
- Insulin resistance is associated with the pathology of Alzheimer disease: The Hisayama Study
- (2010) T. Matsuzaki et al. NEUROLOGY
- Rosiglitazone Rescues Memory Impairment in Alzheimer's Transgenic Mice: Mechanisms Involving a Reduced Amyloid and Tau Pathology
- (2010) Luis Escribano et al. NEUROPSYCHOPHARMACOLOGY
- Feed-forward signaling of TNF-α and NF-κB via IKK-β pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice
- (2009) Jiyeon Yang et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- -Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin
- (2009) Q.-L. Ma et al. JOURNAL OF NEUROSCIENCE
- Correction for Reed et al., Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys
- (2009) PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amyloid- Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle
- (2009) J.-E. Kang et al. SCIENCE
- Obesity and Free Fatty Acids
- (2008) Guenther Boden ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
- Differential Sensitivity of Men and Women to Anorexigenic and Memory-Improving Effects of Intranasal Insulin
- (2008) Christian Benedict et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started