Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

Peripheral monocyte entry is required for alpha-Synuclein induced inflammation and Neurodegeneration in a model of Parkinson disease

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Both classic Gs-cAMP/PKA/CREB and alternative Gs-cAMP/PKA/p38β/CREB signal pathways mediate exenatide-stimulated expression of M2 microglial markers

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GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers

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Best Practices for Generating and Using Alpha-Synuclein Pre-Formed Fibrils to Model Parkinson’s Disease in Rodents

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Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial

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Activation of Glucagon-Like Peptide-1 Receptor Promotes Neuroprotection in Experimental Autoimmune Encephalomyelitis by Reducing Neuroinflammatory Responses

(2017) Chi-Ho Lee et al.   MOLECULAR NEUROBIOLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

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Exendin-4 Treatment Improves LPS-Induced Depressive-Like Behavior Without Affecting Pro-Inflammatory Cytokines

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Plant Polyphenols and Exendin-4 Prevent Hyperactivity and TNF-α Release in LPS-Treated In vitro Neuron/Astrocyte/Microglial Networks

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Blast traumatic brain injury–induced cognitive deficits are attenuated by preinjury or postinjury treatment with the glucagon-like peptide-1 receptor agonist, exendin-4

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A novel dual GLP-1 and GIP receptor agonist is neuroprotective in the MPTP mouse model of Parkinson′s disease by increasing expression of BNDF

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The glucagon-like peptide 1 (GLP) receptor as a therapeutic target in Parkinson's disease: mechanisms of action

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Activation of tyrosine kinase c-Abl contributes to α-synuclein–induced neurodegeneration

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Pathological  -synuclein transmission initiated by binding lymphocyte-activation gene 3

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A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1

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Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2

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Striatal Blood–Brain Barrier Permeability in Parkinson'S Disease

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Liraglutide is neurotrophic and neuroprotective in neuronal cultures and mitigates mild traumatic brain injury in mice

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Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's Disease

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An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

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Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates

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Astrocytic modulation of blood brain barrier: perspectives on Parkinson’s disease

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Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss

(2013) Yunjong Lee et al.   NATURE NEUROSCIENCE

Glucagon-like peptide-1 protects hippocampal neurons against advanced glycation end product-induced tau hyperphosphorylation

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Exendin-4 induced glucagon-like peptide-1 receptor activation reverses behavioral impairments of mild traumatic brain injury in mice

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Site-Specific PEGylated Exendin-4 Modified with a High Molecular Weight Trimeric PEG Reduces Steric Hindrance and Increases Type 2 Antidiabetic Therapeutic Effects

(2012) Tae Hyung Kim et al.   BIOCONJUGATE CHEMISTRY

Neuroprotective and neurotrophic actions of glucagon-like peptide-1: an emerging opportunity to treat neurodegenerative and cerebrovascular disorders

(2012) Isidro Salcedo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neurodegenerative phenotypes in an A53T  -synuclein transgenic mouse model are independent of LRRK2

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GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus

(2012) Juris J. Meier   Nature Reviews Endocrinology

Pathological  -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

(2012) K. C. Luk et al.   SCIENCE

Mono-PEGylated Dimeric Exendin-4 as High Receptor Binding and Long-Acting Conjugates for Type 2 Anti-Diabetes Therapeutics

(2011) Tae Hyung Kim et al.   BIOCONJUGATE CHEMISTRY

Exendin-4, a Glucagon-Like Peptide-1 Receptor Agonist, Provides Neuroprotection in Mice Transient Focal Cerebral Ischemia

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Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death

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Glucagon-like peptide 1 receptor stimulation as a means of neuroprotection

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Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinson's disease

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GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

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