Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes

Title
Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes
Authors
Keywords
Alzheimer’s disease, APOE, Insulin signaling, Aging, Endosomal dysfunction, Trafficking, Aggregation
Journal
NEURON
Volume 96, Issue 1, Pages 115-129.e5
Publisher
Elsevier BV
Online
2017-09-28
DOI
10.1016/j.neuron.2017.09.003

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