The potential mechanisms of Aβ-receptor for advanced glycation end-products interaction disrupting tight junctions of the blood-brain barrier in Alzheimer's disease

Role of ABC Transporters in the Pathogenesis of Alzheimer’s Disease

(2012) Alaa H. Abuznait et al.   ACS Chemical Neuroscience

Inhibition of c-Jun N-terminal kinase prevents blood–brain barrier disruption and normalizes the expression of tight junction proteins clautin-5 and ZO-1 in a rat model of subarachnoid hemorrhage

(2012) Duo Chen et al.   ACTA NEUROCHIRURGICA

AGEs Induce Cell Death via Oxidative and Endoplasmic Reticulum Stresses in Both Human SH-SY5Y Neuroblastoma Cells and Rat Cortical Neurons

(2012) Qing-Qing Yin et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Tight Junction in Blood-Brain Barrier: An Overview of Structure, Regulation, and Regulator Substances

(2012) Wei-Ye Liu et al.   CNS Neuroscience & Therapeutics

Blood-Brain Barrier Integrity and Glial Support: Mechanisms that can be Targeted for Novel Therapeutic Approaches in Stroke

(2012) Patrick T. Ronaldson et al.   CURRENT PHARMACEUTICAL DESIGN

Is RAGE still a therapeutic target for Alzheimer’s disease?

(2012) Richard J Deane   Future Medicinal Chemistry

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

(2012) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

A 1-42-RAGE Interaction Disrupts Tight Junctions of the Blood-Brain Barrier Via Ca2+-Calcineurin Signaling

(2012) S.-Y. Kook et al.   JOURNAL OF NEUROSCIENCE

Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE) - and amyloid beta 1-42-induced signal transduction in glial cells

(2012) Alexander Slowik et al.   Molecular Neurodegeneration

Tight Junctions in Brain Barriers During Central Nervous System Inflammation

(2011) Caroline Coisne et al.   ANTIOXIDANTS & REDOX SIGNALING

Amyloid Beta Induces Oxidative Stress-Mediated Blood–Brain Barrier Changes in Capillary Amyloid Angiopathy

(2011) Anna Carrano et al.   ANTIOXIDANTS & REDOX SIGNALING

The Interaction of Amyloid β and the Receptor for Advanced Glycation Endproducts Induces Matrix Metalloproteinase-2 Expression in Brain Endothelial Cells

(2011) Huan Du et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke

(2011) Kim M. Baeten et al.   Developmental Neurobiology

Involvement of RAGE, MAPK and NF-κB pathways in AGEs-induced MMP-9 activation in HaCaT keratinocytes

(2011) Ping Zhu et al.   EXPERIMENTAL DERMATOLOGY

Alzheimer's dementia begins as a disease of small blood vessels, damaged by oxidative-induced inflammation and dysregulated amyloid metabolism: implications for early detection and therapy

(2011) Vincent T. Marchesi   FASEB JOURNAL

AMP-activated Protein Kinase (AMPK) Activation and Glycogen Synthase Kinase-3β (GSK-3β) Inhibition Induce Ca2+-independent Deposition of Tight Junction Components at the Plasma Membrane

(2011) Li Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aβ-Degrading Enzymes: Potential for Treatment of Alzheimer Disease

(2011) James Scott Miners et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

RAGE: The beneficial and deleterious effects by diverse mechanisms of actions

(2011) Sun-Ho Han et al.   MOLECULES AND CELLS

Amyloid Triggers Extensive Cerebral Angiogenesis Causing Blood Brain Barrier Permeability and Hypervascularity in Alzheimer's Disease

(2011) Kaan E. Biron et al.   PLoS One

ABC Transporters and Drug Efflux at the Blood-Brain Barrier

(2011) Shanshan Shen et al.   REVIEWS IN THE NEUROSCIENCES

RAGE: a single receptor fits multiple ligands

(2011) Günter Fritz   TRENDS IN BIOCHEMICAL SCIENCES

PF-04494700, an Oral Inhibitor of Receptor for Advanced Glycation End Products (RAGE), in Alzheimer Disease

(2010) Marwan N. Sabbagh et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Soluble RAGE: Therapy and biomarker in unraveling the RAGE axis in chronic disease and aging

(2010) Shi Fang Yan et al.   BIOCHEMICAL PHARMACOLOGY

Is P-glycoprotein Involved in Amyloid-β Elimination Across the Blood–Brain Barrier in Alzheimer’s Disease?

(2010) S Ohtsuki et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clearance of Amyloid-β Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimers Disease

(2009) R. Deane et al.   CNS & Neurological Disorders-Drug Targets

MAPK, β-amyloid and synaptic dysfunction: the role of RAGE

(2009) Nicola Origlia et al.   Expert Review of Neurotherapeutics

Insights into the pathogenesis and pathogenicity of cerebral amyloid angiopathy

(2009) Seth Love   Frontiers in Bioscience-Landmark

Cellular Elements of the Blood-Brain Barrier

(2009) Jorge Correale et al.   NEUROCHEMICAL RESEARCH

Effects of ginkgo biloba extract EGb761 on expression of RAGE and LRP-1 in cerebral microvascular endothelial cells under chronic hypoxia and hypoglycemia

(2008) Fu-Ling Yan et al.   ACTA NEUROPATHOLOGICA

Inflammation and the Redox-sensitive AGE-RAGE Pathway as a Therapeutic Target in Alzheimer's Disease

(2008) Annette Maczurek et al.   Annals of the New York Academy of Sciences

Therapeutic application of gene silencing MMP-9 in a middle cerebral artery occlusion-induced focal ischemia rat model

(2008) Qin Hu et al.   EXPERIMENTAL NEUROLOGY

Cerebrovascular Dysfunction in Amyloid Precursor Protein Transgenic Mice: Contribution of Soluble and Insoluble Amyloid-  Peptide, Partial Restoration via  -Secretase Inhibition

(2008) B. H. Han et al.   JOURNAL OF NEUROSCIENCE

Microglial Dysfunction and Defective  -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

(2008) S. E. Hickman et al.   JOURNAL OF NEUROSCIENCE

Tight Junction Proteins Claudin-2 and -12 Are Critical for Vitamin D-dependent Ca2+ Absorption between Enterocytes

(2008) Hiroki Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON