Exosomal biomarkers of brain insulin resistance associated with regional atrophy in Alzheimer's disease

Brain atrophy in Alzheimer’s Disease and aging

(2016) Lorenzo Pini et al.   AGEING RESEARCH REVIEWS

Insulin resistance predicts brain amyloid deposition in late middle-aged adults

(2015) Auriel A. Willette et al.   Alzheimers & Dementia

Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study

(2015) Massimo S. Fiandaca et al.   Alzheimers & Dementia

Insulin Resistance Predicts Medial Temporal Hypermetabolism in Mild Cognitive Impairment Conversion to Alzheimer Disease

(2015) Auriel A. Willette et al.   DIABETES

Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer’s disease

(2015) Dimitrios Kapogiannis et al.   FASEB JOURNAL

Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease

(2015) Edward J. Goetzl et al.   NEUROLOGY

Association of Insulin Resistance With Cerebral Glucose Uptake in Late Middle–Aged Adults at Risk for Alzheimer Disease

(2015) Auriel A. Willette et al.   JAMA Neurology

Voxel-based meta-analysis of grey matter changes in Alzheimer’s disease

(2015) Wen-Ying Wang et al.   Translational Neurodegeneration

The nature, significance, and glucagon-like peptide-1 analog treatment of brain insulin resistance in Alzheimer's disease

(2014) Konrad Talbot et al.   Alzheimers & Dementia

Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease

(2014) F. G. De Felice et al.   DIABETES

Insulin Regulates Brain Function, but How Does It Get There?

(2014) S. M. Gray et al.   DIABETES

Cluster-extent based thresholding in fMRI analyses: Pitfalls and recommendations

(2014) Choong-Wan Woo et al.   NEUROIMAGE

mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies

(2013) Antonella Caccamo et al.   AGING CELL

Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology

(2013) Miranda E. Orr et al.   NEUROBIOLOGY OF AGING

Glucose Levels and Risk of Dementia

(2013) Paul K. Crane et al.   NEW ENGLAND JOURNAL OF MEDICINE

Insulin Resistance, Brain Atrophy, and Cognitive Performance in Late Middle-Aged Adults

(2012) A. A. Willette et al.   DIABETES CARE

Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

(2012) K. D. Copps et al.   DIABETOLOGIA

An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers

(2012) Theresa R. Bomfim et al.   JOURNAL OF CLINICAL INVESTIGATION

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

(2012) Konrad Talbot et al.   JOURNAL OF CLINICAL INVESTIGATION

An anatomically comprehensive atlas of the adult human brain transcriptome

(2012) Michael J. Hawrylycz et al.   NATURE

Insulin resistance and AD—extending the translational path

(2012) Suzanne Craft   Nature Reviews Neurology

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Insulin resistance and Alzheimer's disease

(2011) Suzanne M. De La Monte   BMB Reports

Insulin Resistance and Alzheimer-like Reductions in Regional Cerebral Glucose Metabolism for Cognitively Normal Adults With Prediabetes or Early Type 2 Diabetes

(2010) Laura D. Baker et al.   ARCHIVES OF NEUROLOGY

Insulin metabolism and the risk of Alzheimer disease: The Rotterdam Study

(2010) E. M. C. Schrijvers et al.   NEUROLOGY

Insulin-stimulated translocation of GLUT4 to the plasma membrane in rat hippocampus is PI3-kinase dependent

(2009) C.A. Grillo et al.   BRAIN RESEARCH

 -Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin

(2009) Q.-L. Ma et al.   JOURNAL OF NEUROSCIENCE

IRS1-Independent Defects Define Major Nodes of Insulin Resistance

(2008) Kyle L. Hoehn et al.   Cell Metabolism

L1 and NCAM adhesion molecules as signaling coreceptors in neuronal migration and process outgrowth

(2008) Ralf S Schmid et al.   CURRENT OPINION IN NEUROBIOLOGY