Sarcopenia: Aging-Related Loss of Muscle Mass and Function

Sirtuins in mitochondrial stress: Indispensable helpers behind the scenes

(2018) Shuangzhe Lin et al.   AGEING RESEARCH REVIEWS

Impairment of an Endothelial NAD + -H 2 S Signaling Network Is a Reversible Cause of Vascular Aging

(2018) Abhirup Das et al.   CELL

Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers

(2018) Chengcheng Li et al.   EXPERIMENTAL GERONTOLOGY

The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms

(2018) Inhae Kang et al.   FEBS LETTERS

Relationship of Physical Function to Single Muscle Fiber Contractility in Older Adults: Effects of Resistance Training With and Without Caloric Restriction

(2018) Zhong-Min Wang et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle

(2018) Graham P. Holloway et al.   Cell Reports

Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibody

(2018) Sarah Cantor et al.   eLife

Physical activity unveils the relationship between mitochondrial energetics, muscle quality, and physical function in older adults

(2018) Giovanna Distefano et al.   Journal of Cachexia Sarcopenia and Muscle

Physical exercise increases Sestrin 2 protein levels and induces autophagy in the skeletal muscle of old mice

(2017) Luciene Lenhare et al.   EXPERIMENTAL GERONTOLOGY

Structure and function of human muscle fibres and muscle proteome in physically active older men

(2017) Lorenza Brocca et al.   JOURNAL OF PHYSIOLOGY-LONDON

Nutritional Supplementation With Physical Activity Improves Muscle Composition in Mobility-Limited Older Adults, The VIVE2 Study: A Randomized, Double-Blind, Placebo-Controlled Trial

(2017) Davis A Englund et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Calorie Restriction-induced Weight Loss and Exercise Have Differential Effects on Skeletal Muscle Mitochondria Despite Similar Effects on Insulin Sensitivity

(2017) Elizaveta V Menshikova et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

High-Protein Foods and Physical Activity Protect Against Age-Related Muscle Loss and Functional Decline

(2017) M Loring Bradlee et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Cellular Senescence Biomarker p16INK4a+ Cell Burden in Thigh Adipose is Associated With Poor Physical Function in Older Women

(2017) Jamie N Justice et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Loss of adult skeletal muscle stem cells drives age-related neuromuscular junction degeneration

(2017) Wenxuan Liu et al.   eLife

Cellular Senescence: A Translational Perspective

(2017) James L. Kirkland et al.   EBioMedicine

Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle

(2017) Zhe Song et al.   Scientific Reports

Blunted angiogenesis and hypertrophy are associated with increased fatigue resistance and unchanged aerobic capacity in old overloaded mouse muscle

(2016) Sam B. Ballak et al.   AGE

Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice

(2016) Carolyn M. Roos et al.   AGING CELL

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors

(2016) Yi Zhu et al.   AGING CELL

Age-related deficits in skeletal muscle recovery following disuse are associated with neuromuscular junction instability and ER stress, not impaired protein synthesis

(2016) Leslie M. Baehr et al.   Aging-US

Proteome-wide muscle protein fractional synthesis rates predict muscle mass gain in response to a selective androgen receptor modulator in rats

(2016) Mahalakshmi Shankaran et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Diminished anabolic signaling response to insulin induced by intramuscular lipid accumulation is associated with inflammation in aging but not obesity

(2016) Donato A. Rivas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Mitochondrial quality control: Cell-type-dependent responses to pathological mutant mitochondrial DNA

(2016) Adriana Malena et al.   Autophagy

Coenzyme Q biosynthesis in health and disease

(2016) Manuel Jesús Acosta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Physical activity in older age: perspectives for healthy ageing and frailty

(2016) Jamie S. McPhee et al.   BIOGERONTOLOGY

A review of the assessment and prevalence of sedentarism in older adults, its physiology/health impact and non-exercise mobility counter-measures

(2016) Jorgen A. Wullems et al.   BIOGERONTOLOGY

Age-related morphological regression of myelinated fibers and capillary architecture of distal peripheral nerves in rats

(2016) Masahiro Sakita et al.   BMC NEUROSCIENCE

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

(2016) Kathryn F. Mills et al.   Cell Metabolism

Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease

(2016) Marissa J. Schafer et al.   Cell Metabolism

Cellular dynamics of regeneration reveals role of two distinct Pax7 stem cell populations in larval zebrafish muscle repair

(2016) Tapan G. Pipalia et al.   Disease Models & Mechanisms

Mfn2 deficiency links age‐related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway

(2016) David Sebastián et al.   EMBO JOURNAL

The effects of resveratrol on aging vessels

(2016) Miguel Diaz et al.   EXPERIMENTAL GERONTOLOGY

Circadian clocks govern calorie restriction–mediated life span extension through BMAL1- and IGF-1-dependent mechanisms

(2016) Sonal A. Patel et al.   FASEB JOURNAL

What Makes a 97-Year-Old Man Cycle 5,000 km a Year?

(2016) Sulin Cheng et al.   GERONTOLOGY

Testosterone Deficiency and Testosterone Treatment in Older Men

(2016) Farid Saad et al.   GERONTOLOGY

High mTORC1 signaling is maintained, while protein degradation pathways are perturbed in old murine skeletal muscles in the fasted state

(2016) Zoe White et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis

(2016) Brian T. O’Neill et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechano-signalling pathways in an experimental intensive critical illness myopathy model

(2016) Rebeca Corpeno Kalamgi et al.   JOURNAL OF PHYSIOLOGY-LONDON

FoxO-dependent atrogenes vary among catabolic conditions and play a key role in muscle atrophy induced by hindlimb suspension

(2016) Lorenza Brocca et al.   JOURNAL OF PHYSIOLOGY-LONDON

Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians

(2016) Sally Spendiff et al.   JOURNAL OF PHYSIOLOGY-LONDON

The ageing neuromuscular system and sarcopenia: a mitochondrial perspective

(2016) Karolina A. Rygiel et al.   JOURNAL OF PHYSIOLOGY-LONDON

Frameworks for Proof-of-Concept Clinical Trials of Interventions That Target Fundamental Aging Processes

(2016) Jamie Justice et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Regulation of SIRT1 in aging: Roles in mitochondrial function and biogenesis

(2016) Yujia Yuan et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Resistance Training Increases Skeletal Muscle Capillarization in Healthy Older Men

(2016) LEX B. VERDIJK et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Reactive oxygen species in sarcopenia: Should we focus on excess oxidative damage or defective redox signalling?

(2016) Malcolm J. Jackson   MOLECULAR ASPECTS OF MEDICINE

Mutations in TFAM, encoding mitochondrial transcription factor A, cause neonatal liver failure associated with mtDNA depletion

(2016) Ashlee R. Stiles et al.   MOLECULAR GENETICS AND METABOLISM

Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice

(2016) W. P. Vermeij et al.   NATURE

Evidence for a limit to human lifespan

(2016) Xiao Dong et al.   NATURE

Molecular circuitry of stem cell fate in skeletal muscle regeneration, ageing and disease

(2016) Albert E. Almada et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial dysfunction in inherited renal disease and acute kidney injury

(2016) Francesco Emma et al.   Nature Reviews Nephrology

Neuregulin1 displayed on motor axons regulates terminal Schwann cell-mediated synapse elimination at developing neuromuscular junctions

(2016) Young il Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Cristae: Where Beauty Meets Functionality

(2016) Sara Cogliati et al.   TRENDS IN BIOCHEMICAL SCIENCES

A Novel Striated Muscle-Specific Myosin-Blocking Drug for the Study of Neuromuscular Physiology

(2016) Dante J. Heredia et al.   Frontiers in Cellular Neuroscience

Long-Term Calorie Restriction Enhances Cellular Quality-Control Processes in Human Skeletal Muscle

(2016) Ling Yang et al.   Cell Reports

Age-Related and Heteroplasmy-Related Variation in Human mtDNA Copy Number

(2016) Manja Wachsmuth et al.   PLoS Genetics

Enhanced exercise and regenerative capacity in a mouse model that violates size constraints of oxidative muscle fibres

(2016) Saleh Omairi et al.   eLife

The Human Skeletal Muscle Proteome Project: a reappraisal of the current literature

(2016) Marta Gonzalez-Freire et al.   Journal of Cachexia Sarcopenia and Muscle

Skeletal muscle satellite cells are located at a closer proximity to capillaries in healthy young compared with older men

(2016) Joshua P Nederveen et al.   Journal of Cachexia Sarcopenia and Muscle

Muscle fibre capillarization is a critical factor in muscle fibre hypertrophy during resistance exercise training in older men

(2016) Tim Snijders et al.   Journal of Cachexia Sarcopenia and Muscle

Mechanical Signaling in the Pathophysiology of Critical Illness Myopathy

(2016) Rebeca C. Kalamgi et al.   Frontiers in Physiology

Targeting Heat Shock Proteins Mitigates Ventilator Induced Diaphragm Muscle Dysfunction in an Age-Dependent Manner

(2016) Hannah Ogilvie et al.   Frontiers in Physiology

Mitochondrial Quality Control and Muscle Mass Maintenance

(2016) Vanina Romanello et al.   Frontiers in Physiology

Voluntary resistance wheel exercise from mid-life prevents sarcopenia and increases markers of mitochondrial function and autophagy in muscles of old male and female C57BL/6J mice

(2016) Zoe White et al.   Skeletal Muscle

Age-related fragmentation of the motor endplate is not associated with impaired neuromuscular transmission in the mouse diaphragm

(2016) Silvia Willadt et al.   Scientific Reports

Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice

(2016) Hiroshi Nishimune et al.   Scientific Reports

Effects of testosterone on lean mass gain in elderly men: systematic review with meta-analysis of controlled and randomized studies

(2015) Walter Krause Neto et al.   AGE

Aberrant post-translational modifications compromise human myosin motor function in old age

(2015) Meishan Li et al.   AGING CELL

The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

(2015) Yi Zhu et al.   AGING CELL

CODAS Syndrome Is Associated with Mutations of LONP1, Encoding Mitochondrial AAA+ Lon Protease

(2015) Kevin A. Strauss et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Transcriptional and epigenetic regulation of autophagy in aging

(2015) Louis R Lapierre et al.   Autophagy

Transmitochondrial mito-miceΔ and mtDNA mutator mice, but not aged mice, share the same spectrum of musculoskeletal disorders

(2015) Takayuki Mito et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Emerging concepts in the therapy of mitochondrial disease

(2015) Carlo Viscomi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Changes to both cardiac metabolism and performance accompany acute reductions in functional capillary supply

(2015) David Hauton et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Muscle-specificity of age-related changes in markers of autophagy and sphingolipid metabolism

(2015) David W. Russ et al.   BIOGERONTOLOGY

The impact of obesity on skeletal muscle strength and structure through adolescence to old age

(2015) D. J. Tomlinson et al.   BIOGERONTOLOGY

Finite mixture clustering of human tissues with different levels of IGF-1 splice variants mRNA transcripts

(2015) Michele Pelosi et al.   BMC BIOINFORMATICS

The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage

(2015) Tatiana Varanita et al.   Cell Metabolism

Opa1 Overexpression Ameliorates the Phenotype of Two Mitochondrial Disease Mouse Models

(2015) Gabriele Civiletto et al.   Cell Metabolism

GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration

(2015) Marc A. Egerman et al.   Cell Metabolism

Circulating Growth Differentiation Factor 11/8 Levels Decline With AgeNovelty and Significance

(2015) Tommaso Poggioli et al.   CIRCULATION RESEARCH

Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity

(2015) Allyson K. Palmer et al.   DIABETES

Primary coenzyme Q10 deficiency presenting as fatal neonatal multiorgan failure

(2015) Maria Andrea Desbats et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Age-Associated Power Decline from Running, Jumping, and Throwing Male Masters World Records

(2015) Paolo Gava et al.   EXPERIMENTAL AGING RESEARCH

Blunted hypertrophic response in old mouse muscle is associated with a lower satellite cell density and is not alleviated by resveratrol

(2015) Sam B. Ballak et al.   EXPERIMENTAL GERONTOLOGY

Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women

(2015) Melissa M. Markofski et al.   EXPERIMENTAL GERONTOLOGY

Exercise training reverses aging-induced impairment of myogenic constriction in skeletal muscle arterioles

(2015) Payal Ghosh et al.   JOURNAL OF APPLIED PHYSIOLOGY

The Calcium-binding Proteins S100A8 and S100A9 Initiate the Early Inflammatory Program in Injured Peripheral Nerves

(2015) Andrei V. Chernov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Weekly Versus Monthly Testosterone Administration on Fast and Slow Skeletal Muscle Fibers in Older Adult Males

(2015) Robert H. Fitts et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Essential role for autophagy in life span extension

(2015) Frank Madeo et al.   JOURNAL OF CLINICAL INVESTIGATION

Local capillary supply in muscle is not determined by local oxidative capacity

(2015) A. Bosutti et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Heterogeneous ageing of skeletal muscle microvascular function

(2015) Judy M. Muller-Delp   JOURNAL OF PHYSIOLOGY-LONDON

Towards a better understanding of the role played by mitochondrial dynamics and morphology in skeletal muscle atrophy

(2015) Jean-Philippe Leduc-Gaudet et al.   JOURNAL OF PHYSIOLOGY-LONDON

Increased muscle blood supply and transendothelial nutrient and insulin transport induced by food intake and exercise: effect of obesity and ageing

(2015) Anton J. M. Wagenmakers et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mitochondrial Aging and Physical Decline: Insights From Three Generations of Women

(2015) Sadie L. Hebert et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Muscle-Derived Extracellular Signal-Regulated Kinases 1 and 2 Are Required for the Maintenance of Adult Myofibers and Their Neuromuscular Junctions

(2015) Bonnie Seaberg et al.   MOLECULAR AND CELLULAR BIOLOGY

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

(2015) Remi-Martin Laberge et al.   NATURE CELL BIOLOGY

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

(2015) Jianhui Chang et al.   NATURE MEDICINE

The HMGB1 signaling pathway activates the inflammatory response in Schwann cells

(2015) Yong-jun Wang et al.   Neural Regeneration Research

Mechanisms Regulating Neuromuscular Junction Development and Function and Causes of Muscle Wasting

(2015) Lionel A. Tintignac et al.   PHYSIOLOGICAL REVIEWS

JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age

(2015) Ming Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial dysfunction and longevity in animals: Untangling the knot

(2015) Y. Wang et al.   SCIENCE

Muscle-specific Drp1 overexpression impairs skeletal muscle growth via translational attenuation

(2015) T Touvier et al.   Cell Death & Disease

Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy

(2015) Giulia Milan et al.   Nature Communications

Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis

(2015) Ying Wang et al.   Nature Communications

Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice

(2015) Jean-Philippe Leduc-Gaudet et al.   Oncotarget

The Mitochondrial Calcium Uniporter Controls Skeletal Muscle Trophism In Vivo

(2015) Cristina Mammucari et al.   Cell Reports

Targeting senescent cells enhances adipogenesis and metabolic function in old age

(2015) Ming Xu et al.   eLife

Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay

(2015) Melissa A Hausburg et al.   eLife

p62/SQSTM1 but not LC3 is accumulated in sarcopenic muscle of mice

(2015) Kunihiro Sakuma et al.   Journal of Cachexia Sarcopenia and Muscle

Behavioural changes are a major contributing factor in the reduction of sarcopenia in caloric-restricted ageing mice

(2015) Klaske van Norren et al.   Journal of Cachexia Sarcopenia and Muscle

Myostatin antibody (LY2495655) in older weak fallers: a proof-of-concept, randomised, phase 2 trial

(2015) Clemens Becker et al.   Lancet Diabetes & Endocrinology

Oxidative proteome alterations during skeletal muscle ageing

(2015) Sofia Lourenço dos Santos et al.   Redox Biology

The ins and outs of muscle stem cell aging

(2015) Andrew S. Brack et al.   Skeletal Muscle

PGC-1α modulates denervation-induced mitophagy in skeletal muscle

(2015) Anna Vainshtein et al.   Skeletal Muscle

Pyrroloquinoline Quinone Resists Denervation-Induced Skeletal Muscle Atrophy by Activating PGC-1α and Integrating Mitochondrial Electron Transport Chain Complexes

(2015) Yung-Ting Kuo et al.   PLoS One

Aging related changes in determinants of muscle force generating capacity: A comparison of muscle aging in men and male rodents

(2014) Sam B. Ballak et al.   AGEING RESEARCH REVIEWS

Hormone replacement therapy enhances IGF-1 signaling in skeletal muscle by diminishing miR-182 and miR-223 expressions: a study on postmenopausal monozygotic twin pairs

(2014) Fabiola Olivieri et al.   AGING CELL

Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan

(2014) Dudley W. Lamming et al.   AGING CELL

Resveratrol modulates the angiogenic response to exercise training in skeletal muscles of aged men

(2014) Lasse Gliemann et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Autophagy is not required to sustain exercise and PRKAA1/AMPK activity but is important to prevent mitochondrial damage during physical activity

(2014) Francesca Lo Verso et al.   Autophagy

NAD+-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease

(2014) Raffaele Cerutti et al.   Cell Metabolism

Dissociation of Pentameric to Monomeric C-Reactive Protein Localizes and Aggravates Inflammation

(2014) Jan R. Thiele et al.   CIRCULATION

Relation between muscle mass, motor units and type of training in master athletes

(2014) Michael Drey et al.   CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING

Cellular senescence and the senescent secretory phenotype in age-related chronic diseases

(2014) Yi Zhu et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Aging impairs the recovery in mechanical muscle function following 4days of disuse

(2014) L.G. Hvid et al.   EXPERIMENTAL GERONTOLOGY

Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice

(2014) Jill E. Kolesar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Innovating Aging: Promises and Pitfalls on the Road to Life Extension

(2014) Jan Vijg et al.   GERONTOLOGY

Role of PGC-1a in Sarcopenia: Etiology and Potential Intervention - A Mini-Review

(2014) Li Li Ji et al.   GERONTOLOGY

Skeletal muscle capillary density and microvascular function are compromised with aging and type 2 diabetes

(2014) Bart B. L. Groen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Glucose uptake in brown fat cells is dependent on mTOR complex 2–promoted GLUT1 translocation

(2014) Jessica M. Olsen et al.   JOURNAL OF CELL BIOLOGY

HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy

(2014) A. W. Beharry et al.   JOURNAL OF CELL SCIENCE

Molecules Involved in the Crosstalk Between Immune- and Peripheral Nerve Schwann Cells

(2014) Nevena Tzekova et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Atrogin-1 deficiency promotes cardiomyopathy and premature death via impaired autophagy

(2014) Tania Zaglia et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic bases and clinical manifestations of coenzyme Q10 (CoQ10) deficiency

(2014) Maria Andrea Desbats et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Long-Term High-Level Exercise Promotes Muscle Reinnervation With Age

(2014) Simone Mosole et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

LRP4 Is Critical for Neuromuscular Junction Maintenance

(2014) A. Barik et al.   JOURNAL OF NEUROSCIENCE

Terminal Schwann Cells Participate in Neuromuscular Synapse Remodeling during Reinnervation following Nerve Injury

(2014) H. Kang et al.   JOURNAL OF NEUROSCIENCE

Protein Carbonylation and Heat Shock Proteins in Human Skeletal Muscle: Relationships to Age and Sarcopenia

(2014) M. R. Beltran Valls et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Downregulation of E3 Ubiquitin Ligases and Mitophagy-Related Genes in Skeletal Muscle of Physically Inactive, Frail Older Women: A Cross-Sectional Comparison

(2014) M. J. Drummond et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Inhibition of JAK-STAT signaling stimulates adult satellite cell function

(2014) Feodor D Price et al.   NATURE MEDICINE

STAT3 signaling controls satellite cell expansion and skeletal muscle repair

(2014) Matthew Timothy Tierney et al.   NATURE MEDICINE

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

(2014) Benjamin D Cosgrove et al.   NATURE MEDICINE

p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice

(2014) Jennifer D Bernet et al.   NATURE MEDICINE

The Relationship between Muscle Fiber Type-Specific PGC-1α Content and Mitochondrial Content Varies between Rodent Models and Humans

(2014) Gilles Gouspillou et al.   PLoS One

The Scientific Quest for Lasting Youth: Prospects for Curing Aging

(2014) João Pedro de Magalhães   REJUVENATION RESEARCH

TGFβ and BMP signaling in skeletal muscle: potential significance for muscle-related disease

(2014) Roberta Sartori et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Autophagy Impairment in Muscle Induces Neuromuscular Junction Degeneration and Precocious Aging

(2014) Silvia Carnio et al.   Cell Reports

Qualitative alteration of peripheral motor system begins prior to appearance of typical sarcopenia syndrome in middle-aged rats

(2014) Tetsuro Tamaki et al.   Frontiers in Aging Neuroscience

Mitochondrial Involvement and Impact in Aging Skeletal Muscle

(2014) Russell T. Hepple   Frontiers in Aging Neuroscience

FOXO3 Promotes Quiescence in Adult Muscle Stem Cells during the Process of Self-Renewal

(2014) Suchitra D. Gopinath et al.   Stem Cell Reports

Maintenance of muscle mass and load-induced growth in Muscle RING Finger 1 null mice with age

(2013) Darren T. Hwee et al.   AGING CELL

Glycolytic fast-twitch muscle fiber restoration counters adverse age-related changes in body composition and metabolism

(2013) Yuichi Akasaki et al.   AGING CELL

Apoptosis in capillary endothelial cells in ageing skeletal muscle

(2013) Huijuan Wang et al.   AGING CELL

Sex hormones and skeletal muscle weakness

(2013) Sarianna Sipilä et al.   BIOGERONTOLOGY

Detection of an aging-related increase in advanced glycation end products in fast- and slow-twitch skeletal muscles in the rat

(2013) B. Ramamurthy et al.   BIOGERONTOLOGY

Signalling pathways regulating muscle mass in ageing skeletal muscle. The role of the IGF1-Akt-mTOR-FoxO pathway

(2013) M. Sandri et al.   BIOGERONTOLOGY

The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo-controlled, Phase III study in patients with myelofibrosis

(2013) Srdan Verstovsek et al.   BRITISH JOURNAL OF HAEMATOLOGY

Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

(2013) Sara Cogliati et al.   CELL

The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

(2013) Laurent Mouchiroud et al.   CELL

Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy

(2013) Francesco S. Loffredo et al.   CELL

Myf5-Positive Satellite Cells Contribute to Pax7-Dependent Long-Term Maintenance of Adult Muscle Stem Cells

(2013) Stefan Günther et al.   Cell Stem Cell

Mechanical Ventilation-Induced Reverse-Triggered Breaths

(2013) Evangelia Akoumianaki et al.   CHEST

Signaling pathways controlling skeletal muscle mass

(2013) Marc A. Egerman et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans

(2013) Gilles Gouspillou et al.   FASEB JOURNAL

Mechanisms regulating skeletal muscle growth and atrophy

(2013) Stefano Schiaffino et al.   FEBS Journal

Mitochondrial dysfunction and sarcopenia of aging: From signaling pathways to clinical trials

(2013) Emanuele Marzetti et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Skeletal muscle excitation–contraction coupling: Who are the dancing partners?

(2013) Robyn T. Rebbeck et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Age and exercise training alter signaling through reactive oxygen species in the endothelium of skeletal muscle arterioles

(2013) Amy L. Sindler et al.   JOURNAL OF APPLIED PHYSIOLOGY

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass

(2013) Catherine E. Winbanks et al.   JOURNAL OF CELL BIOLOGY

Regulation of mTORC1 and its impact on gene expression at a glance

(2013) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Enhanced autophagy ameliorates cardiac proteinopathy

(2013) Md. Shenuarin Bhuiyan et al.   JOURNAL OF CLINICAL INVESTIGATION

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

(2013) Tamara Tchkonia et al.   JOURNAL OF CLINICAL INVESTIGATION

WldS and PGC-1  Regulate Mitochondrial Transport and Oxidation State after Axonal Injury

(2013) K. C. O'Donnell et al.   JOURNAL OF NEUROSCIENCE

Segmentation of the mouse fourth deep lumbrical muscle connectome reveals concentric organisation of motor units

(2013) Theodore C. Hirst et al.   JOURNAL OF PHYSIOLOGY-LONDON

Hormone replacement therapy improves contractile function and myonuclear organization of single muscle fibres from postmenopausal monozygotic female twin pairs

(2013) Rizwan Qaisar et al.   JOURNAL OF PHYSIOLOGY-LONDON

Nonsteroidal Anti-Inflammatory Drug (NSAID) Use and Sarcopenia in Older People: Results From the ilSIRENTE Study

(2013) Francesco Landi et al.   Journal of the American Medical Directors Association

Proinflammatory Cytokines, Aging, and Age-Related Diseases

(2013) Martin Michaud et al.   Journal of the American Medical Directors Association

Mitonuclear protein imbalance as a conserved longevity mechanism

(2013) Riekelt H. Houtkooper et al.   NATURE

BMP signaling controls muscle mass

(2013) Roberta Sartori et al.   NATURE GENETICS

The clinical maze of mitochondrial neurology

(2013) Salvatore DiMauro et al.   Nature Reviews Neurology

Satellite Cells and the Muscle Stem Cell Niche

(2013) Hang Yin et al.   PHYSIOLOGICAL REVIEWS

Dysregulation of Mitochondrial Quality Control Processes Contribute to Sarcopenia in a Mouse Model of Premature Aging

(2013) Anna-Maria Joseph et al.   PLoS One

Optogenetic Control of Targeted Peripheral Axons in Freely Moving Animals

(2013) Chris Towne et al.   PLoS One

Pax7 is critical for the normal function of satellite cells in adult skeletal muscle

(2013) J. von Maltzahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear positioning in muscle development and disease

(2013) Eric S. Folker et al.   Frontiers in Physiology

The interactions of oxidative stress and inflammation with vascular dysfunction in ageing: the vascular health triad

(2012) Alex J. Wadley et al.   AGE

Nitric oxide and voluntary exercise together promote quadriceps hypertrophy and increase vascular density in female 18-mo-old mice

(2012) Jeff R. S. Leiter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Molecular mechanism of actin-myosin motor in muscle

(2012) N. A. Koubassova et al.   BIOCHEMISTRY-MOSCOW

Aging, Rejuvenation, and Epigenetic Reprogramming: Resetting the Aging Clock

(2012) Thomas A. Rando et al.   CELL

RETRACTED: The Ubiquitin Ligase Mul1 Induces Mitophagy in Skeletal Muscle in Response to Muscle-Wasting Stimuli

(2012) Sudarsanareddy Lokireddy et al.   Cell Metabolism

Chronic Caloric Restriction Preserves Mitochondrial Function in Senescence without Increasing Mitochondrial Biogenesis

(2012) Ian R. Lanza et al.   Cell Metabolism

Coordination of Satellite Cell Activation and Self-Renewal by Par-Complex-Dependent Asymmetric Activation of p38α/β MAPK

(2012) Andrew Troy et al.   Cell Stem Cell

Carm1 Regulates Pax7 Transcriptional Activity through MLL1/2 Recruitment during Asymmetric Satellite Stem Cell Divisions

(2012) Yoh-ichi Kawabe et al.   Cell Stem Cell

Pax3/7BP Is a Pax7- and Pax3-Binding Protein that Regulates the Proliferation of Muscle Precursor Cells by an Epigenetic Mechanism

(2012) Yarui Diao et al.   Cell Stem Cell

Muscle Satellite Cells Are Primed for Myogenesis but Maintain Quiescence with Sequestration of Myf5 mRNA Targeted by microRNA-31 in mRNP Granules

(2012) Colin G. Crist et al.   Cell Stem Cell

Aging and Atherosclerosis

(2012) Julie C. Wang et al.   CIRCULATION RESEARCH

A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes

(2012) Vincent Soubannier et al.   CURRENT BIOLOGY

Cellular and molecular mechanisms of muscle atrophy

(2012) P. Bonaldo et al.   Disease Models & Mechanisms

Vascular health in the ageing athlete

(2012) Allison E. DeVan et al.   EXPERIMENTAL PHYSIOLOGY

Functional Analysis of Missense Mutations ofOAT, Causing Gyrate Atrophy of Choroid and Retina

(2012) Mara Doimo et al.   HUMAN MUTATION

Overexpression of the Coq8 Kinase inSaccharomyces cerevisiae coqNull Mutants Allows for Accumulation of Diagnostic Intermediates of the Coenzyme Q6Biosynthetic Pathway

(2012) Letian X. Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects ofin vivoinjury on the neuromuscular junction in healthy and dystrophic muscles

(2012) Stephen J.P. Pratt et al.   JOURNAL OF PHYSIOLOGY-LONDON

Exercise and longevity

(2012) Vincent Gremeaux et al.   MATURITAS

Genomic and Proteomic Profiling Reveals Reduced Mitochondrial Function and Disruption of the Neuromuscular Junction Driving Rat Sarcopenia

(2012) C. Ibebunjo et al.   MOLECULAR AND CELLULAR BIOLOGY

The aged niche disrupts muscle stem cell quiescence

(2012) Joe V. Chakkalakal et al.   NATURE

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cytochrome c oxidase-intermediate fibres: Importance in understanding the pathogenesis and treatment of mitochondrial myopathy

(2012) Julie L. Murphy et al.   NEUROMUSCULAR DISORDERS

Copper and bezafibrate cooperate to rescue cytochrome c oxidase deficiency in cells of patients with sco2 mutations

(2012) Alberto Casarin et al.   Orphanet Journal of Rare Diseases

Denervation Causes Fiber Atrophy and Myosin Heavy Chain Co-Expression in Senescent Skeletal Muscle

(2012) Sharon L. Rowan et al.   PLoS One

Shared Resistance to Aging and ALS in Neuromuscular Junctions of Specific Muscles

(2012) Gregorio Valdez et al.   PLoS One

Effects of Fiber Type and Size on the Heterogeneity of Oxygen Distribution in Exercising Skeletal Muscle

(2012) Gang Liu et al.   PLoS One

PGC-1α is Dispensable for Exercise-Induced Mitochondrial Biogenesis in Skeletal Muscle

(2012) Glenn C. Rowe et al.   PLoS One

Agrin and Synaptic Laminin Are Required to Maintain Adult Neuromuscular Junctions

(2012) Melanie A. Samuel et al.   PLoS One

Reconstitution of Mitochondria Derived Vesicle Formation Demonstrates Selective Enrichment of Oxidized Cargo

(2012) Vincent Soubannier et al.   PLoS One

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

(2012) D. W. Lamming et al.   SCIENCE

Wnt signaling in myogenesis

(2012) Julia von Maltzahn et al.   TRENDS IN CELL BIOLOGY

Reversing the Outcome of Synapse Elimination at Developing Neuromuscular Junctions In Vivo: Evidence for Synaptic Competition and Its Mechanism

(2012) Stephen G. Turney et al.   PLOS BIOLOGY

There is no slowing of motility speed with increased body size in rat, human, horse and rhinoceros independent on temperature and skeletal muscle myosin isoform

(2011) M. Li et al.   Acta Physiologica

Exponential growth combined with exponential decline explains lifetime performance evolution in individual and human species

(2011) Geoffroy Berthelot et al.   AGE

Myosin light chain 3f attenuates age-induced decline in contractile velocity in MHC type II single muscle fibers

(2011) Jong-Hee Kim et al.   AGING CELL

Differential influence of peripheral and systemic sex steroids on skeletal muscle quality in pre- and postmenopausal women

(2011) Eija Pöllänen et al.   AGING CELL

Aging Causes Collateral Rarefaction and Increased Severity of Ischemic Injury in Multiple Tissues

(2011) James E. Faber et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Regulation of myogenic stem cell behaviour by vessel cells: The "ménage à trois" of satellite cells, periendothelial cells and endothelial cells

(2011) Rana Abou-Khalil et al.   CELL CYCLE

In Vivo Correction of COX Deficiency by Activation of the AMPK/PGC-1α Axis

(2011) Carlo Viscomi et al.   Cell Metabolism

Coenzyme Q deficiency in muscle

(2011) Eva Trevisson et al.   CURRENT OPINION IN NEUROLOGY

Is functional hypertrophy and specific force coupled with the addition of myonuclei at the single muscle fiber level?

(2011) Rizwan Qaisar et al.   FASEB JOURNAL

PKB signaling and atrogene expression in skeletal muscle of aged mice

(2011) Megan Gaugler et al.   JOURNAL OF APPLIED PHYSIOLOGY

Reduced TrkB expression results in precocious age-like changes in neuromuscular structure, neurotransmission, and muscle function

(2011) Scott A. Kulakowski et al.   JOURNAL OF APPLIED PHYSIOLOGY

Exercise Increases Mitochondrial PGC-1α Content and Promotes Nuclear-Mitochondrial Cross-talk to Coordinate Mitochondrial Biogenesis

(2011) Adeel Safdar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spatial constraints dictate glial territories at murine neuromuscular junctions

(2011) Monika S. Brill et al.   JOURNAL OF CELL BIOLOGY

Structural Basis for Myopathic Defects Engendered by Alterations in the Myosin Rod

(2011) Anthony Cammarato et al.   JOURNAL OF MOLECULAR BIOLOGY

Nerve Terminal Growth Remodels Neuromuscular Synapses in Mice following Regeneration of the Postsynaptic Muscle Fiber

(2011) Y. Li et al.   JOURNAL OF NEUROSCIENCE

Accelerated Age-Related Cognitive Decline and Neurodegeneration, Caused by Deficient DNA Repair

(2011) N. Z. Borgesius et al.   JOURNAL OF NEUROSCIENCE

Changes in Aging Mouse Neuromuscular Junctions Are Explained by Degeneration and Regeneration of Muscle Fiber Segments at the Synapse

(2011) Y. Li et al.   JOURNAL OF NEUROSCIENCE

Disruption of neurovascular unit prior to motor neuron degeneration in amyotrophic lateral sclerosis

(2011) Kazunori Miyazaki et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Lateral transmission of force is impaired in skeletal muscles of dystrophic mice and very old rats

(2011) Krishnan S. Ramaswamy et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mitochondria: isolation, structure and function

(2011) Martin Picard et al.   JOURNAL OF PHYSIOLOGY-LONDON

Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: underlying mechanisms

(2011) Julien Ochala et al.   JOURNAL OF PHYSIOLOGY-LONDON

Arteriolar and Venular Capillary Distribution in Skeletal Muscles of Old Rats

(2011) L. Cui et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Sarcopenia Accelerates at Advanced Ages in Fisher 344xBrown Norway Rats

(2011) E. B. Lushaj et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Serum Concentrations of Myostatin and Myostatin-Interacting Proteins Do Not Differ Between Young and Sarcopenic Elderly Men

(2011) A. Ratkevicius et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Optimization of respiratory chain enzymatic assays in muscle for the diagnosis of mitochondrial disorders

(2011) Marco Spinazzi et al.   MITOCHONDRION

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Striking Denervation of Neuromuscular Junctions without Lumbar Motoneuron Loss in Geriatric Mouse Muscle

(2011) Ruth Jinfen Chai et al.   PLoS One

PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function

(2011) F. Billia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prior poliomyelitis: an immunohistochemical study of cytoskeletal proteins and a marker for muscle fibre regeneration in relation to usage of remaining motor units

(2010) K. Borg et al.   ACTA NEUROLOGICA SCANDINAVICA

Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice

(2010) Monique C. de Waard et al.   ACTA NEUROPATHOLOGICA

Physiological factors influencing capillary growth

(2010) S. Egginton   Acta Physiologica

Inflammatory markers in population studies of aging

(2010) Tushar Singh et al.   AGEING RESEARCH REVIEWS

Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers

(2010) Martin Picard et al.   AGING CELL

Effects of aging and gender on the spatial organization of nuclei in single human skeletal muscle cells

(2010) Alexander Cristea et al.   AGING CELL

Fat tissue, aging, and cellular senescence

(2010) Tamara Tchkonia et al.   AGING CELL

The time course of myonuclear accretion during hypertrophy in young adult and older rat plantaris muscle

(2010) Sander F.T. van der Meer et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Expression of Chr9p21 genes CDKN2B (p15INK4b), CDKN2A (p16INK4a, p14ARF) and MTAP in human atherosclerotic plaque

(2010) Lesca Miriam Holdt et al.   ATHEROSCLEROSIS

Elevated satellite cell number in Duchenne muscular dystrophy

(2010) Michael Kottlors et al.   CELL AND TISSUE RESEARCH

Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity

(2010) Christoph Zechner et al.   Cell Metabolism

Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle

(2010) Carles Cantó et al.   Cell Metabolism

Mitochondrial fission and remodelling contributes to muscle atrophy

(2010) Vanina Romanello et al.   EMBO JOURNAL

Mitochondrial shape changes: orchestrating cell pathophysiology

(2010) Silvia Campello et al.   EMBO REPORTS

The muscle fiber type–fiber size paradox: hypertrophy or oxidative metabolism?

(2010) T. van Wessel et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Remodeling of the neuromuscular junction precedes sarcopenia related alterations in myofibers

(2010) Michael R. Deschenes et al.   EXPERIMENTAL GERONTOLOGY

Age-associated alterations of the neuromuscular junction

(2010) Youngmok C. Jang et al.   EXPERIMENTAL GERONTOLOGY

Experimental Physiology -Review Article: Tissue capillary supply - it's quality not quantity that counts!

(2010) Stuart Egginton et al.   EXPERIMENTAL PHYSIOLOGY

Reactive oxygen species, oxidative stress, and cell death correlate with level of CoQ10 deficiency

(2010) Catarina M. Quinzii et al.   FASEB JOURNAL

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Toll-like receptor expression in the peripheral nerve

(2010) Sofie Goethals et al.   GLIA

Effects of aging on muscle mechanical function and muscle fiber morphology during short-term immobilization and subsequent retraining

(2010) Lars Hvid et al.   JOURNAL OF APPLIED PHYSIOLOGY

Muscle Wasting in Aged, Sarcopenic Rats Is Associated with Enhanced Activity of the Ubiquitin Proteasome Pathway

(2010) Mikael Altun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

(2010) Seok Min Jin et al.   JOURNAL OF CELL BIOLOGY

Grip work estimation during sustained maximal contraction: Validity and relationship with dependency and inflammation in elderly persons

(2010) Ivan Bautmans et al.   Journal of Nutrition Health & Aging

Anti-inflammation - just another word for anti-ageing?

(2010) Bente K. Pedersen   JOURNAL OF PHYSIOLOGY-LONDON

Force-generating capacity of human myosin isoforms extracted from single muscle fibre segments

(2010) Meishan Li et al.   JOURNAL OF PHYSIOLOGY-LONDON

Physiological angiogenesis is a graded, not threshold, response

(2010) S. Egginton et al.   JOURNAL OF PHYSIOLOGY-LONDON

Effects of Testosterone on Skeletal Muscle Architecture in Intermediate-Frail and Frail Elderly Men

(2010) R. A. Atkinson et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Effects of aging and gender on muscle mass and regulation of Akt-mTOR-p70s6k related signaling in the F344BN rat model

(2010) Satyanarayana Paturi et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Life-long caloric restriction: Effect on age-related changes in motoneuron numbers, sizes and apoptotic markers

(2010) Jeremy W. Chopek et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The molecular basis by which dietary restricted feeding reduces mitochondrial reactive oxygen species generation

(2010) C.E. Ash et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Motor Unit Number Estimates in Masters Runners

(2010) GEOFFREY A. POWER et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Telomere shortening is associated to TRF1 and PARP1 overexpression in Duchenne muscular dystrophy

(2010) M’Hammed Aguennouz et al.   NEUROBIOLOGY OF AGING

Myopathies in the elderly: A hospital-based study

(2010) Andoni Echaniz-Laguna et al.   NEUROMUSCULAR DISORDERS

Effects of Aging and Exercise on Nutrition Needs of the Elderly

(2010) William J. Evans   NUTRITION REVIEWS

A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen

(2010) Jean-Philippe Coppé et al.   PLoS One

Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise

(2010) G. Valdez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myonuclei acquired by overload exercise precede hypertrophy and are not lost on detraining

(2010) J. C. Bruusgaard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of the nervous system in sarcopenia and muscle atrophy with aging: strength training as a countermeasure

(2010) P. Aagaard et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Ageing influences myonuclear domain size differently in fast and slow skeletal muscle of rats

(2009) N. E. Brooks et al.   Acta Physiologica

Association of C-reactive protein and muscle strength in the English Longitudinal Study of Ageing

(2009) Mark Hamer et al.   AGE

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

(2009) Anne Ulrike Trendelenburg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Smad2 and 3 transcription factors control muscle mass in adulthood

(2009) Roberta Sartori et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Region-specific adaptations in determinants of rat skeletal muscle oxygenation to chronic hypoxia

(2009) R. C. I. Wüst et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Alteration of mitochondrial oxidative phosphorylation in aged skeletal muscle involves modification of adenine nucleotide translocator

(2009) Gilles Gouspillou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

Skeletal Muscle Injury Versus Adaptation with Aging

(2009) Brent A. Baker et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Age-related changes of cell death pathways in rat extraocular muscle

(2009) Colleen A. McMullen et al.   EXPERIMENTAL GERONTOLOGY

Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise

(2009) Stephanie Eva Wohlgemuth et al.   EXPERIMENTAL GERONTOLOGY

Effects of aging on human skeletal muscle after immobilization and retraining

(2009) C. Suetta et al.   JOURNAL OF APPLIED PHYSIOLOGY

Time course of changes in inflammatory markers during a 6-mo exercise intervention in sedentary middle-aged men: a randomized-controlled trial

(2009) Dylan Thompson et al.   JOURNAL OF APPLIED PHYSIOLOGY

Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells

(2009) Brian Head et al.   JOURNAL OF CELL BIOLOGY

3D Visualization and Measurement of Capillaries Supplying Metabolically Different Fiber Types in the Rat Extensor Digitorum Longus Muscle During Denervation and Reinnervation

(2009) Jiîí Janáček et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Reduction of low grade inflammation restores blunting of postprandial muscle anabolism and limits sarcopenia in old rats

(2009) Isabelle Rieu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Inflammation Markers and Malnutrition as Risk Factors for Infections and Impaired Health-Related Quality of Life Among Older Nursing Home Residents

(2009) Liisa K. Kuikka et al.   Journal of the American Medical Directors Association

Myofibrillar protein and gene expression in acute quadriplegic myopathy

(2009) Holly Norman et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Higher C-Reactive Protein and Soluble Tumor Necrosis Factor Receptor Levels Are Associated With Poor Physical Function and Disability: A Cross-Sectional Analysis of a Cohort of Late Middle-Aged African Americans

(2009) M. T. Haren et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

A crucial role for adipose tissue p53 in the regulation of insulin resistance

(2009) Tohru Minamino et al.   NATURE MEDICINE

Single muscle fiber properties in aging and disuse

(2009) M. Canepari et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

The role of systemic inflammation in age-related muscle weakness and wasting

(2009) H. Degens   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Effects of combined strength and sprint training on regulation of muscle contraction at the whole-muscle and single-fibre levels in elite master sprinters

(2008) A. Cristea et al.   Acta Physiologica

The time course of denervation-induced changes is similar in soleus muscles of adult and old rats

(2008) Hans Degens et al.   Applied Physiology Nutrition and Metabolism

Proteasome activities in the rectus abdominis muscle of young and older individuals

(2008) Maurizio Bossola et al.   BIOGERONTOLOGY

Sarcoplasmic Reticulum Ca2+ Release Declines in Muscle Fibers from Aging Mice

(2008) Ramón Jiménez-Moreno et al.   BIOPHYSICAL JOURNAL

Prolonged acute mechanical ventilation and hospital bed utilization in 2020 in the United States: implications for budgets, plant and personnel planning

(2008) Marya D Zilberberg et al.   BMC HEALTH SERVICES RESEARCH

Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network

(2008) Thomas Kuilman et al.   CELL

Nonsteroidal Anti-Inflammatory Drugs in Experimental Parkinsonian Models and Parkinsons Disease

(2008) Masato Asanuma et al.   CURRENT PHARMACEUTICAL DESIGN

Endurance Exercise as a Countermeasure for Aging

(2008) I. R. Lanza et al.   DIABETES

Myonuclear domain size and myosin isoform expression in muscle fibres from mammals representing a 100 000-fold difference in body size

(2008) Jing-Xia Liu et al.   EXPERIMENTAL PHYSIOLOGY

Sex differences in contractile properties and fatigue resistance of human skeletal muscle

(2008) Rob C. I. Wüst et al.   EXPERIMENTAL PHYSIOLOGY

A functionally dominant mitochondrial DNA mutation

(2008) S. Sacconi et al.   HUMAN MOLECULAR GENETICS

The Skeletal L-type Ca2+Current Is a Major Contributor to Excitation-coupled Ca2+entry

(2008) Roger A. Bannister et al.   JOURNAL OF GENERAL PHYSIOLOGY

PPAR: a therapeutic target in Parkinsons disease

(2008) Rajnish K. Chaturvedi et al.   JOURNAL OF NEUROCHEMISTRY

The danger of weight loss in the elderly

(2008) S. L. Miller et al.   Journal of Nutrition Health & Aging

Respiratory Active Mitochondrial Supercomplexes

(2008) Rebeca Acín-Pérez et al.   MOLECULAR CELL

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

(2008) Zoltan Arany et al.   NATURE

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY

Mitochondrial function and apoptotic susceptibility in aging skeletal muscle

(2007) Béatrice Chabi et al.   AGING CELL

OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes

(2007) P. Amati-Bonneau et al.   BRAIN

Aging alters gene expression of growth and remodeling factors in human skeletal muscle both at rest and in response to acute resistance exercise

(2007) Richard A. Dennis et al.   PHYSIOLOGICAL GENOMICS