Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans

Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

(2016) Angela V. Hafner et al.   Aging-US

Mitochondrial energetics is impairedin vivoin aged skeletal muscle

(2013) Gilles Gouspillou et al.   AGING CELL

Protective role of PARK2/Parkin in sepsis-induced cardiac contractile and mitochondrial dysfunction

(2013) Jérôme Piquereau et al.   Autophagy

Markers of Human Skeletal Muscle Mitochondrial Biogenesis and Quality Control: Effects of Age and Aerobic Exercise Training

(2013) Adam R. Konopka et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Dysregulation of Mitochondrial Quality Control Processes Contribute to Sarcopenia in a Mouse Model of Premature Aging

(2013) Anna-Maria Joseph et al.   PLoS One

Dimers of mitochondrial ATP synthase form the permeability transition pore

(2013) V. Giorgio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals

(2012) Anna-Maria Joseph et al.   AGING CELL

Physiological Roles of the Permeability Transition Pore

(2012) Catherine Brenner et al.   CIRCULATION RESEARCH

Severe atrophy of slow myofibers in aging muscle is concealed by myosin heavy chain co-expression

(2012) Fennigje M. Purves-Smith et al.   EXPERIMENTAL GERONTOLOGY

Voltage-dependent Anion Channels (VDACs) Recruit Parkin to Defective Mitochondria to Promote Mitochondrial Autophagy

(2012) Yu Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Skeletal Muscle Apoptotic Signaling Predicts Thigh Muscle Volume and Gait Speed in Community-Dwelling Older Persons: An Exploratory Study

(2012) Emanuele Marzetti et al.   PLoS One

Denervation Causes Fiber Atrophy and Myosin Heavy Chain Co-Expression in Senescent Skeletal Muscle

(2012) Sharon L. Rowan et al.   PLoS One

Alterations in intrinsic mitochondrial function with aging are fiber type-specific and do not explain differential atrophy between muscles

(2011) Martin Picard et al.   AGING CELL

Mitochondrial functional specialization in glycolytic and oxidative muscle fibers: tailoring the organelle for optimal function

(2011) Martin Picard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Reduction in Reactive Oxygen Species Production by Mitochondria From Elderly Subjects With Normal and Impaired Glucose Tolerance

(2011) S. Ghosh et al.   DIABETES

Mitochondria: isolation, structure and function

(2011) Martin Picard et al.   JOURNAL OF PHYSIOLOGY-LONDON

Quantity and Quality of Exercise for Developing and Maintaining Cardiorespiratory, Musculoskeletal, and Neuromotor Fitness in Apparently Healthy Adults

(2011) Carol Ewing Garber et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore

(2011) Pinadda Varanyuwatana et al.   MITOCHONDRION

Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers

(2010) Martin Picard et al.   AGING CELL

The Interplay Between Mitochondrial Dynamics and Mitophagy

(2010) Gilad Twig et al.   ANTIOXIDANTS & REDOX SIGNALING

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Aberrant Mitochondrial Homeostasis in the Skeletal Muscle of Sedentary Older Adults

(2010) Adeel Safdar et al.   PLoS One

Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice

(2010) Asimina Hiona et al.   PLoS One

Mitochondrial Turnover and Aging of Long-Lived Postmitotic Cells: The Mitochondrial–Lysosomal Axis Theory of Aging

(2009) Alexei Terman et al.   ANTIOXIDANTS & REDOX SIGNALING

Alteration of mitochondrial oxidative phosphorylation in aged skeletal muscle involves modification of adenine nucleotide translocator

(2009) Gilles Gouspillou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial death effectors: Relevance to sarcopenia and disuse muscle atrophy

(2009) Emanuele Marzetti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Age, Obesity, and Sex Effects on Insulin Sensitivity and Skeletal Muscle Mitochondrial Function

(2009) H. Karakelides et al.   DIABETES

Subjects With Early-Onset Type 2 Diabetes Show Defective Activation of the Skeletal Muscle PGC-1 /Mitofusin-2 Regulatory Pathway in Response to Physical Activity

(2009) M. I. Hernandez-Alvarez et al.   DIABETES CARE

What is the mitochondrial permeability transition pore?

(2009) Andrew P. Halestrap   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Resistance to Ca2+-induced opening of the permeability transition pore differs in mitochondria from glycolytic and oxidative muscles

(2008) Martin Picard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Age-related activation of mitochondrial caspase-independent apoptotic signaling in rat gastrocnemius muscle

(2008) Emanuele Marzetti et al.   MECHANISMS OF AGEING AND DEVELOPMENT

DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice

(2008) Marc Vermulst et al.   NATURE GENETICS

Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells

(2008) Andrey V Kuznetsov et al.   Nature Protocols

Mitochondrial function and apoptotic susceptibility in aging skeletal muscle

(2007) Béatrice Chabi et al.   AGING CELL

Giant mitochondria do not fuse and exchange their contents with normal mitochondria

(2007) Marian Navratil et al.   EXPERIMENTAL CELL RESEARCH