Atrogin-1 deficiency promotes cardiomyopathy and premature death via impaired autophagy

Roles of ESCRT in autophagy-associated neurodegeneration

(2014) Jin-A Lee et al.   Autophagy

A novel link between autophagy and the ubiquitin-proteasome system

(2014) Viktor I. Korolchuk et al.   Autophagy

Identification of properties important to protein aggregation using feature selection

(2013) Yaping Fang et al.   BMC BIOINFORMATICS

Enhanced autophagy ameliorates cardiac proteinopathy

(2013) Md. Shenuarin Bhuiyan et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of Ubiquitin Ligases and the Proteasome in Oncogenesis: Novel Targets for Anticancer Therapies

(2013) Lindsey N. Micel et al.   JOURNAL OF CLINICAL ONCOLOGY

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Crosstalk between the ubiquitin–proteasome system and autophagy in a human cellular model of Alzheimer's disease

(2012) Valentina Cecarini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cardiac sympathetic neurons provide trophic signal to the heart via β2-adrenoceptor-dependent regulation of proteolysis

(2012) Tania Zaglia et al.   CARDIOVASCULAR RESEARCH

Furthering the link between the sarcomere and primary cardiomyopathies: Restrictive cardiomyopathy associated with multiple mutations in genes previously associated with hypertrophic or dilated cardiomyopathy

(2011) Colleen Caleshu et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Taking pressure off the heart: the ins and outs of atrophic remodelling

(2011) K. K. Baskin et al.   CARDIOVASCULAR RESEARCH

Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy

(2011) E. D. Abel et al.   CARDIOVASCULAR RESEARCH

Endogenous Muscle Atrophy F-Box Mediates Pressure Overload–Induced Cardiac Hypertrophy Through Regulation of Nuclear Factor-κB

(2011) Soichiro Usui et al.   CIRCULATION RESEARCH

Atg7 Induces Basal Autophagy and Rescues Autophagic Deficiency in CryAB R120G Cardiomyocytes

(2011) J. Scott Pattison et al.   CIRCULATION RESEARCH

The ubiquitin–proteasome system in cardiomyopathies

(2011) Saskia Schlossarek et al.   CURRENT OPINION IN CARDIOLOGY

Tearin' Up My Heart: Proteolysis in the Cardiac Sarcomere

(2011) Andrea L. Portbury et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiac myosin-binding protein C in hypertrophic cardiomyopathy: Mechanisms and therapeutic opportunities

(2011) Saskia Schlossarek et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Athlete's Heart vs. the Failing Heart: Can Signaling Explain the Two Distinct Outcomes?

(2011) Kate L. Weeks et al.   PHYSIOLOGY

Macroautophagy Is Regulated by the UPR–Mediator CHOP and Accentuates the Phenotype of SBMA Mice

(2011) Zhigang Yu et al.   PLoS Genetics

Cardiotoxicity of the Anticancer Therapeutic Agent Bortezomib

(2010) Dominika Nowis et al.   AMERICAN JOURNAL OF PATHOLOGY

A reporter cell system to monitor autophagy based on p62/SQSTM1

(2010) Kenneth Bowitz Larsen et al.   Autophagy

VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD

(2010) Emilie Tresse et al.   Autophagy

Inhibition of autophagy in the heart induces age-related cardiomyopathy

(2010) Manabu Taneike et al.   Autophagy

The role of ESCRT proteins in fusion events involving lysosomes, endosomes and autophagosomes: Figure 1

(2010) Daniel Metcalf et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Molecular Pathways Underlying Cardiac Remodeling During Pathophysiological Stimulation

(2010) Izhak Kehat et al.   CIRCULATION

Ubiquitin Proteasome Dysfunction in Human Hypertrophic and Dilated Cardiomyopathies

(2010) Jaime M. Predmore et al.   CIRCULATION

Sent to Destroy

(2010) Monte S. Willis et al.   CIRCULATION RESEARCH

Autophagy is defective in collagen VI muscular dystrophies and its reactivation rescues myofiber degeneration

(2010) Paolo Grumati et al.   NATURE MEDICINE

Autophagy defects contribute to neurodegeneration induced by dysfunctional ESCRT-III

(2009) Jin-A Lee et al.   Autophagy

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems

(2009) Viktor I. Korolchuk et al.   FEBS LETTERS

Calcineurin protects the heart in a murine model of dilated cardiomyopathy

(2009) Joerg Heineke et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

(2009) Camilla Raiborg et al.   NATURE

Acute severe cardiac failure in a myeloma patient due to proteasome inhibitor bortezomib

(2008) Abdullah Hacihanefioglu et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Lysosomal myopathies: An excessive build-up in autophagosomes is too much to handle

(2008) May Christine Malicdan et al.   NEUROMUSCULAR DISORDERS