Targeting senescent cells enhances adipogenesis and metabolic function in old age
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting senescent cells enhances adipogenesis and metabolic function in old age
Authors
Keywords
-
Journal
eLife
Volume 4, Issue -, Pages -
Publisher
eLife Sciences Organisation, Ltd.
Online
2015-12-19
DOI
10.7554/elife.12997
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice
- (2016) Michael B. Stout et al. Aging-US
- The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
- (2015) Yi Zhu et al. AGING CELL
- Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity
- (2015) Allyson K. Palmer et al. DIABETES
- JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
- (2015) Ming Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Insulin resistance and impaired adipogenesis
- (2015) Birgit Gustafson et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- White-to-brown metabolic conversion of human adipocytes by JAK inhibition
- (2014) Annie Moisan et al. NATURE CELL BIOLOGY
- The role of JAK–STAT signaling in adipose tissue function
- (2013) Allison J. Richard et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mechanisms and Metabolic Implications of Regional Differences among Fat Depots
- (2013) Tamara Tchkonia et al. Cell Metabolism
- Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
- (2013) Tamara Tchkonia et al. JOURNAL OF CLINICAL INVESTIGATION
- Adipogenic Differentiation Is Impaired in Replicative Senescent Human Subcutaneous Adipose-Derived Stromal/Progenitor Cells
- (2013) M. C. Mitterberger et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- A complex secretory program orchestrated by the inflammasome controls paracrine senescence
- (2013) Juan Carlos Acosta et al. NATURE CELL BIOLOGY
- Perilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytes
- (2013) Zhiqi Sun et al. Nature Communications
- A senescent cell bystander effect: senescence-induced senescence
- (2012) Glyn Nelson et al. AGING CELL
- The Intersection Between Aging and Cardiovascular Disease
- (2012) Brian J. North et al. CIRCULATION RESEARCH
- Effects of the activin A–myostatin–follistatin system on aging bone and muscle progenitor cells
- (2012) Matthew Bowser et al. EXPERIMENTAL GERONTOLOGY
- Cell Autonomous Lipin 1 Function Is Essential for Development and Maintenance of White and Brown Adipose Tissue
- (2012) K. Nadra et al. MOLECULAR AND CELLULAR BIOLOGY
- A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis
- (2012) Srdan Verstovsek et al. NEW ENGLAND JOURNAL OF MEDICINE
- JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis
- (2012) Claire Harrison et al. NEW ENGLAND JOURNAL OF MEDICINE
- Ncb5or Deficiency Increases Fatty Acid Catabolism and Oxidative Stress
- (2011) Ming Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- (2011) Darren J. Baker et al. NATURE
- Obesity, insulin resistance and free fatty acids
- (2011) Guenther Boden Current Opinion in Endocrinology Diabetes and Obesity
- Fat tissue, aging, and cellular senescence
- (2010) Tamara Tchkonia et al. AGING CELL
- Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms
- (2010) A. Quintas-Cardama et al. BLOOD
- Activin A Plays a Critical Role in Proliferation and Differentiation of Human Adipose Progenitors
- (2010) L.-E. Zaragosi et al. DIABETES
- Characterization of the Ligand Binding Functionality of the Extracellular Domain of Activin Receptor Type IIB
- (2010) Dianne Sako et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Aging, Depot Origin, and Preadipocyte Gene Expression
- (2010) Mark J. Cartwright et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Safety and Efficacy of INCB018424, a JAK1 and JAK2 Inhibitor, in Myelofibrosis
- (2010) Srdan Verstovsek et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen
- (2010) Jean-Philippe Coppé et al. PLoS One
- Regional differences in cellular mechanisms of adipose tissue gain with overfeeding
- (2010) Y. D. Tchoukalova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity
- (2010) Roger H. Unger et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Age-related changes in total and regional fat distribution
- (2009) Jennifer L. Kuk et al. AGEING RESEARCH REVIEWS
- Saturated with fat: new perspectives on lipotoxicity
- (2009) Jeanne Garbarino et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding
- (2009) Jennifer N Cash et al. EMBO JOURNAL
- Interferon γ Attenuates Insulin Signaling, Lipid Storage, and Differentiation in Human Adipocytes via Activation of the JAK/STAT Pathway
- (2009) Fiona C. McGillicuddy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The biology of activin: recent advances in structure, regulation and function
- (2009) Yin Xia et al. JOURNAL OF ENDOCRINOLOGY
- Dynamics of fat cell turnover in humans
- (2008) Kirsty L. Spalding et al. NATURE
- Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome
- (2008) M.-Y. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
- (2008) Jean-Philippe Coppé et al. PLOS BIOLOGY
- Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice
- (2007) Masashi Nakatani et al. FASEB JOURNAL
- Adipose Tissue Lipin-1 Expression Is Correlated with Peroxisome Proliferator-Activated Receptor α Gene Expression and Insulin Sensitivity in Healthy Young Men
- (2007) Jimmy Donkor et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search