Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice

Genome Integrity in Aging: Human Syndromes, Mouse Models, and Therapeutic Options

(2016) Wilbert P. Vermeij et al.   Annual Review of Pharmacology and Toxicology

The Cockayne Syndrome Natural History (CoSyNH) study: clinical findings in 102 individuals and recommendations for care

(2015) Brian T. Wilson et al.   GENETICS IN MEDICINE

miR-34 and p53: New Insights into a Complex Functional Relationship

(2015) Francisco Navarro et al.   PLoS One

Understanding nucleotide excision repair and its roles in cancer and ageing

(2014) Jurgen A. Marteijn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Priming of microglia in a DNA-repair deficient model of accelerated aging

(2014) Divya D.A. Raj et al.   NEUROBIOLOGY OF AGING

Cell-Autonomous Progeroid Changes in Conditional Mouse Models for Repair Endonuclease XPG Deficiency

(2014) Sander Barnhoorn et al.   PLoS Genetics

Life spanning murine gene expression profiles in relation to chronological and pathological aging in multiple organs

(2013) Martijs J. Jonker et al.   AGING CELL

Mutations in ERCC4, Encoding the DNA-Repair Endonuclease XPF, Cause Fanconi Anemia

(2013) Massimo Bogliolo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Malfunction of Nuclease ERCC1-XPF Results in Diverse Clinical Manifestations and Causes Cockayne Syndrome, Xeroderma Pigmentosum, and Fanconi Anemia

(2013) Kazuya Kashiyama et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Cockayne syndrome pathogenesis: Lessons from mouse models

(2013) Dick Jaarsma et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Spatio-temporal Analysis of Molecular Determinants of Neuronal Degeneration in the Aging Mouse Cerebellum

(2013) Erik L. de Graaf et al.   MOLECULAR & CELLULAR PROTEOMICS

Somatotropic Signaling: Trade-Offs Between Growth, Reproductive Development, and Longevity

(2013) Andrzej Bartke et al.   PHYSIOLOGICAL REVIEWS

Nucleotide Excision DNA Repair Is Associated With Age-Related Vascular Dysfunction

(2012) Matej Durik et al.   CIRCULATION

The Critical Role of Metabolic Pathways in Aging

(2012) N. Barzilai et al.   DIABETES

Accelerated Age-Related Cognitive Decline and Neurodegeneration, Caused by Deficient DNA Repair

(2011) N. Z. Borgesius et al.   JOURNAL OF NEUROSCIENCE

Caloric restriction

(2011) John R. Speakman et al.   MOLECULAR ASPECTS OF MEDICINE

Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice

(2010) Monique C. de Waard et al.   ACTA NEUROPATHOLOGICA

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

The ploidy conveyor of mature hepatocytes as a source of genetic variation

(2010) Andrew W. Duncan et al.   NATURE

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Endogenous versus Exogenous DNA Adducts: Their Role in Carcinogenesis, Epidemiology, and Risk Assessment

(2010) J. A. Swenberg et al.   TOXICOLOGICAL SCIENCES

Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse

(2009) William R Swindell   BMC GENOMICS

An Overview of Chemical Processes That Damage Cellular DNA: Spontaneous Hydrolysis, Alkylation, and Reactions with Radicals

(2009) Kent S. Gates   CHEMICAL RESEARCH IN TOXICOLOGY

Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity

(2009) George A. Garinis et al.   NATURE CELL BIOLOGY

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

DNA Damage, Aging, and Cancer

(2009) Jan H.J. Hoeijmakers   NEW ENGLAND JOURNAL OF MEDICINE

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

What is principal component analysis?

(2008) Markus Ringnér   NATURE BIOTECHNOLOGY

ADAMTS5−/− mice have less subchondral bone changes after induction of osteoarthritis through surgical instability: implications for a link between cartilage and subchondral bone changes

(2008) S.M. Botter et al.   OSTEOARTHRITIS AND CARTILAGE

Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms

(2008) Björn Schumacher et al.   PLoS Genetics