Signaling pathways controlling skeletal muscle mass

MST1, a key player, in enhancing fast skeletal muscle atrophy

(2013) Bin Wei et al.   BMC BIOLOGY

Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy

(2013) Perrine Castets et al.   Cell Metabolism

eIF3f: A central regulator of the antagonism atrophy/hypertrophy in skeletal muscle

(2013) Anthony M.J. Sanchez et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome

(2013) Marco Sandri   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Peroxisome Proliferator-activated Receptor γ Coactivator 1 (PGC-1)- and Estrogen-related Receptor (ERR)-induced Regulator in Muscle 1 (PERM1) Is a Tissue-specific Regulator of Oxidative Capacity in Skeletal Muscle Cells

(2013) Yoshitake Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders

(2013) Ruisheng Song et al.   NATURE

mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin

(2013) S. A. Kang et al.   SCIENCE

Trip12, a HECT domain E3 ubiquitin ligase, targets Sox6 for proteasomal degradation and affects fiber type-specific gene expression in muscle cells

(2013) Chung-Il An et al.   Skeletal Muscle

Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy

(2013) C Bentzinger et al.   Skeletal Muscle

Metformin, metabolic stress, and mitochondria. Focus on “A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells”

(2012) Mary C. Sugden et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

NF-κB Activation Is Required for the Transition of Pulmonary Inflammation to Muscle Atrophy

(2012) Ramon C. J. Langen et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

RETRACTED: The Ubiquitin Ligase Mul1 Induces Mitophagy in Skeletal Muscle in Response to Muscle-Wasting Stimuli

(2012) Sudarsanareddy Lokireddy et al.   Cell Metabolism

Ubiquitylation by Trim32 causes coupled loss of desmin, Z-bands, and thin filaments in muscle atrophy

(2012) Shenhav Cohen et al.   JOURNAL OF CELL BIOLOGY

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

(2012) D. W. Lamming et al.   SCIENCE

TAK-1/p38/nNFκB signaling inhibits myoblast differentiation by increasing levels of Activin A

(2012) Anne Trendelenburg et al.   Skeletal Muscle

Molecular Mechanisms and Treatment Options for Muscle Wasting Diseases

(2011) Markus A. Rüegg et al.   Annual Review of Pharmacology and Toxicology

Crosstalk between Glucocorticoid Receptor and Nutritional Sensor mTOR in Skeletal Muscle

(2011) Noriaki Shimizu et al.   Cell Metabolism

The SCF-Fbxo40 Complex Induces IRS1 Ubiquitination in Skeletal Muscle, Limiting IGF1 Signaling

(2011) Jun Shi et al.   DEVELOPMENTAL CELL

G i2 Signaling Promotes Skeletal Muscle Hypertrophy, Myoblast Differentiation, and Muscle Regeneration

(2011) G. C. Minetti et al.   Science Signaling

Recent advances in the biology and therapy of muscle wasting

(2010) David Glass et al.   Annals of the New York Academy of Sciences

Sepsis increases the expression and activity of the transcription factor Forkhead Box O 1 (FOXO1) in skeletal muscle by a glucocorticoid-dependent mechanism

(2010) Ira J. Smith et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The TWEAK–Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice

(2010) Ashwani Mittal et al.   JOURNAL OF CELL BIOLOGY

MuRF1 is a muscle fiber-type II associated factor and together with MuRF2 regulates type-II fiber trophicity and maintenance

(2010) Anselmo S. Moriscot et al.   JOURNAL OF STRUCTURAL BIOLOGY

Myostatin up-regulation is associated with the skeletal muscle response to hypoxic stimuli

(2010) Maurice Hayot et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Stimulation of skeletal muscle myofibrillar protein synthesis, p70 S6 kinase phosphorylation, and ribosomal protein S6 phosphorylation by inhibition of myostatin in mature mice

(2009) Stephen Welle et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Inducible activation of Akt increases skeletal muscle mass and force without satellite cell activation

(2009) Bert Blaauw et al.   FASEB JOURNAL

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

(2009) Shenhav Cohen et al.   JOURNAL OF CELL BIOLOGY

AMP-activated protein kinase enhances the expression of muscle-specific ubiquitin ligases despite its activation of IGF-1/Akt signaling in C2C12 myotubes

(2009) Jun F. Tong et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Inhibition of Atrogin-1/MAFbx Mediated MyoD Proteolysis Prevents Skeletal Muscle Atrophy In Vivo

(2009) Julie Lagirand-Cantaloube et al.   PLoS One

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dependence of dexamethasone-induced Akt/FOXO1 signaling, upregulation of MAFbx, and protein catabolism upon the glucocorticoid receptor

(2008) Weidong Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural Analysis of B-Box 2 from MuRF1: Identification of a Novel Self-Association Pattern in a RING-like Fold†‡

(2008) Michael Mrosek et al.   BIOCHEMISTRY

Branched-chain amino acids and arginine suppress MaFbx/atrogin-1 mRNA expression via mTOR pathway in C2C12 cell line

(2008) Elizabeth Henny Herningtyas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Fast/Glycolytic Muscle Fiber Growth Reduces Fat Mass and Improves Metabolic Parameters in Obese Mice

(2008) Yasuhiro Izumiya et al.   Cell Metabolism

The CUL7 E3 Ubiquitin Ligase Targets Insulin Receptor Substrate 1 for Ubiquitin-Dependent Degradation

(2008) Xinsong Xu et al.   MOLECULAR CELL

Role of β-Adrenoceptor Signaling in Skeletal Muscle: Implications for Muscle Wasting and Disease

(2008) Gordon S. Lynch et al.   PHYSIOLOGICAL REVIEWS